AR117281A1 - Formulación para administración colónica de un fármaco - Google Patents
Formulación para administración colónica de un fármacoInfo
- Publication number
- AR117281A1 AR117281A1 ARP190103591A ARP190103591A AR117281A1 AR 117281 A1 AR117281 A1 AR 117281A1 AR P190103591 A ARP190103591 A AR P190103591A AR P190103591 A ARP190103591 A AR P190103591A AR 117281 A1 AR117281 A1 AR 117281A1
- Authority
- AR
- Argentina
- Prior art keywords
- drug
- coating
- delayed release
- release
- formulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/606—Salicylic acid; Derivatives thereof having amino groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
Abstract
En una formulación de fármaco de liberación demorada que comprende un núcleo que contiene un fármaco y opcionalmente un recubrimiento de liberación demorada para liberación intestinal, la liberación del fármaco en el colon no se ve perjudicada por la ausencia de una capa media alcalina entre el núcleo y la capa exterior. El recubrimiento de liberación demorada que comprende un recubrimiento interior y opcionalmente una capa de aislamiento. El recubrimiento exterior comprende una mezcla de un polisacárido que se degrada enzimáticamente que es degradable por las enzimas colónicas seleccionado del grupo que consiste en almidón, amilosa, amilopectina, quitosán, sulfato de condroitina, ciclodextrina, dextrano, pululan, carragenina, escleroglucano, quitina, curdulan y levan; y un polímero entérico formador de película que tiene un umbral de pH de aproximadamente un pH 6 o superior; donde el polisacárido que se degrada enzimáticamente y el polímero entérico están presentes en el recubrimiento exterior en una proporción de más de 60:40.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18211141.9A EP3662900A1 (en) | 2018-12-07 | 2018-12-07 | Colonic drug delivery formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
AR117281A1 true AR117281A1 (es) | 2021-07-28 |
Family
ID=64661226
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP190103591A AR117281A1 (es) | 2018-12-07 | 2019-12-09 | Formulación para administración colónica de un fármaco |
Country Status (13)
Country | Link |
---|---|
US (1) | US20220016037A1 (es) |
EP (2) | EP3662900A1 (es) |
JP (1) | JP7423629B2 (es) |
KR (1) | KR20210100666A (es) |
CN (1) | CN113164400A (es) |
AR (1) | AR117281A1 (es) |
AU (1) | AU2019394740A1 (es) |
BR (1) | BR112021010913A2 (es) |
CA (1) | CA3122033A1 (es) |
EA (1) | EA202191431A1 (es) |
IL (1) | IL283719A (es) |
MA (1) | MA54376A (es) |
WO (1) | WO2020115257A1 (es) |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8812490D0 (en) | 1988-05-26 | 1988-06-29 | Agricultural & Food Res | Delayed release formulations |
GB8926639D0 (en) | 1989-11-24 | 1990-01-17 | Agricultural & Food Res | Delayed release formulations |
US5422121A (en) | 1990-11-14 | 1995-06-06 | Rohm Gmbh | Oral dosage unit form |
US5656290A (en) | 1993-02-26 | 1997-08-12 | The Procter & Gamble Company | Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery |
GB9722426D0 (en) | 1997-10-23 | 1997-12-24 | Univ London Pharmacy | Controlled release formulations |
GB9724186D0 (en) | 1997-11-14 | 1998-01-14 | British Tech Group | Low temperature coatings |
FI20000780A (fi) | 2000-04-03 | 2001-10-04 | Novasso Oy | Peroraalinen lääkemuoto lääkeaineen hallituksi vapauttamiseksi |
GB2367002A (en) | 2000-09-25 | 2002-03-27 | British Sugar Plc | Coating composition |
GB0203421D0 (en) | 2002-02-13 | 2002-04-03 | Alizyme Therapeutics Ltd | Composition |
US7670627B2 (en) | 2002-12-09 | 2010-03-02 | Salvona Ip Llc | pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients |
DE102005032806A1 (de) | 2005-07-12 | 2007-01-18 | Röhm Gmbh | Verwendung eines teilneutralisierten, anionischen (Meth)acrylat-Copolymers als Überzug für die Herstellung einer Arzneiform mit einer Wirkstofffreisetzung bei erniedrigten pH-Werten |
GB0607534D0 (en) * | 2006-04-13 | 2006-05-24 | Univ London Pharmacy | Colonic drug delivery formulation |
SI2152250T1 (sl) | 2007-05-07 | 2020-06-30 | Evonik Operations Gmbh | Trdne dozirne oblike, ki vsebujejo enterično oplaščenje s pospešenim sproščanjem zdravila |
EP2688557B1 (en) * | 2011-03-23 | 2017-08-23 | Ironshore Pharmaceuticals & Development, Inc. | Methods and compositions for treatment of attention deficit disorder |
CU24343B1 (es) * | 2012-04-30 | 2018-05-08 | Tillotts Pharma Ag | Formulación de fármaco de liberación retardada |
NO2659881T3 (es) | 2012-04-30 | 2018-04-28 | ||
AU2013404367B2 (en) * | 2013-10-29 | 2020-02-27 | Tillotts Pharma Ag | A delayed release drug formulation |
ES2874669T3 (es) * | 2016-02-09 | 2021-11-05 | Albireo Ab | Formulación oral de colestiramina y uso de la misma |
-
2018
- 2018-12-07 EP EP18211141.9A patent/EP3662900A1/en active Pending
-
2019
- 2019-12-05 US US17/309,558 patent/US20220016037A1/en active Pending
- 2019-12-05 BR BR112021010913-7A patent/BR112021010913A2/pt unknown
- 2019-12-05 WO PCT/EP2019/083912 patent/WO2020115257A1/en unknown
- 2019-12-05 KR KR1020217020598A patent/KR20210100666A/ko active Search and Examination
- 2019-12-05 JP JP2021532415A patent/JP7423629B2/ja active Active
- 2019-12-05 CN CN201980081039.1A patent/CN113164400A/zh active Pending
- 2019-12-05 EP EP19816319.8A patent/EP3890711A1/en active Pending
- 2019-12-05 AU AU2019394740A patent/AU2019394740A1/en active Pending
- 2019-12-05 MA MA054376A patent/MA54376A/fr unknown
- 2019-12-05 EA EA202191431A patent/EA202191431A1/ru unknown
- 2019-12-05 CA CA3122033A patent/CA3122033A1/en active Pending
- 2019-12-09 AR ARP190103591A patent/AR117281A1/es unknown
-
2021
- 2021-06-06 IL IL283719A patent/IL283719A/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2020115257A1 (en) | 2020-06-11 |
BR112021010913A2 (pt) | 2021-08-24 |
US20220016037A1 (en) | 2022-01-20 |
EA202191431A1 (ru) | 2021-09-13 |
EP3890711A1 (en) | 2021-10-13 |
MA54376A (fr) | 2022-03-16 |
TW202038916A (zh) | 2020-11-01 |
JP7423629B2 (ja) | 2024-01-29 |
JP2022515340A (ja) | 2022-02-18 |
CN113164400A (zh) | 2021-07-23 |
IL283719A (en) | 2021-07-29 |
AU2019394740A1 (en) | 2021-06-17 |
EP3662900A1 (en) | 2020-06-10 |
KR20210100666A (ko) | 2021-08-17 |
CA3122033A1 (en) | 2020-06-11 |
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