AR088369A1 - Sistema de administracion de farmaco de dos fases - Google Patents

Sistema de administracion de farmaco de dos fases

Info

Publication number
AR088369A1
AR088369A1 ARP120103874A ARP120103874A AR088369A1 AR 088369 A1 AR088369 A1 AR 088369A1 AR P120103874 A ARP120103874 A AR P120103874A AR P120103874 A ARP120103874 A AR P120103874A AR 088369 A1 AR088369 A1 AR 088369A1
Authority
AR
Argentina
Prior art keywords
hydrogel
particles
active ingredient
phase
administration system
Prior art date
Application number
ARP120103874A
Other languages
English (en)
Inventor
Jrgen Maier Hans
Original Assignee
Rp Scherer Technologies Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rp Scherer Technologies Llc filed Critical Rp Scherer Technologies Llc
Publication of AR088369A1 publication Critical patent/AR088369A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Abstract

Reivindicación 1: Una composición farmacéutica para la administración oral, que comprende: un hidrogel semisólido que tiene un contenido de agua de al menos el 20% en peso, en base al peso total del hidrogel, una pluralidad de partículas recubiertas que contienen ingrediente activo dispersas en dicho hidrogel, donde se activa la desintegración o disolución del recubrimiento de dichas partículas por exposición a un rango de pH particular y como resultado el ingrediente activo es liberado, y el hidrogel tiene un pH lo suficientemente diferente del pH que activa la desintegración o disolución del recubrimiento de las partículas para evitar la liberación del ingrediente activo de las partículas en el hidrogel.
ARP120103874A 2011-10-19 2012-10-18 Sistema de administracion de farmaco de dos fases AR088369A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161548837P 2011-10-19 2011-10-19

Publications (1)

Publication Number Publication Date
AR088369A1 true AR088369A1 (es) 2014-05-28

Family

ID=48135086

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP120103874A AR088369A1 (es) 2011-10-19 2012-10-18 Sistema de administracion de farmaco de dos fases

Country Status (9)

Country Link
US (1) US9314441B2 (es)
EP (1) EP2768488A4 (es)
JP (1) JP2014530855A (es)
CN (1) CN103957894A (es)
AR (1) AR088369A1 (es)
AU (1) AU2012326513B2 (es)
BR (1) BR112014009547A8 (es)
CA (1) CA2852447A1 (es)
WO (1) WO2013058996A1 (es)

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3419657A (en) 1964-06-23 1968-12-31 Dagra Nv Iodopanoic acid in a hydrogel
US4837255A (en) 1987-03-10 1989-06-06 Ciba-Geigy Corporation Palatable hypocholesterolaemic gel formulation containing a pharmaceutically acceptable non-digestible anion exchange resin
US5030454A (en) * 1987-10-26 1991-07-09 Alza Corporation Method for delivering drug in tiny pills in liquid carrier
JPH04149716A (ja) * 1990-10-15 1992-05-22 Fujitsu Ltd 情報処理装置
EP0596962A4 (en) * 1991-07-24 1997-01-15 Enzacor Pty Ltd Therapeutic compositions and methods.
US5364634A (en) * 1991-11-08 1994-11-15 Southwest Research Institute Controlled-release PH sensitive capsule and adhesive system and method
IL108366A (en) 1993-03-11 1999-11-30 Taro Vit Ind Ltd Semi-solid pharmaceutical compounds and a device for their use
SE9301489D0 (sv) * 1993-04-30 1993-04-30 Ab Astra Veterinary composition
IT1273742B (it) * 1994-08-01 1997-07-09 Lifegroup Spa Composizioni ad elevata bioadesivita' e mucoadesivita' utili per il trattamento di epitali e mucose
DE19529862A1 (de) 1995-08-14 1997-02-20 Rhone Poulenc Rorer Gmbh Pharmazeutische, oral anwendbare Zubereitung
US6365180B1 (en) 1998-01-20 2002-04-02 Glenn A. Meyer Oral liquid compositions
US6071523A (en) * 1998-06-03 2000-06-06 Taro Pharmaceuticals Industries, Ltd. Spill resistant pharmaceutical compositions in semi-solid form
CA2243619A1 (fr) 1998-07-17 2000-01-17 Universite De Sherbrooke Hydrogels polyioniques a base de xanthane et chitosane pour stabilisation et relargage controle des vitamines
EP1124587A1 (en) * 1999-08-27 2001-08-22 Department of National Defence Hydrogel wound dressing containing liposome-encapsulated therapeutic agent
DE10224086A1 (de) 2002-05-31 2003-12-11 Bayer Ag Pharmazeutische Zubereitungen zur oralen Anwendung enthaltend wirkstoffbeladene Ionentauscherharze sowie strukturviskose Gelbildner als Verdicker
WO2004004690A1 (en) * 2002-07-03 2004-01-15 Abbott Laboratories Liquid dosage forms of proton pump inhibitors
US7670627B2 (en) * 2002-12-09 2010-03-02 Salvona Ip Llc pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients
US20040265359A1 (en) 2003-04-17 2004-12-30 Sacks Gordon S. Oral delivery formulations of L-glutamine
US20080226705A1 (en) 2004-03-31 2008-09-18 Soltero Richard A Gel delivery system for oral administration of medicaments
WO2005107713A2 (en) 2004-05-11 2005-11-17 Egalet A/S Swellable dosage form comprising gellan gum
US9492400B2 (en) * 2004-11-04 2016-11-15 Massachusetts Institute Of Technology Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
JP4987261B2 (ja) 2005-07-13 2012-07-25 株式会社 メドレックス ゲル状経口製剤
DOP2006000274A (es) 2005-12-14 2007-10-15 Sanofi Aventis Us Llc Formulación de suspensión de fexofenadina
JP2007252341A (ja) * 2006-03-24 2007-10-04 Well Haamonii:Kk 粉末嚥下補助食品
JP2008125435A (ja) * 2006-11-21 2008-06-05 Well Haamonii:Kk ゲル形成性組成物及びこの組成物を含有するゲル
US20080171110A1 (en) * 2007-01-17 2008-07-17 Geoffrey Catherwood Stuart Solids package
JP2009007262A (ja) * 2007-06-26 2009-01-15 Toyo Capsule Kk ビスホスホネート製剤
JP5320091B2 (ja) * 2009-02-02 2013-10-23 大蔵製薬株式会社 医薬成分が長期安定化された経口投与医薬ゼリー製剤
CA2838006C (en) * 2011-06-07 2020-06-02 Gelesis Ip, Lp Method for producing hydrogels

Also Published As

Publication number Publication date
BR112014009547A8 (pt) 2018-01-23
US9314441B2 (en) 2016-04-19
CA2852447A1 (en) 2013-04-25
AU2012326513A1 (en) 2014-05-01
AU2012326513B2 (en) 2016-03-17
WO2013058996A1 (en) 2013-04-25
EP2768488A1 (en) 2014-08-27
EP2768488A4 (en) 2015-04-15
US20130098797A1 (en) 2013-04-25
JP2014530855A (ja) 2014-11-20
CN103957894A (zh) 2014-07-30
BR112014009547A2 (pt) 2017-04-18

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