AR055838A1 - Formulaciones para microproyecciones recubiertas que tienen solubilidad controlada - Google Patents

Formulaciones para microproyecciones recubiertas que tienen solubilidad controlada

Info

Publication number
AR055838A1
AR055838A1 ARP060100115A ARP060100115A AR055838A1 AR 055838 A1 AR055838 A1 AR 055838A1 AR P060100115 A ARP060100115 A AR P060100115A AR P060100115 A ARP060100115 A AR P060100115A AR 055838 A1 AR055838 A1 AR 055838A1
Authority
AR
Argentina
Prior art keywords
microprojections
formulations
covered
solubility
controlled solubility
Prior art date
Application number
ARP060100115A
Other languages
English (en)
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of AR055838A1 publication Critical patent/AR055838A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles

Abstract

La invencion proporciona una formulacion para recubrir una o más microproyecciones usando un contra-ion no volátil para mejorar la solubilidad de un agente biologicamente activo. La invencion también incluye formulaciones que tiene un contra-ion volátil para reducir la solubilidad de una pare del agente biologicamente activo.
ARP060100115A 2005-01-12 2006-01-11 Formulaciones para microproyecciones recubiertas que tienen solubilidad controlada AR055838A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/034,891 US20050123507A1 (en) 2003-06-30 2005-01-12 Formulations for coated microprojections having controlled solubility

Publications (1)

Publication Number Publication Date
AR055838A1 true AR055838A1 (es) 2007-09-12

Family

ID=36177752

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060100115A AR055838A1 (es) 2005-01-12 2006-01-11 Formulaciones para microproyecciones recubiertas que tienen solubilidad controlada

Country Status (8)

Country Link
US (1) US20050123507A1 (es)
EP (1) EP1835857A1 (es)
CN (1) CN101137333A (es)
AR (1) AR055838A1 (es)
AU (1) AU2006204977A1 (es)
CA (1) CA2593111A1 (es)
TW (1) TW200635620A (es)
WO (1) WO2006076403A1 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69719761T2 (de) * 1996-06-18 2003-12-18 Alza Corp Vorrichtung zur verbesserung der transdermalen verabreichung von medikamenten oder der abnahme von körperflüssigkeiten
EP1341453B1 (en) * 2000-10-13 2009-04-15 Alza Corporation Apparatus and method for piercing skin with microprotrusions
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
IL155583A0 (en) * 2000-10-26 2003-11-23 Alza Corp Transdermal drug delivery devices having coated microprotrusions
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
MXPA06000281A (es) * 2003-06-30 2006-07-03 Johnson & Johnson Formulaciones para microproyecciones revestidas que contienen contraiones no volatiles.
ATE539687T1 (de) 2003-10-31 2012-01-15 Alza Corp Selbstbetätigter applikator für eine mikroprojektionsanordnung
EP1682012A4 (en) * 2003-11-13 2008-09-24 Alza Corp COMPOSITION AND APPARATUS FOR TRANSDERMAL DELIVERY
KR20070011481A (ko) * 2004-04-13 2007-01-24 알자 코포레이션 다중 백신의 경피 전달용 기구 및 방법
AU2005244734A1 (en) 2004-05-13 2005-12-01 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
AU2005282401A1 (en) * 2004-09-08 2006-03-16 Alza Corporation Microprojection array with improved skin adhesion and compliance
JP2009507576A (ja) * 2005-09-12 2009-02-26 アルザ コーポレイション 被膜可能な経皮送達微小突起アセンブリ
CA2635251A1 (en) * 2005-12-28 2007-07-26 Alza Corporation Stable therapeutic formulations
CN101466393A (zh) * 2006-03-15 2009-06-24 阿尔扎公司 用于经皮递送甲状旁腺激素药剂以治疗骨质减少的方法
WO2007127815A2 (en) * 2006-04-25 2007-11-08 Alza Corporation Microprojection array application with multilayered microprojection member for high drug loading
US20070293816A1 (en) * 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
US7771542B1 (en) 2006-05-30 2010-08-10 Stone Chemical Company Compositions and methods for removing lead from metal surfaces
US8377863B2 (en) * 2007-05-29 2013-02-19 Unigene Laboratories Inc. Peptide pharmaceutical for oral delivery
KR101430627B1 (ko) 2008-05-13 2014-08-14 유니버시티 오브 캔사스 금속 추출 펩타이드(ｍａｐ) 태그 및 관련된 방법
US9187735B2 (en) 2012-06-01 2015-11-17 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
CN107106658B (zh) * 2014-10-27 2021-07-09 久光制药株式会社 含有基因重组型卵泡刺激激素的微针装置
CA2973099C (en) 2015-01-12 2021-09-14 Enteris Biopharma, Inc. Solid oral dosage forms
CN112719289B (zh) * 2020-12-09 2022-09-09 暨南大学 一种微喷射三维智能打印复杂结构超高温Nb-Si基合金的方法

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3136314A (en) * 1960-08-01 1964-06-09 Kravitz Harvey Vaccinating devices
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) * 1972-02-14 1973-08-13 Ici Ltd Pansements
OA05448A (fr) * 1975-10-16 1981-03-31 Manufrance Manufacture Francai Dispositif vaccinateur multipénétrant.
FR2474856A1 (fr) * 1980-01-31 1981-08-07 Merieux Inst Dispositif scarificateur
DE3722775A1 (de) * 1987-07-09 1989-01-19 Lohmann Therapie Syst Lts Transdermales therapeutisches system
EP0429842B1 (en) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5279544A (en) * 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
DE4341444C2 (de) * 1993-12-04 1996-03-14 Lohmann Therapie Syst Lts Wirkstoffhaltiges Pflaster und Verfahren zu seiner Herstellung
US5487726A (en) * 1994-06-16 1996-01-30 Ryder International Corporation Vaccine applicator system
US6290991B1 (en) * 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US5866536A (en) * 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
AU5740496A (en) * 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
AU5869796A (en) * 1995-05-22 1996-12-11 Ned A. Godshall Micromechanical patch for enhancing the delivery of compound s through the skin
DE69719761T2 (de) * 1996-06-18 2003-12-18 Alza Corp Vorrichtung zur verbesserung der transdermalen verabreichung von medikamenten oder der abnahme von körperflüssigkeiten
US5741554A (en) * 1996-07-26 1998-04-21 Bio Dot, Inc. Method of dispensing a liquid reagent
US5916524A (en) * 1997-07-23 1999-06-29 Bio-Dot, Inc. Dispensing apparatus having improved dynamic range
US5738728A (en) * 1996-07-26 1998-04-14 Bio Dot, Inc. Precision metered aerosol dispensing apparatus
US5743960A (en) * 1996-07-26 1998-04-28 Bio-Dot, Inc. Precision metered solenoid valve dispenser
WO1998011937A1 (en) * 1996-09-17 1998-03-26 Deka Products Limited Partnership System for delivery of drugs by transport
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
CN1206004C (zh) * 1997-12-11 2005-06-15 阿尔扎有限公司 增强透皮物剂流量的装置
ATE221400T1 (de) * 1997-12-11 2002-08-15 Alza Corp Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
PT1037686E (pt) * 1997-12-11 2005-10-31 Alza Corp Aparelho para potenciar o fluxo de agente transdermico
US6091975A (en) * 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
US6884427B1 (en) * 1999-02-08 2005-04-26 Aderans Research Institute, Inc. Filamentary means for introducing agents into tissue of a living host
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6379324B1 (en) * 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6623457B1 (en) * 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US6835184B1 (en) * 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
US20020095134A1 (en) * 1999-10-14 2002-07-18 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
US6565532B1 (en) * 2000-07-12 2003-05-20 The Procter & Gamble Company Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup
US6537242B1 (en) * 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US20050008683A1 (en) * 2000-06-29 2005-01-13 Becton Dickinson And Company Method for delivering interferons to the intradermal compartment
US6589202B1 (en) * 2000-06-29 2003-07-08 Becton Dickinson And Company Method and apparatus for transdermally sampling or administering a substance to a patient
US6440096B1 (en) * 2000-07-14 2002-08-27 Becton, Dickinson And Co. Microdevice and method of manufacturing a microdevice
CA2425537C (en) * 2000-10-13 2009-09-08 Alza Corporation Microblade array impact applicator
EP1341453B1 (en) * 2000-10-13 2009-04-15 Alza Corporation Apparatus and method for piercing skin with microprotrusions
NZ525295A (en) * 2000-10-13 2005-05-27 Alza Corp Microprotrusion member retainer for impact applicator
IL155583A0 (en) * 2000-10-26 2003-11-23 Alza Corp Transdermal drug delivery devices having coated microprotrusions
US9302903B2 (en) * 2000-12-14 2016-04-05 Georgia Tech Research Corporation Microneedle devices and production thereof
WO2002074173A1 (en) * 2001-03-16 2002-09-26 Alza Corporation Method and apparatus for coating skin piercing microprojections
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
WO2002085447A2 (en) * 2001-04-20 2002-10-31 Alza Corporation Microprojection array having a beneficial agent containing coating
US6881203B2 (en) * 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
CA2500453A1 (en) * 2001-09-28 2003-04-03 Biovalve Technologies, Inc. Microneedle with membrane
US6689100B2 (en) * 2001-10-05 2004-02-10 Becton, Dickinson And Company Microdevice and method of delivering or withdrawing a substance through the skin of an animal
EP1485317A2 (en) * 2001-11-30 2004-12-15 Alza Corporation Methods and apparatuses for forming microprojection arrays
EP1465535B1 (en) * 2001-12-20 2007-11-28 ALZA Corporation Skin-piercing microprojections having piercing depth control
CA2490545A1 (en) * 2002-06-28 2004-01-08 Alza Corporation Transdermal drug delivery devices having coated microprotrusions
AR042815A1 (es) * 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
MXPA06000281A (es) * 2003-06-30 2006-07-03 Johnson & Johnson Formulaciones para microproyecciones revestidas que contienen contraiones no volatiles.
ATE539687T1 (de) * 2003-10-31 2012-01-15 Alza Corp Selbstbetätigter applikator für eine mikroprojektionsanordnung
EP1682012A4 (en) * 2003-11-13 2008-09-24 Alza Corp COMPOSITION AND APPARATUS FOR TRANSDERMAL DELIVERY
WO2006079019A2 (en) * 2005-01-21 2006-07-27 Alza Corporation Therapeutic peptide formulations for coating microneedles with improved stabitity containing at least one counterion

Also Published As

Publication number Publication date
EP1835857A1 (en) 2007-09-26
WO2006076403A1 (en) 2006-07-20
AU2006204977A1 (en) 2006-07-20
CN101137333A (zh) 2008-03-05
TW200635620A (en) 2006-10-16
CA2593111A1 (en) 2006-07-20
US20050123507A1 (en) 2005-06-09

Similar Documents

Publication Publication Date Title
AR055838A1 (es) Formulaciones para microproyecciones recubiertas que tienen solubilidad controlada
AR054227A1 (es) Composicion de principios activos
CR10975A (es) Formulaciones para el tratamiento del cancer
CR20110110A (es) Composicion farmaceutica
BR112015023391A2 (pt) formulações compreendendo conjugado droga-anticorpo anti-egfr
PE20160527A1 (es) Formulaciones de adenovirus mejoradas
ECSP109852A (es) Uso de homo y copolímeros para la estabilización de formulaciones de principios activos
BR112012022797A2 (pt) composição farmacêutica resistente a álcool, e, método para tratar uma doença com uma formulação de agente ativo resistente a álcool
CL2010001260A1 (es) Composicion farmaceutica que comprende una sal de estroncio y vitamina d y una ciclodextrina, donde la relacion masica entre la cantidad de vitamina d y la cantidad de ciclodextrina esta comprendida entre 1/40 y 1/800, util para tratar o prevenir osteoporosis.
AR053026A1 (es) Composiciones de anticuerpos anti factor de estimulacion de colonias de macrofagos (anti-m csf)
CR11137A (es) Valvulas prosteticas de corazon
PE20142362A1 (es) Agentes de iarn, composiciones y metodos de uso de los mismos para tratar enfermedades asociadas con transtiretina (ttr)
SV2008003071A (es) Composiciones farmaceuticas de antagonistas del anticuerpo anti-cd40
AR067309A1 (es) Formulaciones farmaceuticas que contienen derivados de acido lipoico
CL2015003072A1 (es) Formulaciones de liberación prolongada de colchicina y métodos de uso de las mismas.
PA8660701A1 (es) Agonistas de pyy y sus usos
UY36542A (es) Formulaciones farmacéuticas para anticuerpos anti-tnf-alfa
BRPI0806531A2 (pt) Composto, composição farmacêutica, agente terapêutico, e, uso do composto.
BRPI0815577A2 (pt) Peptídeo foxm1 e agente medicinal compreendendo o mesmo.
CL2008000442A1 (es) Composicion farmaceutica que comprende a un quitosano, un ingrediente activo cosmetico o farmaceutico, y un solvente volatil; y su uso para tratar psoriasis, micosis entre otras enfermedades.
CO6300964A2 (es) Una composicion farmaceutica que comprende una combinacion de un agente quimioterapeutico y un anticuerpo 3 antiglipicano
CL2013001202A1 (es) Metodo para prevenir enfermedades de plantas que comprende aplicar un agente para el tratamiento del suelo, donde el agente comprende compuestos derivados de quinolina o sus sales como ingrediente activo.
NI201100025A (es) Métodos de administración de las formulaciones tópicas antimicóticas para el tratamiento de las infecciones por hongos.
PA8720801A1 (es) Nuevas combinaciones terapeuticas para el tratamiento de la depresion
CL2007003356A1 (es) Compuestos derivados de benzopirazoles; proceso para la preparacion de dichos compuestos; composicion farmaceutica que comprende a dichos compuestos y otro agente activo; y su uso para el tratamiento del asma, inflamacion, entre otras enfermedades.

Legal Events

Date Code Title Description
FA Abandonment or withdrawal