AR066406A1 - Defensina de planta quimerica - Google Patents

Defensina de planta quimerica

Info

Publication number
AR066406A1
AR066406A1 ARP080101619A ARP080101619A AR066406A1 AR 066406 A1 AR066406 A1 AR 066406A1 AR P080101619 A ARP080101619 A AR P080101619A AR P080101619 A ARP080101619 A AR P080101619A AR 066406 A1 AR066406 A1 AR 066406A1
Authority
AR
Argentina
Prior art keywords
defensin
modified
plant
nucleic acid
transgenic
Prior art date
Application number
ARP080101619A
Other languages
English (en)
Original Assignee
Hexima Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hexima Ltd filed Critical Hexima Ltd
Publication of AR066406A1 publication Critical patent/AR066406A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8282—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for fungal resistance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

Método general para reducir o eliminar un efecto toxico de la expresion de defensina en una planta transgénica hospedante. Además incluye un método para modificar un ácido nucleico que codifica una defensina, un ácido nucleico modificado por la misma y un defensina modificada codificada por la secuencia de ácido nucleico modificada. Incluye una planta transgénica que contiene y que expresa la secuencia de ácidos nucleicos que codifica la defensina modificada, exhibiendo la planta efectos toxicos de defensina reducidos o eliminados, en comparacion con las plantas transgénicas de otro modo comparables que expresan una defensina sin modificar. La defensina modificada se denomina una defensina quimérica que tiene un dominio de defensina maduro de una primera defensina de planta combinada con un dominio de propéptido C-terminal de una segunda defensina de planta o un péptido de translocacion vacuolar.
ARP080101619A 2007-04-20 2008-04-18 Defensina de planta quimerica AR066406A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91298407P 2007-04-20 2007-04-20

Publications (1)

Publication Number Publication Date
AR066406A1 true AR066406A1 (es) 2009-08-19

Family

ID=39874985

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080101619A AR066406A1 (es) 2007-04-20 2008-04-18 Defensina de planta quimerica

Country Status (10)

Country Link
US (1) US20090083880A1 (es)
EP (2) EP2762498A1 (es)
CN (1) CN101848938A (es)
AR (1) AR066406A1 (es)
AU (1) AU2008241364B2 (es)
BR (1) BRPI0810233A2 (es)
CA (1) CA2684575A1 (es)
MX (1) MX2009011287A (es)
WO (1) WO2008128289A1 (es)
ZA (1) ZA200907123B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002063011A1 (en) 2001-02-08 2002-08-15 Hexima Ltd Plant-derived molecules and genetic sequences encoding same and uses therefor
EP2027264B1 (en) * 2006-05-25 2014-10-29 Hexima Limited Multi-gene expression vehicle
AR075257A1 (es) 2008-02-01 2011-03-23 Hexima Ltd Sistema de proteccion de plantas contra la infeccion por agentes patogenos
US9889184B2 (en) 2008-08-05 2018-02-13 Hexima Limited Anti-pathogen systems
CA2733267A1 (en) * 2008-08-05 2010-02-11 Hexima Limited Plant anti-pathogen systems
CN103080127A (zh) * 2010-09-01 2013-05-01 先锋国际良种公司 液泡靶向肽及使用方法
CN103392002B (zh) * 2011-02-07 2017-07-18 赫希玛有限公司 可用作抗病原剂的经修饰植物防卫素
US9943564B2 (en) 2012-11-23 2018-04-17 Hexima Limited Anti-pathogenic methods
CN105358698B (zh) 2013-04-29 2024-02-20 生物催化公司 包含结合至鞘脂的抗体的农用化学组合物
EP3536702A1 (en) * 2013-04-30 2019-09-11 The Donald Danforth Plant Science Center Antifungal plant proteins, peptides, and methods of use
CN106231899A (zh) * 2014-04-23 2016-12-14 赫希玛有限公司 用于处理病原体的试剂和方法
WO2015161348A1 (en) * 2014-04-24 2015-10-29 Hexima Limited Agents and methods of treatment
EP3215624B1 (en) 2014-11-05 2023-11-29 Biotalys NV Transgenic plant comprising a polynucleotide encoding a variable domain of heavy-chain antibody
CN110240638B (zh) * 2019-06-10 2021-11-05 山东农业大学 一种利用生物信息学方法构建的抗菌肽及其应用
CN116410276A (zh) * 2021-12-30 2023-07-11 江苏众红生物工程创药研究院有限公司 重组北艾花粉i型变应原及其制备方法和应用

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5036006A (en) 1984-11-13 1991-07-30 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US4945050A (en) * 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5100792A (en) * 1984-11-13 1992-03-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues
US5004863B2 (en) * 1986-12-03 2000-10-17 Agracetus Genetic engineering of cotton plants and lines
US6268546B1 (en) * 1989-07-19 2001-07-31 Calgene Llc Ovary-tissue transcriptional factors
AU652430B2 (en) * 1991-03-11 1994-08-25 Syngenta Limited Biocidal proteins
US5446127A (en) * 1991-05-24 1995-08-29 Universidad Politecnica De Madrid Antipathogenic peptides and compositions containing the same
US5538525A (en) * 1991-08-29 1996-07-23 Zeneca Limited Biocidal proteins
DE69333782T2 (de) 1992-12-16 2006-01-26 Hexima Ltd., Melbourne Ein proteinase-inhibitor, vorläufer davon und dafür kodierende genetische sequenzen
US6031153A (en) * 1995-01-23 2000-02-29 Novartis Ag Method for protecting plants
GB9525474D0 (en) * 1995-12-13 1996-02-14 Zeneca Ltd Antifungal proteins
JP2000502254A (ja) * 1995-12-13 2000-02-29 ゼネカ・リミテッド 抗真菌タンパク質
US6909032B2 (en) * 1996-01-31 2005-06-21 Commonwealth Scientific And Industrial Research Organisation DNA encoding a macadamia integrifolia anti-microbial protein, constructs comprising the same and plant material comprising the constructs
US5773696A (en) * 1996-03-29 1998-06-30 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
US6121436A (en) * 1996-12-13 2000-09-19 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
AUPO427596A0 (en) * 1996-12-20 1997-01-23 Cooperative Research Centre For Tropical Plant Pathology Anti-microbial protein
GB9818003D0 (en) 1998-08-18 1998-10-14 Zeneca Ltd Polynucleotide sequences
US6855865B2 (en) * 1999-05-07 2005-02-15 E.I. Du Pont De Nemours And Company Nucleic acids encoding plant defensins and methods of use thereof
US6677503B1 (en) * 1999-06-23 2004-01-13 Pioneer Hi-Bred International, Inc. Sunflower anti-pathogene proteins and genes and their uses
US6770750B2 (en) * 1999-11-18 2004-08-03 Korea Kumho Petrochemical Co., Ltd. Small and cysteine rich antifungal defensin and thionin-like protein genes highly expressed in the incompatible interaction
WO2002063011A1 (en) * 2001-02-08 2002-08-15 Hexima Ltd Plant-derived molecules and genetic sequences encoding same and uses therefor
AU2002322388A1 (en) * 2001-06-22 2003-01-08 E.I. Du Pont De Nemours And Company Defensin polynucleotides and methods of use
CN100406190C (zh) * 2001-11-02 2008-07-30 波音公司 形成具有残余压应力分布形式的焊接接头的装置和方法
CA2521940C (en) * 2003-04-23 2010-01-26 Latrobe University Insect chymotrypsin and inhibitors thereof
US20070197474A1 (en) * 2004-03-30 2007-08-23 Clinton William P Methods for controlling plants pathogens using N-phosphonomethylglycine
CA2594053A1 (en) * 2004-12-24 2006-06-29 Anne Rae Vacuole targeting peptide and nucleic acid
EP2027264B1 (en) * 2006-05-25 2014-10-29 Hexima Limited Multi-gene expression vehicle

Also Published As

Publication number Publication date
MX2009011287A (es) 2010-02-18
WO2008128289A1 (en) 2008-10-30
AU2008241364B2 (en) 2013-03-21
ZA200907123B (en) 2010-07-28
AU2008241364A1 (en) 2008-10-30
BRPI0810233A2 (pt) 2014-10-29
EP2762498A1 (en) 2014-08-06
US20090083880A1 (en) 2009-03-26
CA2684575A1 (en) 2008-10-30
EP2148889A4 (en) 2010-06-23
EP2148889A1 (en) 2010-02-03
CN101848938A (zh) 2010-09-29

Similar Documents

Publication Publication Date Title
AR066406A1 (es) Defensina de planta quimerica
MX2010004305A (es) Plantas que tienen rasgos relacionados con el rendimiento aumentado y un metodo para producirlas.
AR069824A1 (es) Plantas con rasgos aumentados relacionados con el rendimiento y un metodo para producirlas
CL2013001124A1 (es) Anticuerpo aislado o una proteína que comprende una porción de enlace de antígeno de un anticuerpo dirigido contra un polipéptido de cd40; composicion farmacéutica que comprende dicho anticuerpo; ácido nucleico que codifica el anticuerpo; vector de clonación; proceso de producción del anticuerpo.
AR067672A1 (es) Plantas que tienen rasgos mejorados relacionados con el rendimiento y un metodo para obtenerlas
AR060273A1 (es) Plantas con caracteristicas relacionadas con el rendimiento aumentado y un metodo para su desarrollo
AR055439A1 (es) Plantas con rendimiento aumentado y metodo para elaborarlas
CL2011001382A1 (es) Anticuerpo o fragmento de union a antigeno especifico para el ligando 1 de muerte programada (pd-li); acido nucleico que lo codifica; vector; celula huesped; proceso de produccion; composicion que lo comprende; y su uso para tratar un trastorno disfuncional de celulas t.
AR111673A1 (es) UNA PLANTA MODIFICADA POR INTRODUCCIÓN DE UNA MOLÉCULA DE ÁCIDO NUCLEICO QUE CODIFICA UNA m⁶ DESMETILASA Y EL MÉTODO PARA SU PRODUCCIÓN
CL2009000210A1 (es) Acidos nucleicos que comprenden una secuencia que codifica un peptido de transito a plastidios de una glaucosafita enlazada a una segunda secuencia que codifica un peptido heterologo; metodo para la expresion estable de un polipeptido heterologo en una planta; polipeptido aislado codificado por el acido nucleico descrito anteriormente.
CL2008003596A1 (es) Fitasa enzimaticamente susceptible, polinucleotido que la codifica, casete de expresion, vector y celula huesped que comprenden dicho acido nucleico; metodo de preparacion de la fitasa, y composiciones que la comprenden.
GB201003701D0 (en) System for the expression of a protein
AR080340A1 (es) Plantas que tienen mejores rasgos relacionados con el rendimiento y un metodo para producirlas mediante la modulacion de la expresion de sgt-1, clcpkg o un polipeptido tipo hd-hidrolasa
AR089830A1 (es) Acido nucleico, vector de expresion, celula bacteriana, celula de planta de citrus y metodo de expresion de un acido nucleico exogeno en la planta de citrus
AR059650A1 (es) Plantas que presentan aumento en el rendimiento y metodo para lograrlo
AR070693A1 (es) Plantas que tienen rasgos aumentados relacionados con el rendimiento y un metodo para obtenerlas a partir de la expresion del polipeptido de nitrato 2 (nrt2)
BR112013001671A8 (pt) feruloil-coa: monolignol transferase.
UY35366A (es) ?genes de toxina y métodos para su uso?.
CL2013000032A1 (es) Metodo para modificar el contenido de glucosinolato (gls) en una planta del orden brassicales que comprende modificar la actividad funcional de al menos una proteina transportadora de glucosinolato (gtr); metodo para reducir la actividad de la gtr en una celula de planta; uso de una secuencia que codifica gtr para obtener planta con contenido modiificado de gsl; gen quimérico; proteina aislada; alelo de gtr mutante.
AR067748A1 (es) Plantas que tienen rasgos mejorados relacionados con el rendimiento y un metodo para obtenerlas
BR112016006383A2 (pt) método de extração de proteína
EA201071408A1 (ru) Способ получения однодольных растений с мужской стерильностью
MX2012005508A (es) Plantas que tienen mejores rasgos relacionados con el rendimiento y un metodo para producirlas.
CL2009001143A1 (es) Metodo para producir polinucleotido promotor quimerico capaz de controlar la transcripcion de un polinucleotido unido operativamente en una celula vegetal o planta; promotor quimerico; construccion genetica que comprende el promotor; celula huesped; metodo para producir expresion modificada de un polinucleotido en una planta.
MX2013013063A (es) Plantas que tienen rasgos mejorados relacionados con el rendimiento y metodo para elaborar las mismas.

Legal Events

Date Code Title Description
FB Suspension of granting procedure