AR112840A1 - 3- fenilquinazolin-4(3h)-onas sustituidas y sus usos - Google Patents

3- fenilquinazolin-4(3h)-onas sustituidas y sus usos

Info

Publication number
AR112840A1
AR112840A1 ARP180102771A ARP180102771A AR112840A1 AR 112840 A1 AR112840 A1 AR 112840A1 AR P180102771 A ARP180102771 A AR P180102771A AR P180102771 A ARP180102771 A AR P180102771A AR 112840 A1 AR112840 A1 AR 112840A1
Authority
AR
Argentina
Prior art keywords
alkyl
optionally substituted
atom
fluorine atoms
hydrogen
Prior art date
Application number
ARP180102771A
Other languages
English (en)
Spanish (es)
Inventor
Boultadakis Arapinis Melissa Dr
Zorn Ludwig Dr
Thede Kai Dr
Giese Anja Dr
Lang Dieter Dr
Bender Eckhard Dr
Gaugaz Fabienne Zdenka Dr
Dietz Lisa Dr
Hahn Michael Dr
Borissoff Julian Dr
Jimenez Nunez Eloisa Dr
Original Assignee
Bayer Ag
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Bayer Pharma AG filed Critical Bayer Ag
Publication of AR112840A1 publication Critical patent/AR112840A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms
    • C07D239/91Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ARP180102771A 2017-09-29 2018-09-27 3- fenilquinazolin-4(3h)-onas sustituidas y sus usos AR112840A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17193995 2017-09-29

Publications (1)

Publication Number Publication Date
AR112840A1 true AR112840A1 (es) 2019-12-18

Family

ID=59997232

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP180102771A AR112840A1 (es) 2017-09-29 2018-09-27 3- fenilquinazolin-4(3h)-onas sustituidas y sus usos

Country Status (4)

Country Link
AR (1) AR112840A1 (fr)
TW (1) TW201922724A (fr)
UY (1) UY37907A (fr)
WO (1) WO2019063704A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021167883A1 (fr) * 2020-02-21 2021-08-26 The Children's Medical Center Corporation Méthode pour le traitement de l'asthme ou d'une maladie allergique
CN112370529B (zh) * 2020-11-30 2022-11-11 中国药科大学 一种治疗肺动脉高压的复方制剂与制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966781A (en) 1970-12-17 1976-06-29 Merck Sharp & Dohme (I.A.) Corporation Deuteration of functional group-containing hydrocarbons
JP4619545B2 (ja) 1999-03-17 2011-01-26 アストラゼネカ アクチボラグ アミド誘導体
GB0124627D0 (en) 2001-10-15 2001-12-05 Smithkline Beecham Plc Novel compounds
AU2003301662A1 (en) 2002-10-21 2004-05-13 Bristol-Myers Squibb Company Quinazolinones and derivatives thereof as factor xa inhibitors
CN101001845A (zh) * 2004-06-15 2007-07-18 阿斯利康(瑞典)有限公司 作为抗癌药物的取代喹唑酮
EP2091947A2 (fr) 2006-12-20 2009-08-26 Takeda San Diego, Inc. Activateurs de glucokinase
EP2675440B1 (fr) 2011-02-14 2020-03-25 Merck Sharp & Dohme Corp. Inhibiteurs de cystéine protéases, les cathepsines
AU2014234472A1 (en) 2013-03-20 2015-10-29 Bayer Pharma Aktiengesellschaft 3-acetylamino-1-(phenyl-heteroaryl-aminocarbonyl or phenyl-heteroaryl-carbonylamino)benzene derivatives for the treatment of hyperproliferative disorders
US9682961B2 (en) * 2013-12-06 2017-06-20 Carna Biosciences, Inc. Quinazoline derivative

Also Published As

Publication number Publication date
TW201922724A (zh) 2019-06-16
UY37907A (es) 2019-04-30
WO2019063704A1 (fr) 2019-04-04

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