AR056729A1 - Compuesto de benzofurano carboxamida, composicion farmaceutica que lo comprende su uso para preparar un medicamento y procesos para su preparcion - Google Patents

Compuesto de benzofurano carboxamida, composicion farmaceutica que lo comprende su uso para preparar un medicamento y procesos para su preparcion

Info

Publication number
AR056729A1
AR056729A1 ARP060104683A ARP060104683A AR056729A1 AR 056729 A1 AR056729 A1 AR 056729A1 AR P060104683 A ARP060104683 A AR P060104683A AR P060104683 A ARP060104683 A AR P060104683A AR 056729 A1 AR056729 A1 AR 056729A1
Authority
AR
Argentina
Prior art keywords
preparation
processes
pharmaceutical composition
benzofuran
prepare
Prior art date
Application number
ARP060104683A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0522071A external-priority patent/GB0522071D0/en
Priority claimed from GB0619950A external-priority patent/GB0619950D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of AR056729A1 publication Critical patent/AR056729A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Un compuesto 4-amino-5-cloro-N-{[1-(tetrahidro-2H-piran-4-ilmetil]metil}-1-benzofuran-7-carboxamida (A), o una de sus sales farmacéuticamente aceptables, por ejemplo hidrocloruro, tosilato como monohidrato o anhidrato. Composicion farmacéutica que lo comprende. Su uso para la preparacion de un medicamento util para el tratamiento de enfermedades tratables mediante agonismo de 5-HT4. Procesos para su preparacion a partir de 4-amino-5-cloro-N-(4-piperidinilmetil)-1-benzofuran-7-carboxamida y tetrahidro-2H-piran-4-carbaldehído o de ácido 4-amino-5-cloro-1-benzofuran-7-carboxílico y {[1-(tetrahídro-2H-piranilmetil)-4-piperidinil]metil}amina.
ARP060104683A 2005-10-28 2006-10-26 Compuesto de benzofurano carboxamida, composicion farmaceutica que lo comprende su uso para preparar un medicamento y procesos para su preparcion AR056729A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0522071A GB0522071D0 (en) 2005-10-28 2005-10-28 Novel compound
GB0619950A GB0619950D0 (en) 2006-10-09 2006-10-09 Novel compounds

Publications (1)

Publication Number Publication Date
AR056729A1 true AR056729A1 (es) 2007-10-17

Family

ID=37591731

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060104683A AR056729A1 (es) 2005-10-28 2006-10-26 Compuesto de benzofurano carboxamida, composicion farmaceutica que lo comprende su uso para preparar un medicamento y procesos para su preparcion

Country Status (4)

Country Link
AR (1) AR056729A1 (es)
PE (1) PE20070713A1 (es)
TW (1) TW200732327A (es)
WO (1) WO2007048643A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013518085A (ja) 2010-02-01 2013-05-20 ノバルティス アーゲー CRF−1受容体アンタゴニストとしてのピラゾロ[5,1b]オキサゾール誘導体
AR080056A1 (es) 2010-02-01 2012-03-07 Novartis Ag Derivados de ciclohexil-amida como antagonistas de los receptores de crf
JP5748777B2 (ja) 2010-02-02 2015-07-15 ノバルティス アーゲー Crf受容体アンタゴニストとしてのシクロヘキシルアミド誘導体
MA41633B1 (fr) * 2015-02-13 2019-07-31 Suven Life Sciences Ltd Composés amide en tant qu'agonistes du récepteur 5-ht4

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0820586A (ja) * 1994-07-05 1996-01-23 Sanwa Kagaku Kenkyusho Co Ltd 1−アザビシクロ[3.3.0]オクタン誘導体、その塩及び製法並びに用途
WO2005092882A1 (en) * 2004-03-01 2005-10-06 Pfizer Japan, Inc. 4-amino-5-halogeno-benzamide derivatives as 5-ht4 receptor agonists for the treatment of gastrointestinal, cns, neurological and cardiovascular disorders

Also Published As

Publication number Publication date
TW200732327A (en) 2007-09-01
WO2007048643A1 (en) 2007-05-03
PE20070713A1 (es) 2007-09-27

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