AR079439A1 - Granulado de carnitina y metodos para su produccion - Google Patents
Granulado de carnitina y metodos para su produccionInfo
- Publication number
- AR079439A1 AR079439A1 ARP100104597A ARP100104597A AR079439A1 AR 079439 A1 AR079439 A1 AR 079439A1 AR P100104597 A ARP100104597 A AR P100104597A AR P100104597 A ARP100104597 A AR P100104597A AR 079439 A1 AR079439 A1 AR 079439A1
- Authority
- AR
- Argentina
- Prior art keywords
- carnitine
- weight
- vehicle
- granulate
- silica
- Prior art date
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 title abstract 8
- 229960004203 carnitine Drugs 0.000 title abstract 8
- 239000008187 granular material Substances 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 6
- 239000000377 silicon dioxide Substances 0.000 abstract 3
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/10—Securing foodstuffs on a non-edible supporting member
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Husbandry (AREA)
- Inorganic Chemistry (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Obesity (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Cosmetics (AREA)
- Fodder In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Reivindicacion 1: Un método para producir un granulado de carnitina, que comprende los siguientes pasos: (a) proveer una solucion acuosa que comprende al menos 65% (peso en peso) de carnitina; (b) proveer un vehículo particulado que comprende sílice, donde el vehículo tiene un tamano de partícula promedio mayor de 150 microm; y (c) mezclar la solucion acuosa y el vehículo, mediante lo cual se excluye un paso de secado. Reivindicacion 12: Un granulado de carnitina con un tamano de partícula promedio mayor de 150 microm, donde los gránulos consisten esencialmente en un vehículo de sílice recubierto con carnitina, donde el granulado comprende opcionalmente un agente antiaglomerante. Reivindicacion 13: El granulado de carnitina de reivindicacion 12, donde los gránulos de carnitina comprenden entre 30 y 95% (peso en peso) de vehículo de sílice y entre 70 y 5% (peso en peso) de carnitina, en base a la cantidad total de solidos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09015339A EP2335495A1 (en) | 2009-12-11 | 2009-12-11 | Carnitine granulate and methods for its production |
Publications (1)
Publication Number | Publication Date |
---|---|
AR079439A1 true AR079439A1 (es) | 2012-01-25 |
Family
ID=41691995
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP100104597A AR079439A1 (es) | 2009-12-11 | 2010-12-10 | Granulado de carnitina y metodos para su produccion |
Country Status (11)
Country | Link |
---|---|
US (2) | US8470382B2 (es) |
EP (2) | EP2335495A1 (es) |
JP (2) | JP5911806B2 (es) |
KR (1) | KR101761958B1 (es) |
CN (1) | CN102651974B (es) |
AR (1) | AR079439A1 (es) |
ES (1) | ES2579964T3 (es) |
HK (1) | HK1169280A1 (es) |
IN (1) | IN2012DN04941A (es) |
TW (1) | TWI469797B (es) |
WO (1) | WO2011069654A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL169678A (en) | 2005-07-14 | 2010-11-30 | Innova Sa | Sweetener compositions |
EP2335495A1 (en) * | 2009-12-11 | 2011-06-22 | Lonza Ltd. | Carnitine granulate and methods for its production |
RU2603915C2 (ru) * | 2011-07-08 | 2016-12-10 | ПУРАК Биокем БВ | Активная композиция для применения в кормовых продуктах |
JP5933383B2 (ja) * | 2012-07-26 | 2016-06-08 | ロート製薬株式会社 | 内服用固形製剤の吸湿性・流動性の改善方法、吸湿性・流動性が改善されてなる内服用固形製剤、及び該内服用固形製剤の製造法 |
US20160242439A1 (en) | 2014-04-04 | 2016-08-25 | Douxmatok Ltd | Method for producing sweetener compositions and sweetener compositions |
US10207004B2 (en) | 2014-04-04 | 2019-02-19 | Douxmatok Ltd | Method for producing sweetener compositions and sweetener compositions |
US10231476B2 (en) | 2014-04-04 | 2019-03-19 | Douxmatok Ltd | Sweetener compositions and foods, beverages, and consumable products made thereof |
WO2016018339A1 (en) * | 2014-07-31 | 2016-02-04 | Benemilk Oy | Coated feed compositions and methods of making and using thereof |
JP6100939B2 (ja) * | 2016-02-26 | 2017-03-22 | ロート製薬株式会社 | 内服用固形製剤の吸湿性・流動性の改善方法、吸湿性・流動性が改善されてなる内服用固形製剤、及び該内服用固形製剤の製造法 |
CN106901042A (zh) * | 2017-04-27 | 2017-06-30 | 上海美嘉饲料有限公司 | 一种提高种公猪精子活力的饲料添加剂 |
JP7235501B2 (ja) * | 2017-12-28 | 2023-03-08 | アリナミン製薬株式会社 | ビタミンb1類及びカルニチン類を含有する顆粒 |
WO2022258631A1 (en) * | 2021-06-07 | 2022-12-15 | Kaesler Nutrition Gmbh | Carnitine formulation |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5073376A (en) | 1989-12-22 | 1991-12-17 | Lonza Ltd. | Preparations containing l-carnitine |
JPH0812569A (ja) | 1994-06-24 | 1996-01-16 | Takeda Chem Ind Ltd | 塩化カルニチン吸着固形物 |
IT1305308B1 (it) | 1999-03-26 | 2001-05-04 | Biosint S P A | Granulato ad alto contenuto di l-carnitina o alcanoil-l-carnitina,particolarmente adatto alla produzione di compresse per compressione |
CN1706814A (zh) * | 1999-09-03 | 2005-12-14 | 希格马托健康科学股份公司 | 超细l-肉碱、其制备方法、含有它的组合物及其使用方法 |
AU2006265280B2 (en) * | 2005-07-05 | 2011-07-14 | Lonza Ag | Spray-drying process for producing a dry carnitine powder or granulate |
JP5069416B2 (ja) * | 2006-03-15 | 2012-11-07 | サントリーホールディングス株式会社 | 吸湿性の改善された飲食品用組成物 |
EP2335495A1 (en) * | 2009-12-11 | 2011-06-22 | Lonza Ltd. | Carnitine granulate and methods for its production |
-
2009
- 2009-12-11 EP EP09015339A patent/EP2335495A1/en not_active Ceased
-
2010
- 2010-12-09 WO PCT/EP2010/007479 patent/WO2011069654A1/en active Application Filing
- 2010-12-09 CN CN201080056055.4A patent/CN102651974B/zh active Active
- 2010-12-09 JP JP2012542397A patent/JP5911806B2/ja active Active
- 2010-12-09 KR KR1020127017960A patent/KR101761958B1/ko active IP Right Grant
- 2010-12-09 US US12/964,187 patent/US8470382B2/en active Active
- 2010-12-09 EP EP10790620.8A patent/EP2509436B1/en active Active
- 2010-12-09 ES ES10790620.8T patent/ES2579964T3/es active Active
- 2010-12-10 AR ARP100104597A patent/AR079439A1/es unknown
- 2010-12-10 TW TW99143177A patent/TWI469797B/zh active
-
2012
- 2012-06-05 IN IN4941DEN2012 patent/IN2012DN04941A/en unknown
- 2012-10-12 HK HK12110094.0A patent/HK1169280A1/xx not_active IP Right Cessation
-
2013
- 2013-06-03 US US13/908,645 patent/US9066868B2/en active Active
-
2015
- 2015-12-25 JP JP2015254564A patent/JP6239579B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
JP6239579B2 (ja) | 2017-11-29 |
US20130273165A1 (en) | 2013-10-17 |
KR20120104315A (ko) | 2012-09-20 |
ES2579964T3 (es) | 2016-08-17 |
TWI469797B (zh) | 2015-01-21 |
US9066868B2 (en) | 2015-06-30 |
IN2012DN04941A (es) | 2015-09-25 |
TW201127407A (en) | 2011-08-16 |
EP2509436B1 (en) | 2016-04-06 |
JP2016117736A (ja) | 2016-06-30 |
US20110190394A1 (en) | 2011-08-04 |
EP2335495A1 (en) | 2011-06-22 |
JP2013513557A (ja) | 2013-04-22 |
CN102651974A (zh) | 2012-08-29 |
HK1169280A1 (en) | 2013-01-25 |
EP2509436A1 (en) | 2012-10-17 |
KR101761958B1 (ko) | 2017-07-26 |
JP5911806B2 (ja) | 2016-04-27 |
CN102651974B (zh) | 2015-04-01 |
WO2011069654A1 (en) | 2011-06-16 |
US8470382B2 (en) | 2013-06-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |