AR080294A1 - Composiciones dirigidas a mejorar la solubilidad y administracion de los compuestos activos de magnolia - Google Patents
Composiciones dirigidas a mejorar la solubilidad y administracion de los compuestos activos de magnoliaInfo
- Publication number
- AR080294A1 AR080294A1 ARP110100555A ARP110100555A AR080294A1 AR 080294 A1 AR080294 A1 AR 080294A1 AR P110100555 A ARP110100555 A AR P110100555A AR P110100555 A ARP110100555 A AR P110100555A AR 080294 A1 AR080294 A1 AR 080294A1
- Authority
- AR
- Argentina
- Prior art keywords
- solubility
- administration
- magnolia
- improve
- active compounds
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title 1
- 241000218378 Magnolia Species 0.000 abstract 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- 239000004480 active ingredient Substances 0.000 abstract 3
- VVOAZFWZEDHOOU-UHFFFAOYSA-N magnolol Chemical compound OC1=CC=C(CC=C)C=C1C1=CC(CC=C)=CC=C1O VVOAZFWZEDHOOU-UHFFFAOYSA-N 0.000 abstract 3
- OYAQUBKYAKSHOA-UHFFFAOYSA-N 2-(2-hydroxy-5-propylphenyl)-4-propylphenol Chemical compound CCCC1=CC=C(O)C(C=2C(=CC=C(CCC)C=2)O)=C1 OYAQUBKYAKSHOA-UHFFFAOYSA-N 0.000 abstract 2
- FDVJJYZMLOZRGE-UHFFFAOYSA-N 4-butyl-2-(5-butyl-2-hydroxyphenyl)phenol Chemical compound CCCCC1=CC=C(O)C(C=2C(=CC=C(CCCC)C=2)O)=C1 FDVJJYZMLOZRGE-UHFFFAOYSA-N 0.000 abstract 1
- BYTORXDZJWWIKR-UHFFFAOYSA-N Hinokiol Natural products CC(C)c1cc2CCC3C(C)(CO)C(O)CCC3(C)c2cc1O BYTORXDZJWWIKR-UHFFFAOYSA-N 0.000 abstract 1
- FVYXIJYOAGAUQK-UHFFFAOYSA-N honokiol Chemical compound C1=C(CC=C)C(O)=CC=C1C1=CC(CC=C)=CC=C1O FVYXIJYOAGAUQK-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Birds (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Emergency Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
Métodos para el mejoramiento de la solubilidad y administracion de uno o más de los ingredientes activos hallados en el extracto de magnolia o uno de sus análogos sintéticos, en una composicion de uso oral. Reivindicacion 1: Una composicion de uso oral caracterizada porque incluye entre 0,05 y 10% en peso de propilenglicol; entre 0,05 y 5% en peso de al menos uno o más de los ingredientes activos hallados en el extracto de magnolia o uno de sus análogos sintéticos, donde al menos uno de los uno o más ingredientes activos es seleccionado a partir del grupo constituido por extracto de magnolia, magnolol, honokiol, tetrahidromagnolol, tetrahidrohonokiol (propilhonokiol), 5,5'-di-n-butil-bifenil-2,2'-diol y una combinacion de dos o más de ellos; y un vehículo oralmente aceptable.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30766410P | 2010-02-24 | 2010-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR080294A1 true AR080294A1 (es) | 2012-03-28 |
Family
ID=43768879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP110100555A AR080294A1 (es) | 2010-02-24 | 2011-02-24 | Composiciones dirigidas a mejorar la solubilidad y administracion de los compuestos activos de magnolia |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9801940B2 (es) |
| EP (1) | EP2523676B1 (es) |
| JP (1) | JP5665888B2 (es) |
| CN (1) | CN102762219B (es) |
| AR (1) | AR080294A1 (es) |
| AU (1) | AU2011220789B2 (es) |
| BR (1) | BR112012019997A2 (es) |
| CA (1) | CA2788423A1 (es) |
| CO (1) | CO6592076A2 (es) |
| MX (1) | MX2012009139A (es) |
| PH (1) | PH12012501620A1 (es) |
| RU (2) | RU2015114797A (es) |
| SG (1) | SG183117A1 (es) |
| TW (1) | TWI422382B (es) |
| WO (1) | WO2011106492A1 (es) |
| ZA (1) | ZA201206068B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI459957B (zh) * | 2010-02-24 | 2014-11-11 | 美國棕欖公司 | 口腔保健組成物 |
| PH12013501147A1 (en) | 2010-12-21 | 2016-06-03 | Colgate Palmolive Co | Halogenated biphenols as antibacterial agents |
| BR112014005439A2 (pt) * | 2011-09-08 | 2017-04-04 | Colgate Palmolive Co | composições de higiene bucal |
| EP2793812A1 (en) * | 2011-12-02 | 2014-10-29 | Colgate-Palmolive Company | Oral care compositions comprising n-butyl magnolol and isobutyl magnolol |
| MX340815B (es) * | 2011-12-02 | 2016-07-27 | Colgate Palmolive Co | Composicion de cuidado bucal que comprende isobutil magnolol. |
| CN104023698B (zh) * | 2011-12-15 | 2016-10-05 | 高露洁-棕榄公司 | 溶解的厚朴酚类似物 |
| CA2857648A1 (en) * | 2011-12-15 | 2013-06-20 | Colgate-Palmolive Company | Oral care or cleanser composition comprising solubilized magnolol analogs and ppg-1- peg-9 lauryl glycol ether |
| BR112014014207B1 (pt) * | 2011-12-15 | 2018-02-14 | Colgate-Palmolive Company | Composição compreendendo análogos de magnolol solubilizados |
| RU2014129908A (ru) | 2011-12-20 | 2016-02-10 | Колгейт-Палмолив Компани | Способы получения аналогов магнолола |
| US9000231B2 (en) | 2011-12-20 | 2015-04-07 | Colgate-Palmolive Company | Processes for making magnolol and derivatives thereof |
| JP2015508817A (ja) * | 2012-03-02 | 2015-03-23 | コルゲート・パーモリブ・カンパニーColgate−Palmolive Company | オーラル・ケア組成物 |
| EP2948220B1 (en) | 2013-01-23 | 2018-07-04 | Colgate-Palmolive Company | Processes for making magnolol derivatives |
| WO2014131191A1 (en) * | 2013-03-01 | 2014-09-04 | Johnson & Johnson Consumer Companies, Inc. | A composition containing honokiol and/or magnolol and uses thereof |
| MX388490B (es) * | 2015-07-14 | 2025-03-20 | Wrigley W M Jun Co | Extracto de corteza de magnolia como ligando hidrofobico para remocion preferencial de bacterias gram negativas de la cavidad oral. |
| GB201907225D0 (en) * | 2019-05-22 | 2019-07-03 | Cosmetic Warriors Ltd | Composition |
| KR102465358B1 (ko) * | 2021-11-05 | 2022-11-11 | 주식회사 엑티브온 | 마그놀올, 호노키올, 또는 이의 조합을 포함하는 피부 외용제용 보존제 및 이를 포함하는 화장료 조성물 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR0176015B1 (ko) | 1996-03-26 | 1999-03-20 | 서치영 | 치주질환 예방 및 치료제 조성물 |
| WO2001082922A1 (en) * | 2000-04-27 | 2001-11-08 | The Procter & Gamble Company | Oral compositions comprising polyphenol herbal extracts |
| US6500409B1 (en) * | 2000-05-10 | 2002-12-31 | Colgate Palmolive Company | Synergistic antiplaque/antigingivitis oral composition |
| US6544409B2 (en) | 2001-05-16 | 2003-04-08 | Petroleo Brasileiro S.A. - Petrobras | Process for the catalytic oxidation of sulfur, nitrogen and unsaturated compounds from hydrocarbon streams |
| CN1147286C (zh) * | 2001-07-18 | 2004-04-28 | 广州美晨股份有限公司 | 一种中药牙膏 |
| US7347985B2 (en) * | 2002-06-25 | 2008-03-25 | Wm. Wrigley Jr. Company | Breath freshening and oral cleansing product with magnolia bark extract |
| US7632525B2 (en) * | 2002-06-25 | 2009-12-15 | Wm. Wrigley Jr. Company | Breath freshening and oral cleansing product with magnolia bark extract in combination with surface active agents |
| CN1662220A (zh) * | 2002-06-25 | 2005-08-31 | Wm.雷格利Jr.公司 | 含有肉桂醛的口气清新和口腔清洁产品 |
| US20060127329A1 (en) | 2004-12-10 | 2006-06-15 | Colgate-Palmolive Company | Tartar control oral care composition containing extract of magnolia |
| US8900644B2 (en) * | 2004-12-22 | 2014-12-02 | Colgate-Palmolive Company | Oral care compositions containing compounds from magnolia and hops extracts |
| US20060140885A1 (en) | 2004-12-29 | 2006-06-29 | Abdul Gaffar | Method of reducing oral tissue inflammation using magnolia extract |
| US8071077B2 (en) * | 2004-12-29 | 2011-12-06 | Colgate-Palmolive Company | Oral compositions containing biphenol antibacterial compounds |
| CN101132806A (zh) * | 2004-12-29 | 2008-02-27 | 高露洁-棕榄公司 | 使用木兰提取物减少口腔组织炎症的方法 |
| US7608741B2 (en) * | 2005-05-30 | 2009-10-27 | Korea Institute Of Oriental Medicine | Mass separation method of magnolol from Magnoliae cortex radix |
| WO2008006582A1 (en) * | 2006-07-14 | 2008-01-17 | Dsm Ip Assets B.V. | Compositions comprising magnolol or honokiol and other active agents for the treatment of inflammatory diseases |
| WO2009045952A1 (en) | 2007-10-01 | 2009-04-09 | Colgate-Palmolive Company | Oral compositions containing botanical extracts |
-
2011
- 2011-02-23 TW TW100105895A patent/TWI422382B/zh not_active IP Right Cessation
- 2011-02-24 AU AU2011220789A patent/AU2011220789B2/en not_active Ceased
- 2011-02-24 AR ARP110100555A patent/AR080294A1/es unknown
- 2011-02-24 SG SG2012055778A patent/SG183117A1/en unknown
- 2011-02-24 JP JP2012555134A patent/JP5665888B2/ja not_active Expired - Fee Related
- 2011-02-24 MX MX2012009139A patent/MX2012009139A/es active IP Right Grant
- 2011-02-24 RU RU2015114797/15A patent/RU2015114797A/ru not_active Application Discontinuation
- 2011-02-24 CN CN201180010909.XA patent/CN102762219B/zh not_active Expired - Fee Related
- 2011-02-24 PH PH1/2012/501620A patent/PH12012501620A1/en unknown
- 2011-02-24 US US13/575,671 patent/US9801940B2/en active Active
- 2011-02-24 BR BR112012019997A patent/BR112012019997A2/pt not_active IP Right Cessation
- 2011-02-24 CA CA2788423A patent/CA2788423A1/en not_active Abandoned
- 2011-02-24 RU RU2012140474/15A patent/RU2552322C2/ru not_active IP Right Cessation
- 2011-02-24 EP EP11706721.5A patent/EP2523676B1/en active Active
- 2011-02-24 WO PCT/US2011/026017 patent/WO2011106492A1/en not_active Ceased
-
2012
- 2012-08-03 CO CO12131457A patent/CO6592076A2/es not_active Application Discontinuation
- 2012-08-13 ZA ZA2012/06068A patent/ZA201206068B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PH12012501620A1 (en) | 2012-10-22 |
| RU2012140474A (ru) | 2014-03-27 |
| RU2015114797A (ru) | 2015-09-20 |
| ZA201206068B (en) | 2015-04-29 |
| US20120294812A1 (en) | 2012-11-22 |
| EP2523676B1 (en) | 2016-04-20 |
| BR112012019997A2 (pt) | 2019-09-24 |
| CN102762219B (zh) | 2016-05-04 |
| CO6592076A2 (es) | 2013-01-02 |
| CN102762219A (zh) | 2012-10-31 |
| TWI422382B (zh) | 2014-01-11 |
| AU2011220789A1 (en) | 2012-08-23 |
| SG183117A1 (en) | 2012-09-27 |
| WO2011106492A1 (en) | 2011-09-01 |
| US9801940B2 (en) | 2017-10-31 |
| RU2552322C2 (ru) | 2015-06-10 |
| EP2523676A1 (en) | 2012-11-21 |
| TW201204376A (en) | 2012-02-01 |
| JP5665888B2 (ja) | 2015-02-04 |
| JP2013520517A (ja) | 2013-06-06 |
| AU2011220789B2 (en) | 2013-07-18 |
| MX2012009139A (es) | 2012-09-21 |
| CA2788423A1 (en) | 2011-09-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |