AR069311A1 - Proceso para preparar (r)-5-(2-aminoetil)-1-(6,8-difluorocroman-3-il)-1,3-dihidroimidazol-2-tiona y compuestos intermediarios de sintesis - Google Patents
Proceso para preparar (r)-5-(2-aminoetil)-1-(6,8-difluorocroman-3-il)-1,3-dihidroimidazol-2-tiona y compuestos intermediarios de sintesisInfo
- Publication number
- AR069311A1 AR069311A1 ARP080104958A ARP080104958A AR069311A1 AR 069311 A1 AR069311 A1 AR 069311A1 AR P080104958 A ARP080104958 A AR P080104958A AR P080104958 A ARP080104958 A AR P080104958A AR 069311 A1 AR069311 A1 AR 069311A1
- Authority
- AR
- Argentina
- Prior art keywords
- compound
- formula
- halogen
- term
- alkyl
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 10
- 238000000034 method Methods 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 229910052736 halogen Inorganic materials 0.000 abstract 8
- 150000002367 halogens Chemical class 0.000 abstract 8
- 125000003545 alkoxy group Chemical group 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000003118 aryl group Chemical group 0.000 abstract 5
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 4
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 125000003282 alkyl amino group Chemical group 0.000 abstract 2
- 125000003806 alkyl carbonyl amino group Chemical group 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 229910052740 iodine Inorganic materials 0.000 abstract 2
- 239000011630 iodine Substances 0.000 abstract 2
- 125000001624 naphthyl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- NAWXUBYGYWOOIX-SFHVURJKSA-N (2s)-2-[[4-[2-(2,4-diaminoquinazolin-6-yl)ethyl]benzoyl]amino]-4-methylidenepentanedioic acid Chemical compound C1=CC2=NC(N)=NC(N)=C2C=C1CCC1=CC=C(C(=O)N[C@@H](CC(=C)C(O)=O)C(O)=O)C=C1 NAWXUBYGYWOOIX-SFHVURJKSA-N 0.000 abstract 1
- 229940126214 compound 3 Drugs 0.000 abstract 1
- 229940125898 compound 5 Drugs 0.000 abstract 1
- ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical group O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 1
- -1 hydroxycarbonyl groups Chemical group 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98746707P | 2007-11-13 | 2007-11-13 | |
| US8592708P | 2008-08-04 | 2008-08-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR069311A1 true AR069311A1 (es) | 2010-01-13 |
Family
ID=40550012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080104958A AR069311A1 (es) | 2007-11-13 | 2008-11-13 | Proceso para preparar (r)-5-(2-aminoetil)-1-(6,8-difluorocroman-3-il)-1,3-dihidroimidazol-2-tiona y compuestos intermediarios de sintesis |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20100298580A1 (OSRAM) |
| EP (1) | EP2217585A2 (OSRAM) |
| JP (1) | JP2011503175A (OSRAM) |
| KR (1) | KR20100102606A (OSRAM) |
| CN (1) | CN101952271A (OSRAM) |
| AR (1) | AR069311A1 (OSRAM) |
| AU (1) | AU2008321625A1 (OSRAM) |
| BR (1) | BRPI0818105A2 (OSRAM) |
| CA (1) | CA2705512A1 (OSRAM) |
| MX (1) | MX2010005193A (OSRAM) |
| RU (1) | RU2010123778A (OSRAM) |
| TW (1) | TW200927740A (OSRAM) |
| WO (1) | WO2009064210A2 (OSRAM) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201316410D0 (en) | 2013-09-13 | 2013-10-30 | Bial Portela & Ca Sa | Processes for preparing peripherally-selective inhibitors of dopamine-?-hydroxylase and intermediates for use therein |
| US11875700B2 (en) | 2014-05-20 | 2024-01-16 | Jessica Robinson | Systems and methods for providing communication services |
| CN110590728B (zh) * | 2019-10-15 | 2022-03-22 | 青岛科技大学 | 一种多取代4-苯基色满类化合物的合成方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0232279B2 (ja) * | 1982-08-12 | 1990-07-19 | Kowa Co | Jihidorobenzopiranjioorunoseiho |
| SE8605504D0 (sv) * | 1986-12-19 | 1986-12-19 | Astra Laekemedel Ab | Novel chroman derivatives |
| BR9507517A (pt) * | 1994-04-26 | 1997-09-16 | Syntex Inc | Derivados de benzocicloalquilazotetiona |
| US6867224B2 (en) * | 2002-03-07 | 2005-03-15 | Warner-Lambert Company | Compounds that modulate PPAR activity and methods of preparation |
| JP2004075614A (ja) * | 2002-08-20 | 2004-03-11 | Sankyo Co Ltd | クロメン誘導体を含有する医薬 |
| US7125904B2 (en) * | 2002-10-11 | 2006-10-24 | Portela & C.A., S.A. | Peripherally-selective inhibitors of dopamine-β-hydroxylase and method of their preparation |
| US20050032873A1 (en) * | 2003-07-30 | 2005-02-10 | Wyeth | 3-Amino chroman and 2-amino tetralin derivatives |
| US7456214B2 (en) * | 2004-05-03 | 2008-11-25 | Baylor University | Chromene-containing compounds with anti-tubulin and vascular targeting activity |
| US20050245489A1 (en) * | 2004-05-03 | 2005-11-03 | Pinney Kevin G | Chromene-containing compounds with anti-tubulin and vascular targeting activity |
| BRPI0512623A (pt) * | 2004-06-25 | 2008-03-25 | Janssen Phamaceutica N V | sal quaternário antagonista de ccr2 |
| JP5193602B2 (ja) * | 2004-10-14 | 2013-05-08 | アボット ゲーエムベーハー ウント カンパニー カーゲー | ドーパミンｄ３受容体の調節に応答する障害の治療に好適なアリールスルホニルメチルまたはアリールスルホンアミド置換芳香族化合物 |
| KR20080074220A (ko) * | 2005-12-08 | 2008-08-12 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | 키나아제 억제 활성을 갖는 비시클릭 화합물 |
| RU2009126571A (ru) * | 2006-12-12 | 2011-01-20 | Биал-Портела Энд Ка, С.А. (Pt) | Каталитический способ асимметричной гидрогенизации |
-
2008
- 2008-11-12 TW TW097143774A patent/TW200927740A/zh unknown
- 2008-11-13 US US12/742,738 patent/US20100298580A1/en not_active Abandoned
- 2008-11-13 AR ARP080104958A patent/AR069311A1/es unknown
- 2008-11-13 MX MX2010005193A patent/MX2010005193A/es not_active Application Discontinuation
- 2008-11-13 AU AU2008321625A patent/AU2008321625A1/en not_active Abandoned
- 2008-11-13 JP JP2010533987A patent/JP2011503175A/ja active Pending
- 2008-11-13 RU RU2010123778/04A patent/RU2010123778A/ru unknown
- 2008-11-13 CN CN2008801246552A patent/CN101952271A/zh active Pending
- 2008-11-13 EP EP08850447A patent/EP2217585A2/en not_active Withdrawn
- 2008-11-13 BR BRPI0818105A patent/BRPI0818105A2/pt not_active IP Right Cessation
- 2008-11-13 WO PCT/PT2008/000048 patent/WO2009064210A2/en not_active Ceased
- 2008-11-13 KR KR1020107012805A patent/KR20100102606A/ko not_active Withdrawn
- 2008-11-13 CA CA2705512A patent/CA2705512A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011503175A (ja) | 2011-01-27 |
| MX2010005193A (es) | 2010-06-02 |
| WO2009064210A2 (en) | 2009-05-22 |
| CA2705512A1 (en) | 2009-05-22 |
| EP2217585A2 (en) | 2010-08-18 |
| BRPI0818105A2 (pt) | 2019-09-24 |
| TW200927740A (en) | 2009-07-01 |
| CN101952271A (zh) | 2011-01-19 |
| KR20100102606A (ko) | 2010-09-24 |
| RU2010123778A (ru) | 2011-12-20 |
| AU2008321625A1 (en) | 2009-05-22 |
| US20100298580A1 (en) | 2010-11-25 |
| WO2009064210A3 (en) | 2009-12-30 |
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Legal Events
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| FB | Suspension of granting procedure |