AR044826A1 - Sales derivadas del acido propionico,y su uso medicinal - Google Patents

Sales derivadas del acido propionico,y su uso medicinal

Info

Publication number
AR044826A1
AR044826A1 ARP040102136A ARP040102136A AR044826A1 AR 044826 A1 AR044826 A1 AR 044826A1 AR P040102136 A ARP040102136 A AR P040102136A AR P040102136 A ARP040102136 A AR P040102136A AR 044826 A1 AR044826 A1 AR 044826A1
Authority
AR
Argentina
Prior art keywords
salt
salts derived
propionic acid
satiated
ethyl
Prior art date
Application number
ARP040102136A
Other languages
English (en)
Inventor
Matti Ahiqvist
Mikael Dahistrom
Bengt Ohlsson
Richard Storey
Nigel Taylor
Rebecca Woods
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR044826A1 publication Critical patent/AR044826A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Sales derivadas del ácido propionico, su uso en el tratamiento de afecciones clínicas incluyendo trastornos en los lípidos (dislipidemias) saciados o no con la resistencia a la insulina y otras manifestaciones del síndrome metabólico, y composiciones farmacéuticas que los contienen. Reivindicación 1: Una sal de tert-butilamina, una sal de piperazina, una sal de colina, una sal de tris(hidroximetil)metil-amina, una sal de lisina o una sal de adamantina de ácido (-)-2-{[2-(4-hidroxifenil)etil]tio}-3-[4-(2-{4-[(metilsulfonil)oxi]fenoxi}etil)fenil]propanoico.
ARP040102136A 2003-06-18 2004-06-18 Sales derivadas del acido propionico,y su uso medicinal AR044826A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0314130.6A GB0314130D0 (en) 2003-06-18 2003-06-18 Therapeutic agents

Publications (1)

Publication Number Publication Date
AR044826A1 true AR044826A1 (es) 2005-10-05

Family

ID=27636789

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040102136A AR044826A1 (es) 2003-06-18 2004-06-18 Sales derivadas del acido propionico,y su uso medicinal

Country Status (20)

Country Link
US (1) US20070099928A1 (es)
EP (1) EP1638930A1 (es)
JP (1) JP3927594B2 (es)
KR (1) KR20060023165A (es)
CN (1) CN1835919A (es)
AR (1) AR044826A1 (es)
AU (1) AU2004249483A1 (es)
BR (1) BRPI0411580A (es)
CA (1) CA2529544A1 (es)
CO (1) CO5630026A2 (es)
GB (1) GB0314130D0 (es)
IL (1) IL172633A0 (es)
IS (1) IS8224A (es)
MX (1) MXPA05013718A (es)
NO (1) NO20056006L (es)
RU (1) RU2005141061A (es)
TW (1) TW200503671A (es)
UY (1) UY28372A1 (es)
WO (1) WO2004113283A1 (es)
ZA (1) ZA200510263B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0104333D0 (sv) * 2001-12-19 2001-12-19 Astrazeneca Ab Therapeutic agents
WO2004000790A1 (en) 2002-06-20 2003-12-31 Astrazeneca Ab Ortho-substituted benzoic acid derivatives for the treatment of insulin resistance
GB0314131D0 (en) * 2003-06-18 2003-07-23 Astrazeneca Ab Therapeutic agents
GB0314075D0 (en) * 2003-06-18 2003-07-23 Astrazeneca Ab Therapeutic agents
GB0427524D0 (en) 2004-12-16 2005-01-19 Astrazeneca Ab Chemical process
GB0427701D0 (en) * 2004-12-17 2005-01-19 Astrazeneca Ab Therapeutic agents
MX2009007670A (es) * 2007-01-18 2011-11-18 Evolva Sa 1,3-dioxanos sustituidos utiles como moduladores de paar.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9801992D0 (sv) * 1998-06-04 1998-06-04 Astra Ab New 3-aryl-2-hydroxypropionic acid derivative I
MA26634A1 (fr) * 1998-06-04 2004-12-20 Astra Ab Nouveaux derives de l'acide 3-aryl propionique et analogues
SE0104333D0 (sv) * 2001-12-19 2001-12-19 Astrazeneca Ab Therapeutic agents

Also Published As

Publication number Publication date
BRPI0411580A (pt) 2006-08-08
IS8224A (is) 2006-01-10
CO5630026A2 (es) 2006-04-28
TW200503671A (en) 2005-02-01
EP1638930A1 (en) 2006-03-29
GB0314130D0 (en) 2003-07-23
UY28372A1 (es) 2005-01-31
CA2529544A1 (en) 2004-12-29
AU2004249483A1 (en) 2004-12-29
NO20056006L (no) 2006-02-24
CN1835919A (zh) 2006-09-20
WO2004113283A1 (en) 2004-12-29
IL172633A0 (en) 2006-04-10
KR20060023165A (ko) 2006-03-13
RU2005141061A (ru) 2006-08-27
MXPA05013718A (es) 2006-06-27
JP3927594B2 (ja) 2007-06-13
JP2006527749A (ja) 2006-12-07
ZA200510263B (en) 2007-02-28
US20070099928A1 (en) 2007-05-03

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal