UA107702C2 - Novel benzamide derivatives - Google Patents

Novel benzamide derivatives

Info

Publication number
UA107702C2
UA107702C2 UAA201213255A UAA201213255A UA107702C2 UA 107702 C2 UA107702 C2 UA 107702C2 UA A201213255 A UAA201213255 A UA A201213255A UA A201213255 A UAA201213255 A UA A201213255A UA 107702 C2 UA107702 C2 UA 107702C2
Authority
UA
Ukraine
Prior art keywords
benzamide derivatives
novel benzamide
derivative
novel
benzamide
Prior art date
Application number
UAA201213255A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Soon-Hoe Kim
Weon-Bin Im
Sung-Hak Choi
Sun-Ho Choi
Ju-Hee Sohn
Hyun-Jung Sung
Mi-Yeon Kim
Kang-Hun Cho
Tae-Kyoung Sohn
Original Assignee
Dong A Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong A Pharm Co Ltd filed Critical Dong A Pharm Co Ltd
Publication of UA107702C2 publication Critical patent/UA107702C2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms

Abstract

Даний винахід стосується нової похідної бензаміду або її фармацевтично прийнятної солі, способу її отримання і агоніста рецептора 5-НТ, що містить цю похідну як активний інгредієнт.Похідні бензаміду даного винаходу мають чудову афінність до рецепторів 5-НТ, можливість скоротити час спорожнення шлунка і низьку токсичність і, отже, є терапевтично ефективними для лікування різних захворювань, пов'язаних з рецепторами 5-НТ.The present invention relates to a new derivative of benzamide or its pharmaceutically acceptable salt, method of production thereof and a 5-HT receptor agonist containing this derivative as the active ingredient. toxicity and, therefore, are therapeutically effective for the treatment of various diseases associated with 5-HT receptors.

UAA201213255A 2010-04-23 2011-04-18 Novel benzamide derivatives UA107702C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020100038039A KR101180174B1 (en) 2010-04-23 2010-04-23 Novel benzamide derivatives
PCT/KR2011/002759 WO2011132901A2 (en) 2010-04-23 2011-04-18 Novel benzamide derivatives

Publications (1)

Publication Number Publication Date
UA107702C2 true UA107702C2 (en) 2015-02-10

Family

ID=44834616

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201213255A UA107702C2 (en) 2010-04-23 2011-04-18 Novel benzamide derivatives

Country Status (19)

Country Link
US (1) US9221790B2 (en)
EP (1) EP2560955B1 (en)
JP (1) JP5564147B2 (en)
KR (1) KR101180174B1 (en)
CN (1) CN102844301B (en)
AU (1) AU2011243393B2 (en)
BR (1) BR112012026509B1 (en)
CA (1) CA2794176C (en)
ES (1) ES2594708T3 (en)
HK (1) HK1176061A1 (en)
IL (1) IL222491A (en)
MX (1) MX2012011721A (en)
MY (1) MY162554A (en)
NZ (1) NZ602612A (en)
RU (1) RU2536688C2 (en)
SG (1) SG184350A1 (en)
UA (1) UA107702C2 (en)
WO (1) WO2011132901A2 (en)
ZA (1) ZA201207903B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101341692B1 (en) 2011-03-16 2013-12-20 동아에스티 주식회사 Composition comprising the extract of herbal combination for preventing or treating diabetic peripheral neuropathy
KR101341693B1 (en) 2011-03-16 2013-12-16 동아에스티 주식회사 Composition comprising the extract of herbs for preventing or treating neurodegenerative disorders
KR101457789B1 (en) 2013-02-13 2014-11-03 동아제약 주식회사 Film-forming pharmaceutical compositions for wound treatment and the production method thereof
US9771348B2 (en) 2013-07-25 2017-09-26 Dong-A St Co., Ltd Method for preparing benzamide derivative, novel intermediate used in preparation of benzamide, and method for preparing novel intermediate
CN104230889A (en) * 2014-08-29 2014-12-24 南京大学 Ciprofloxacin derivatives and preparation method and use of ciprofloxacin derivatives
KR102394635B1 (en) * 2015-03-31 2022-05-09 (주)아모레퍼시픽 Composition for anti-oxidation or anti-aging containing 5-Adamantan-1-yl-N-(2,4-dihydroxy-benzyl)-2,4-dimethoxy-benzamide

Family Cites Families (20)

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GB1507462A (en) 1974-03-21 1978-04-12 Gallardo Antonio Sa N-heterocyclic substituted benzamides methods for their preparation and compositions containing them
US5057525A (en) 1981-10-01 1991-10-15 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl) benzamide derivatives
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EP1131290B1 (en) * 1998-11-20 2008-02-20 F. Hoffmann-La Roche Ag Piperidine ccr-3 receptor antagonists
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FR2861073B1 (en) * 2003-10-17 2006-01-06 Sanofi Synthelabo N- [HETEROARYL (PIPERIDIN-2-YL) METHYL] BENZAMIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF
KR100854211B1 (en) 2003-12-18 2008-08-26 동아제약주식회사 Novel oxazolidinone derivatives, a process for the preparation thereof and pharmaceutical composition comprising the same for antibiotics
KR100976063B1 (en) 2007-03-16 2010-08-17 동아제약주식회사 Novel benzamide derivatives and process for the preparation thereof
JP5148686B2 (en) 2007-04-19 2013-02-20 ドン・ア・ファーム・カンパニー・リミテッド DPP-IV inhibitor containing β-amino group, method for producing the same, and pharmaceutical composition for preventing and treating diabetes or obesity containing the same as an active ingredient
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WO2010062959A1 (en) 2008-11-26 2010-06-03 Aryx Therapeutics, Inc. 5-ht4 receptor agonists for treating irritable bowel syndrome and colonic hypersensitivity
WO2011118976A2 (en) 2010-03-24 2011-09-29 Dong-A Pharm. Co., Ltd. Pharmaceutical composition for the prevention or the treatment of non-alcoholic fatty liver disease and the method for prevention or treatment of non-alcoholic fatty liver disease using the same
SG190415A1 (en) 2010-11-24 2013-06-28 Dong A St Co Ltd Quinoline derivative compound, method for preparing same, and pharmaceutical composition containing same
US20140155609A9 (en) 2010-11-24 2014-06-05 Dong-A St Co., Ltd. Quinoline derivative compound, method for preparing same, and pharmaceutical composition containing same
KR101341693B1 (en) 2011-03-16 2013-12-16 동아에스티 주식회사 Composition comprising the extract of herbs for preventing or treating neurodegenerative disorders
KR101341692B1 (en) 2011-03-16 2013-12-20 동아에스티 주식회사 Composition comprising the extract of herbal combination for preventing or treating diabetic peripheral neuropathy

Also Published As

Publication number Publication date
JP2013525344A (en) 2013-06-20
CN102844301A (en) 2012-12-26
JP5564147B2 (en) 2014-07-30
BR112012026509A2 (en) 2017-10-31
CA2794176A1 (en) 2011-10-27
IL222491A (en) 2016-07-31
HK1176061A1 (en) 2013-07-19
IL222491A0 (en) 2012-12-31
MY162554A (en) 2017-06-15
BR112012026509B1 (en) 2021-01-19
CA2794176C (en) 2015-12-15
AU2011243393B2 (en) 2014-07-17
MX2012011721A (en) 2012-12-17
EP2560955B1 (en) 2016-06-29
EP2560955A4 (en) 2013-09-11
WO2011132901A2 (en) 2011-10-27
US9221790B2 (en) 2015-12-29
ES2594708T3 (en) 2016-12-22
KR20110118446A (en) 2011-10-31
EP2560955A2 (en) 2013-02-27
ZA201207903B (en) 2013-06-26
WO2011132901A3 (en) 2012-01-26
CN102844301B (en) 2015-04-22
AU2011243393A1 (en) 2012-10-18
US20130085160A1 (en) 2013-04-04
SG184350A1 (en) 2012-11-29
RU2536688C2 (en) 2014-12-27
NZ602612A (en) 2014-11-28
RU2012150037A (en) 2014-05-27
KR101180174B1 (en) 2012-09-05

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