AR053799A1 - Composiciones que contienen policonasol y teaflavina y sus usos farmaceuticos - Google Patents

Composiciones que contienen policonasol y teaflavina y sus usos farmaceuticos

Info

Publication number
AR053799A1
AR053799A1 ARP060100201A ARP060100201A AR053799A1 AR 053799 A1 AR053799 A1 AR 053799A1 AR P060100201 A ARP060100201 A AR P060100201A AR P060100201 A ARP060100201 A AR P060100201A AR 053799 A1 AR053799 A1 AR 053799A1
Authority
AR
Argentina
Prior art keywords
teaflavin
policosanol
diseases
drug
support layer
Prior art date
Application number
ARP060100201A
Other languages
English (en)
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of AR053799A1 publication Critical patent/AR053799A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

Abstract

Composicion que contiene policosanol y teaflavina y que puede usarse para tratar y/o reducir enfermedades hipercolesterolémicas, colesterol total, colesterol de LDL, enfermedad cardíaca coronaria (ataques al corazon y accidentes cerebrovasculares), inflamacion, trombosis venosa profunda, enfermedades inmunorregulatorias, enfermedades cardiovasculares y/o trastornos neurogenerativos en humanos y animales. El método comprende administrar policosanol y teaflavina, que juntos disminuyen efectivamente los niveles séricos de colesterol. Generalmente, la composicion administrada incluye una mezcla de aproximadamente 0,1-10:1 partes en peso de policosanol respecto de teaflavina. Reivindicacion 24: Un equipo que comprende un primer contenedor que comprende una formulacion de liberacion controlada de policosanol y teaflavina en una cantidad efectiva para tratar o reducir y/o prevenir enfermedades hipercolesterolémicas, colesterol total, colesterol de LDL, enfermedad cardíaca coronaria (ataques al corazon y accidentes cerebrovasculares), inflamacion, enfermedades inmunorregulatorias, enfermedades cardiovasculares y/o trastornos neurodegenerativos. Reivindicacion 25: El equipo de la reivindicacion 24, que además comprende una aguja para puncion o un catéter. Reivindicacion 26: Un artículo de fabricacion que comprende: un cuerpo de endoprotesis vascular (stent) que comprende una superficie; y un recubrimiento que comprende por lo menos una capa dispuesta sobre por lo menos una parte del cuerpo de la endoprotesis vascular, en donde dicha capa comprende una película de polímero que tiene policosanol y teaflavina dispersos en ella. Reivindicacion 36: Un sistema de administracion transdérmica para aplicar a la piel de un paciente, que comprende: a) una capa de soporte impermeable a la droga; b) una capa adhesiva; c) una membrana permeable a la droga, en donde la membrana se coloca en relacion a la capa de soporte de modo tal de formar por lo menos un reservorio para la droga entre la membrana y la capa de soporte; y d) una composicion que comprende policosanol y teaflavina contenida dentro del reservorio de droga en una concentracion suficiente para que el sistema de administracion transdérmica tenga una velocidad de entrada cuando se aplica a la piel suficiente para producir una concentracion plásmica en estado de equilibrio farmacéuticamente efectiva de policosanol y teaflavina en el paciente. Reivindicacion 38: Un implante subcutáneo que comprende policosanol y teaflavina.
ARP060100201A 2005-01-20 2006-01-19 Composiciones que contienen policonasol y teaflavina y sus usos farmaceuticos AR053799A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64554805P 2005-01-20 2005-01-20

Publications (1)

Publication Number Publication Date
AR053799A1 true AR053799A1 (es) 2007-05-23

Family

ID=36284786

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060100201A AR053799A1 (es) 2005-01-20 2006-01-19 Composiciones que contienen policonasol y teaflavina y sus usos farmaceuticos

Country Status (4)

Country Link
AR (1) AR053799A1 (es)
PE (1) PE20060862A1 (es)
TW (1) TW200637536A (es)
WO (1) WO2006078600A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090156662A1 (en) * 2006-04-26 2009-06-18 Ito En, Ltd. Fat Absorption Inhibitor
US9861590B2 (en) 2010-10-19 2018-01-09 Covidien Lp Self-supporting films for delivery of therapeutic agents
WO2020218755A1 (ko) * 2019-04-25 2020-10-29 ㈜아모레퍼시픽 테아플라빈을 포함하는 지방세포 분화 촉진용 조성물
KR102359446B1 (ko) * 2019-04-25 2022-02-09 (주)아모레퍼시픽 테아플라빈을 포함하는 지방세포 분화 촉진용 조성물
CN112915077A (zh) * 2021-02-18 2021-06-08 南昌大学附属口腔医院(江西省口腔医院) 一种口腔酸蚀剂及其制备方法、应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7157493B2 (en) * 2001-11-28 2007-01-02 Nashai Biotech, Llc Methods of making and using theaflavin, theaflavin-3-gallate, theaflavin-3′-gallate and theaflavin 3,3′-digallate and mixtures thereof
US6565896B1 (en) * 2002-07-03 2003-05-20 Vitacost.Com, Inc. Cholesterol treatment formulation
US20040097432A1 (en) * 2002-11-04 2004-05-20 Access Business Group International Llc. Method of reducing cholesterol
US20040202732A1 (en) * 2003-04-11 2004-10-14 Brown William Stewart Composition to promote weight loss

Also Published As

Publication number Publication date
PE20060862A1 (es) 2006-10-13
TW200637536A (en) 2006-11-01
WO2006078600A1 (en) 2006-07-27

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