AR064232A1 - Uso de complejos metalicos que contienen perfluoroalquilo como medio de contraste para el diagnostico de emfermedad de alzheimer - Google Patents
Uso de complejos metalicos que contienen perfluoroalquilo como medio de contraste para el diagnostico de emfermedad de alzheimerInfo
- Publication number
- AR064232A1 AR064232A1 ARP070102000A ARP070102000A AR064232A1 AR 064232 A1 AR064232 A1 AR 064232A1 AR P070102000 A ARP070102000 A AR P070102000A AR P070102000 A ARP070102000 A AR P070102000A AR 064232 A1 AR064232 A1 AR 064232A1
- Authority
- AR
- Argentina
- Prior art keywords
- complexes containing
- perfluoroalquilo
- alzheimer
- diagnosis
- disease
- Prior art date
Links
- 208000024827 Alzheimer disease Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 208000037259 Amyloid Plaque Diseases 0.000 abstract 1
- 239000002738 chelating agent Substances 0.000 abstract 1
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 229910021645 metal ion Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
Landscapes
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Radiology & Medical Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Uso de complejos metálicos que contienen al menos un radical alquilo perfluorado y al menos un radical agente quelante y al menos un equivalente de ion metálico que los numeros atomicos 21-29, 31-33, 37-39, 42-44, 49 o 47-83, así como sus sales para la produccion de un agente diagnostico para visualizar placas con contenido de amiloides.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102006021495A DE102006021495A1 (de) | 2006-05-09 | 2006-05-09 | Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel zur Diagnose der Alzheimer Krankheit |
Publications (1)
Publication Number | Publication Date |
---|---|
AR064232A1 true AR064232A1 (es) | 2009-03-25 |
Family
ID=38579874
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP070102000A AR064232A1 (es) | 2006-05-09 | 2007-05-09 | Uso de complejos metalicos que contienen perfluoroalquilo como medio de contraste para el diagnostico de emfermedad de alzheimer |
Country Status (8)
Country | Link |
---|---|
US (1) | US20070269384A1 (es) |
AR (1) | AR064232A1 (es) |
DE (1) | DE102006021495A1 (es) |
DO (1) | DOP2007000091A (es) |
PE (1) | PE20081570A1 (es) |
TW (1) | TW200810782A (es) |
UY (1) | UY30332A1 (es) |
WO (1) | WO2007128567A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3101012A1 (en) | 2015-06-04 | 2016-12-07 | Bayer Pharma Aktiengesellschaft | New gadolinium chelate compounds for use in magnetic resonance imaging |
RU2755181C2 (ru) | 2016-11-28 | 2021-09-14 | Байер Фарма Акциенгезельшафт | Новые хелатные соединения гадолиния с высокой релаксивностью для применения в магнитно-резонансной визуализации |
MX2021006024A (es) | 2018-11-23 | 2021-07-06 | Bayer Ag | Formulacion de medios de contraste y proceso para prepararlos. |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19603033A1 (de) * | 1996-01-19 | 1997-07-24 | Schering Ag | Perfluoralkylhaltige Metallkomplexe, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik |
DE19729013A1 (de) * | 1997-07-03 | 1999-02-04 | Schering Ag | Oligomere, perfluoralkylhaltige Verbindungen, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik |
DE19914101C1 (de) * | 1999-03-22 | 2000-10-12 | Schering Ag | Perfluoralkylamide, ihre Herstellung und ihre Verwendung in der Diagnostik |
US6676928B2 (en) * | 2000-08-11 | 2004-01-13 | Schering Aktiengesellschaft | Perfluoroalkyl-containing complexes with polar radicals, process for their production and their use |
US6818203B2 (en) * | 2000-08-11 | 2004-11-16 | Schering Aktiengesellschaft | Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of plaque, tumors and necroses |
DE10066210B4 (de) * | 2000-08-11 | 2008-02-28 | Bayer Schering Pharma Ag | Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Plaques |
DE10231799B4 (de) * | 2002-07-10 | 2006-10-05 | Schering Ag | Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Intravasalen Thromben |
GB0223249D0 (en) * | 2002-10-08 | 2002-11-13 | Amersham Plc | Improved imaging agents |
AU2004206956A1 (en) * | 2003-01-22 | 2004-08-05 | The General Hospital Corporation | Amyloid-binding, metal-chelating agents |
-
2006
- 2006-05-09 DE DE102006021495A patent/DE102006021495A1/de not_active Ceased
-
2007
- 2007-05-07 UY UY30332A patent/UY30332A1/es not_active Application Discontinuation
- 2007-05-08 PE PE2007000556A patent/PE20081570A1/es not_active Application Discontinuation
- 2007-05-08 DO DO2007000091A patent/DOP2007000091A/es unknown
- 2007-05-08 TW TW096116283A patent/TW200810782A/zh unknown
- 2007-05-08 WO PCT/EP2007/004054 patent/WO2007128567A1/de active Application Filing
- 2007-05-08 US US11/797,898 patent/US20070269384A1/en not_active Abandoned
- 2007-05-09 AR ARP070102000A patent/AR064232A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
DE102006021495A1 (de) | 2007-11-15 |
TW200810782A (en) | 2008-03-01 |
US20070269384A1 (en) | 2007-11-22 |
PE20081570A1 (es) | 2009-01-04 |
WO2007128567A1 (de) | 2007-11-15 |
UY30332A1 (es) | 2008-01-02 |
DOP2007000091A (es) | 2008-01-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |