AR064367A1 - Composiciones de diclorohidrato de azimilida - Google Patents
Composiciones de diclorohidrato de azimilidaInfo
- Publication number
- AR064367A1 AR064367A1 ARP070105639A ARP070105639A AR064367A1 AR 064367 A1 AR064367 A1 AR 064367A1 AR P070105639 A ARP070105639 A AR P070105639A AR P070105639 A ARP070105639 A AR P070105639A AR 064367 A1 AR064367 A1 AR 064367A1
- Authority
- AR
- Argentina
- Prior art keywords
- compositions
- dichlorohidrate
- azimilide
- furanyl
- piperazinyl
- Prior art date
Links
- MREBEPTUUMTTIA-PCLIKHOPSA-N Azimilide Chemical compound C1CN(C)CCN1CCCCN1C(=O)N(\N=C\C=2OC(=CC=2)C=2C=CC(Cl)=CC=2)CC1=O MREBEPTUUMTTIA-PCLIKHOPSA-N 0.000 title 1
- 229950001786 azimilide Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- HHPSICLSNHCSNZ-BYEGLACWSA-N 1-[(e)-[5-(4-chlorophenyl)furan-2-yl]methylideneamino]-3-[4-(4-methylpiperazin-1-yl)butyl]imidazolidine-2,4-dione;dihydrochloride Chemical compound Cl.Cl.C1CN(C)CCN1CCCCN1C(=O)N(\N=C\C=2OC(=CC=2)C=2C=CC(Cl)=CC=2)CC1=O HHPSICLSNHCSNZ-BYEGLACWSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Composiciones farmacéuticas de los solvatos y varias formas polimorficas de (E)-1-[[[5-(4-clorofenil)-2-furanilo]metilen]amino]-3-[4-(4-metil-1-piperazinil)butilo]-2,4-imidazolidinadiona diclorhidrato.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87505106P | 2006-12-15 | 2006-12-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR064367A1 true AR064367A1 (es) | 2009-04-01 |
Family
ID=39401118
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP070105639A AR064367A1 (es) | 2006-12-15 | 2007-12-14 | Composiciones de diclorohidrato de azimilida |
Country Status (19)
Country | Link |
---|---|
US (2) | US20080182858A1 (es) |
EP (1) | EP2125791A2 (es) |
JP (1) | JP2010513264A (es) |
KR (1) | KR20090089416A (es) |
CN (1) | CN101558063A (es) |
AR (1) | AR064367A1 (es) |
AU (1) | AU2007331033A1 (es) |
BR (1) | BRPI0720265A2 (es) |
CA (1) | CA2672132A1 (es) |
CL (1) | CL2007003643A1 (es) |
IL (1) | IL198807A0 (es) |
MA (1) | MA30992B1 (es) |
MX (1) | MX2009006475A (es) |
PE (1) | PE20081481A1 (es) |
RU (1) | RU2009117558A (es) |
SM (1) | SMAP200900061A (es) |
TW (1) | TW200840578A (es) |
WO (1) | WO2008072190A2 (es) |
ZA (1) | ZA200903390B (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2016256776B2 (en) * | 2009-03-18 | 2018-04-12 | Incarda Therapeutics, Inc. | Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration |
EP3552603A1 (en) | 2009-03-18 | 2019-10-16 | Incarda Therapeutics, Inc. | Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration |
AU2013248242B2 (en) * | 2009-03-18 | 2016-08-18 | Incarda Therapeutics, Inc | Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration |
CN101735203B (zh) * | 2009-12-17 | 2012-05-23 | 天津药物研究院 | 盐酸阿齐利特的晶型ⅱ及其制备方法和用途 |
US10918798B2 (en) * | 2015-11-27 | 2021-02-16 | Sanofi-Aventis Deutschland Gmbh | Medicament injection device |
EP3411030A4 (en) | 2016-02-01 | 2019-09-04 | InCarda Therapeutics, Inc. | COMBINING ELECTRONIC SURVEILLANCE WITH INHALATION PHARMACOLOGICAL THERAPY FOR MANAGING CARDIAC ARRHYTHMIAS WITH ATRIAL FIBRILLATION |
EP3621616A4 (en) | 2017-05-10 | 2021-01-13 | InCarda Therapeutics, Inc. | UNIT DOSE, AEROSOLS, KITS AND METHODS FOR TREATMENT OF HEART DISEASE BY PULMONAL ADMINISTRATION |
WO2019183470A2 (en) | 2018-03-22 | 2019-09-26 | Incarda Therapeutics, Inc. | A novel method to slow ventricular rate |
US11007185B2 (en) | 2019-08-01 | 2021-05-18 | Incarda Therapeutics, Inc. | Antiarrhythmic formulation |
CN113861164B (zh) * | 2021-10-29 | 2022-09-20 | 迪嘉药业集团有限公司 | 一种烟碱的结晶制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4032645A (en) * | 1975-06-19 | 1977-06-28 | G. D. Searle & Co. | Injectable metronidazole composition |
HU221317B1 (en) * | 1991-08-14 | 2002-09-28 | Procter & Gamble Pharma | 2,4-imidazolidinedione derivatives and antiarrhythmic and antifibrillatory compositions containing them, and process for producing them |
JP4514950B2 (ja) * | 1998-04-29 | 2010-07-28 | ザ プロクター アンド ギャンブル カンパニー | 1,3−二置換−4−オキソ環式尿素の製造方法 |
WO1999055700A1 (en) * | 1998-04-29 | 1999-11-04 | The Procter & Gamble Company | Process for making 1,3-disubstituted-4-oxocyclic ureas |
US7060712B2 (en) * | 2003-05-08 | 2006-06-13 | Theravance, Inc. | Crystalline form of aryl aniline β2 adrenergic receptor agonist |
-
2007
- 2007-12-07 TW TW096146861A patent/TW200840578A/zh unknown
- 2007-12-11 BR BRPI0720265-2A patent/BRPI0720265A2/pt not_active Application Discontinuation
- 2007-12-11 KR KR1020097012327A patent/KR20090089416A/ko not_active Application Discontinuation
- 2007-12-11 CA CA002672132A patent/CA2672132A1/en not_active Abandoned
- 2007-12-11 RU RU2009117558/04A patent/RU2009117558A/ru not_active Application Discontinuation
- 2007-12-11 CN CNA2007800464235A patent/CN101558063A/zh active Pending
- 2007-12-11 EP EP07849435A patent/EP2125791A2/en not_active Withdrawn
- 2007-12-11 WO PCT/IB2007/055037 patent/WO2008072190A2/en active Application Filing
- 2007-12-11 MX MX2009006475A patent/MX2009006475A/es not_active Application Discontinuation
- 2007-12-11 US US12/001,321 patent/US20080182858A1/en not_active Abandoned
- 2007-12-11 AU AU2007331033A patent/AU2007331033A1/en not_active Abandoned
- 2007-12-11 JP JP2009540950A patent/JP2010513264A/ja active Pending
- 2007-12-13 PE PE2007001784A patent/PE20081481A1/es not_active Application Discontinuation
- 2007-12-14 AR ARP070105639A patent/AR064367A1/es not_active Application Discontinuation
- 2007-12-14 CL CL200703643A patent/CL2007003643A1/es unknown
-
2009
- 2009-05-18 ZA ZA200903390A patent/ZA200903390B/xx unknown
- 2009-05-19 IL IL198807A patent/IL198807A0/en unknown
- 2009-06-15 MA MA31991A patent/MA30992B1/fr unknown
- 2009-07-15 SM SM200900061T patent/SMAP200900061A/it unknown
-
2011
- 2011-06-09 US US13/156,810 patent/US20110237603A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2672132A1 (en) | 2008-06-19 |
US20080182858A1 (en) | 2008-07-31 |
JP2010513264A (ja) | 2010-04-30 |
IL198807A0 (en) | 2010-02-17 |
BRPI0720265A2 (pt) | 2014-01-28 |
EP2125791A2 (en) | 2009-12-02 |
WO2008072190A2 (en) | 2008-06-19 |
RU2009117558A (ru) | 2011-01-20 |
WO2008072190A3 (en) | 2008-11-06 |
CN101558063A (zh) | 2009-10-14 |
MA30992B1 (fr) | 2009-12-01 |
AU2007331033A1 (en) | 2008-06-19 |
CL2007003643A1 (es) | 2008-03-24 |
TW200840578A (en) | 2008-10-16 |
SMAP200900061A (it) | 2009-09-07 |
ZA200903390B (en) | 2010-04-28 |
US20110237603A1 (en) | 2011-09-29 |
PE20081481A1 (es) | 2008-11-07 |
KR20090089416A (ko) | 2009-08-21 |
MX2009006475A (es) | 2009-06-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |