AR109807A1 - Sistema de suministro transdérmico de pramipexol y usos del mismo - Google Patents
Sistema de suministro transdérmico de pramipexol y usos del mismoInfo
- Publication number
- AR109807A1 AR109807A1 ARP170102776A ARP170102776A AR109807A1 AR 109807 A1 AR109807 A1 AR 109807A1 AR P170102776 A ARP170102776 A AR P170102776A AR P170102776 A ARP170102776 A AR P170102776A AR 109807 A1 AR109807 A1 AR 109807A1
- Authority
- AR
- Argentina
- Prior art keywords
- pramipexol
- same
- polymers
- supply system
- drug
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Reivindicación 1: Un parche transdérmico para tratar la enfermedad de Parkinson, que comprende: (i) una capa que contiene fármaco; (ii) una capa de refuerzo; y (iii) una capa protectora, en donde la capa que contiene fármaco comprende pramipexol o una sal farmacéuticamente aceptable del mismo y dos o más polímeros, en donde por lo menos dos de los polímeros comprenden cada uno un grupo funcional carboxilo y/o un grupo funcional hidroxilo. Reivindicación 4: El parche transdérmico de conformidad con la reivindicación 1, caracterizado además porque los por lo menos dos polímeros cada uno comprende un polímero a base de acrilato.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2016/055866 WO2018067163A1 (en) | 2016-10-07 | 2016-10-07 | Pramipexole transdermal delivery system and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
AR109807A1 true AR109807A1 (es) | 2019-01-23 |
Family
ID=61830567
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP170102776A AR109807A1 (es) | 2016-10-07 | 2017-10-05 | Sistema de suministro transdérmico de pramipexol y usos del mismo |
Country Status (8)
Country | Link |
---|---|
US (2) | US10729679B2 (es) |
EP (1) | EP3522843B1 (es) |
JP (1) | JP6978417B2 (es) |
KR (1) | KR102699924B1 (es) |
CN (3) | CN109310526B (es) |
AR (1) | AR109807A1 (es) |
CA (1) | CA3003460A1 (es) |
WO (1) | WO2018067163A1 (es) |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US330922A (en) * | 1885-11-24 | Music-rack and walking-cane combined | ||
US5008110A (en) * | 1988-11-10 | 1991-04-16 | The Procter & Gamble Company | Storage-stable transdermal patch |
DE3937271A1 (de) * | 1989-11-09 | 1991-05-16 | Boehringer Ingelheim Kg | Transdermale applikation von 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzothiazol |
US20030170195A1 (en) * | 2000-01-10 | 2003-09-11 | Noven Pharmaceuticals, Inc. | Compositions and methods for drug delivery |
US20070225379A1 (en) * | 2001-08-03 | 2007-09-27 | Carrara Dario Norberto R | Transdermal delivery of systemically active central nervous system drugs |
DE10137082A1 (de) * | 2001-07-28 | 2003-02-13 | Hexal Ag | Matrixkontrolliertes transdermales therapeutisches System zur Anwendung von Pramiprexol und Ropinirol |
MY142204A (en) * | 2002-07-25 | 2010-10-29 | Pharmacia Corp | Pramipexole once-daily dosage form |
DE10333393A1 (de) * | 2003-07-23 | 2005-02-24 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System mit dem Wirkstoff Pramipexol |
DE10338174A1 (de) * | 2003-08-20 | 2005-03-24 | Lts Lohmann Therapie-Systeme Ag | Transdermale Arzneimittelzubereitungen mit Wirkstoffkombinationen zur Behandlung der Parkinson-Krankheit |
ES2626784T3 (es) * | 2003-10-28 | 2017-07-26 | Noven Pharmaceuticals, Inc. | Dispositivo de administración transdérmica de fármacos |
US8343538B2 (en) * | 2004-10-08 | 2013-01-01 | Noven Pharmaceuticals, Inc. | Compositions and methods for controlling the flux of a drug from a transdermal drug delivery systems |
CN101147739B (zh) | 2007-07-06 | 2010-12-08 | 北京康倍得医药技术开发有限公司 | 含罗替戈汀的组合物及其制药用途以及含该组合物的透皮贴剂 |
DE102012205493A1 (de) * | 2012-04-03 | 2013-10-10 | Acino Ag | Einen Dopamin-Agonisten enthaltendes transdermales Applikationssystem |
US9682068B2 (en) * | 2013-05-20 | 2017-06-20 | Mylan Inc. | Transdermal therapeutic system for extended dosing of pramipexole in treating neurological disorders |
CN103432104B (zh) * | 2013-08-09 | 2015-10-28 | 大连理工大学 | 一种含有普拉克索的透皮贴剂 |
CN103610666A (zh) | 2013-12-11 | 2014-03-05 | 中国药科大学 | 一种盐酸普拉克索透皮贴剂及其制备方法 |
EP3067050A1 (en) * | 2015-03-13 | 2016-09-14 | Acino AG | Transdermal therapeutic system with an overtape comprising two adhesive layers |
-
2016
- 2016-10-07 EP EP16918441.3A patent/EP3522843B1/en active Active
- 2016-10-07 CN CN201680084423.3A patent/CN109310526B/zh not_active Expired - Fee Related
- 2016-10-07 CN CN202210485428.4A patent/CN114796163A/zh active Pending
- 2016-10-07 CA CA3003460A patent/CA3003460A1/en active Pending
- 2016-10-07 WO PCT/US2016/055866 patent/WO2018067163A1/en unknown
- 2016-10-07 JP JP2018529579A patent/JP6978417B2/ja active Active
- 2016-10-07 KR KR1020187022840A patent/KR102699924B1/ko active IP Right Grant
- 2016-10-07 CN CN202210484939.4A patent/CN114668747A/zh active Pending
- 2016-12-19 US US15/384,286 patent/US10729679B2/en active Active
-
2017
- 2017-10-05 AR ARP170102776A patent/AR109807A1/es unknown
-
2020
- 2020-06-12 US US16/900,140 patent/US11291656B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN114796163A (zh) | 2022-07-29 |
CN114668747A (zh) | 2022-06-28 |
KR102699924B1 (ko) | 2024-08-29 |
WO2018067163A1 (en) | 2018-04-12 |
CN109310526A (zh) | 2019-02-05 |
JP6978417B2 (ja) | 2021-12-08 |
CA3003460A1 (en) | 2018-04-12 |
US11291656B2 (en) | 2022-04-05 |
EP3522843B1 (en) | 2022-09-21 |
US10729679B2 (en) | 2020-08-04 |
EP3522843A1 (en) | 2019-08-14 |
JP2019529332A (ja) | 2019-10-17 |
EP3522843A4 (en) | 2020-04-29 |
US20200368209A1 (en) | 2020-11-26 |
US20180098973A1 (en) | 2018-04-12 |
CN109310526B (zh) | 2022-05-17 |
KR20190065184A (ko) | 2019-06-11 |
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