AR083658A1 - Composicion nasal de metilcobalamina y el proceso para preparar la misma - Google Patents

Composicion nasal de metilcobalamina y el proceso para preparar la misma

Info

Publication number
AR083658A1
AR083658A1 ARP110104028A ARP110104028A AR083658A1 AR 083658 A1 AR083658 A1 AR 083658A1 AR P110104028 A ARP110104028 A AR P110104028A AR P110104028 A ARP110104028 A AR P110104028A AR 083658 A1 AR083658 A1 AR 083658A1
Authority
AR
Argentina
Prior art keywords
composition
metilcobalamine
nasal
prepare
same
Prior art date
Application number
ARP110104028A
Other languages
English (en)
Inventor
Ketan R Patel
Milan R Patel
Prakashchandra J Shah
Original Assignee
Troikaa Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Troikaa Pharmaceuticals Ltd filed Critical Troikaa Pharmaceuticals Ltd
Publication of AR083658A1 publication Critical patent/AR083658A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)

Abstract

Reivindicación 1: Se reivindica una composición acuosa estable de uso intranasal que incluye Metilcobalamina a una concentración de entre 500 mcg/0,1 ml y 1500 mcg/0,1, ml, co-solventes/agentes solubilizantes, o sus combinaciones en agua y opcionalmente agentes para el mejoramiento de la penetración, opcionalmente agentes de conservación, agentes mucoadhesivos, agentes quelantes, humectantes, antioxidantes, o sus combinaciones, composición ésta que tiene un pH de entre 5 y 7 y una viscosidad de entre 1 y 200 Cps.
ARP110104028A 2010-10-29 2011-10-31 Composicion nasal de metilcobalamina y el proceso para preparar la misma AR083658A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN2169MU2010 2010-10-29

Publications (1)

Publication Number Publication Date
AR083658A1 true AR083658A1 (es) 2013-03-13

Family

ID=45350421

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP110104028A AR083658A1 (es) 2010-10-29 2011-10-31 Composicion nasal de metilcobalamina y el proceso para preparar la misma

Country Status (20)

Country Link
EP (1) EP2632430B1 (es)
JP (1) JP5843873B2 (es)
CN (1) CN103384513B (es)
AP (1) AP3814A (es)
AR (1) AR083658A1 (es)
BR (1) BR112013010049B1 (es)
CO (1) CO6801717A2 (es)
CU (1) CU24142B1 (es)
DK (1) DK2632430T3 (es)
EA (1) EA024475B1 (es)
ES (1) ES2686299T3 (es)
HU (1) HUE039349T2 (es)
MX (1) MX337365B (es)
MY (1) MY163106A (es)
PE (1) PE20131137A1 (es)
PL (1) PL2632430T3 (es)
PT (1) PT2632430T (es)
UA (1) UA111342C2 (es)
WO (1) WO2012056299A1 (es)
ZA (1) ZA201303024B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3474842A4 (en) * 2016-06-24 2020-01-29 Opiant Pharmaceuticals, Inc. COMPOSITIONS, DEVICES AND METHODS FOR THE TREATMENT OF ALCOHOL RELATED DISORDER
JP7312698B2 (ja) 2016-11-18 2023-07-21 オーピアント ファーマシューティカルズ， インコーポレイテッド オピオイド過剰摂取を処置するための組成物および方法
EP3576754A4 (en) * 2017-02-06 2020-12-30 Torrent Pharmaceuticals Limited INTRANASAL COMPOSITION OF METHYLCOBALAMIN
MX2019014298A (es) * 2017-06-09 2020-02-03 Exelixis Inc Formas de dosificacion liquida para tratar el cancer.
GB202013645D0 (en) 2020-08-31 2020-10-14 Innotesto Bvba Pharmacetical compositions for the nasal administration of a colbalamin compound

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT376879B (de) * 1982-10-27 1985-01-10 Gerot Pharmazeutika Verfahren zur herstellung einer injektionsloesung
US4724231A (en) * 1985-04-16 1988-02-09 Nastech Pharmaceutical, Inc. Nasel compositions containing vitamin B12
ES2074396B1 (es) * 1993-03-24 1996-04-01 Farmalider Sa Sistema de administracion nasal de cianocobalamina (vitamina b12).
BE1007839A6 (nl) * 1993-12-20 1995-10-31 Merkus Franciscus W H M Prof Farmaceutische compositie voor de nasale toediening van hydroxocobalamine.
US7229636B1 (en) * 2003-03-04 2007-06-12 Nastech Pharmaceutical Company Inc. Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
JP4753717B2 (ja) * 2003-05-07 2011-08-24 エーザイ・アール・アンド・ディー・マネジメント株式会社 メチルコバラミン含有凍結乾燥製剤及びその製造方法
US20070111964A1 (en) * 2005-08-17 2007-05-17 Fleming And Company, Pharmaceuticals Vitamin B12 nasal spray and method of use
KR20140101010A (ko) * 2006-06-23 2014-08-18 파 파마슈티컬, 인크. 비내 전달용 시아노코발라민 저점도 수성 제형
US20090012039A1 (en) * 2007-03-16 2009-01-08 Stan Kurtz Use of methylcobalamin nasal spray to treat disorders
DE102007012644A1 (de) * 2007-03-16 2008-09-18 Bayer Healthcare Ag Stabilisierung von Vitamin B12

Also Published As

Publication number Publication date
EA024475B1 (ru) 2016-09-30
AP3814A (en) 2016-09-30
CN103384513A (zh) 2013-11-06
BR112013010049A2 (pt) 2018-01-09
EA201390623A1 (ru) 2013-09-30
WO2012056299A1 (en) 2012-05-03
ZA201303024B (en) 2014-01-29
MX2013004846A (es) 2013-10-01
PE20131137A1 (es) 2013-10-03
CN103384513B (zh) 2016-01-13
ES2686299T3 (es) 2018-10-17
JP5843873B2 (ja) 2016-01-13
EP2632430A1 (en) 2013-09-04
AP2013006837A0 (en) 2013-04-30
DK2632430T3 (en) 2018-09-17
PL2632430T3 (pl) 2018-11-30
JP2013540805A (ja) 2013-11-07
MX337365B (es) 2016-02-29
HUE039349T2 (hu) 2018-12-28
CO6801717A2 (es) 2013-11-29
MY163106A (en) 2017-08-15
UA111342C2 (uk) 2016-04-25
EP2632430B1 (en) 2018-06-06
CU24142B1 (es) 2015-12-23
CU20130062A7 (es) 2013-10-29
PT2632430T (pt) 2018-10-19
BR112013010049B1 (pt) 2021-07-13

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