AR055562A1 - Derivados 1,3 oxazina y composiciones farmaceuticas que los comprenden. - Google Patents
Derivados 1,3 oxazina y composiciones farmaceuticas que los comprenden.Info
- Publication number
- AR055562A1 AR055562A1 ARP060100674A ARP060100674A AR055562A1 AR 055562 A1 AR055562 A1 AR 055562A1 AR P060100674 A ARP060100674 A AR P060100674A AR P060100674 A ARP060100674 A AR P060100674A AR 055562 A1 AR055562 A1 AR 055562A1
- Authority
- AR
- Argentina
- Prior art keywords
- pharmaceutical compositions
- diseases
- understand
- different genesis
- halogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Compuestos de formula (1) y composiciones farmacéuticas que los comprenden. Reivindicacion 1. Empleo de compuestos de la formula general (1) en la cual representan R1 y R2 iguales o idénticos, H, halogeno, alquilo C1-4- o en forma conjunta alquileno C1-6- y R3 H, halogeno, OH, alquilo C1-4- o alquilo C1-4-O-; para la preparacion de un medicamento para el tratamiento de enfermedades de las vías respiratorias, que se seleccionan del grupo que consiste en enfermedades pulmonares obstructivas de diferentes génesis, enfisemas pulmonares de diferentes génesis, enfermedades pulmonares restrictivas, enfermedades pulmonares intersticiales, fibrosis císticas, bronquitis de diferente génesis, bronquiectasias, ARDS (adult respiratory distress syndrom, síntoma de dificultad respiratoria adulta) y todas las formas del edema pulmonar.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005008921A DE102005008921A1 (de) | 2005-02-24 | 2005-02-24 | Neue Arzneimittel zur Behandlung von Atemwegserkrankungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR055562A1 true AR055562A1 (es) | 2007-08-22 |
Family
ID=36179764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060100674A AR055562A1 (es) | 2005-02-24 | 2006-02-24 | Derivados 1,3 oxazina y composiciones farmaceuticas que los comprenden. |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US20060189605A1 (es) |
| EP (1) | EP1856070B1 (es) |
| JP (1) | JP4950075B2 (es) |
| KR (1) | KR20070110386A (es) |
| CN (1) | CN101128444A (es) |
| AR (1) | AR055562A1 (es) |
| AT (1) | ATE517877T1 (es) |
| AU (1) | AU2006218010B2 (es) |
| BR (1) | BRPI0607258A2 (es) |
| CA (1) | CA2598914A1 (es) |
| DE (1) | DE102005008921A1 (es) |
| DK (1) | DK1856070T3 (es) |
| EA (1) | EA012439B1 (es) |
| ES (1) | ES2370653T3 (es) |
| IL (1) | IL185444A0 (es) |
| MX (1) | MX2007010363A (es) |
| MY (1) | MY146802A (es) |
| NO (1) | NO20073176L (es) |
| NZ (1) | NZ561743A (es) |
| PE (1) | PE20061097A1 (es) |
| PL (1) | PL1856070T3 (es) |
| TW (1) | TWI369988B (es) |
| UA (1) | UA90504C2 (es) |
| UY (1) | UY29394A1 (es) |
| WO (1) | WO2006089859A1 (es) |
| ZA (1) | ZA200704727B (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005008921A1 (de) * | 2005-02-24 | 2006-08-31 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittel zur Behandlung von Atemwegserkrankungen |
| US7423146B2 (en) | 2005-11-09 | 2008-09-09 | Boehringer Ingelheim International Gmbh | Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones |
| WO2008023001A1 (en) * | 2006-08-22 | 2008-02-28 | Boehringer Ingelheim International Gmbh | Powder formulations for inhalation containing enantiomerically pure beta-agonists |
| UY30550A1 (es) * | 2006-08-22 | 2008-03-31 | Boehringer Ingelheim Int | Nuevos beta-agonistas enantioméricamente puros, procedimientos para su preparacion y su uso como medicamentos |
| PE20080425A1 (es) * | 2006-08-22 | 2008-06-16 | Boehringer Ingelheim Int | Formulacion aerosol para la inhalacion de beta-agonistas |
| UY30552A1 (es) * | 2006-08-22 | 2008-03-31 | Boehringer Ingelheim Int | Combinaciones farmacologiicas en base a derivados sustituidos de la n-(5-{2-[1,1-dimetil-propilamino]-1-hidroxi-metil}-2-hidroxi-fenil)-metansulfonamida y aplicaciones |
| EP2093219A1 (de) | 2008-02-22 | 2009-08-26 | Boehringer Ingelheim International Gmbh | Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel |
| GB201217330D0 (en) * | 2012-09-28 | 2012-11-14 | Univ Cardiff | Therapeutic for treating inflammatory lung disorders |
| AU2015370463B2 (en) * | 2014-12-24 | 2020-12-24 | Kither Biotech S.R.L. | Novel PI3K gamma inhibitor peptide for treatment of respiratory system diseases |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3026534A1 (de) * | 1980-07-12 | 1982-03-18 | C.H. Boehringer Sohn, 6507 Ingelheim | 3,1-benzoxazin-2-one, ihre herstellung und verwendung |
| US4460581A (en) * | 1982-10-12 | 1984-07-17 | Boehringer Ingelheim Kg | (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones |
| US4570630A (en) * | 1983-08-03 | 1986-02-18 | Miles Laboratories, Inc. | Medicament inhalation device |
| DE3609152A1 (de) * | 1986-03-19 | 1987-09-24 | Bayer Ag | Verfahren zur herstellung des (-)-antipoden des (e)-1-cyclohexyl-4,4-dimethyl- 3-hydroxy-2-(1,2,4-triazol-1-yl)-pent-1-ens |
| JP4516064B2 (ja) * | 2003-04-04 | 2010-08-04 | ノバルティス アーゲー | 気道疾患の処置のためのキノリン−２−オン誘導体 |
| DE102004003428A1 (de) * | 2004-01-23 | 2005-08-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue langwirksame Beta-2-Agonisten, und deren Verwendung als Arzneimittel |
| US7220742B2 (en) * | 2004-05-14 | 2007-05-22 | Boehringer Ingelheim International Gmbh | Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments |
| DE102005008921A1 (de) * | 2005-02-24 | 2006-08-31 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittel zur Behandlung von Atemwegserkrankungen |
| US7423146B2 (en) * | 2005-11-09 | 2008-09-09 | Boehringer Ingelheim International Gmbh | Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones |
| PE20080425A1 (es) * | 2006-08-22 | 2008-06-16 | Boehringer Ingelheim Int | Formulacion aerosol para la inhalacion de beta-agonistas |
| UY30552A1 (es) * | 2006-08-22 | 2008-03-31 | Boehringer Ingelheim Int | Combinaciones farmacologiicas en base a derivados sustituidos de la n-(5-{2-[1,1-dimetil-propilamino]-1-hidroxi-metil}-2-hidroxi-fenil)-metansulfonamida y aplicaciones |
-
2005
- 2005-02-24 DE DE102005008921A patent/DE102005008921A1/de not_active Withdrawn
-
2006
- 2006-02-16 CA CA002598914A patent/CA2598914A1/en not_active Abandoned
- 2006-02-16 AU AU2006218010A patent/AU2006218010B2/en not_active Expired - Fee Related
- 2006-02-16 AT AT06708325T patent/ATE517877T1/de active
- 2006-02-16 DK DK06708325.3T patent/DK1856070T3/da active
- 2006-02-16 UA UAA200710494A patent/UA90504C2/ru unknown
- 2006-02-16 JP JP2007556591A patent/JP4950075B2/ja active Active
- 2006-02-16 BR BRPI0607258-5A patent/BRPI0607258A2/pt not_active IP Right Cessation
- 2006-02-16 WO PCT/EP2006/060033 patent/WO2006089859A1/de active Application Filing
- 2006-02-16 EP EP06708325A patent/EP1856070B1/de active Active
- 2006-02-16 PL PL06708325T patent/PL1856070T3/pl unknown
- 2006-02-16 CN CNA2006800060256A patent/CN101128444A/zh active Pending
- 2006-02-16 KR KR1020077021896A patent/KR20070110386A/ko not_active Application Discontinuation
- 2006-02-16 ES ES06708325T patent/ES2370653T3/es active Active
- 2006-02-16 MX MX2007010363A patent/MX2007010363A/es active IP Right Grant
- 2006-02-16 EA EA200701615A patent/EA012439B1/ru not_active IP Right Cessation
- 2006-02-16 NZ NZ561743A patent/NZ561743A/en not_active IP Right Cessation
- 2006-02-22 MY MYPI20060756A patent/MY146802A/en unknown
- 2006-02-22 PE PE2006000215A patent/PE20061097A1/es not_active Application Discontinuation
- 2006-02-23 US US11/276,307 patent/US20060189605A1/en not_active Abandoned
- 2006-02-23 TW TW095106149A patent/TWI369988B/zh not_active IP Right Cessation
- 2006-02-24 AR ARP060100674A patent/AR055562A1/es unknown
- 2006-02-24 UY UY29394A patent/UY29394A1/es not_active Application Discontinuation
-
2007
- 2007-06-14 ZA ZA200704727A patent/ZA200704727B/xx unknown
- 2007-06-22 NO NO20073176A patent/NO20073176L/no not_active Application Discontinuation
- 2007-08-22 IL IL185444A patent/IL185444A0/en unknown
-
2008
- 2008-12-18 US US12/338,333 patent/US20090105236A1/en not_active Abandoned
-
2010
- 2010-11-05 US US12/940,492 patent/US20110053926A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| UY29394A1 (es) | 2006-10-02 |
| US20110053926A1 (en) | 2011-03-03 |
| ES2370653T3 (es) | 2011-12-21 |
| AU2006218010A1 (en) | 2006-08-31 |
| DE102005008921A1 (de) | 2006-08-31 |
| IL185444A0 (en) | 2008-01-06 |
| ATE517877T1 (de) | 2011-08-15 |
| JP2008531518A (ja) | 2008-08-14 |
| WO2006089859A1 (de) | 2006-08-31 |
| DK1856070T3 (da) | 2011-09-26 |
| EP1856070A1 (de) | 2007-11-21 |
| JP4950075B2 (ja) | 2012-06-13 |
| ZA200704727B (en) | 2008-09-25 |
| US20090105236A1 (en) | 2009-04-23 |
| EP1856070B1 (de) | 2011-07-27 |
| CA2598914A1 (en) | 2006-08-31 |
| NO20073176L (no) | 2007-09-17 |
| TW200640465A (en) | 2006-12-01 |
| EA200701615A1 (ru) | 2008-02-28 |
| MY146802A (en) | 2012-09-28 |
| TWI369988B (en) | 2012-08-11 |
| CN101128444A (zh) | 2008-02-20 |
| UA90504C2 (ru) | 2010-05-11 |
| AU2006218010B2 (en) | 2013-02-14 |
| US20060189605A1 (en) | 2006-08-24 |
| NZ561743A (en) | 2009-09-25 |
| KR20070110386A (ko) | 2007-11-16 |
| MX2007010363A (es) | 2007-09-25 |
| BRPI0607258A2 (pt) | 2009-08-25 |
| PL1856070T3 (pl) | 2011-12-30 |
| EA012439B1 (ru) | 2009-10-30 |
| PE20061097A1 (es) | 2006-11-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |