AR037814A1 - 6h-dibenzo[c,h]cromenos sustituidos como agentes estrogenicos - Google Patents
6h-dibenzo[c,h]cromenos sustituidos como agentes estrogenicosInfo
- Publication number
- AR037814A1 AR037814A1 ARP020104830A ARP020104830A AR037814A1 AR 037814 A1 AR037814 A1 AR 037814A1 AR P020104830 A ARP020104830 A AR P020104830A AR P020104830 A ARP020104830 A AR P020104830A AR 037814 A1 AR037814 A1 AR 037814A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- halogen
- alkenyl
- hydroxyl
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Neurology (AREA)
- Gynecology & Obstetrics (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Communicable Diseases (AREA)
- Toxicology (AREA)
- Pain & Pain Management (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
Abstract
Moduladores del receptor de estrógeno de la fórmula (1). Reivindicación 1: Un compuesto de la fórmula (1), en la cual: cada uno de R1 y R2 es, independientemente seleccionado entre H, hidroxilo, alquilo C1-6, alquenilo C2-6, alquinilo C2-7, alcoxi C1-6 o halógeno, donde las porciones alquilo o alquenilo de R1 o R2 pueden estar optativamente sustituidas con hidroxilo, -CN, halógeno, trifluoralquilo, trifluoralcoxi, -NO2 o fenilo; y siempre que por lo menos uno de R1 o R2 sea hidroxilo; cada uno de R3, R4, R5, R6 y R7 es, independientemente, H, alquilo C1-6, halógeno, alcoxi C1-6, -CN, alquenilo C2-7, alquinilo C2-7, -CHO, fenilo o un anillo heterocíclico de 5 ó 6 miembros con 1 a 4 heteroátomos seleccionados entre O, N ó S, donde las porciones alquilo o alquenilo de R4, R5, R6 o R7 pueden estar optativamente sustituidas con hidroxilo, -CN, halógeno, trifluoralquilo, trifluoralcoxi, -NO2 o fenilo; donde la porción fenilo de R4 o R5 puede estar optativamente mono-, di- o trisustituida con alquilo C1-6, alquenilo C2-7, halógeno, hidroxilo, alcoxi C1-6, -CN, NO2, amino, alquilamino C1-6, dialquilamino C1-6 por grupo alquilo, tio, alquiltio C1-6, alquilsulfinilo C1-6, alquilsulfonilo C1-6 alcoxicarbonilo C2-7, alquilcarbonilo C2-7 o benzoílo; o una sal farmacéuticamente aceptable del mismo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34144101P | 2001-12-13 | 2001-12-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR037814A1 true AR037814A1 (es) | 2004-12-09 |
Family
ID=23337586
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP020104830A AR037814A1 (es) | 2001-12-13 | 2002-12-12 | 6h-dibenzo[c,h]cromenos sustituidos como agentes estrogenicos |
Country Status (16)
Country | Link |
---|---|
US (1) | US6723747B2 (es) |
EP (1) | EP1453820B1 (es) |
JP (1) | JP2005538925A (es) |
CN (1) | CN100429210C (es) |
AR (1) | AR037814A1 (es) |
AT (1) | ATE296818T1 (es) |
AU (1) | AU2002357184A1 (es) |
BR (1) | BR0214918A (es) |
CA (1) | CA2470105C (es) |
DE (1) | DE60204482T2 (es) |
ES (1) | ES2240856T3 (es) |
HK (1) | HK1069171A1 (es) |
MX (1) | MXPA04005630A (es) |
PT (1) | PT1453820E (es) |
TW (1) | TW200301107A (es) |
WO (1) | WO2003051863A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005014586A1 (en) | 2003-08-08 | 2005-02-17 | Arpida Ag | Novel process for the preparation of 2h-chromenes |
US7157492B2 (en) * | 2004-02-26 | 2007-01-02 | Wyeth | Dibenzo chromene derivatives and their use as ERβ selective ligands |
AU2005262385A1 (en) * | 2004-07-01 | 2006-01-19 | Wyeth | Tetracyclic compounds as estrogen ligands |
AU2005282554A1 (en) | 2004-09-07 | 2006-03-16 | Wyeth | 6H-[1]benzopyrano[4,3-b]quinolines and their use as estrogenic agents |
CN101321524A (zh) * | 2004-12-17 | 2008-12-10 | 惠氏公司 | 雌激素β激动剂的新用途 |
JP2008530210A (ja) * | 2005-02-16 | 2008-08-07 | ワイス | 放射線または化学療法誘発粘膜炎および放射線膀胱炎のためのエストロゲン受容体−β選択性アゴニストの使用 |
AU2007215131A1 (en) * | 2006-02-14 | 2007-08-23 | Wyeth | Aqueous pharmaceutical formulations of ERbeta selective ligands |
WO2008091555A2 (en) | 2007-01-22 | 2008-07-31 | Gtx, Inc. | Nuclear receptor binding agents |
US9623021B2 (en) * | 2007-01-22 | 2017-04-18 | Gtx, Inc. | Nuclear receptor binding agents |
US9604931B2 (en) | 2007-01-22 | 2017-03-28 | Gtx, Inc. | Nuclear receptor binding agents |
WO2008094976A2 (en) * | 2007-01-31 | 2008-08-07 | Wyeth | Use of estrogen receptor beta selective ligands for treating acute lung injuries |
CN108774207B (zh) * | 2018-07-30 | 2021-12-17 | 苏州大学张家港工业技术研究院 | 环戊二烯并[c]色烯化合物及其制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5688810A (en) | 1994-12-22 | 1997-11-18 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
EP1382597A3 (en) * | 1994-12-22 | 2004-04-07 | Ligand Pharmaceuticals, Inc. | Steroid receptor modulator compounds and methods |
CN1358091A (zh) | 1999-04-16 | 2002-07-10 | 阿斯特拉曾尼卡有限公司 | 雌激素受体-β配体 |
-
2002
- 2002-12-10 TW TW091135700A patent/TW200301107A/zh unknown
- 2002-12-11 US US10/317,163 patent/US6723747B2/en not_active Expired - Fee Related
- 2002-12-12 DE DE60204482T patent/DE60204482T2/de not_active Expired - Lifetime
- 2002-12-12 AT AT02805117T patent/ATE296818T1/de not_active IP Right Cessation
- 2002-12-12 EP EP02805117A patent/EP1453820B1/en not_active Expired - Lifetime
- 2002-12-12 CA CA2470105A patent/CA2470105C/en not_active Expired - Fee Related
- 2002-12-12 JP JP2003552747A patent/JP2005538925A/ja not_active Ceased
- 2002-12-12 PT PT02805117T patent/PT1453820E/pt unknown
- 2002-12-12 BR BRPI0214918-4A patent/BR0214918A/pt not_active IP Right Cessation
- 2002-12-12 MX MXPA04005630A patent/MXPA04005630A/es active IP Right Grant
- 2002-12-12 ES ES02805117T patent/ES2240856T3/es not_active Expired - Lifetime
- 2002-12-12 AR ARP020104830A patent/AR037814A1/es not_active Application Discontinuation
- 2002-12-12 WO PCT/US2002/039802 patent/WO2003051863A1/en active IP Right Grant
- 2002-12-12 AU AU2002357184A patent/AU2002357184A1/en not_active Abandoned
- 2002-12-12 CN CNB028248791A patent/CN100429210C/zh not_active Expired - Fee Related
-
2005
- 2005-02-28 HK HK05101682A patent/HK1069171A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE60204482D1 (de) | 2005-07-07 |
AU2002357184A1 (en) | 2003-06-30 |
CA2470105A1 (en) | 2003-06-26 |
BR0214918A (pt) | 2006-05-30 |
WO2003051863A1 (en) | 2003-06-26 |
EP1453820B1 (en) | 2005-06-01 |
CA2470105C (en) | 2010-07-27 |
ES2240856T3 (es) | 2005-10-16 |
JP2005538925A (ja) | 2005-12-22 |
US6723747B2 (en) | 2004-04-20 |
US20030176491A1 (en) | 2003-09-18 |
DE60204482T2 (de) | 2005-10-27 |
CN100429210C (zh) | 2008-10-29 |
CN1602307A (zh) | 2005-03-30 |
HK1069171A1 (en) | 2005-05-13 |
TW200301107A (en) | 2003-07-01 |
ATE296818T1 (de) | 2005-06-15 |
PT1453820E (pt) | 2005-09-30 |
EP1453820A1 (en) | 2004-09-08 |
MXPA04005630A (es) | 2004-12-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR038019A1 (es) | Naftalenos substituidos con fenilo como agentes estrogenicos | |
AR054799A1 (es) | Derivados de oxindol | |
AR037814A1 (es) | 6h-dibenzo[c,h]cromenos sustituidos como agentes estrogenicos | |
PE20070181A1 (es) | DERIVADOS DE CICLOHEXILAMINISOQUINOLONA COMO INHIBIDORES DE Rho-QUINASA | |
AR054214A1 (es) | Compuestos derivados de 1, 1 - dioxotiadiazina, composiciones farmaceuticas que los contienen y su uso en el tratamiento de la infeccion por el virus de la hepatitis c. | |
ECSP034865A (es) | Resolución óptica de (1-benzilo-4-metilopiperidina-3-il)-metilamina y su uso para la preparación de derivados de pirrolo 2,3-pirimidina como inhibidores de proteina quinasas | |
PE20060691A1 (es) | Serinamidas sustituidas por benzoilo | |
AR055592A1 (es) | Derivados de 2-amino-5-cicloalquil-hidantoina como moduladores y/o inhibidores de la beta-secretasa(bace) | |
AR047538A1 (es) | Piridazinonas como antagonistas de las integrinas alfa4 | |
AR053569A1 (es) | Derivados de pirazol | |
AR058587A1 (es) | Compuestos de pirrolo-1,5-naftiridinona,su uso como agentes antibacterianos, composiciones farmaceuticas que los contienen y compuestos intermediarios para preparar dichos compuestos | |
AR043038A1 (es) | Compuestos de pirazolotriazina y usos de los mismos | |
AR048315A1 (es) | Compuestos heterociclicos inhibidores de la produccion de citocinas; composiciones farmaceuticas que los contienen y su uso en el tratamiento de enfermedades inflamatorias y oncologicas. | |
PE20050664A1 (es) | Derivados de 1h-imidazo[4,5-c]quinolina | |
AR049126A1 (es) | Derivados de 5, 6, 7, 8 - tetrahidroimidazo[1,5a]piridina con actividad inhibitoria de la aldosterona sintasa, composiciones farmaceuticas que los contienen y su uso en la preparacion de medicamentos para el tratamiento del hiperaldosterismo y del sindrome de cushing. | |
AR056686A1 (es) | Derivados de diacilindazol como inhibidores de lipasas y fosfolipasas | |
PE20061106A1 (es) | Derivados de 2-(4-oxo-4h-quinazolin-3-il)acetamida | |
AR053774A1 (es) | Derivados de sulfonilbencimidazol. composiciones farmaceuticas. | |
AR049646A1 (es) | Derivados de sulfamato y sulfamida utiles para el tratamiento de la epilepsia y trastornos relacionados | |
AR029215A1 (es) | Derivados de benzazol y tautomeros de los mismos utiles en el tratamiento de desordenes en los sistemas de autoinmunidad y neuronales, uso de dichos derivados en la preparacion de composiciones farmaceuticas aplicables en el tratamiento de dichos desordenes, metodo prar inhibir la expresion y/o acti | |
AR067569A1 (es) | Procedimiento para la modulacion del receptor acoplado a la proteina g gpr 119 y compuestos seleccionados | |
PE20080841A1 (es) | Derivados de quinazolinona e isoquinolinona y su uso para el tratamiento o prevencion de trastornos relacionados con el estres o la depresion | |
PE20060531A1 (es) | Derivados de piridazin-3-(2h)-ona como inhibidores de la fosfodiesterasa 4 | |
AR078408A1 (es) | Derivados de indol como moduladores de los crac | |
PE20080182A1 (es) | Derivados pirrolo-quinoxalinona como antibacterianos |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |