AR037642A1 - Preformulacion farmaceutica para tabletado, y procedimiento para su preparacion - Google Patents
Preformulacion farmaceutica para tabletado, y procedimiento para su preparacionInfo
- Publication number
- AR037642A1 AR037642A1 ARP020104698A ARP020104698A AR037642A1 AR 037642 A1 AR037642 A1 AR 037642A1 AR P020104698 A ARP020104698 A AR P020104698A AR P020104698 A ARP020104698 A AR P020104698A AR 037642 A1 AR037642 A1 AR 037642A1
- Authority
- AR
- Argentina
- Prior art keywords
- preformulation
- dry extract
- pharmaceutical
- conjugated
- estrogens
- Prior art date
Links
- 239000000203 mixture Substances 0.000 abstract 4
- 239000007787 solid Substances 0.000 abstract 4
- 241000283073 Equus caballus Species 0.000 abstract 3
- 229940011871 estrogen Drugs 0.000 abstract 3
- 239000000262 estrogen Substances 0.000 abstract 3
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 2
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 229940035811 conjugated estrogen Drugs 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 230000003054 hormonal effect Effects 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000003981 vehicle Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01129840 | 2001-12-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR037642A1 true AR037642A1 (es) | 2004-11-17 |
Family
ID=8179550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP020104698A AR037642A1 (es) | 2001-12-14 | 2002-12-04 | Preformulacion farmaceutica para tabletado, y procedimiento para su preparacion |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8273728B2 (https=) |
| EP (1) | EP1458363B1 (https=) |
| JP (1) | JP4695838B2 (https=) |
| CN (2) | CN1298313C (https=) |
| AR (1) | AR037642A1 (https=) |
| AU (1) | AU2002358682B2 (https=) |
| BR (1) | BR0214954A (https=) |
| CA (1) | CA2470209A1 (https=) |
| ES (1) | ES2403218T3 (https=) |
| MX (1) | MXPA04005767A (https=) |
| PL (1) | PL205544B1 (https=) |
| TW (1) | TWI332400B (https=) |
| WO (1) | WO2003051337A1 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9586335B2 (en) * | 2010-01-27 | 2017-03-07 | Sd3, Llc | Blade guard with dust collection |
| TWI332400B (en) * | 2001-12-14 | 2010-11-01 | Solvay Pharm Gmbh | Preformulation for the tableting of natural mixtures of conjugated estrogens |
| US8349819B2 (en) | 2002-10-09 | 2013-01-08 | Dr. Reddy's Laboratories New York, Inc. | Steroid extraction process from urine sources |
| US6992075B2 (en) * | 2003-04-04 | 2006-01-31 | Barr Laboratories, Inc. | C(14) estrogenic compounds |
| US8497258B2 (en) | 2005-11-12 | 2013-07-30 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
| US20090232897A1 (en) * | 2008-03-14 | 2009-09-17 | Bijayananda Sahoo | Pharmaceutical compositions comprising conjugated estrogens |
| US20110097401A1 (en) | 2009-06-12 | 2011-04-28 | Meritage Pharma, Inc. | Methods for treating gastrointestinal disorders |
| CA2768452A1 (en) * | 2009-07-16 | 2011-01-20 | Avantor Performance Materials, Inc. | Material and process for incorporation of low dosage active pharmaceutical ingredients and use thereof |
| BR112014012444B1 (pt) | 2011-11-23 | 2021-12-14 | Therapeuticsmd, Inc | Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US9717707B2 (en) * | 2011-12-08 | 2017-08-01 | Hexal Ag | Pharmaceutical statin composition |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
| US20210246928A1 (en) * | 2020-02-11 | 2021-08-12 | Carl Chasse | Fastener having improved wobble control, fastening system including the same, and method of forming the same |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3487152A (en) * | 1967-02-07 | 1969-12-30 | Hoffmann La Roche | Tablets containing 7 - chloro - 2 - methylamino - 5 - phenyl - 3h - 1,4 - benzodiazepine-4-oxide and conjugated estrogenic substances |
| US4154820A (en) * | 1976-02-23 | 1979-05-15 | Akzona Incorporated | Compositions containing alkali metal sulfate salts of conjugated estrogens and antioxidants as stabilizers |
| DE3535536A1 (de) * | 1985-10-04 | 1987-04-09 | Lentia Gmbh | Verfahren zum gleichzeitigen trocknen und granulieren von extraktstoffen aus enteiweisstem kaelberblut |
| EP0322020A1 (en) * | 1987-12-22 | 1989-06-28 | Akzo N.V. | Pharmaceutical dosage unit for treating climacteric complaints and osteoporosis |
| WO1997004752A1 (en) * | 1995-07-26 | 1997-02-13 | Duramed Pharmaceuticals, Inc. | Pharmaceutical compositions of conjugated estrogens and methods for their use |
| HU228765B1 (hu) | 1996-08-30 | 2013-05-28 | Abbott Products Gmbh | Eljárás ösztrogének kinyerésére kancavizeletbõl |
| DE59610985D1 (de) * | 1996-08-30 | 2004-05-19 | Solvay Pharm Gmbh | Verfahren zur gewinnung von oestrogenen aus stutenharn |
| US6200289B1 (en) | 1998-04-10 | 2001-03-13 | Milestone Scientific, Inc. | Pressure/force computer controlled drug delivery system and the like |
| JP2000156938A (ja) | 1998-11-19 | 2000-06-06 | Hokuto Denko Kk | 電池の充放電試験装置 |
| TWI332400B (en) * | 2001-12-14 | 2010-11-01 | Solvay Pharm Gmbh | Preformulation for the tableting of natural mixtures of conjugated estrogens |
-
2002
- 2002-11-29 TW TW091134752A patent/TWI332400B/zh not_active IP Right Cessation
- 2002-12-04 AR ARP020104698A patent/AR037642A1/es unknown
- 2002-12-12 EP EP02792980A patent/EP1458363B1/de not_active Expired - Lifetime
- 2002-12-12 ES ES02792980T patent/ES2403218T3/es not_active Expired - Lifetime
- 2002-12-12 WO PCT/EP2002/014104 patent/WO2003051337A1/de not_active Ceased
- 2002-12-12 CA CA002470209A patent/CA2470209A1/en not_active Abandoned
- 2002-12-12 MX MXPA04005767A patent/MXPA04005767A/es active IP Right Grant
- 2002-12-12 CN CNB028262077A patent/CN1298313C/zh not_active Expired - Fee Related
- 2002-12-12 BR BR0214954-0A patent/BR0214954A/pt not_active IP Right Cessation
- 2002-12-12 CN CNB2006101684418A patent/CN100502839C/zh not_active Expired - Fee Related
- 2002-12-12 PL PL368730A patent/PL205544B1/pl unknown
- 2002-12-12 AU AU2002358682A patent/AU2002358682B2/en not_active Ceased
- 2002-12-12 JP JP2003552270A patent/JP4695838B2/ja not_active Expired - Fee Related
-
2004
- 2004-06-14 US US10/866,095 patent/US8273728B2/en not_active Expired - Fee Related
-
2012
- 2012-05-30 US US13/483,530 patent/US8329679B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003051337A1 (de) | 2003-06-26 |
| JP2005516923A (ja) | 2005-06-09 |
| AU2002358682A1 (en) | 2003-06-30 |
| HK1104220A1 (zh) | 2008-01-11 |
| ES2403218T3 (es) | 2013-05-16 |
| CN1607944A (zh) | 2005-04-20 |
| CN1977862A (zh) | 2007-06-13 |
| HK1075007A1 (en) | 2005-12-02 |
| TW200408400A (en) | 2004-06-01 |
| PL368730A1 (en) | 2005-04-04 |
| CN100502839C (zh) | 2009-06-24 |
| MXPA04005767A (es) | 2004-09-10 |
| US8329679B2 (en) | 2012-12-11 |
| AU2002358682B2 (en) | 2009-03-26 |
| US20120237666A1 (en) | 2012-09-20 |
| JP4695838B2 (ja) | 2011-06-08 |
| TWI332400B (en) | 2010-11-01 |
| EP1458363B1 (de) | 2013-01-16 |
| CN1298313C (zh) | 2007-02-07 |
| BR0214954A (pt) | 2004-12-14 |
| PL205544B1 (pl) | 2010-04-30 |
| CA2470209A1 (en) | 2003-06-26 |
| US20050009800A1 (en) | 2005-01-13 |
| US8273728B2 (en) | 2012-09-25 |
| EP1458363A1 (de) | 2004-09-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |