AR054808A1 - Composiciones que contienen particulas magneticas de oxido de hierro y uso de dichas composiciones en metodos de diagnostico por imagenes - Google Patents
Composiciones que contienen particulas magneticas de oxido de hierro y uso de dichas composiciones en metodos de diagnostico por imagenesInfo
- Publication number
- AR054808A1 AR054808A1 ARP060102810A ARP060102810A AR054808A1 AR 054808 A1 AR054808 A1 AR 054808A1 AR P060102810 A ARP060102810 A AR P060102810A AR P060102810 A ARP060102810 A AR P060102810A AR 054808 A1 AR054808 A1 AR 054808A1
- Authority
- AR
- Argentina
- Prior art keywords
- derivative
- compositions
- iron oxide
- coverage
- acceptable
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
- A61B5/418—Evaluating particular organs or parts of the immune or lymphatic systems lymph vessels, ducts or nodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/0515—Magnetic particle imaging
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
- A61B5/415—Evaluating particular organs or parts of the immune or lymphatic systems the glands, e.g. tonsils, adenoids or thymus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
- A61B5/416—Evaluating particular organs or parts of the immune or lymphatic systems the spleen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
- A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
- A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
- A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
- A61K49/1833—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with a small organic molecule
- A61K49/1836—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with a small organic molecule the small organic molecule being a carboxylic acid having less than 8 carbon atoms in the main chain
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
- A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
- A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
- A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
- A61K49/1851—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule
- A61K49/1863—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule the organic macromolecular compound being a polysaccharide or derivative thereof, e.g. chitosan, chitin, cellulose, pectin, starch
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
- A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
- A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
- A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
- A61K49/1866—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle the nanoparticle having a (super)(para)magnetic core coated or functionalised with a peptide, e.g. protein, polyamino acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
- A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
- A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
- A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
- A61K49/1875—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle coated or functionalised with an antibody
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Abstract
Complejos que contienen partículas magnéticas de oxido de hierro policristalino en una cobertura aceptable para uso farmacéutico, y al uso de dichas composiciones en el diagnostico por imágenes con partículas magnéticas (MPI). Se prefiere en particular el uso de dichas composiciones en exámenes del tracto gastrointestinal, del sistema vascular cardíaco y componentes craneanos, en el diagnostico de arteriosclerosis, infartos y tumores y metástasis, por ejemplo del sistema linfático. Reivindicacion 1: Una partícula caracterizada porque comprende, dentro de una cobertura aceptable para uso farmacéutico, un nucleo de oxido de hierro magnético policristalino con un diámetro entre 20 nm y 1 micron. Reivindicacion 3: Una partícula de acuerdo con la reivindicacion 1 o 2, caracterizada porque la cobertura aceptable para uso farmacéutico comprende un polímero o copolímero sintético, un almidon o un derivado del mismo, un dextrano o un derivado del mismo, un ciclodextrano o un derivado del mismo, un ácido graso, un polisacárido, una lecitina o un mono-, di- o triglicérido o un derivado del mismo o mezclas de los mismos. Reivindicacion 11:Un método para producir partículas que comprende, dentro de una cobertura aceptable para uso farmacéutico, un nucleo de oxido de hierro magnético policristalino con un diámetro entre 20 nm y 1micron, caracterizado porque dicho método comprende los siguientes pasos: ( i ) mezclar una solucion acuosa mixta de sales de hierro, que contiene una sal de hierro (II) y una sal de hierro (III), con una solucion alcalina acuosa en presencia de un polímero o copolímero sintético, un almidon o un derivado del mismo, un dextrano o un derivado del mismo, un ciclodextrano o un derivado del mismo, un ácido graso, un polisacárido, una lecitina o un mono-, di- o triglicérido o un derivado del mismo o mezclas de los mismos, hasta que se forma una suspension coloidal de las partículas, /ii) hacer pasar la solucion que contiene la partícula a través de un gradiente de campo magnético, (iii) quitar el gradiente de campo magnético, (iv) y recuperar las partículas retenidas en el gradiente de campo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05014058A EP1738773A1 (de) | 2005-06-29 | 2005-06-29 | Magnetische Eisenoxidpartikel enthaltende Zusammensetzung und deren Vervendung in bildgebenden Verfahren |
Publications (1)
Publication Number | Publication Date |
---|---|
AR054808A1 true AR054808A1 (es) | 2007-07-18 |
Family
ID=35432430
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP060102810A AR054808A1 (es) | 2005-06-29 | 2006-06-29 | Composiciones que contienen particulas magneticas de oxido de hierro y uso de dichas composiciones en metodos de diagnostico por imagenes |
Country Status (14)
Country | Link |
---|---|
US (2) | US20070014730A1 (es) |
EP (2) | EP1738773A1 (es) |
JP (1) | JP5366543B2 (es) |
CN (1) | CN101365495B (es) |
AR (1) | AR054808A1 (es) |
BR (1) | BRPI0611756A2 (es) |
DO (1) | DOP2006000154A (es) |
GT (1) | GT200600288A (es) |
PA (1) | PA8684201A1 (es) |
PE (1) | PE20070345A1 (es) |
RU (1) | RU2420319C2 (es) |
TW (1) | TW200800275A (es) |
UY (1) | UY29643A1 (es) |
WO (1) | WO2007000351A1 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1738774A1 (de) * | 2005-06-29 | 2007-01-03 | Schering AG | Magnetische Eisenoxidpartikel enthaltende Zusammensetzungen und deren Verwendung in bildgebenden Verfahren |
CN104042214A (zh) * | 2007-01-24 | 2014-09-17 | 皇家飞利浦电子股份有限公司 | 用于影响和/或探测作用区域中的磁性粒子的方法、磁性粒子以及磁性粒子的使用 |
JP2011516462A (ja) * | 2008-04-03 | 2011-05-26 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 磁性粒子イメージング用生体適合物 |
CN102348994A (zh) | 2009-03-09 | 2012-02-08 | 皇家飞利浦电子股份有限公司 | 用于测量作用区域中的磁性材料的设备和方法 |
KR101085824B1 (ko) * | 2009-03-11 | 2011-11-23 | 한국유나이티드제약 주식회사 | 생체적합성 고분자를 이용한 다기능성 조영제 및 이의 제조방법 |
WO2010128418A1 (en) | 2009-05-08 | 2010-11-11 | Koninklijke Philips Electronics N.V. | Arrangement and method for heating of a magnetic material |
WO2011001351A1 (en) * | 2009-07-01 | 2011-01-06 | Koninklijke Philips Electronics N. V. | Stimuli-responsive carriers for mpi-guided drug delivery |
WO2011030271A1 (en) * | 2009-09-14 | 2011-03-17 | Koninklijke Philips Electronics N.V. | Apparatus and method for moving and activating an active agent |
WO2011163136A2 (en) * | 2010-06-21 | 2011-12-29 | University of Washington Center for Commercialization | Tuned multifunctional magnetic nanoparticles for biomedicine |
US9555136B2 (en) | 2010-06-21 | 2017-01-31 | University Of Washington Through Its Center For Commercialization | Coated magnetic nanoparticles |
WO2012007871A1 (en) | 2010-07-13 | 2012-01-19 | Koninklijke Philips Electronics N.V. | System and method for generating a system function for use in the reconstruction of images |
RU2497546C1 (ru) * | 2012-04-23 | 2013-11-10 | Общество с ограниченной ответственностью "Ланда Фармасьютикалз" | Магнитно-резонансное и рентгеновское контрастное средство и способ его получения |
CN103316361B (zh) * | 2013-07-08 | 2015-04-01 | 武汉百仕康生物科技有限公司 | 一种稳定的纳米级超顺磁氧化铁溶液及其制备方法和应用 |
CN103704232B (zh) * | 2013-11-01 | 2016-01-06 | 北京科技大学 | 纳米农药羧甲基-β-环糊精-Fe3O4磁性纳米-敌草隆的制备方法 |
EP3081234B1 (en) * | 2013-12-13 | 2020-04-08 | Mercury Asset Management Co., Ltd. | Articular cartilage imaging composition |
US10898581B2 (en) * | 2014-01-16 | 2021-01-26 | The Brigham And Women's Hospital, Inc. | Targeted delivery of immunoregulatory drugs |
JP2019151552A (ja) * | 2016-07-12 | 2019-09-12 | 名糖産業株式会社 | 磁性粒子 |
KR20200017820A (ko) * | 2018-08-09 | 2020-02-19 | (주)아모레퍼시픽 | 미세먼지 제거용 다공성 복합분체 및 이의 제조방법 |
CN111298140B (zh) * | 2020-03-24 | 2022-04-19 | 中国科学院苏州纳米技术与纳米仿生研究所 | 还原响应的t1/t2切换型mri造影剂、其制备方法及应用 |
CN115125537B (zh) * | 2022-08-05 | 2023-04-11 | 四川轻化工大学 | 一种脱除聚晶金刚石复合片中钴的方法 |
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ATE179185T1 (de) * | 1992-08-05 | 1999-05-15 | Meito Sangyo Kk | Verbundmaterial mit kleinem durchmesser, welches ein wasserlösliches carboxylpolysaccharid und magnetisches eisenoxid enthaltet |
DE59403734D1 (de) * | 1993-03-17 | 1997-09-18 | Silica Gel Gmbh | Superparamagnetische teilchen, verfahren zu ihrer herstellung und verwendung derselben |
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US9808173B2 (en) * | 2003-04-15 | 2017-11-07 | Koninklijke Philips N.V. | Method for the spatially resolved determination of physcial, chemical and/or biological properties or state variables |
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US7747304B2 (en) * | 2003-04-15 | 2010-06-29 | Koninklijke Philips Electronics N.V. | Arrangement and method for the spatially resolved determination of state variables in an examination area |
CN1882364A (zh) * | 2003-11-17 | 2006-12-20 | 皇家飞利浦电子股份有限公司 | 用于医学成像技术的造影剂及其应用 |
EP1738774A1 (de) * | 2005-06-29 | 2007-01-03 | Schering AG | Magnetische Eisenoxidpartikel enthaltende Zusammensetzungen und deren Verwendung in bildgebenden Verfahren |
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2005
- 2005-06-29 EP EP05014058A patent/EP1738773A1/de not_active Withdrawn
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2006
- 2006-06-29 GT GT200600288A patent/GT200600288A/es unknown
- 2006-06-29 CN CN2006800234633A patent/CN101365495B/zh not_active Expired - Fee Related
- 2006-06-29 BR BRPI0611756-2A patent/BRPI0611756A2/pt not_active Application Discontinuation
- 2006-06-29 EP EP06762277A patent/EP1898960A1/en not_active Withdrawn
- 2006-06-29 US US11/476,913 patent/US20070014730A1/en not_active Abandoned
- 2006-06-29 AR ARP060102810A patent/AR054808A1/es not_active Application Discontinuation
- 2006-06-29 PA PA20068684201A patent/PA8684201A1/es unknown
- 2006-06-29 UY UY29643A patent/UY29643A1/es not_active Application Discontinuation
- 2006-06-29 TW TW095123566A patent/TW200800275A/zh unknown
- 2006-06-29 DO DO2006000154A patent/DOP2006000154A/es unknown
- 2006-06-29 US US11/476,934 patent/US20070036729A1/en not_active Abandoned
- 2006-06-29 JP JP2008518725A patent/JP5366543B2/ja not_active Expired - Fee Related
- 2006-06-29 WO PCT/EP2006/006320 patent/WO2007000351A1/en active Application Filing
- 2006-06-29 RU RU2008103203/15A patent/RU2420319C2/ru not_active IP Right Cessation
- 2006-07-03 PE PE2006000767A patent/PE20070345A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
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WO2007000351A1 (en) | 2007-01-04 |
EP1898960A1 (en) | 2008-03-19 |
US20070014730A1 (en) | 2007-01-18 |
CN101365495B (zh) | 2013-09-04 |
DOP2006000154A (es) | 2008-05-15 |
PE20070345A1 (es) | 2007-04-20 |
PA8684201A1 (es) | 2007-01-17 |
US20070036729A1 (en) | 2007-02-15 |
EP1738773A1 (de) | 2007-01-03 |
JP2008544968A (ja) | 2008-12-11 |
CN101365495A (zh) | 2009-02-11 |
TW200800275A (en) | 2008-01-01 |
RU2420319C2 (ru) | 2011-06-10 |
UY29643A1 (es) | 2007-01-31 |
RU2008103203A (ru) | 2009-08-10 |
JP5366543B2 (ja) | 2013-12-11 |
GT200600288A (es) | 2007-03-14 |
BRPI0611756A2 (pt) | 2012-04-17 |
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