AR117281A1 - Formulación para administración colónica de un fármaco - Google Patents

Formulación para administración colónica de un fármaco

Info

Publication number
AR117281A1
AR117281A1 ARP190103591A ARP190103591A AR117281A1 AR 117281 A1 AR117281 A1 AR 117281A1 AR P190103591 A ARP190103591 A AR P190103591A AR P190103591 A ARP190103591 A AR P190103591A AR 117281 A1 AR117281 A1 AR 117281A1
Authority
AR
Argentina
Prior art keywords
drug
coating
delayed release
release
formulation
Prior art date
Application number
ARP190103591A
Other languages
English (en)
Inventor
Gonzalez Roberto Carlos Bravo
Felipe Varum
Original Assignee
Tillotts Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tillotts Pharma Ag filed Critical Tillotts Pharma Ag
Publication of AR117281A1 publication Critical patent/AR117281A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/606—Salicylic acid; Derivatives thereof having amino groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)

Abstract

En una formulación de fármaco de liberación demorada que comprende un núcleo que contiene un fármaco y opcionalmente un recubrimiento de liberación demorada para liberación intestinal, la liberación del fármaco en el colon no se ve perjudicada por la ausencia de una capa media alcalina entre el núcleo y la capa exterior. El recubrimiento de liberación demorada que comprende un recubrimiento interior y opcionalmente una capa de aislamiento. El recubrimiento exterior comprende una mezcla de un polisacárido que se degrada enzimáticamente que es degradable por las enzimas colónicas seleccionado del grupo que consiste en almidón, amilosa, amilopectina, quitosán, sulfato de condroitina, ciclodextrina, dextrano, pululan, carragenina, escleroglucano, quitina, curdulan y levan; y un polímero entérico formador de película que tiene un umbral de pH de aproximadamente un pH 6 o superior; donde el polisacárido que se degrada enzimáticamente y el polímero entérico están presentes en el recubrimiento exterior en una proporción de más de 60:40.
ARP190103591A 2018-12-07 2019-12-09 Formulación para administración colónica de un fármaco AR117281A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP18211141.9A EP3662900A1 (en) 2018-12-07 2018-12-07 Colonic drug delivery formulation

Publications (1)

Publication Number Publication Date
AR117281A1 true AR117281A1 (es) 2021-07-28

Family

ID=64661226

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP190103591A AR117281A1 (es) 2018-12-07 2019-12-09 Formulación para administración colónica de un fármaco

Country Status (14)

Country Link
US (1) US20220016037A1 (es)
EP (2) EP3662900A1 (es)
JP (1) JP7423629B2 (es)
KR (1) KR20210100666A (es)
CN (1) CN113164400A (es)
AR (1) AR117281A1 (es)
AU (1) AU2019394740A1 (es)
BR (1) BR112021010913A2 (es)
CA (1) CA3122033A1 (es)
EA (1) EA202191431A1 (es)
IL (1) IL283719A (es)
MA (1) MA54376A (es)
TW (1) TWI837237B (es)
WO (1) WO2020115257A1 (es)

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8812490D0 (en) 1988-05-26 1988-06-29 Agricultural & Food Res Delayed release formulations
GB8926639D0 (en) 1989-11-24 1990-01-17 Agricultural & Food Res Delayed release formulations
US5422121A (en) 1990-11-14 1995-06-06 Rohm Gmbh Oral dosage unit form
US5656290A (en) 1993-02-26 1997-08-12 The Procter & Gamble Company Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery
GB9722426D0 (en) 1997-10-23 1997-12-24 Univ London Pharmacy Controlled release formulations
GB9724186D0 (en) 1997-11-14 1998-01-14 British Tech Group Low temperature coatings
FI20000780A (fi) 2000-04-03 2001-10-04 Novasso Oy Peroraalinen lääkemuoto lääkeaineen hallituksi vapauttamiseksi
GB2367002A (en) 2000-09-25 2002-03-27 British Sugar Plc Coating composition
GB0203421D0 (en) 2002-02-13 2002-04-03 Alizyme Therapeutics Ltd Composition
US7670627B2 (en) 2002-12-09 2010-03-02 Salvona Ip Llc pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients
DE102005032806A1 (de) 2005-07-12 2007-01-18 Röhm Gmbh Verwendung eines teilneutralisierten, anionischen (Meth)acrylat-Copolymers als Überzug für die Herstellung einer Arzneiform mit einer Wirkstofffreisetzung bei erniedrigten pH-Werten
GB0607534D0 (en) 2006-04-13 2006-05-24 Univ London Pharmacy Colonic drug delivery formulation
US8998802B2 (en) * 2006-05-24 2015-04-07 Olympus Medical Systems Corp. Endoscope, endoscopic apparatus, and examination method using endoscope
SI2152250T1 (sl) 2007-05-07 2020-06-30 Evonik Operations Gmbh Trdne dozirne oblike, ki vsebujejo enterično oplaščenje s pospešenim sproščanjem zdravila
DK4011364T3 (da) * 2011-03-23 2024-03-18 Ironshore Pharmaceuticals & Dev Inc Fremgangsmåder og sammensætninger til behandling af ADD (Attention Deficit Disorder)
JOP20200144A1 (ar) * 2012-04-30 2017-06-16 Tillotts Pharma Ag تركيبة عقار ذو إطلاق متأخر
CU24343B1 (es) * 2012-04-30 2018-05-08 Tillotts Pharma Ag Formulación de fármaco de liberación retardada
EP3062776A1 (en) * 2013-10-29 2016-09-07 Tillotts Pharma AG A delayed release drug formulation
CN108601744B (zh) * 2016-02-09 2022-01-04 阿尔比里奥公司 口服考来烯胺制剂及其用途

Also Published As

Publication number Publication date
IL283719A (en) 2021-07-29
EP3662900A1 (en) 2020-06-10
JP2022515340A (ja) 2022-02-18
BR112021010913A2 (pt) 2021-08-24
KR20210100666A (ko) 2021-08-17
EA202191431A1 (ru) 2021-09-13
JP7423629B2 (ja) 2024-01-29
CA3122033A1 (en) 2020-06-11
WO2020115257A1 (en) 2020-06-11
US20220016037A1 (en) 2022-01-20
TWI837237B (zh) 2024-04-01
EP3890711A1 (en) 2021-10-13
AU2019394740A1 (en) 2021-06-17
CN113164400A (zh) 2021-07-23
TW202038916A (zh) 2020-11-01
MA54376A (fr) 2022-03-16

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