AR055420A1 - Derivados de pirimidina sustituidos - Google Patents
Derivados de pirimidina sustituidosInfo
- Publication number
- AR055420A1 AR055420A1 ARP060103924A ARP060103924A AR055420A1 AR 055420 A1 AR055420 A1 AR 055420A1 AR P060103924 A ARP060103924 A AR P060103924A AR P060103924 A ARP060103924 A AR P060103924A AR 055420 A1 AR055420 A1 AR 055420A1
- Authority
- AR
- Argentina
- Prior art keywords
- alq
- ilo
- cycloalq
- yloxy
- halo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/50—Three nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200501262 | 2005-09-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR055420A1 true AR055420A1 (es) | 2007-08-22 |
Family
ID=37199174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060103924A AR055420A1 (es) | 2005-09-09 | 2006-09-08 | Derivados de pirimidina sustituidos |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1937653A1 (fr) |
| JP (1) | JP2009507052A (fr) |
| KR (1) | KR20080043314A (fr) |
| CN (1) | CN101258133A (fr) |
| AR (1) | AR055420A1 (fr) |
| AU (1) | AU2006322461A1 (fr) |
| BR (1) | BRPI0615631A2 (fr) |
| CA (1) | CA2621854A1 (fr) |
| EA (1) | EA200800780A1 (fr) |
| IL (1) | IL189545A0 (fr) |
| MX (1) | MX2008002294A (fr) |
| NO (1) | NO20081713L (fr) |
| UA (1) | UA93387C2 (fr) |
| WO (1) | WO2007065449A1 (fr) |
| ZA (1) | ZA200802174B (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2694887A1 (fr) * | 2007-08-01 | 2009-02-05 | Henriette Husum Bak-Jensen | Utilisation d'agents d'ouverture kncq des canaux potassiques pour reduire des symptomes ou traiter des troubles et des etats dans lesquels le systeme dopaminergique est detruit |
| US7786146B2 (en) * | 2007-08-13 | 2010-08-31 | Valeant Pharmaceuticals International | Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators |
| WO2010097379A1 (fr) * | 2009-02-24 | 2010-09-02 | Neurosearch A/S | Dérivés pyrimidine substitués et leur utilisation médicale |
| EP2590961A1 (fr) * | 2010-07-08 | 2013-05-15 | Pfizer Inc | Amides pipéridinyl pyrimidine en tant qu'ouvreurs du canal potassique ko7 |
| MX367623B (es) * | 2010-10-20 | 2019-08-29 | Gruenenthal Gmbh | 6-amino-nicotinamidas sustituidas como moduladores de kcnq2/3. |
| CN103508960B (zh) * | 2012-06-29 | 2017-12-12 | 江苏先声药业有限公司 | 苯并杂环衍生物 |
| CN103508943B (zh) * | 2012-06-29 | 2017-06-09 | 江苏先声药业有限公司 | 作为钾通道调节剂的化合物 |
| EP3210969B1 (fr) | 2014-10-24 | 2021-04-28 | ONO Pharmaceutical Co., Ltd. | Activateur des canaux kcnq2-5 |
| US20220280455A1 (en) * | 2019-08-02 | 2022-09-08 | H. Lundbeck A/S | Alcohol derivatives as kv7 potassium channel openers for use in epilepsy or seizures |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002066036A1 (fr) * | 2001-02-20 | 2002-08-29 | Bristol-Myers Squibb Company | Derives de 2,4-disubstitue pyrimidine-5-carboxamide en tant que modulateur des canaux potassium kcnq |
| WO2003068769A1 (fr) * | 2002-02-12 | 2003-08-21 | Pfizer Inc. | Composes non-peptidiques influant sur l'action de la gnrh |
| US20080261918A1 (en) * | 2004-12-17 | 2008-10-23 | Graham Andrew Showell | Silicon Compounds and Their Use |
-
2006
- 2006-09-07 WO PCT/DK2006/050039 patent/WO2007065449A1/fr active Application Filing
- 2006-09-07 UA UAA200803570A patent/UA93387C2/ru unknown
- 2006-09-07 CN CNA2006800327125A patent/CN101258133A/zh active Pending
- 2006-09-07 MX MX2008002294A patent/MX2008002294A/es active IP Right Grant
- 2006-09-07 AU AU2006322461A patent/AU2006322461A1/en not_active Abandoned
- 2006-09-07 CA CA002621854A patent/CA2621854A1/fr not_active Abandoned
- 2006-09-07 BR BRPI0615631-2A patent/BRPI0615631A2/pt not_active IP Right Cessation
- 2006-09-07 JP JP2008529473A patent/JP2009507052A/ja not_active Withdrawn
- 2006-09-07 EA EA200800780A patent/EA200800780A1/ru unknown
- 2006-09-07 ZA ZA200802174A patent/ZA200802174B/xx unknown
- 2006-09-07 EP EP06846967A patent/EP1937653A1/fr not_active Withdrawn
- 2006-09-07 KR KR1020087004306A patent/KR20080043314A/ko not_active Application Discontinuation
- 2006-09-08 AR ARP060103924A patent/AR055420A1/es not_active Application Discontinuation
-
2008
- 2008-02-14 IL IL189545A patent/IL189545A0/en unknown
- 2008-04-09 NO NO20081713A patent/NO20081713L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009507052A (ja) | 2009-02-19 |
| UA93387C2 (ru) | 2011-02-10 |
| BRPI0615631A2 (pt) | 2011-05-24 |
| AU2006322461A1 (en) | 2007-06-14 |
| KR20080043314A (ko) | 2008-05-16 |
| ZA200802174B (en) | 2009-10-28 |
| CN101258133A (zh) | 2008-09-03 |
| CA2621854A1 (fr) | 2007-06-14 |
| IL189545A0 (en) | 2008-06-05 |
| MX2008002294A (es) | 2008-03-14 |
| EP1937653A1 (fr) | 2008-07-02 |
| EA200800780A1 (ru) | 2008-06-30 |
| WO2007065449A1 (fr) | 2007-06-14 |
| NO20081713L (no) | 2008-06-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |