AR045996A1 - Formulaciones semi-solidas para la administracion oral de taxoides - Google Patents
Formulaciones semi-solidas para la administracion oral de taxoidesInfo
- Publication number
- AR045996A1 AR045996A1 ARP040102493A ARP040102493A AR045996A1 AR 045996 A1 AR045996 A1 AR 045996A1 AR P040102493 A ARP040102493 A AR P040102493A AR P040102493 A ARP040102493 A AR P040102493A AR 045996 A1 AR045996 A1 AR 045996A1
- Authority
- AR
- Argentina
- Prior art keywords
- semi
- taxoids
- oral administration
- solid formulations
- mixture
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 239000007787 solid Substances 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- AOBORMOPSGHCAX-UHFFFAOYSA-N Tocophersolan Chemical compound OCCOC(=O)CCC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C AOBORMOPSGHCAX-UHFFFAOYSA-N 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000008240 homogeneous mixture Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000012439 solid excipient Substances 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03291795A EP1498120A1 (en) | 2003-07-18 | 2003-07-18 | Semi-solid formulations for the oral administration of taxoids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR045996A1 true AR045996A1 (es) | 2005-11-23 |
Family
ID=33462258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP040102493A AR045996A1 (es) | 2003-07-18 | 2004-07-15 | Formulaciones semi-solidas para la administracion oral de taxoides |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20050070496A1 (enExample) |
| EP (2) | EP1498120A1 (enExample) |
| JP (1) | JP5116306B2 (enExample) |
| KR (1) | KR101143341B1 (enExample) |
| CN (1) | CN1826110B (enExample) |
| AR (1) | AR045996A1 (enExample) |
| AT (1) | ATE388701T1 (enExample) |
| AU (1) | AU2004262496B2 (enExample) |
| BR (1) | BRPI0412759A (enExample) |
| CA (1) | CA2532667A1 (enExample) |
| DE (1) | DE602004012413T2 (enExample) |
| DK (1) | DK1648440T3 (enExample) |
| ES (1) | ES2303642T3 (enExample) |
| IL (1) | IL173110A (enExample) |
| IN (1) | IN229997B (enExample) |
| MX (1) | MX260260B (enExample) |
| MY (1) | MY137965A (enExample) |
| PT (1) | PT1648440E (enExample) |
| TW (1) | TWI342774B (enExample) |
| WO (1) | WO2005013968A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1498143A1 (en) * | 2003-07-18 | 2005-01-19 | Aventis Pharma S.A. | Self-emulsifying and self-microemulsifying formulations for the oral administration of taxoids |
| JP2009538317A (ja) * | 2006-05-26 | 2009-11-05 | バイエル ヘルスケア リミティド ライアビリティ カンパニー | 癌治療のための置換ジアリールウレアを用いた薬物の組み合わせ |
| FR2922107B1 (fr) * | 2007-10-10 | 2010-02-26 | Aventis Pharma Sa | Nouvelles compositions a base de taxoides |
| FR2924024B1 (fr) | 2007-11-27 | 2012-08-17 | Centre Nat Rech Scient | Nanoparticules d'actifs therapeutiques de faible solubilite aqueuse |
| FR2931152B1 (fr) * | 2008-05-16 | 2010-07-30 | Centre Nat Rech Scient | Nouveau systeme de transfert d'acide nucleique |
| PL2493466T3 (pl) | 2009-10-29 | 2021-11-15 | Sanofi Mature Ip | Nowe przeciwguzowe zastosowanie kabazytakselu |
| EP2566474B1 (en) | 2010-05-03 | 2017-11-15 | Teikoku Pharma USA, Inc. | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
| JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
| CN103980232A (zh) * | 2014-06-05 | 2014-08-13 | 北京诺普德医药科技有限公司 | 10-乙酰基多西紫杉醇及其用途 |
| KR101542364B1 (ko) * | 2014-10-31 | 2015-08-07 | 대화제약 주식회사 | 탁산을 포함하는 경구 투여용 약학 조성물 |
| CN113698369A (zh) * | 2021-08-31 | 2021-11-26 | 无锡紫杉药业有限公司 | 一种除去卡巴他赛中特定单杂的方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3406497A1 (de) * | 1984-02-23 | 1985-09-05 | Mueller Bernhard Willi Werner | Hochdisperse pharmazeutische mehrkomponentensysteme und verfahren zu ihrer herstellung |
| US5272171A (en) * | 1992-02-13 | 1993-12-21 | Bristol-Myers Squibb Company | Phosphonooxy and carbonate derivatives of taxol |
| JP3208517B2 (ja) * | 1992-07-01 | 2001-09-17 | ブリストル−マイヤーズ スクイブ カンパニー | ７，８−シクロプロパタキサン類 |
| US5254580A (en) * | 1993-01-19 | 1993-10-19 | Bristol-Myers Squibb Company | 7,8-cyclopropataxanes |
| US5294637A (en) * | 1992-07-01 | 1994-03-15 | Bristol-Myers Squibb Company | Fluoro taxols |
| US5478854A (en) * | 1992-10-01 | 1995-12-26 | Bristol-Myers Squibb Company | Deoxy taxols |
| US5973160A (en) * | 1992-12-23 | 1999-10-26 | Poss; Michael A. | Methods for the preparation of novel sidechain-bearing taxanes |
| US5646176A (en) * | 1992-12-24 | 1997-07-08 | Bristol-Myers Squibb Company | Phosphonooxymethyl ethers of taxane derivatives |
| US6054136A (en) * | 1993-09-30 | 2000-04-25 | Gattefosse S.A. | Orally administrable composition capable of providing enhanced bioavailability when ingested |
| US6458373B1 (en) * | 1997-01-07 | 2002-10-01 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
| IL131217A0 (en) * | 1998-03-10 | 2001-01-28 | Napro Biotherapeutics Inc | Novel methods and compositions for delivery of taxanes |
| EP1067908B9 (en) * | 1998-04-01 | 2007-01-24 | Jagotec Ag | Taxane microemulsions |
| EP1185301A1 (en) * | 1999-05-24 | 2002-03-13 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
| US6136846A (en) * | 1999-10-25 | 2000-10-24 | Supergen, Inc. | Formulation for paclitaxel |
| JP2004520398A (ja) * | 2001-01-18 | 2004-07-08 | ファルマシア・アンド・アップジョン・カンパニー | 経口生物学的利用能が改善されたパクリタキセルの化学療法マイクロエマルジョン組成物 |
| WO2003045357A1 (en) * | 2001-11-27 | 2003-06-05 | Transform Pharmaceuticals, Inc. | Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof |
| AU2002361701A1 (en) * | 2001-12-20 | 2003-07-09 | Bristol-Myers Squibb Company | Pharmaceutical compositons of orally active taxane derivatives having enhanced bioavailability |
| ATE359779T1 (de) * | 2002-03-01 | 2007-05-15 | Novagali Pharma Sa | Selbstemulgierende systeme zur abgabe von taxoiden |
| KR20090072980A (ko) * | 2007-12-28 | 2009-07-02 | 서울옵토디바이스주식회사 | 발광 다이오드 및 그 제조방법 |
-
2003
- 2003-07-18 EP EP03291795A patent/EP1498120A1/en not_active Ceased
-
2004
- 2004-07-15 KR KR1020067001136A patent/KR101143341B1/ko not_active Expired - Fee Related
- 2004-07-15 CA CA002532667A patent/CA2532667A1/en not_active Abandoned
- 2004-07-15 DE DE602004012413T patent/DE602004012413T2/de not_active Expired - Lifetime
- 2004-07-15 CN CN2004800207228A patent/CN1826110B/zh not_active Expired - Fee Related
- 2004-07-15 WO PCT/EP2004/008551 patent/WO2005013968A1/en not_active Ceased
- 2004-07-15 ES ES04741331T patent/ES2303642T3/es not_active Expired - Lifetime
- 2004-07-15 PT PT04741331T patent/PT1648440E/pt unknown
- 2004-07-15 MX MXPA06000636 patent/MX260260B/es active IP Right Grant
- 2004-07-15 BR BRPI0412759-5A patent/BRPI0412759A/pt not_active IP Right Cessation
- 2004-07-15 AU AU2004262496A patent/AU2004262496B2/en not_active Ceased
- 2004-07-15 JP JP2006519899A patent/JP5116306B2/ja not_active Expired - Fee Related
- 2004-07-15 AR ARP040102493A patent/AR045996A1/es not_active Application Discontinuation
- 2004-07-15 AT AT04741331T patent/ATE388701T1/de not_active IP Right Cessation
- 2004-07-15 IN IN198CH2006 patent/IN229997B/en unknown
- 2004-07-15 DK DK04741331T patent/DK1648440T3/da active
- 2004-07-15 EP EP04741331A patent/EP1648440B1/en not_active Expired - Lifetime
- 2004-07-16 TW TW093121233A patent/TWI342774B/zh not_active IP Right Cessation
- 2004-07-16 MY MYPI20042868A patent/MY137965A/en unknown
- 2004-07-19 US US10/894,163 patent/US20050070496A1/en not_active Abandoned
-
2006
- 2006-01-12 IL IL173110A patent/IL173110A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1826110A (zh) | 2006-08-30 |
| IN2006CH00198A (enExample) | 2007-06-08 |
| CA2532667A1 (en) | 2005-02-17 |
| WO2005013968A1 (en) | 2005-02-17 |
| MXPA06000636A (es) | 2006-04-19 |
| AU2004262496A1 (en) | 2005-02-17 |
| PT1648440E (pt) | 2008-06-24 |
| ATE388701T1 (de) | 2008-03-15 |
| AU2004262496B2 (en) | 2009-02-05 |
| DE602004012413D1 (de) | 2008-04-24 |
| CN1826110B (zh) | 2010-05-12 |
| TWI342774B (en) | 2011-06-01 |
| JP2009513558A (ja) | 2009-04-02 |
| HK1091743A1 (zh) | 2007-01-26 |
| IN229997B (enExample) | 2009-03-27 |
| KR101143341B1 (ko) | 2012-05-24 |
| MX260260B (es) | 2008-09-04 |
| IL173110A0 (en) | 2006-06-11 |
| KR20060037370A (ko) | 2006-05-03 |
| BRPI0412759A (pt) | 2006-09-26 |
| EP1648440B1 (en) | 2008-03-12 |
| MY137965A (en) | 2009-04-30 |
| EP1648440A1 (en) | 2006-04-26 |
| IL173110A (en) | 2011-04-28 |
| DE602004012413T2 (de) | 2009-03-12 |
| TW200517104A (en) | 2005-06-01 |
| EP1498120A1 (en) | 2005-01-19 |
| JP5116306B2 (ja) | 2013-01-09 |
| ES2303642T3 (es) | 2008-08-16 |
| DK1648440T3 (da) | 2008-07-14 |
| US20050070496A1 (en) | 2005-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal | ||
| FB | Suspension of granting procedure |