AR063347A1 - Formas cristalinas de docetaxel y proceso para su preparacion - Google Patents

Formas cristalinas de docetaxel y proceso para su preparacion

Info

Publication number
AR063347A1
AR063347A1 ARP070104643A ARP070104643A AR063347A1 AR 063347 A1 AR063347 A1 AR 063347A1 AR P070104643 A ARP070104643 A AR P070104643A AR P070104643 A ARP070104643 A AR P070104643A AR 063347 A1 AR063347 A1 AR 063347A1
Authority
AR
Argentina
Prior art keywords
docetaxel
preparation
crystal forms
desbenzoyl
deacetyltaxol
Prior art date
Application number
ARP070104643A
Other languages
English (en)
Inventor
Chia-Ning Lin
Yuan-Xiu Liao
Tsung-Yu Hsiao
Meng-Fen Ho
Yu-Li Lin
Shu-Ping Chen
Original Assignee
Scinopharm Singapore Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scinopharm Singapore Pte Ltd filed Critical Scinopharm Singapore Pte Ltd
Publication of AR063347A1 publication Critical patent/AR063347A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)

Abstract

Se provee una forma anhidra cristalina de docetaxel y el proceso para preparar docetaxel anhidro y docetaxel trihidrato. Reivindicacion 1: N-Desbenzoil-N-ter-butoxicarboniI-10-desacetiltaxol cristalino anhidro caracterizado por un patron de difraccion por rayos X de polvo con picos en aproximadamente 8,0, 12,4, y 16,8 +- 0,2 grados dos-theta. Reivindicacion 9: N-Desbenzoil-N-ter-butoxicarbonil-10-desacetiltaxol trihidrato cristalino, caracterizado por un patron de difraccion por rayos X de polvo con picos a aproximadamente 8,8, 13,9, 17,7 +- 0,2 grados dos-theta.
ARP070104643A 2006-10-20 2007-10-19 Formas cristalinas de docetaxel y proceso para su preparacion AR063347A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85334106P 2006-10-20 2006-10-20

Publications (1)

Publication Number Publication Date
AR063347A1 true AR063347A1 (es) 2009-01-21

Family

ID=39325127

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP070104643A AR063347A1 (es) 2006-10-20 2007-10-19 Formas cristalinas de docetaxel y proceso para su preparacion

Country Status (10)

Country Link
US (2) US7662980B2 (es)
EP (2) EP2094084A4 (es)
JP (3) JP2010506932A (es)
KR (1) KR101266549B1 (es)
CN (1) CN101534642A (es)
AR (1) AR063347A1 (es)
AU (1) AU2007309534B2 (es)
CA (2) CA2756603C (es)
NZ (1) NZ576355A (es)
WO (1) WO2008051465A2 (es)

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WO2012160568A1 (en) * 2011-05-23 2012-11-29 Shilpa Medicare Limited Process for preparing docetaxel trihydrate polymorph
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
KR101508302B1 (ko) * 2013-06-10 2015-04-06 숭실대학교산학협력단 초음파를 이용한 도세탁셀 수화물 제조방법
EP2865675A1 (en) * 2013-10-23 2015-04-29 INDENA S.p.A. A crystalline anhydrous form of Cabazitaxel, process for the preparation and pharmaceutical compositions thereof
WO2016187147A1 (en) 2015-05-15 2016-11-24 Fl Therapeutics Llc Docetaxel and human serum albumin complexes
CN115487312A (zh) 2016-10-27 2022-12-20 珠海贝海生物技术有限公司 多西他赛和人血清白蛋白的中性pH组合物
CN109836401B (zh) * 2017-11-28 2023-02-14 正大天晴药业集团股份有限公司 一种多西他赛的纯化方法
CN111718316A (zh) * 2020-07-02 2020-09-29 无锡紫杉药业有限公司 一种三水多西他赛生产工艺

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JP2009533330A (ja) * 2006-03-21 2009-09-17 ドクター レディズ ラボラトリーズ リミテッド ドセタキセルの多形体およびプロセス

Also Published As

Publication number Publication date
JP2010506932A (ja) 2010-03-04
CA2667416C (en) 2013-12-17
WO2008051465A3 (en) 2009-04-16
CA2756603A1 (en) 2008-05-02
EP2094084A2 (en) 2009-09-02
EP2330101A1 (en) 2011-06-08
US20080108693A1 (en) 2008-05-08
US7662980B2 (en) 2010-02-16
EP2094084A4 (en) 2010-01-13
KR101266549B1 (ko) 2013-05-24
KR20090080986A (ko) 2009-07-27
US8357811B2 (en) 2013-01-22
AU2007309534A1 (en) 2008-05-02
CN101534642A (zh) 2009-09-16
JP2013155191A (ja) 2013-08-15
WO2008051465A2 (en) 2008-05-02
NZ576355A (en) 2012-04-27
JP2015057423A (ja) 2015-03-26
US20090275762A1 (en) 2009-11-05
CA2756603C (en) 2013-05-28
AU2007309534B2 (en) 2012-08-16
CA2667416A1 (en) 2008-05-02

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