AR066812A1 - Vector poxvirus recombinante de mapache (rrcnv) vacuna recombinante porcina y metodos para inducir un respuesta inmune contra el virus del sindrome reproductivo y respiratorio de porcinos y para prevenir el sindrome reproductivo y respiratorio de porcino y el sindrome de desmedro multisistemico post - Google Patents
Vector poxvirus recombinante de mapache (rrcnv) vacuna recombinante porcina y metodos para inducir un respuesta inmune contra el virus del sindrome reproductivo y respiratorio de porcinos y para prevenir el sindrome reproductivo y respiratorio de porcino y el sindrome de desmedro multisistemico postInfo
- Publication number
- AR066812A1 AR066812A1 ARP080102315A ARP080102315A AR066812A1 AR 066812 A1 AR066812 A1 AR 066812A1 AR P080102315 A ARP080102315 A AR P080102315A AR P080102315 A ARP080102315 A AR P080102315A AR 066812 A1 AR066812 A1 AR 066812A1
- Authority
- AR
- Argentina
- Prior art keywords
- reproductive
- recombinant
- respiratory syndrome
- syrdrometrical
- mapache
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title abstract 2
- 230000001850 reproductive effect Effects 0.000 title 2
- 241000282898 Sus scrofa Species 0.000 title 1
- 108010008038 Synthetic Vaccines Proteins 0.000 title 1
- 230000028993 immune response Effects 0.000 title 1
- 229940124551 recombinant vaccine Drugs 0.000 title 1
- 230000000241 respiratory effect Effects 0.000 title 1
- 208000011580 syndromic disease Diseases 0.000 title 1
- 108700026244 Open Reading Frames Proteins 0.000 abstract 2
- 241001673669 Porcine circovirus 2 Species 0.000 abstract 2
- 101000621943 Acholeplasma phage L2 Probable integrase/recombinase Proteins 0.000 abstract 1
- 101000768957 Acholeplasma phage L2 Uncharacterized 37.2 kDa protein Proteins 0.000 abstract 1
- 101000823746 Acidianus ambivalens Uncharacterized 17.7 kDa protein in bps2 3'region Proteins 0.000 abstract 1
- 101000916369 Acidianus ambivalens Uncharacterized protein in sor 5'region Proteins 0.000 abstract 1
- 101000769342 Acinetobacter guillouiae Uncharacterized protein in rpoN-murA intergenic region Proteins 0.000 abstract 1
- 101000823696 Actinobacillus pleuropneumoniae Uncharacterized glycosyltransferase in aroQ 3'region Proteins 0.000 abstract 1
- 101000786513 Agrobacterium tumefaciens (strain 15955) Uncharacterized protein outside the virF region Proteins 0.000 abstract 1
- 101000618005 Alkalihalobacillus pseudofirmus (strain ATCC BAA-2126 / JCM 17055 / OF4) Uncharacterized protein BpOF4_00885 Proteins 0.000 abstract 1
- 101000618348 Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D) Uncharacterized protein Alvin_0065 Proteins 0.000 abstract 1
- 102100020724 Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 Human genes 0.000 abstract 1
- 101000781117 Autographa californica nuclear polyhedrosis virus Uncharacterized 12.4 kDa protein in CTL-LEF2 intergenic region Proteins 0.000 abstract 1
- 101000967489 Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571) Uncharacterized protein AZC_3924 Proteins 0.000 abstract 1
- 101000708323 Azospirillum brasilense Uncharacterized 28.8 kDa protein in nifR3-like 5'region Proteins 0.000 abstract 1
- 101000770311 Azotobacter chroococcum mcd 1 Uncharacterized 19.8 kDa protein in nifW 5'region Proteins 0.000 abstract 1
- 101000823761 Bacillus licheniformis Uncharacterized 9.4 kDa protein in flaL 3'region Proteins 0.000 abstract 1
- 101000819719 Bacillus methanolicus Uncharacterized N-acetyltransferase in lysA 3'region Proteins 0.000 abstract 1
- 101000789586 Bacillus subtilis (strain 168) UPF0702 transmembrane protein YkjA Proteins 0.000 abstract 1
- 101000748761 Bacillus subtilis (strain 168) Uncharacterized MFS-type transporter YcxA Proteins 0.000 abstract 1
- 101000792624 Bacillus subtilis (strain 168) Uncharacterized protein YbxH Proteins 0.000 abstract 1
- 101000790792 Bacillus subtilis (strain 168) Uncharacterized protein YckC Proteins 0.000 abstract 1
- 101000765620 Bacillus subtilis (strain 168) Uncharacterized protein YlxP Proteins 0.000 abstract 1
- 101000819705 Bacillus subtilis (strain 168) Uncharacterized protein YlxR Proteins 0.000 abstract 1
- 101000916134 Bacillus subtilis (strain 168) Uncharacterized protein YqxJ Proteins 0.000 abstract 1
- 101000948218 Bacillus subtilis (strain 168) Uncharacterized protein YtxJ Proteins 0.000 abstract 1
- 101000718627 Bacillus thuringiensis subsp. kurstaki Putative RNA polymerase sigma-G factor Proteins 0.000 abstract 1
- 101000641200 Bombyx mori densovirus Putative non-structural protein Proteins 0.000 abstract 1
- 101000754349 Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) UPF0065 protein BP0148 Proteins 0.000 abstract 1
- 101000827633 Caldicellulosiruptor sp. (strain Rt8B.4) Uncharacterized 23.9 kDa protein in xynA 3'region Proteins 0.000 abstract 1
- 101000947628 Claviceps purpurea Uncharacterized 11.8 kDa protein Proteins 0.000 abstract 1
- 101000947633 Claviceps purpurea Uncharacterized 13.8 kDa protein Proteins 0.000 abstract 1
- 101000686796 Clostridium perfringens Replication protein Proteins 0.000 abstract 1
- 102100031725 Cortactin-binding protein 2 Human genes 0.000 abstract 1
- 101000948901 Enterobacteria phage T4 Uncharacterized 16.0 kDa protein in segB-ipI intergenic region Proteins 0.000 abstract 1
- 101000805958 Equine herpesvirus 4 (strain 1942) Virion protein US10 homolog Proteins 0.000 abstract 1
- 101000790442 Escherichia coli Insertion element IS2 uncharacterized 11.1 kDa protein Proteins 0.000 abstract 1
- 101000788129 Escherichia coli Uncharacterized protein in sul1 3'region Proteins 0.000 abstract 1
- 101000788370 Escherichia phage P2 Uncharacterized 12.9 kDa protein in GpA 3'region Proteins 0.000 abstract 1
- 101000788354 Escherichia phage P2 Uncharacterized 8.2 kDa protein in gpA 5'region Proteins 0.000 abstract 1
- 101000770304 Frankia alni UPF0460 protein in nifX-nifW intergenic region Proteins 0.000 abstract 1
- 101000797344 Geobacillus stearothermophilus Putative tRNA (cytidine(34)-2'-O)-methyltransferase Proteins 0.000 abstract 1
- 101000748410 Geobacillus stearothermophilus Uncharacterized protein in fumA 3'region Proteins 0.000 abstract 1
- 101000787096 Geobacillus stearothermophilus Uncharacterized protein in gldA 3'region Proteins 0.000 abstract 1
- 101000772675 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) UPF0438 protein HI_0847 Proteins 0.000 abstract 1
- 101000631019 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) Uncharacterized protein HI_0350 Proteins 0.000 abstract 1
- 101000976889 Haemophilus phage HP1 (strain HP1c1) Uncharacterized 19.2 kDa protein in cox-rep intergenic region Proteins 0.000 abstract 1
- 101000768938 Haemophilus phage HP1 (strain HP1c1) Uncharacterized 8.9 kDa protein in int-C1 intergenic region Proteins 0.000 abstract 1
- 101710154606 Hemagglutinin Proteins 0.000 abstract 1
- 101000785414 Homo sapiens Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 Proteins 0.000 abstract 1
- 101000782488 Junonia coenia densovirus (isolate pBRJ/1990) Putative non-structural protein NS2 Proteins 0.000 abstract 1
- 101000827627 Klebsiella pneumoniae Putative low molecular weight protein-tyrosine-phosphatase Proteins 0.000 abstract 1
- 101000811523 Klebsiella pneumoniae Uncharacterized 55.8 kDa protein in cps region Proteins 0.000 abstract 1
- 101000818409 Lactococcus lactis subsp. lactis Uncharacterized HTH-type transcriptional regulator in lacX 3'region Proteins 0.000 abstract 1
- 101000878851 Leptolyngbya boryana Putative Fe(2+) transport protein A Proteins 0.000 abstract 1
- 101000758828 Methanosarcina barkeri (strain Fusaro / DSM 804) Uncharacterized protein Mbar_A1602 Proteins 0.000 abstract 1
- 101001122401 Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) Non-structural protein ORF3 Proteins 0.000 abstract 1
- 101001130841 Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) Non-structural protein ORF5 Proteins 0.000 abstract 1
- 101001055788 Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) Pentapeptide repeat protein MfpA Proteins 0.000 abstract 1
- 101710087110 ORF6 protein Proteins 0.000 abstract 1
- 101000740670 Orgyia pseudotsugata multicapsid polyhedrosis virus Protein C42 Proteins 0.000 abstract 1
- 101710093908 Outer capsid protein VP4 Proteins 0.000 abstract 1
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 abstract 1
- 101000769182 Photorhabdus luminescens Uncharacterized protein in pnp 3'region Proteins 0.000 abstract 1
- 101710159752 Poly(3-hydroxyalkanoate) polymerase subunit PhaE Proteins 0.000 abstract 1
- 208000005342 Porcine Reproductive and Respiratory Syndrome Diseases 0.000 abstract 1
- 101710130262 Probable Vpr-like protein Proteins 0.000 abstract 1
- 101710197985 Probable protein Rev Proteins 0.000 abstract 1
- 241000282330 Procyon lotor Species 0.000 abstract 1
- 101710176177 Protein A56 Proteins 0.000 abstract 1
- 101000961392 Pseudescherichia vulneris Uncharacterized 29.9 kDa protein in crtE 3'region Proteins 0.000 abstract 1
- 101000731030 Pseudomonas oleovorans Poly(3-hydroxyalkanoate) polymerase 2 Proteins 0.000 abstract 1
- 101001065485 Pseudomonas putida Probable fatty acid methyltransferase Proteins 0.000 abstract 1
- 101000711023 Rhizobium leguminosarum bv. trifolii Uncharacterized protein in tfuA 3'region Proteins 0.000 abstract 1
- 101000974028 Rhizobium leguminosarum bv. viciae (strain 3841) Putative cystathionine beta-lyase Proteins 0.000 abstract 1
- 101000756519 Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) Uncharacterized protein RCAP_rcc00048 Proteins 0.000 abstract 1
- 101000948219 Rhodococcus erythropolis Uncharacterized 11.5 kDa protein in thcD 3'region Proteins 0.000 abstract 1
- 101000948156 Rhodococcus erythropolis Uncharacterized 47.3 kDa protein in thcA 5'region Proteins 0.000 abstract 1
- 101000917565 Rhodococcus fascians Uncharacterized 33.6 kDa protein in fasciation locus Proteins 0.000 abstract 1
- 101000790284 Saimiriine herpesvirus 2 (strain 488) Uncharacterized 9.5 kDa protein in DHFR 3'region Proteins 0.000 abstract 1
- 101000936719 Streptococcus gordonii Accessory Sec system protein Asp3 Proteins 0.000 abstract 1
- 101000936711 Streptococcus gordonii Accessory secretory protein Asp4 Proteins 0.000 abstract 1
- 101000929863 Streptomyces cinnamonensis Monensin polyketide synthase putative ketoacyl reductase Proteins 0.000 abstract 1
- 101000788499 Streptomyces coelicolor Uncharacterized oxidoreductase in mprA 5'region Proteins 0.000 abstract 1
- 101000788468 Streptomyces coelicolor Uncharacterized protein in mprR 3'region Proteins 0.000 abstract 1
- 101001102841 Streptomyces griseus Purine nucleoside phosphorylase ORF3 Proteins 0.000 abstract 1
- 101000708557 Streptomyces lincolnensis Uncharacterized 17.2 kDa protein in melC2-rnhH intergenic region Proteins 0.000 abstract 1
- 101000845085 Streptomyces violaceoruber Granaticin polyketide synthase putative ketoacyl reductase 1 Proteins 0.000 abstract 1
- 101000649826 Thermotoga neapolitana Putative anti-sigma factor antagonist TM1081 homolog Proteins 0.000 abstract 1
- 101000711771 Thiocystis violacea Uncharacterized 76.5 kDa protein in phbC 3'region Proteins 0.000 abstract 1
- 102000006601 Thymidine Kinase Human genes 0.000 abstract 1
- 108020004440 Thymidine kinase Proteins 0.000 abstract 1
- 101710110895 Uncharacterized 7.3 kDa protein in cox-rep intergenic region Proteins 0.000 abstract 1
- 101710095001 Uncharacterized protein in nifU 5'region Proteins 0.000 abstract 1
- 101000711318 Vibrio alginolyticus Uncharacterized 11.6 kDa protein in scrR 3'region Proteins 0.000 abstract 1
- 101000827562 Vibrio alginolyticus Uncharacterized protein in proC 3'region Proteins 0.000 abstract 1
- 101000778915 Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) Uncharacterized membrane protein VP2115 Proteins 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 239000000185 hemagglutinin Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 229940126580 vector vaccine Drugs 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/863—Poxviral vectors, e.g. entomopoxvirus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
- C12N9/1211—Thymidine kinase (2.7.1.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24041—Use of virus, viral particle or viral elements as a vector
- C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Una vacuna del vector poxvirus recombinante de mapache en el que el vector expresa una o más proteínas antigénicas codificadas por multiples cuadros de lectura abiertos, preferiblemente el ORF5, el ORF6 o el ORF3/ORF4/ORF7, de una o más de las cepas del virus del síndrome reproductivo y respiratorio de porcino solo o en combinacion con un cuadro de lectura abierto del circovirus porcino tipo 2 (PCV-2), preferiblemente ORF2, en los sitios de la hemaglutinina (ha) y/o timidina quinasa (tk).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93242107P | 2007-05-30 | 2007-05-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR066812A1 true AR066812A1 (es) | 2009-09-16 |
Family
ID=40088500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080102315A AR066812A1 (es) | 2007-05-30 | 2008-06-02 | Vector poxvirus recombinante de mapache (rrcnv) vacuna recombinante porcina y metodos para inducir un respuesta inmune contra el virus del sindrome reproductivo y respiratorio de porcinos y para prevenir el sindrome reproductivo y respiratorio de porcino y el sindrome de desmedro multisistemico post |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20080299141A1 (es) |
| EP (1) | EP2148928A2 (es) |
| JP (1) | JP2010528604A (es) |
| KR (1) | KR20100025529A (es) |
| CN (1) | CN101730742A (es) |
| AR (1) | AR066812A1 (es) |
| AU (1) | AU2008294036A1 (es) |
| BR (1) | BRPI0812124A2 (es) |
| CA (1) | CA2687026A1 (es) |
| CL (1) | CL2008001557A1 (es) |
| CO (1) | CO6241171A2 (es) |
| MX (1) | MX2009012793A (es) |
| TW (1) | TW200909578A (es) |
| WO (1) | WO2009029130A2 (es) |
| ZA (1) | ZA200908394B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010065140A2 (en) * | 2008-12-05 | 2010-06-10 | Osorio Jorge E | Recombinant raccoon pox virus vaccine against highly pathogenic avian influenza |
| CN103298346A (zh) * | 2010-12-22 | 2013-09-11 | 巴斯夫欧洲公司 | 用于增加植物健康的农用化学品混合物 |
| CA2837375C (en) * | 2011-06-01 | 2019-07-16 | Merial Limited | Needle-free administration of prrsv vaccines |
| CN102488895A (zh) * | 2011-12-30 | 2012-06-13 | 重庆大学 | 一种猪圆环病毒、猪细小病毒、猪繁殖与呼吸综合症病毒三联病毒样颗粒疫苗及其制备方法 |
| CN104211783B (zh) * | 2013-05-22 | 2017-11-07 | 青岛明勤生物科技有限公司 | 一种蓝耳病亚单位疫苗的制备 |
| CN110025781B (zh) * | 2019-04-25 | 2022-09-20 | 杭州牧达智能科技有限公司 | 一种疫苗组合物及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03503482A (ja) * | 1988-02-12 | 1991-08-08 | コモンウェルス・サイエンティフィック・アンド・インダストリアル・リサーチ・オーガナイゼーション | ポックスウイルスベクター |
| US6241989B1 (en) * | 1991-07-09 | 2001-06-05 | Cornell Research Foundation, Inc. | Recombinant multivalent viral vaccine |
| US7087234B1 (en) * | 1991-07-09 | 2006-08-08 | Cornell Research Foundation, Inc. | Recombinant multivalent viral vaccine |
| US5695766A (en) * | 1992-10-30 | 1997-12-09 | Iowa State University Research Foundation | Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome |
| FR2781159B1 (fr) * | 1998-07-06 | 2000-10-06 | Merial Sas | Vaccin circovirus et parvovirus porcin |
| US6391314B1 (en) * | 1997-10-03 | 2002-05-21 | Merial | Porcine circoviruses vaccines diagnostic reagents |
| US6294176B1 (en) * | 1998-07-10 | 2001-09-25 | Schering-Plough Veterinary Corp. | Recombinant raccoonpox virus and uses thereof as a vaccine in mammalian and avian species |
| CA2409874A1 (en) * | 2000-05-24 | 2001-11-29 | Merial | Porcine reproductive and respiratory syndrome virus (prrsv) recombinant avipoxvirus vaccine |
| US7740863B2 (en) * | 2001-04-06 | 2010-06-22 | Merial | Recombinant vaccine against West Nile Virus |
| US7276353B2 (en) * | 2001-12-12 | 2007-10-02 | Virginia Tech Intellectual Properties, Inc. | Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof |
| JP2006503800A (ja) * | 2002-03-13 | 2006-02-02 | メルク エンド カムパニー インコーポレーテッド | Ｈｉｖに対する強化された免疫応答を誘導する方法 |
-
2008
- 2008-05-28 WO PCT/US2008/006735 patent/WO2009029130A2/en active Application Filing
- 2008-05-28 MX MX2009012793A patent/MX2009012793A/es not_active Application Discontinuation
- 2008-05-28 US US12/128,240 patent/US20080299141A1/en not_active Abandoned
- 2008-05-28 CA CA002687026A patent/CA2687026A1/en not_active Abandoned
- 2008-05-28 JP JP2010510317A patent/JP2010528604A/ja not_active Withdrawn
- 2008-05-28 AU AU2008294036A patent/AU2008294036A1/en not_active Abandoned
- 2008-05-28 BR BRPI0812124-9A2A patent/BRPI0812124A2/pt not_active IP Right Cessation
- 2008-05-28 CN CN200880017817A patent/CN101730742A/zh active Pending
- 2008-05-28 KR KR1020097026475A patent/KR20100025529A/ko not_active Application Discontinuation
- 2008-05-28 EP EP08828368A patent/EP2148928A2/en not_active Withdrawn
- 2008-05-29 CL CL200801557A patent/CL2008001557A1/es unknown
- 2008-05-30 TW TW097120321A patent/TW200909578A/zh unknown
- 2008-06-02 AR ARP080102315A patent/AR066812A1/es not_active Application Discontinuation
-
2009
- 2009-11-25 CO CO09134464A patent/CO6241171A2/es not_active Application Discontinuation
- 2009-11-26 ZA ZA200908394A patent/ZA200908394B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101730742A (zh) | 2010-06-09 |
| CO6241171A2 (es) | 2011-01-20 |
| US20080299141A1 (en) | 2008-12-04 |
| EP2148928A2 (en) | 2010-02-03 |
| CA2687026A1 (en) | 2009-03-05 |
| AU2008294036A1 (en) | 2009-03-05 |
| TW200909578A (en) | 2009-03-01 |
| KR20100025529A (ko) | 2010-03-09 |
| BRPI0812124A2 (pt) | 2014-10-14 |
| CL2008001557A1 (es) | 2008-08-22 |
| WO2009029130A2 (en) | 2009-03-05 |
| MX2009012793A (es) | 2010-03-26 |
| WO2009029130A3 (en) | 2009-05-07 |
| ZA200908394B (en) | 2010-08-25 |
| JP2010528604A (ja) | 2010-08-26 |
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| FA | Abandonment or withdrawal |