AR110949A1 - Anticuerpo de envoltura anti-herv-k y sus usos - Google Patents

Anticuerpo de envoltura anti-herv-k y sus usos

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Publication number
AR110949A1
AR110949A1 ARP180100129A ARP180100129A AR110949A1 AR 110949 A1 AR110949 A1 AR 110949A1 AR P180100129 A ARP180100129 A AR P180100129A AR P180100129 A ARP180100129 A AR P180100129A AR 110949 A1 AR110949 A1 AR 110949A1
Authority
AR
Argentina
Prior art keywords
seq
antibody
herv
wrapping
patient
Prior art date
Application number
ARP180100129A
Other languages
English (en)
Original Assignee
Geneuro Sa
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geneuro Sa, Us Health filed Critical Geneuro Sa
Publication of AR110949A1 publication Critical patent/AR110949A1/es

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Abstract

Reivindicación 1: Un anticuerpo que reconoce la proteína de envoltura de HERV-K, en donde dicho anticuerpo se une al epítopo establecido en SEQ ID Nº 9. Reivindicación 2: El anticuerpo de acuerdo con la reivindicación 1, en donde: i) dicho anticuerpo que reconoce la proteína de envoltura de HERV-K comprende cada una de las 6 CDR ilustradas en SEQ ID Nº 1, SEQ ID Nº 2, SEQ ID Nº 3, SEQ ID Nº 4, SEQ ID Nº 5 y SEQ ID Nº 6. Reivindicación 7: Una composición farmacéutica que comprende el anticuerpo de acuerdo con cualquiera de las reivindicaciones 1 a 4 y un excipiente farmacéuticamente aceptable. Reivindicación 9: Un método para diagnosticar ELA en un paciente que comprende la etapa de poner en contacto una muestra biológica obtenida de dicho paciente con un anticuerpo anti-envoltura de HERV-K como se define en cualquiera de las reivindicaciones 1 a 4.
ARP180100129A 2017-01-20 2018-01-19 Anticuerpo de envoltura anti-herv-k y sus usos AR110949A1 (es)

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EP3351265A1 (en) * 2017-01-20 2018-07-25 Geneuro SA Anti-herv-k envelope antibody and uses thereof
EP4025303A1 (en) * 2019-09-04 2022-07-13 Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE) Herv inhibitors for use in treating tauopathies
WO2023212587A1 (en) * 2022-04-28 2023-11-02 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Recombinant polypeptides comprising single-domain antibodies targeting herv-k subtype hml-2

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GB2273099A (en) * 1992-11-10 1994-06-08 Asta Medica Ag Glycoprotein encoded by a human endogenous retrovirus K envelope gene
WO2004069174A2 (en) * 2003-01-31 2004-08-19 Slil Biomedical Corporation Monitoring and treatment of amyotrophic lateral sclerosis
FR2865403B1 (fr) * 2004-01-23 2009-06-12 Biomerieux Sa Composition pour le traitement d'une pathologie associee a la msrv/herv-w
US20090297530A1 (en) * 2006-05-22 2009-12-03 Feng Wang-Johanning Herv-k antigens, antibodies, and methods
FR2912314B1 (fr) * 2007-02-09 2012-08-03 Geneuro Sa Composition pharmaceutique comprenant des anticorps diriges contre l'enveloppe de herv-w.
WO2013059426A1 (en) * 2011-10-21 2013-04-25 The Regents Of The University Of California Human endogenous retrovirus peptides, antibodies to the peptides, and methods of use thereof
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UA119032C2 (uk) * 2012-10-02 2019-04-25 Женеро Са Фармацевтична композиція для лікування блокади ремієлінізації при захворюваннях, які пов'язані з експресією білка оболонки herv-w
CN103755805B (zh) * 2014-02-11 2015-08-12 中国疾病预防控制中心病毒病预防控制所 HIV-1 Env特异性的全人单克隆抗体
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WO2018136775A1 (en) 2018-07-26
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IL267955A (en) 2019-09-26
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AU2018210388B2 (en) 2024-05-23
WO2018136774A1 (en) 2018-07-26
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US20190345232A1 (en) 2019-11-14
US10981977B2 (en) 2021-04-20
JP7139340B2 (ja) 2022-09-20
KR20190119593A (ko) 2019-10-22
KR102599010B1 (ko) 2023-11-06
UA126677C2 (uk) 2023-01-11
AU2018210388A1 (en) 2019-08-01
EP3351265A1 (en) 2018-07-25
CN110678196A (zh) 2020-01-10
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