AR061163A1 - Derivados de piridinona n-aril y n-heteroaril sustituidos para usar en enfermedades mediadas por mch-1 - Google Patents
Derivados de piridinona n-aril y n-heteroaril sustituidos para usar en enfermedades mediadas por mch-1Info
- Publication number
- AR061163A1 AR061163A1 ARP070102381A ARP070102381A AR061163A1 AR 061163 A1 AR061163 A1 AR 061163A1 AR P070102381 A ARP070102381 A AR P070102381A AR P070102381 A ARP070102381 A AR P070102381A AR 061163 A1 AR061163 A1 AR 061163A1
- Authority
- AR
- Argentina
- Prior art keywords
- group
- alkyl
- difluorobenzyl
- oxy
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06114917 | 2006-06-02 | ||
| EP06123263 | 2006-10-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR061163A1 true AR061163A1 (es) | 2008-08-06 |
Family
ID=38266244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP070102381A AR061163A1 (es) | 2006-06-02 | 2007-06-01 | Derivados de piridinona n-aril y n-heteroaril sustituidos para usar en enfermedades mediadas por mch-1 |
Country Status (5)
| Country | Link |
|---|---|
| AR (1) | AR061163A1 (fr) |
| PE (1) | PE20080150A1 (fr) |
| TW (1) | TW200811146A (fr) |
| UY (1) | UY30378A1 (fr) |
| WO (1) | WO2007141200A1 (fr) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008041090A1 (fr) * | 2006-10-06 | 2008-04-10 | Pfizer Limited | Pyridinones antagonistes du récepteur 1 de l'hormone de concentration de la mélanine |
| MX2010007430A (es) * | 2008-01-11 | 2010-12-21 | Albany Molecular Res Inc | Piridoindoles (1-azinona)-sustituidos como antagonistas de la hormona de concentracion melanina humana. |
| WO2010104818A1 (fr) * | 2009-03-09 | 2010-09-16 | Bristol-Myers Squibb Company | Analogues d'azapyridone utiles comme antagonistes du récepteur 1 de l'hormone concentrant la mélanine |
| WO2010141545A1 (fr) * | 2009-06-03 | 2010-12-09 | Glaxosmithkline Llc | Bis-pyridylpyridones à usage d'antagonistes de récepteur d'hormone concentrant la mélanine 1 |
| US20120083489A1 (en) * | 2009-06-03 | 2012-04-05 | Christensen Iv Siegfried Benjamin | Bis-pyridylpyridones as melanin-concentrating hormone receptor antagonists |
| WO2011003007A1 (fr) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Antagonistes de mch-1 dazabicycloalcane-indole et dazabicycloalcane-pyrrolo-pyridine, procédés de préparation, et utilisation de ceux-ci |
| US9073925B2 (en) | 2009-07-01 | 2015-07-07 | Albany Molecular Research, Inc. | Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof |
| EP2448585B1 (fr) * | 2009-07-01 | 2014-01-01 | Albany Molecular Research, Inc. | Antagonistes de mch-1 d azépino[b]indole et pyrido-pyrrolo-azépine azinone-substitué, procédés de préparation, et utilisation de ceux-ci |
| WO2011003012A1 (fr) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Antagonistes de mch-1 azapolycycles substitués par azinone, leurs procédés de fabrication et leur utilisation |
| US20120316200A1 (en) * | 2010-04-12 | 2012-12-13 | Merck Sharp & Dohme Corp. | Pyridone derivatives |
| WO2011127643A1 (fr) * | 2010-04-12 | 2011-10-20 | Merck Sharp & Dohme Corp. | Dérivés de pyridone |
| PL2648516T3 (pl) | 2010-12-06 | 2019-04-30 | Aclaris Therapeutics Inc | Podstawione związki pirydynono-pirydynylowe |
| US9359300B2 (en) | 2010-12-06 | 2016-06-07 | Confluence Life Sciences, Inc. | Methyl/difluorophenyl-methoxy substituted pyridinone-pyridinyl compounds, methyl-pyridinyl-methoxy substituted pyridinone-pyridinyl compounds, and methyl-pyrimidinyl-methoxy substituted pyridinone-pyridinyl compounds |
| WO2012088124A2 (fr) | 2010-12-21 | 2012-06-28 | Albany Molecular Research, Inc. | Antagonistes de la mch-1 à base de tétrahydro-azacarboline, leurs procédés de fabrication et leurs utilisations |
| WO2012088038A2 (fr) | 2010-12-21 | 2012-06-28 | Albany Molecular Research, Inc. | Antagonistes de mch-1 consistant en tétrahydro-carbolines substituées par pipérazinone, leurs procédés de fabrication et utilisations |
| WO2013149362A1 (fr) * | 2012-04-06 | 2013-10-10 | Glaxosmithkline Llc | 1-(dihydronaphtalényl)pyridones en tant qu'antagonistes du récepteur 1 de l'hormone de concentration de la mélanine |
| EP2875001B1 (fr) | 2012-07-18 | 2019-01-09 | Sunshine Lake Pharma Co., Ltd. | Dérivés hétérocycliques azotés et leur application dans des médicaments |
| KR102470598B1 (ko) | 2013-06-07 | 2022-11-23 | 어클라리스 쎄라퓨틱스, 인코포레이티드 | 메틸/플루오로-피리디닐-메톡시 치환된 피리디논-피리디닐 화합물 및 플루오로-피리미디닐-메톡시 치환된 피리디논-피리디닐 화합물 |
| AU2014366049B2 (en) | 2013-12-19 | 2018-04-05 | Sunshine Lake Pharma Co., Ltd. | Nitrogenous heterocyclic derivatives and their application in drugs |
| CN116082225A (zh) * | 2016-08-08 | 2023-05-09 | 北京康蒂尼药业股份有限公司 | 一种羟尼酮的制备方法 |
| CN107698498A (zh) * | 2016-08-08 | 2018-02-16 | 罗楹 | 一种羟尼酮的制备方法 |
| EP4076527A4 (fr) * | 2020-01-10 | 2024-05-15 | Consynance Therapeutics, Inc. | Polythérapies de médicaments et leurs méthodes d'utilisation |
| KR20220161390A (ko) | 2020-03-27 | 2022-12-06 | 어클라리스 쎄라퓨틱스, 인코포레이티드 | 면역 병태의 치료를 위한 mk2 경로 억제제의 경구 조성물 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1490064B1 (fr) * | 2002-02-14 | 2009-11-18 | Pharmacia Corporation | Pyridinones substitues comme modulateurs de la p38 map kinase |
| EP1741703A4 (fr) * | 2004-03-05 | 2009-11-25 | Banyu Pharma Co Ltd | Derive pyridone |
| CA2619770A1 (fr) * | 2005-08-24 | 2007-03-01 | Banyu Pharmaceutical Co., Ltd. | Derive phenylpyridone |
-
2007
- 2007-05-31 UY UY30378A patent/UY30378A1/es unknown
- 2007-05-31 PE PE2007000677A patent/PE20080150A1/es not_active Application Discontinuation
- 2007-06-01 AR ARP070102381A patent/AR061163A1/es not_active Application Discontinuation
- 2007-06-01 TW TW096119627A patent/TW200811146A/zh unknown
- 2007-06-01 WO PCT/EP2007/055376 patent/WO2007141200A1/fr active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007141200A8 (fr) | 2008-03-27 |
| TW200811146A (en) | 2008-03-01 |
| PE20080150A1 (es) | 2008-04-11 |
| WO2007141200A1 (fr) | 2007-12-13 |
| UY30378A1 (es) | 2008-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |