AR036211A1 - Proceso para la preparacion de 5-formilftalida - Google Patents
Proceso para la preparacion de 5-formilftalidaInfo
- Publication number
- AR036211A1 AR036211A1 ARP020102954A ARP020102954A AR036211A1 AR 036211 A1 AR036211 A1 AR 036211A1 AR P020102954 A ARP020102954 A AR P020102954A AR P020102954 A ARP020102954 A AR P020102954A AR 036211 A1 AR036211 A1 AR 036211A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- formilftalida
- formylphthalide
- formula
- citalopram
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Proceso para la preparación de 5-formilftalida de fórmula (1) que comprende someter a hidrogenación un halogenuro de fórmula (2) donde Hal representa cloro, bromo o yodo, disuelto en un solvente dipolar aprótico. La 5-formilftalida así obtenida se usa como intermediario en la preparación del citalopram que se utiliza en la preparación de composiciones farmacéuticas indicadas en el tratamiento de la depresión.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01830518A EP1281708B1 (en) | 2001-08-02 | 2001-08-02 | Process for the preparation of 5-Formylphthalide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR036211A1 true AR036211A1 (es) | 2004-08-18 |
Family
ID=8184644
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP020102954A AR036211A1 (es) | 2001-08-02 | 2002-08-02 | Proceso para la preparacion de 5-formilftalida |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6888010B2 (es) |
| EP (1) | EP1281708B1 (es) |
| JP (1) | JP2005501057A (es) |
| KR (1) | KR20040047784A (es) |
| CN (1) | CN1262549C (es) |
| AR (1) | AR036211A1 (es) |
| AT (1) | ATE267821T1 (es) |
| AU (1) | AU2002325386B2 (es) |
| BG (1) | BG108555A (es) |
| BR (1) | BR0211857A (es) |
| CA (1) | CA2456005A1 (es) |
| DE (1) | DE60103530T2 (es) |
| DK (1) | DK1281708T3 (es) |
| ES (1) | ES2223766T3 (es) |
| HK (1) | HK1071358A1 (es) |
| HU (1) | HUP0401165A3 (es) |
| MX (1) | MXPA04001029A (es) |
| PL (1) | PL368076A1 (es) |
| PT (1) | PT1281708E (es) |
| TR (1) | TR200402044T4 (es) |
| TW (1) | TWI252848B (es) |
| WO (1) | WO2003011847A1 (es) |
| ZA (1) | ZA200400842B (es) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1319686B1 (it) * | 2000-12-12 | 2003-10-23 | C D Farmasint S R L | Procedimento di preparazione di citalopram. |
-
2001
- 2001-08-02 DE DE60103530T patent/DE60103530T2/de not_active Expired - Fee Related
- 2001-08-02 EP EP01830518A patent/EP1281708B1/en not_active Expired - Lifetime
- 2001-08-02 TR TR2004/02044T patent/TR200402044T4/xx unknown
- 2001-08-02 ES ES01830518T patent/ES2223766T3/es not_active Expired - Lifetime
- 2001-08-02 PT PT01830518T patent/PT1281708E/pt unknown
- 2001-08-02 DK DK01830518T patent/DK1281708T3/da active
- 2001-08-02 AT AT01830518T patent/ATE267821T1/de not_active IP Right Cessation
-
2002
- 2002-07-29 CN CNB028183258A patent/CN1262549C/zh not_active Expired - Fee Related
- 2002-07-29 BR BR0211857-2A patent/BR0211857A/pt not_active IP Right Cessation
- 2002-07-29 MX MXPA04001029A patent/MXPA04001029A/es not_active Application Discontinuation
- 2002-07-29 WO PCT/EP2002/008551 patent/WO2003011847A1/en active Application Filing
- 2002-07-29 CA CA002456005A patent/CA2456005A1/en not_active Abandoned
- 2002-07-29 KR KR10-2004-7001623A patent/KR20040047784A/ko active IP Right Grant
- 2002-07-29 HU HU0401165A patent/HUP0401165A3/hu unknown
- 2002-07-29 PL PL02368076A patent/PL368076A1/xx not_active Application Discontinuation
- 2002-07-29 AU AU2002325386A patent/AU2002325386B2/en not_active Ceased
- 2002-07-29 JP JP2003517039A patent/JP2005501057A/ja active Pending
- 2002-07-31 TW TW091117177A patent/TWI252848B/zh not_active IP Right Cessation
- 2002-08-02 AR ARP020102954A patent/AR036211A1/es unknown
-
2004
- 2004-01-30 BG BG108555A patent/BG108555A/bg unknown
- 2004-01-31 US US10/776,626 patent/US6888010B2/en not_active Expired - Fee Related
- 2004-02-02 ZA ZA200400842A patent/ZA200400842B/en unknown
-
2005
- 2005-05-13 HK HK05104032A patent/HK1071358A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200400842B (en) | 2005-02-02 |
| DK1281708T3 (da) | 2004-09-27 |
| TR200402044T4 (tr) | 2004-10-21 |
| WO2003011847A1 (en) | 2003-02-13 |
| HUP0401165A3 (en) | 2005-11-28 |
| ATE267821T1 (de) | 2004-06-15 |
| KR20040047784A (ko) | 2004-06-05 |
| CN1262549C (zh) | 2006-07-05 |
| ES2223766T3 (es) | 2005-03-01 |
| DE60103530D1 (de) | 2004-07-01 |
| DE60103530T2 (de) | 2005-06-30 |
| CA2456005A1 (en) | 2003-02-13 |
| TWI252848B (en) | 2006-04-11 |
| CN1555371A (zh) | 2004-12-15 |
| PT1281708E (pt) | 2004-10-29 |
| MXPA04001029A (es) | 2004-12-03 |
| AU2002325386B2 (en) | 2007-06-07 |
| PL368076A1 (en) | 2005-03-21 |
| BG108555A (bg) | 2005-03-31 |
| BR0211857A (pt) | 2004-09-21 |
| US20040225136A1 (en) | 2004-11-11 |
| US6888010B2 (en) | 2005-05-03 |
| EP1281708A1 (en) | 2003-02-05 |
| AU2002325386B8 (en) | 2003-02-17 |
| HK1071358A1 (en) | 2005-07-15 |
| EP1281708B1 (en) | 2004-05-26 |
| HUP0401165A2 (hu) | 2004-11-29 |
| JP2005501057A (ja) | 2005-01-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |