AR064968A1 - Metodo de preparacion de sucralosa por deacilacion de acilato de 6-sucralosa. - Google Patents
Metodo de preparacion de sucralosa por deacilacion de acilato de 6-sucralosa.Info
- Publication number
- AR064968A1 AR064968A1 ARP080100241A ARP080100241A AR064968A1 AR 064968 A1 AR064968 A1 AR 064968A1 AR P080100241 A ARP080100241 A AR P080100241A AR P080100241 A ARP080100241 A AR P080100241A AR 064968 A1 AR064968 A1 AR 064968A1
- Authority
- AR
- Argentina
- Prior art keywords
- sucralose
- acylate
- decilation
- acilate
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Abstract
Un método de preparar sucralosa que incluye mantener una solucion de un acilato de 6-sucralosa en un solvente acuoso a una temperatura en un rango entre -20°C y 20°C y a un pH de al menos 12,2 e inferior a 14,0 durante un periodo de tiempo suficiente para deacilar sustancialmente todo el acilato de 6-sucralosa. El método puede utilizar acilato de 6-sucralosa purificado como material de partida, o el acilato de 6-sucralosa puede estar presente en una mezcla de reaccion enfriada rápidamente resultante de la cloracion de un acilato de 6-sucralosa. La mezcla de reaccion enfriada rápidamente se puede exponer a las condiciones de deacilacion bien antes o después de la retirada de la amida terciaria que puede estar presente en la misma. La sucralosa se recupera subsecuentemente para completar el proceso.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88129207P | 2007-01-19 | 2007-01-19 | |
| US12/004,260 US20080227971A1 (en) | 2007-01-19 | 2007-12-20 | Deacylation of sucralose-6-acylates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR064968A1 true AR064968A1 (es) | 2009-05-06 |
Family
ID=39434019
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080100241A AR064968A1 (es) | 2007-01-19 | 2008-01-18 | Metodo de preparacion de sucralosa por deacilacion de acilato de 6-sucralosa. |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20080227971A1 (es) |
| AR (1) | AR064968A1 (es) |
| TW (1) | TW200840489A (es) |
| WO (1) | WO2008091539A1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR070082A1 (es) * | 2008-01-04 | 2010-03-10 | Tate & Lyle Technology Ltd | Metodo para la produccion de sucralosa |
| CN101977664B (zh) * | 2008-03-20 | 2014-02-26 | 塔特和莱利技术有限公司 | 从叔酰胺溶剂中去除酸 |
| US8436157B2 (en) * | 2008-03-26 | 2013-05-07 | Tate & Lyle Technology Limited | Method for the production of sucralose |
| AR071134A1 (es) * | 2008-04-03 | 2010-05-26 | Tate & Lyle Technology Ltd | Cristalizacion de sucralosa a partir de chorros que contienen sucralosa |
| US8497367B2 (en) * | 2008-04-03 | 2013-07-30 | Tate & Lyle Technology Limited | Sucralose purification process |
| CN101981044B (zh) * | 2008-04-03 | 2014-08-06 | 塔特和莱利技术有限公司 | 碳水化合物浓度对三氯半乳蔗糖萃取效率的影响 |
| US20100022765A1 (en) * | 2008-07-23 | 2010-01-28 | David Losan Ho | Methods for extracting and purifying sucralose intermediate |
| GB2469157B (en) * | 2009-03-30 | 2011-07-06 | John Kerr | Process for removing dimethylamine during sucralose production |
| GB2471348B (en) | 2009-06-22 | 2011-12-14 | Tate & Lyle Technology Ltd | A method for producing sucralose-6-acylate |
| MX2013005560A (es) | 2010-11-23 | 2013-08-26 | Lexington Pharmaceuticals Lab Llc | Cloracion de baja temperatura de carbohidratos. |
| WO2013056128A1 (en) | 2011-10-14 | 2013-04-18 | Lexington Pharmaceuticals Laboratories, Llc | Chlorination of carbohydrates and carbohydrate derivatives |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4950746A (en) * | 1988-07-18 | 1990-08-21 | Noramco, Inc. | Process for synthesizing sucrose derivatives by regioselective reaction |
| US4980463A (en) * | 1989-07-18 | 1990-12-25 | Noramco, Inc. | Sucrose-6-ester chlorination |
| US5089608A (en) * | 1990-03-23 | 1992-02-18 | Mcneil-Ppc, Inc. | Selective 6-acylation of sucrose mediated by cyclic adducts of dialkyltin oxides and diols |
| US5034551A (en) * | 1990-04-23 | 1991-07-23 | Noramco, Inc. | Process for recovery of organotin esters from reaction mixtures containing the same and re-use of the recovered organotin compounds |
| US5023329A (en) * | 1990-04-23 | 1991-06-11 | Noramco, Inc. | Sucrose-6-ester production process |
| US5470969A (en) * | 1990-08-27 | 1995-11-28 | Mcneil-Ppc, Inc. | Catalyzed sucrose-6-ester process |
| US5498709A (en) * | 1994-10-17 | 1996-03-12 | Mcneil-Ppc, Inc. | Production of sucralose without intermediate isolation of crystalline sucralose-6-ester |
| US20060276639A1 (en) * | 2005-06-01 | 2006-12-07 | Healthy Brands, Llc | Conversion of sucralose-6-ester to sucralose |
-
2007
- 2007-12-20 US US12/004,260 patent/US20080227971A1/en not_active Abandoned
-
2008
- 2008-01-17 WO PCT/US2008/000652 patent/WO2008091539A1/en active Application Filing
- 2008-01-18 AR ARP080100241A patent/AR064968A1/es unknown
- 2008-01-18 TW TW097101964A patent/TW200840489A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20080227971A1 (en) | 2008-09-18 |
| TW200840489A (en) | 2008-10-16 |
| WO2008091539A1 (en) | 2008-07-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |