AR110949A1 - Anticuerpo de envoltura anti-herv-k y sus usos - Google Patents
Anticuerpo de envoltura anti-herv-k y sus usosInfo
- Publication number
- AR110949A1 AR110949A1 ARP180100129A ARP180100129A AR110949A1 AR 110949 A1 AR110949 A1 AR 110949A1 AR P180100129 A ARP180100129 A AR P180100129A AR P180100129 A ARP180100129 A AR P180100129A AR 110949 A1 AR110949 A1 AR 110949A1
- Authority
- AR
- Argentina
- Prior art keywords
- seq
- antibody
- herv
- wrapping
- patient
- Prior art date
Links
- 241000192019 Human endogenous retrovirus K Species 0.000 abstract 3
- 101710091045 Envelope protein Proteins 0.000 abstract 2
- 101710188315 Protein X Proteins 0.000 abstract 2
- 102100021696 Syncytin-1 Human genes 0.000 abstract 2
- 239000012472 biological sample Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
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- G01N2800/28—Neurological disorders
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Abstract
Reivindicación 1: Un anticuerpo que reconoce la proteína de envoltura de HERV-K, en donde dicho anticuerpo se une al epítopo establecido en SEQ ID Nº 9. Reivindicación 2: El anticuerpo de acuerdo con la reivindicación 1, en donde: i) dicho anticuerpo que reconoce la proteína de envoltura de HERV-K comprende cada una de las 6 CDR ilustradas en SEQ ID Nº 1, SEQ ID Nº 2, SEQ ID Nº 3, SEQ ID Nº 4, SEQ ID Nº 5 y SEQ ID Nº 6. Reivindicación 7: Una composición farmacéutica que comprende el anticuerpo de acuerdo con cualquiera de las reivindicaciones 1 a 4 y un excipiente farmacéuticamente aceptable. Reivindicación 9: Un método para diagnosticar ELA en un paciente que comprende la etapa de poner en contacto una muestra biológica obtenida de dicho paciente con un anticuerpo anti-envoltura de HERV-K como se define en cualquiera de las reivindicaciones 1 a 4.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17305062.6A EP3351265A1 (en) | 2017-01-20 | 2017-01-20 | Anti-herv-k envelope antibody and uses thereof |
Publications (1)
Publication Number | Publication Date |
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AR110949A1 true AR110949A1 (es) | 2019-05-22 |
Family
ID=58018037
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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ARP180100129A AR110949A1 (es) | 2017-01-20 | 2018-01-19 | Anticuerpo de envoltura anti-herv-k y sus usos |
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US (2) | US10723787B2 (es) |
EP (2) | EP3351265A1 (es) |
JP (1) | JP7139340B2 (es) |
KR (1) | KR102599010B1 (es) |
CN (1) | CN110678196B (es) |
AR (1) | AR110949A1 (es) |
AU (1) | AU2018210388C1 (es) |
BR (1) | BR112019014773A8 (es) |
CA (1) | CA3050286A1 (es) |
EA (1) | EA039460B1 (es) |
IL (1) | IL267955B1 (es) |
MX (1) | MX2019008648A (es) |
TW (1) | TWI793098B (es) |
UA (1) | UA126677C2 (es) |
WO (2) | WO2018136775A1 (es) |
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Publication number | Priority date | Publication date | Assignee | Title |
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EP3351265A1 (en) * | 2017-01-20 | 2018-07-25 | Geneuro SA | Anti-herv-k envelope antibody and uses thereof |
EP4025303A1 (en) * | 2019-09-04 | 2022-07-13 | Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE) | Herv inhibitors for use in treating tauopathies |
WO2023212587A1 (en) * | 2022-04-28 | 2023-11-02 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Recombinant polypeptides comprising single-domain antibodies targeting herv-k subtype hml-2 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2273099A (en) * | 1992-11-10 | 1994-06-08 | Asta Medica Ag | Glycoprotein encoded by a human endogenous retrovirus K envelope gene |
EP1613263A4 (en) * | 2003-01-31 | 2007-11-28 | Pathologica Llc | MONITORING AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS |
FR2865403B1 (fr) * | 2004-01-23 | 2009-06-12 | Biomerieux Sa | Composition pour le traitement d'une pathologie associee a la msrv/herv-w |
US20090297530A1 (en) * | 2006-05-22 | 2009-12-03 | Feng Wang-Johanning | Herv-k antigens, antibodies, and methods |
FR2912314B1 (fr) * | 2007-02-09 | 2012-08-03 | Geneuro Sa | Composition pharmaceutique comprenant des anticorps diriges contre l'enveloppe de herv-w. |
WO2013059426A1 (en) * | 2011-10-21 | 2013-04-25 | The Regents Of The University Of California | Human endogenous retrovirus peptides, antibodies to the peptides, and methods of use thereof |
US20150250864A1 (en) * | 2012-06-25 | 2015-09-10 | Board Of Regents, The University Of Texas System | Anti-cancer vaccines |
UA119032C2 (uk) * | 2012-10-02 | 2019-04-25 | Женеро Са | Фармацевтична композиція для лікування блокади ремієлінізації при захворюваннях, які пов'язані з експресією білка оболонки herv-w |
CN103755805B (zh) * | 2014-02-11 | 2015-08-12 | 中国疾病预防控制中心病毒病预防控制所 | HIV-1 Env特异性的全人单克隆抗体 |
WO2017059122A1 (en) * | 2015-09-29 | 2017-04-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human | Methods of treating and preventing amyotrophic lateral sclerosis |
WO2018044970A1 (en) * | 2016-08-31 | 2018-03-08 | University Of Rochester | Human monoclonal antibodies to human endogenous retrovirus k envelope (herv-k) and uses thereof |
EP3351265A1 (en) * | 2017-01-20 | 2018-07-25 | Geneuro SA | Anti-herv-k envelope antibody and uses thereof |
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2017
- 2017-01-20 EP EP17305062.6A patent/EP3351265A1/en not_active Withdrawn
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2018
- 2018-01-19 CA CA3050286A patent/CA3050286A1/en active Pending
- 2018-01-19 EA EA201991736A patent/EA039460B1/ru unknown
- 2018-01-19 KR KR1020197024261A patent/KR102599010B1/ko active IP Right Grant
- 2018-01-19 AU AU2018210388A patent/AU2018210388C1/en active Active
- 2018-01-19 IL IL267955A patent/IL267955B1/en unknown
- 2018-01-19 JP JP2019539822A patent/JP7139340B2/ja active Active
- 2018-01-19 EP EP18713060.4A patent/EP3570878A1/en active Pending
- 2018-01-19 BR BR112019014773A patent/BR112019014773A8/pt unknown
- 2018-01-19 UA UAA201909194A patent/UA126677C2/uk unknown
- 2018-01-19 AR ARP180100129A patent/AR110949A1/es unknown
- 2018-01-19 MX MX2019008648A patent/MX2019008648A/es unknown
- 2018-01-19 US US16/478,576 patent/US10723787B2/en active Active
- 2018-01-19 CN CN201880014059.2A patent/CN110678196B/zh active Active
- 2018-01-19 WO PCT/US2018/014489 patent/WO2018136775A1/en unknown
- 2018-01-19 WO PCT/US2018/014479 patent/WO2018136774A1/en active Application Filing
- 2018-01-22 TW TW107102219A patent/TWI793098B/zh active
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2020
- 2020-06-17 US US16/903,947 patent/US10981977B2/en active Active
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BR112019014773A2 (pt) | 2020-05-19 |
WO2018136774A1 (en) | 2018-07-26 |
WO2018136775A1 (en) | 2018-07-26 |
AU2018210388B2 (en) | 2024-05-23 |
TW201831518A (zh) | 2018-09-01 |
KR102599010B1 (ko) | 2023-11-06 |
MX2019008648A (es) | 2019-12-02 |
US20190345232A1 (en) | 2019-11-14 |
EA039460B1 (ru) | 2022-01-28 |
IL267955B1 (en) | 2024-09-01 |
UA126677C2 (uk) | 2023-01-11 |
CN110678196B (zh) | 2024-03-12 |
KR20190119593A (ko) | 2019-10-22 |
TWI793098B (zh) | 2023-02-21 |
AU2018210388C1 (en) | 2024-09-19 |
JP2020505383A (ja) | 2020-02-20 |
US10981977B2 (en) | 2021-04-20 |
AU2018210388A1 (en) | 2019-08-01 |
EA201991736A1 (ru) | 2019-12-30 |
BR112019014773A8 (pt) | 2020-06-09 |
IL267955A (en) | 2019-09-26 |
EP3570878A1 (en) | 2019-11-27 |
EP3351265A1 (en) | 2018-07-25 |
US20200308258A1 (en) | 2020-10-01 |
CA3050286A1 (en) | 2018-07-26 |
CN110678196A (zh) | 2020-01-10 |
US10723787B2 (en) | 2020-07-28 |
JP7139340B2 (ja) | 2022-09-20 |
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