AR036194A1 - Uso de compuestos para la fabricacion de un medicamento que promueven la regeneracion de las neuronas o de las excrecencias neuriticas para el tratamiento de xeroftalmia y para la diminucion de la sensibilidad de la cornea despues de lasik u otras cirugias cuando los nervios corneales estan lesionad - Google Patents
Uso de compuestos para la fabricacion de un medicamento que promueven la regeneracion de las neuronas o de las excrecencias neuriticas para el tratamiento de xeroftalmia y para la diminucion de la sensibilidad de la cornea despues de lasik u otras cirugias cuando los nervios corneales estan lesionadInfo
- Publication number
- AR036194A1 AR036194A1 ARP020102872A ARP020102872A AR036194A1 AR 036194 A1 AR036194 A1 AR 036194A1 AR P020102872 A ARP020102872 A AR P020102872A AR P020102872 A ARP020102872 A AR P020102872A AR 036194 A1 AR036194 A1 AR 036194A1
- Authority
- AR
- Argentina
- Prior art keywords
- lasik
- regeneration
- promotes
- manufacture
- treatment
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7012—Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Uso de una cantidad terapéuticamente eficaz de una composición que comprende por lo menos un compuesto para la fabricación de un medicamento que promueve la regeneración de las neuronas o las excrecencias neuríticas para el tratamiento de xeroftalmía en las lesiones de los nervios corneales. Dichos trastornos son resultantes de lesiones en el nervio corneal después de LASIK y otras cirugías o traumas oculares. Los compuestos utilizados se pueden seleccionar del grupo que consiste en propentofilina, AIT-082 (neotrofina), idebenona, ONO-2506, CB-1093, NS521 (1-(1-butil)-4-(2-oxo-1-benzimidazona), piperidina, eliprodil, SR57746A (clorhidrato de xaliproden) o análogos de los mismos farmacéuticamente aceptables.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31565201P | 2001-08-29 | 2001-08-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR036194A1 true AR036194A1 (es) | 2004-08-18 |
Family
ID=23225436
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP020102872A AR036194A1 (es) | 2001-08-29 | 2002-07-30 | Uso de compuestos para la fabricacion de un medicamento que promueven la regeneracion de las neuronas o de las excrecencias neuriticas para el tratamiento de xeroftalmia y para la diminucion de la sensibilidad de la cornea despues de lasik u otras cirugias cuando los nervios corneales estan lesionad |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1420791A4 (es) |
JP (1) | JP2005502678A (es) |
CN (1) | CN1549718A (es) |
AR (1) | AR036194A1 (es) |
BR (1) | BR0212151A (es) |
CA (1) | CA2455896A1 (es) |
MX (1) | MXPA04001255A (es) |
PL (1) | PL368565A1 (es) |
WO (1) | WO2003020281A1 (es) |
ZA (1) | ZA200400837B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004091662A1 (ja) * | 2003-04-18 | 2004-10-28 | Senju Pharmaceutical Co. Ltd. | 角膜知覚回復剤 |
ES2234428B1 (es) * | 2003-12-09 | 2006-11-01 | Universidad Miguel Hernandez | Compuestos para el tratamiento de la sequedad de la superficie ocular provocada por la cirugia fotorrefractiva. |
CN1997381B (zh) * | 2004-04-23 | 2011-06-08 | 千寿制药株式会社 | 含有pacap及其衍生物的角膜神经突形成促进剂 |
JP4932480B2 (ja) * | 2004-06-03 | 2012-05-16 | 千寿製薬株式会社 | アミド化合物を含有する角膜知覚回復剤 |
US20090082455A1 (en) | 2005-03-15 | 2009-03-26 | Ono Pharmaceutical Co. Lted | Therapeutic agent for ophthalmic disease |
CN113350326B (zh) * | 2021-07-28 | 2023-03-17 | 爱尔眼科医院集团股份有限公司 | 化合物lm22b-10在制备角膜上皮及神经损伤治疗药物中的应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5166317A (en) * | 1988-10-31 | 1992-11-24 | Houston Biotechnology Incorporated | Neurotrophic factor |
FR2672213B1 (fr) * | 1991-02-05 | 1995-03-10 | Sanofi Sa | Utilisation de derives 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridiniques comme capteurs de radicaux libres. |
US5767079A (en) * | 1992-07-08 | 1998-06-16 | Celtrix Pharmaceuticals, Inc. | Method of treating ophthalmic disorders using TGF -β |
US5604244A (en) * | 1995-06-07 | 1997-02-18 | Alcon Laboratories, Inc. | Intraocular irrigating solution containing a polyamine antagonist |
TWI246421B (en) * | 1998-12-03 | 2006-01-01 | Alcon Mfg Ltd | Use of neurotrophic factor stimulators for the treatment of ophthalmic neurodegenerative diseases |
WO2001085152A2 (en) * | 2000-05-10 | 2001-11-15 | Alcon, Inc. | R-eliprodil for treating glaucoma |
-
2002
- 2002-07-23 BR BR0212151-4A patent/BR0212151A/pt not_active Application Discontinuation
- 2002-07-23 MX MXPA04001255A patent/MXPA04001255A/es not_active Application Discontinuation
- 2002-07-23 CA CA002455896A patent/CA2455896A1/en not_active Abandoned
- 2002-07-23 EP EP02756710A patent/EP1420791A4/en not_active Withdrawn
- 2002-07-23 JP JP2003524588A patent/JP2005502678A/ja not_active Withdrawn
- 2002-07-23 CN CNA028168682A patent/CN1549718A/zh active Pending
- 2002-07-23 WO PCT/US2002/023871 patent/WO2003020281A1/en not_active Application Discontinuation
- 2002-07-23 PL PL02368565A patent/PL368565A1/xx unknown
- 2002-07-30 AR ARP020102872A patent/AR036194A1/es unknown
-
2004
- 2004-02-02 ZA ZA200400837A patent/ZA200400837B/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP1420791A4 (en) | 2004-09-15 |
EP1420791A1 (en) | 2004-05-26 |
MXPA04001255A (es) | 2004-05-27 |
ZA200400837B (en) | 2005-02-02 |
JP2005502678A (ja) | 2005-01-27 |
CN1549718A (zh) | 2004-11-24 |
BR0212151A (pt) | 2004-08-24 |
WO2003020281A1 (en) | 2003-03-13 |
CA2455896A1 (en) | 2003-03-13 |
PL368565A1 (en) | 2005-04-04 |
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