AR067322A1 - Vector poxvirus recombinante de mapache (rrcnv) vacuna felina, plasmido y metodos para inducir una respuesta inmune protectora a un patogeno de felino en un gato - Google Patents
Vector poxvirus recombinante de mapache (rrcnv) vacuna felina, plasmido y metodos para inducir una respuesta inmune protectora a un patogeno de felino en un gatoInfo
- Publication number
- AR067322A1 AR067322A1 ARP080102317A ARP080102317A AR067322A1 AR 067322 A1 AR067322 A1 AR 067322A1 AR P080102317 A ARP080102317 A AR P080102317A AR P080102317 A ARP080102317 A AR P080102317A AR 067322 A1 AR067322 A1 AR 067322A1
- Authority
- AR
- Argentina
- Prior art keywords
- feline
- cat
- recombinant poxvirus
- recombinant
- mapache
- Prior art date
Links
- 241000282324 Felis Species 0.000 title abstract 6
- 244000052769 pathogen Species 0.000 title abstract 3
- 239000013598 vector Substances 0.000 title abstract 3
- 230000001681 protective effect Effects 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 230000001717 pathogenic effect Effects 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 241000282326 Felis catus Species 0.000 abstract 2
- 101710154606 Hemagglutinin Proteins 0.000 abstract 2
- 101710093908 Outer capsid protein VP4 Proteins 0.000 abstract 2
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 abstract 2
- 241000282330 Procyon lotor Species 0.000 abstract 2
- 101710176177 Protein A56 Proteins 0.000 abstract 2
- 102000006601 Thymidine Kinase Human genes 0.000 abstract 2
- 108020004440 Thymidine kinase Proteins 0.000 abstract 2
- 239000000185 hemagglutinin Substances 0.000 abstract 2
- 108010008038 Synthetic Vaccines Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 229940031348 multivalent vaccine Drugs 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 229940124551 recombinant vaccine Drugs 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/863—Poxviral vectors, e.g. entomopoxvirus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/16011—Caliciviridae
- C12N2770/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Vectores de poxvirus recombinantes de mapache que comprenden dos o más moléculas de ácido nucleico exogenas, que codifica cada una por lo menos una proteína de felino, en donde por lo menos dos de las moléculas de ácido nucleico se insertan en el sitio de hemaglutinina (ha) o el sitio de timidina quinasa (tk), o por lo menos una de las moléculas de ácido nucleico se inserta en cada uno de los sitios de hemaglutinina y timidina quinasa. Las vacunas recombinantes de felino, monovalentes y polivalentes comprenden una cantidad inmunologicamente efectiva de los vectores de poxvirus recombinantes de mapache y. opcionalmente, un vehículo o diluyente adecuado. La vacuna incluye opcionalmente antígenos de felino adicionales para suministrar proteccion de amplio espectro a gatos contra una variedad de patogenos de felino. Se induce una respuesta inmune protectora a los patogenos de felino en un gato al administrar las vacunas recombinantes.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US93241907P | 2007-05-30 | 2007-05-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR067322A1 true AR067322A1 (es) | 2009-10-07 |
Family
ID=39701101
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP080102317A AR067322A1 (es) | 2007-05-30 | 2008-06-02 | Vector poxvirus recombinante de mapache (rrcnv) vacuna felina, plasmido y metodos para inducir una respuesta inmune protectora a un patogeno de felino en un gato |
Country Status (13)
Country | Link |
---|---|
US (1) | US20080299149A1 (es) |
EP (1) | EP2155883A1 (es) |
JP (1) | JP2010528603A (es) |
KR (1) | KR20100038323A (es) |
CN (1) | CN101849013A (es) |
AR (1) | AR067322A1 (es) |
AU (1) | AU2008260593A1 (es) |
CA (1) | CA2681183A1 (es) |
CL (1) | CL2008001558A1 (es) |
CO (1) | CO6241172A2 (es) |
MX (1) | MX2009013030A (es) |
WO (1) | WO2008150404A1 (es) |
ZA (1) | ZA200908963B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX344103B (es) * | 2010-08-31 | 2016-12-05 | Merial Ltd | Vacunas de virus herpes vectorizado con virus de enfermedad de newcastle. |
SI2734230T1 (sl) | 2011-07-20 | 2019-04-30 | Merial Limited | Rekombinantno cepivo proti virusu mačje levkemije, ki vsebuje optimiziran gen ovojnice virusa mačje levkemije |
US11229699B2 (en) * | 2017-11-06 | 2022-01-25 | Intervet Inc. | Feline calicivirus vaccine |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3944469A (en) * | 1974-11-21 | 1976-03-16 | Pitman-Moore, Inc. | Feline calicivirus vaccine and production thereof |
US4264587A (en) * | 1979-08-01 | 1981-04-28 | Pedersen Niels C | Vaccine for preventing persistent feline leukemia viremia in cats |
US5505941A (en) * | 1981-12-24 | 1996-04-09 | Health Research, Inc. | Recombinant avipox virus and method to induce an immune response |
US5106619A (en) * | 1983-12-20 | 1992-04-21 | Diamond Scientific Co. | Preparation of inactivated viral vaccines |
US5374424A (en) * | 1986-10-03 | 1994-12-20 | Miles Inc. | Multivalent felv-infected feline vaccine |
US5242686A (en) * | 1990-11-07 | 1993-09-07 | American Home Products Corporation | Feline vaccine compositions and method for preventing chlamydia infections or diseases using the same |
US6004563A (en) * | 1990-11-07 | 1999-12-21 | American Home Products Corporation | Feline vaccine compositions and method for preventing chlamydia infections or diseases using the same |
US6241989B1 (en) * | 1991-07-09 | 2001-06-05 | Cornell Research Foundation, Inc. | Recombinant multivalent viral vaccine |
US7087234B1 (en) * | 1991-07-09 | 2006-08-08 | Cornell Research Foundation, Inc. | Recombinant multivalent viral vaccine |
US6010703A (en) * | 1993-07-26 | 2000-01-04 | Board Of Trustees Operating Michigan State University | Recombinant poxvirus vaccine against feline rhinotracheitis |
TW377373B (en) * | 1993-09-22 | 1999-12-21 | Wyeth Corp | Recombinant raccoon pox viruses and their use as an effective vaccine against feline infectious peritonitis virus disease |
US5820869A (en) * | 1995-06-07 | 1998-10-13 | American Home Products Corporation | Recombinant raccoon pox viruses and their use as an effective vaccine against feline immunodeficiency virus infection |
US5972350A (en) * | 1996-05-06 | 1999-10-26 | Bayer Corporation | Feline vaccines containing Chlamydia psittaci and method for making the same |
JP4000608B2 (ja) * | 1996-11-07 | 2007-10-31 | トヨタ自動車株式会社 | 水素製造充填装置および電気自動車 |
US6231863B1 (en) * | 1997-06-10 | 2001-05-15 | American Cyanamid Company | DNA sequences, molecules, vectors and vaccines for feline calicivirus disease and methods for producing and using same |
US6051239A (en) * | 1997-10-20 | 2000-04-18 | Thomas Jefferson University | Compositions and methods for systemic delivery of oral vaccines and therapeutic agents |
US6106841A (en) * | 1998-02-04 | 2000-08-22 | Heska Corporation | Delivery method for recombinant raccoon poxvirus |
US6534066B1 (en) * | 1999-07-16 | 2003-03-18 | Merial | Inactivated vaccine against feline calicivirosis |
US6541458B1 (en) * | 1999-07-16 | 2003-04-01 | Merial | Feline calicivirus genes and vaccines in particular recombinant vaccines |
AU2003236646B2 (en) * | 2002-05-16 | 2009-01-15 | Bavarian Nordic A/S | Recombinant poxvirus expressing homologous genes inserted into the poxviral genome |
US7309495B2 (en) * | 2003-03-14 | 2007-12-18 | The Regents Of The University Of California | Hemorrhagic feline calicivirus |
US7306807B2 (en) * | 2004-09-13 | 2007-12-11 | Wyeth | Hemorrhagic feline calicivirus, calicivirus vaccine and method for preventing calicivirus infection or disease |
-
2008
- 2008-05-28 CA CA002681183A patent/CA2681183A1/en not_active Abandoned
- 2008-05-28 MX MX2009013030A patent/MX2009013030A/es active IP Right Grant
- 2008-05-28 EP EP08767900A patent/EP2155883A1/en not_active Withdrawn
- 2008-05-28 WO PCT/US2008/006732 patent/WO2008150404A1/en active Application Filing
- 2008-05-28 US US12/128,329 patent/US20080299149A1/en not_active Abandoned
- 2008-05-28 KR KR1020097027364A patent/KR20100038323A/ko not_active Application Discontinuation
- 2008-05-28 AU AU2008260593A patent/AU2008260593A1/en not_active Abandoned
- 2008-05-28 JP JP2010510314A patent/JP2010528603A/ja active Pending
- 2008-05-28 CN CN200880022595A patent/CN101849013A/zh active Pending
- 2008-05-29 CL CL200801558A patent/CL2008001558A1/es unknown
- 2008-06-02 AR ARP080102317A patent/AR067322A1/es not_active Application Discontinuation
-
2009
- 2009-11-30 CO CO09136415A patent/CO6241172A2/es not_active Application Discontinuation
- 2009-12-15 ZA ZA200908963A patent/ZA200908963B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP2155883A1 (en) | 2010-02-24 |
JP2010528603A (ja) | 2010-08-26 |
WO2008150404A1 (en) | 2008-12-11 |
KR20100038323A (ko) | 2010-04-14 |
MX2009013030A (es) | 2010-03-25 |
AU2008260593A1 (en) | 2008-12-11 |
US20080299149A1 (en) | 2008-12-04 |
ZA200908963B (en) | 2010-08-25 |
CA2681183A1 (en) | 2008-12-11 |
CO6241172A2 (es) | 2011-01-20 |
CN101849013A (zh) | 2010-09-29 |
CL2008001558A1 (es) | 2008-07-25 |
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Legal Events
Date | Code | Title | Description |
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FA | Abandonment or withdrawal |