AR088799A1 - Derivados de carboxamida y urea a base de pirazolilos sustituidos que contienen una porcion fenilo sustituida con un grupo que contiene so₂ como ligandos del receptor de vanilloide - Google Patents
Derivados de carboxamida y urea a base de pirazolilos sustituidos que contienen una porcion fenilo sustituida con un grupo que contiene so₂ como ligandos del receptor de vanilloideInfo
- Publication number
- AR088799A1 AR088799A1 ARP120104205A ARP120104205A AR088799A1 AR 088799 A1 AR088799 A1 AR 088799A1 AR P120104205 A ARP120104205 A AR P120104205A AR P120104205 A ARP120104205 A AR P120104205A AR 088799 A1 AR088799 A1 AR 088799A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- group
- substituted
- pirazolils
- fenile
- Prior art date
Links
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical class NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 1
- 150000003857 carboxamides Chemical class 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 9
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 3
- 101100495923 Schizosaccharomyces pombe (strain 972 / ATCC 24843) chr2 gene Proteins 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P1/12—Antidiarrhoeals
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Virology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Obesity (AREA)
- Biotechnology (AREA)
- Otolaryngology (AREA)
- Ophthalmology & Optometry (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11008927 | 2011-11-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR088799A1 true AR088799A1 (es) | 2014-07-10 |
Family
ID=47143914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120104205A AR088799A1 (es) | 2011-11-09 | 2012-11-08 | Derivados de carboxamida y urea a base de pirazolilos sustituidos que contienen una porcion fenilo sustituida con un grupo que contiene so₂ como ligandos del receptor de vanilloide |
Country Status (13)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3113772B8 (en) | 2014-03-07 | 2020-11-25 | Biocryst Pharmaceuticals, Inc. | Trifluoromethyl substituted pyrazoles as human plasma kallikrein inhibitors |
| KR101909092B1 (ko) | 2014-11-24 | 2018-10-17 | (주) 메디프론디비티 | 바닐로이드 수용체 리간드 ii로서의 치환된 옥사졸계 및 싸이아졸계 카복스아미드 및 우레아 유도체 |
| CN114920697A (zh) * | 2022-05-16 | 2022-08-19 | 河南应用技术职业学院 | 杂环基取代的茚满丙酰胺类化合物及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010127855A1 (en) | 2009-05-07 | 2010-11-11 | Grünenthal GmbH | Substituted aromatic carboxamide and urea derivatives as vanilloid receptor ligands |
| PE20120374A1 (es) | 2009-05-07 | 2012-05-13 | Gruenenthal Chemie | Fenilureas y fenilamidas como ligandos del receptor de vanilloides |
-
2012
- 2012-11-08 JP JP2014540456A patent/JP2014532744A/ja not_active Withdrawn
- 2012-11-08 MX MX2014005233A patent/MX2014005233A/es not_active Application Discontinuation
- 2012-11-08 WO PCT/EP2012/072143 patent/WO2013068464A1/en active Application Filing
- 2012-11-08 HK HK15102581.4A patent/HK1202117A1/xx unknown
- 2012-11-08 AR ARP120104205A patent/AR088799A1/es unknown
- 2012-11-08 KR KR1020147015421A patent/KR20140091041A/ko not_active Withdrawn
- 2012-11-08 CA CA2854424A patent/CA2854424A1/en not_active Abandoned
- 2012-11-08 CN CN201280055221.8A patent/CN104066720A/zh active Pending
- 2012-11-08 AU AU2012334068A patent/AU2012334068A1/en not_active Abandoned
- 2012-11-08 BR BR112014011108A patent/BR112014011108A2/pt not_active IP Right Cessation
- 2012-11-08 TW TW101141483A patent/TW201326135A/zh unknown
- 2012-11-08 EP EP12783220.2A patent/EP2776401A1/en not_active Withdrawn
- 2012-11-08 IN IN865KON2014 patent/IN2014KN00865A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2776401A1 (en) | 2014-09-17 |
| MX2014005233A (es) | 2014-08-22 |
| CA2854424A1 (en) | 2013-05-16 |
| KR20140091041A (ko) | 2014-07-18 |
| TW201326135A (zh) | 2013-07-01 |
| CN104066720A (zh) | 2014-09-24 |
| WO2013068464A1 (en) | 2013-05-16 |
| BR112014011108A2 (pt) | 2017-05-16 |
| IN2014KN00865A (enrdf_load_stackoverflow) | 2015-10-02 |
| HK1202117A1 (en) | 2015-09-18 |
| JP2014532744A (ja) | 2014-12-08 |
| AU2012334068A1 (en) | 2014-05-22 |
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| AR088799A1 (es) | Derivados de carboxamida y urea a base de pirazolilos sustituidos que contienen una porcion fenilo sustituida con un grupo que contiene so₂ como ligandos del receptor de vanilloide | |
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