AR094416A1 - PROCESO PARA LA PREPARACIÓN EN FORMA CRISTALINA DE TIBOLONA, (7a,17a)-17-HIDROXI-7-METIL-19-NORPREGN-5(10)-EN-20-IN-3-ONA - Google Patents
PROCESO PARA LA PREPARACIÓN EN FORMA CRISTALINA DE TIBOLONA, (7a,17a)-17-HIDROXI-7-METIL-19-NORPREGN-5(10)-EN-20-IN-3-ONAInfo
- Publication number
- AR094416A1 AR094416A1 ARP140100096A ARP140100096A AR094416A1 AR 094416 A1 AR094416 A1 AR 094416A1 AR P140100096 A ARP140100096 A AR P140100096A AR P140100096 A ARP140100096 A AR P140100096A AR 094416 A1 AR094416 A1 AR 094416A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- norpregn
- tibolone
- tibolona
- hidroxi
- Prior art date
Links
- WZDGZWOAQTVYBX-XOINTXKNSA-N tibolone Chemical compound C([C@@H]12)C[C@]3(C)[C@@](C#C)(O)CC[C@H]3[C@@H]1[C@H](C)CC1=C2CCC(=O)C1 WZDGZWOAQTVYBX-XOINTXKNSA-N 0.000 title abstract 6
- 238000002360 preparation method Methods 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 229960001023 tibolone Drugs 0.000 abstract 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- 238000001035 drying Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000120A ITMI20130120A1 (it) | 2013-01-25 | 2013-01-25 | Processo per la preparazione in forma cristallina di tibolone, (7alfa,17alfa)-17-idrossi-7-metil-19-norpregn-5(10)-en-20-in-3-one |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR094416A1 true AR094416A1 (es) | 2015-07-29 |
Family
ID=47749930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140100096A AR094416A1 (es) | 2013-01-25 | 2014-01-10 | PROCESO PARA LA PREPARACIÓN EN FORMA CRISTALINA DE TIBOLONA, (7a,17a)-17-HIDROXI-7-METIL-19-NORPREGN-5(10)-EN-20-IN-3-ONA |
Country Status (5)
| Country | Link |
|---|---|
| AR (1) | AR094416A1 (pt) |
| BR (1) | BR102014001688A2 (pt) |
| ES (1) | ES2481140B1 (pt) |
| IT (1) | ITMI20130120A1 (pt) |
| MX (1) | MX2014000999A (pt) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE63051B1 (en) * | 1989-03-18 | 1995-03-22 | Akzo Nv | Pharmaceutical composition which contains a pharmaceutically suitable carrier and the compound having the structure (7alpha, 17alpha)-17-Hydroxy-7-methyl-19-nor-17-pregn-5(10)-en-20-yn- 3-one |
| CN100432093C (zh) * | 1998-10-16 | 2008-11-12 | 欧加农股份有限公司 | 包含（7α,17α)-17-羟基-7-甲基-19-去甲-17-孕-5（10）-烯-20-炔-3-酮的高纯度组合物 |
| IT1349813B1 (it) * | 2003-12-19 | 2008-12-01 | Processo per la preparazione di tibolone in forma di miscela polimorfica a composizione definita | |
| EP1883648A1 (en) * | 2005-05-23 | 2008-02-06 | Newchem S.p.A. | Process for the preparation of pure crystalline tibolone |
-
2013
- 2013-01-25 IT IT000120A patent/ITMI20130120A1/it unknown
-
2014
- 2014-01-10 AR ARP140100096A patent/AR094416A1/es not_active Application Discontinuation
- 2014-01-22 ES ES201430062A patent/ES2481140B1/es active Active
- 2014-01-23 BR BR102014001688A patent/BR102014001688A2/pt not_active Application Discontinuation
- 2014-01-24 MX MX2014000999A patent/MX2014000999A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI20130120A1 (it) | 2014-07-26 |
| MX2014000999A (es) | 2014-11-21 |
| ES2481140A1 (es) | 2014-07-29 |
| ES2481140B1 (es) | 2015-05-06 |
| BR102014001688A2 (pt) | 2016-11-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |