AR077858A1 - Uso de la 4-aminopiridina para mejorar el deterioro cognitivo en pacientes con desmielinizacion y otros estados del sistema nervioso - Google Patents

Uso de la 4-aminopiridina para mejorar el deterioro cognitivo en pacientes con desmielinizacion y otros estados del sistema nervioso

Info

Publication number
AR077858A1
AR077858A1 ARP100102953A ARP100102953A AR077858A1 AR 077858 A1 AR077858 A1 AR 077858A1 AR P100102953 A ARP100102953 A AR P100102953A AR P100102953 A ARP100102953 A AR P100102953A AR 077858 A1 AR077858 A1 AR 077858A1
Authority
AR
Argentina
Prior art keywords
patients
demielinization
aminopiridine
states
nervous system
Prior art date
Application number
ARP100102953A
Other languages
English (en)
Inventor
Andrew Blight
Thomas C Wessel
Original Assignee
Acorda Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acorda Therapeutics Inc filed Critical Acorda Therapeutics Inc
Publication of AR077858A1 publication Critical patent/AR077858A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

En este documento se describen métodos y composiciones relacionados con el uso de aminopiridinas, tales como la fampridina, para mejorar el deterioro neurocognitivo o neuropsiquiátrico en pacientes con enfermedades desmielinizantes, tales como esclerosis multiple, lesion cerebral traumática, parálisis cerebral o encefalopatía posterior a radiacion. Reivindicacion 7: el método referido en la rreivindicacion 6 caracterizado porque la Famprimidina-SR se dosifica a 10 mg dos veces al día.
ARP100102953A 2009-08-11 2010-08-11 Uso de la 4-aminopiridina para mejorar el deterioro cognitivo en pacientes con desmielinizacion y otros estados del sistema nervioso AR077858A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23307709P 2009-08-11 2009-08-11
US23306909P 2009-08-11 2009-08-11
US23987709P 2009-09-04 2009-09-04

Publications (1)

Publication Number Publication Date
AR077858A1 true AR077858A1 (es) 2011-09-28

Family

ID=43586462

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100102953A AR077858A1 (es) 2009-08-11 2010-08-11 Uso de la 4-aminopiridina para mejorar el deterioro cognitivo en pacientes con desmielinizacion y otros estados del sistema nervioso

Country Status (18)

Country Link
US (8) US20130053420A1 (es)
EP (1) EP2464229B1 (es)
JP (2) JP6137833B2 (es)
KR (2) KR20120050473A (es)
CN (1) CN102143687B (es)
AR (1) AR077858A1 (es)
AU (1) AU2010282509B2 (es)
BR (1) BRPI1003991A2 (es)
CA (1) CA2770698C (es)
ES (1) ES2563751T3 (es)
HK (1) HK1173911A1 (es)
JO (1) JO3348B1 (es)
MX (1) MX2012001814A (es)
RU (1) RU2563821C2 (es)
TW (2) TWI549678B (es)
UY (1) UY32837A (es)
WO (1) WO2011019845A1 (es)
ZA (1) ZA201201001B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8007826B2 (en) 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions
US20130184316A1 (en) * 2010-07-15 2013-07-18 Andrew Hornstein Methods for diagnosing and treating concussive disorders
EP2995305B1 (en) * 2011-01-28 2020-03-04 Acorda Therapeutics, Inc. Use of potassium channel blockers to treat cerebral palsy
US10793893B2 (en) 2011-06-30 2020-10-06 Serb Sa Methods of administering 3,4-diaminopyridine
WO2014138298A1 (en) * 2013-03-05 2014-09-12 University Of Chicago Treatment of demyelinating disorders
EP3427735A1 (en) * 2013-04-15 2019-01-16 Acorda Therapeutics, Inc. Methods for treating sensorimotor impairments associated with certain types of stroke using aminopyridines
DE102014221687B4 (de) * 2014-10-24 2019-07-04 Danfoss Silicon Power Gmbh Leistungshalbleitermodul mit kurzschluss-ausfallmodus
DE102017115701B4 (de) * 2017-07-12 2022-03-03 Lts Lohmann Therapie-Systeme Ag Fampridin-TTS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE82916B1 (en) * 1990-11-02 2003-06-11 Elan Corp Plc Formulations and their use in the treatment of neurological diseases
US5977131A (en) 1997-04-09 1999-11-02 Pfizer Inc. Azaindole-ethylamine derivatives as nicotinic acetylcholine receptor binding agents
AU2002250307A1 (en) * 2001-03-14 2002-09-24 The Government Of The United States Of America, As Represented By The Secretary Of Health And Human Improving postsynaptic response by a combination of 4-minopyridine and agonist
US8007826B2 (en) * 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) * 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions

Also Published As

Publication number Publication date
TW201613585A (en) 2016-04-16
ES2563751T3 (es) 2016-03-16
US20190247379A1 (en) 2019-08-15
RU2563821C2 (ru) 2015-09-20
WO2011019845A1 (en) 2011-02-17
TWI549678B (zh) 2016-09-21
EP2464229B1 (en) 2015-11-25
US20160213661A1 (en) 2016-07-28
US20190015399A1 (en) 2019-01-17
JP2016074728A (ja) 2016-05-12
BRPI1003991A2 (pt) 2015-09-15
ZA201201001B (en) 2014-10-29
KR20120050473A (ko) 2012-05-18
RU2012108656A (ru) 2013-09-20
UY32837A (es) 2011-03-31
JP2013501805A (ja) 2013-01-17
AU2010282509B2 (en) 2015-07-30
US20170056385A1 (en) 2017-03-02
JO3348B1 (ar) 2019-03-13
CA2770698C (en) 2018-01-30
KR20170128633A (ko) 2017-11-22
CN102143687B (zh) 2015-11-25
US20170281608A1 (en) 2017-10-05
MX2012001814A (es) 2012-06-01
US20130053420A1 (en) 2013-02-28
TW201110967A (en) 2011-04-01
US20200113882A1 (en) 2020-04-16
EP2464229A4 (en) 2013-02-13
CA2770698A1 (en) 2011-02-17
AU2010282509A1 (en) 2012-03-01
EP2464229A1 (en) 2012-06-20
CN102143687A (zh) 2011-08-03
US20180147193A1 (en) 2018-05-31
HK1173911A1 (zh) 2013-05-31
JP6137833B2 (ja) 2017-05-31

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