AR095313A1 - Composiciones y métodos para aumentar la respuesta inmune contra patógenos entéricos - Google Patents

Composiciones y métodos para aumentar la respuesta inmune contra patógenos entéricos

Info

Publication number
AR095313A1
AR095313A1 ARP140101015A ARP140101015A AR095313A1 AR 095313 A1 AR095313 A1 AR 095313A1 AR P140101015 A ARP140101015 A AR P140101015A AR P140101015 A ARP140101015 A AR P140101015A AR 095313 A1 AR095313 A1 AR 095313A1
Authority
AR
Argentina
Prior art keywords
polypeptide
methods
immune response
response against
energic
Prior art date
Application number
ARP140101015A
Other languages
English (en)
Inventor
Abi-Ghanem Daad
R Pumford Neil
Hargis Billy
Bielke Lisa
B Faulkner Olivia
Berghman Luc
Layton Sherryll
Original Assignee
Univ Arkansas
Texas A & M Univ Sys
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Arkansas, Texas A & M Univ Sys filed Critical Univ Arkansas
Publication of AR095313A1 publication Critical patent/AR095313A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0275—Salmonella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/107—Vibrio
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1228—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K16/1232—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia from Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Vectores de vacuna capaces de inducir una respuesta inmune contra bacterias entéricas y métodos para usarlos. Los vectores de vacuna incluyen un polinucleótido que codifica un polipéptido PAL. El polipéptido PAL (polipéptido recombinante heterólogo) puede expresarse sobre la superficie del vector de vacuna. El vector de vacuna también puede incluir un segundo polipéptido que codifica un polipéptido inmunoestimulante tal como un polipéptido CD154 (ligando natural de CD40 y CD40: receptor del factor de necrosis tumoral THF) o un polipéptido HMGB1 (polipéptido de la caja 1 del equipo de gran movilidad). Composición farmacéutica.
ARP140101015A 2013-03-15 2014-03-14 Composiciones y métodos para aumentar la respuesta inmune contra patógenos entéricos AR095313A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361790301P 2013-03-15 2013-03-15

Publications (1)

Publication Number Publication Date
AR095313A1 true AR095313A1 (es) 2015-10-07

Family

ID=51581229

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP140101015A AR095313A1 (es) 2013-03-15 2014-03-14 Composiciones y métodos para aumentar la respuesta inmune contra patógenos entéricos

Country Status (18)

Country Link
US (3) US10376571B2 (es)
EP (2) EP2968423A4 (es)
JP (1) JP6530742B2 (es)
KR (1) KR102239207B1 (es)
CN (1) CN105142653B (es)
AR (1) AR095313A1 (es)
AU (1) AU2014239557B2 (es)
BR (1) BR112015023024B1 (es)
CA (1) CA2906079C (es)
CL (2) CL2015002741A1 (es)
EA (1) EA033538B1 (es)
HK (1) HK1219045A1 (es)
MX (1) MX2015012855A (es)
MY (1) MY173901A (es)
PH (1) PH12015502135A1 (es)
SG (1) SG11201507421XA (es)
WO (1) WO2014152508A1 (es)
ZA (1) ZA201506466B (es)

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SG11201809686SA (en) 2016-05-03 2018-11-29 Univ Arkansas Yeast vaccine vector including immunostimulatory and antigenic polypeptides and methods of using the same
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Also Published As

Publication number Publication date
PH12015502135B1 (en) 2016-01-25
KR20150130480A (ko) 2015-11-23
US20200297832A1 (en) 2020-09-24
US10376571B2 (en) 2019-08-13
JP6530742B2 (ja) 2019-06-12
BR112015023024A2 (pt) 2017-11-14
EP2968423A1 (en) 2016-01-20
WO2014152508A1 (en) 2014-09-25
EA201591798A1 (ru) 2016-06-30
CN105142653B (zh) 2019-11-15
ZA201506466B (en) 2023-05-31
EP2968423A4 (en) 2016-11-09
CA2906079A1 (en) 2014-09-25
CL2017002971A1 (es) 2018-03-16
MX2015012855A (es) 2016-07-21
AU2014239557A2 (en) 2016-01-14
HK1219045A1 (zh) 2017-03-24
KR102239207B1 (ko) 2021-04-09
AU2014239557A1 (en) 2015-10-15
US11013792B2 (en) 2021-05-25
EP3578190A1 (en) 2019-12-11
JP2016515133A (ja) 2016-05-26
PH12015502135A1 (en) 2016-01-25
CN105142653A (zh) 2015-12-09
EA033538B1 (ru) 2019-10-31
AU2014239557B2 (en) 2019-01-03
CA2906079C (en) 2022-08-23
US20190351042A1 (en) 2019-11-21
NZ711761A (en) 2021-08-27
SG11201507421XA (en) 2015-10-29
BR112015023024B1 (pt) 2022-04-19
CL2015002741A1 (es) 2016-02-12
US10716840B2 (en) 2020-07-21
US20160038581A1 (en) 2016-02-11
MY173901A (en) 2020-02-26

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