AR029572A1 - Tiofen retinoides - Google Patents
Tiofen retinoidesInfo
- Publication number
- AR029572A1 AR029572A1 ARP010103228A ARP010103228A AR029572A1 AR 029572 A1 AR029572 A1 AR 029572A1 AR P010103228 A ARP010103228 A AR P010103228A AR P010103228 A ARP010103228 A AR P010103228A AR 029572 A1 AR029572 A1 AR 029572A1
- Authority
- AR
- Argentina
- Prior art keywords
- retinoid
- hydrogen
- retinoic acid
- alkyl
- formula
- Prior art date
Links
- 150000004492 retinoid derivatives Chemical class 0.000 title abstract 3
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 239000000018 receptor agonist Substances 0.000 abstract 2
- 229940044601 receptor agonist Drugs 0.000 abstract 2
- 102000003702 retinoic acid receptors Human genes 0.000 abstract 2
- 108090000064 retinoic acid receptors Proteins 0.000 abstract 2
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 206010014561 Emphysema Diseases 0.000 abstract 1
- 208000019693 Lung disease Diseases 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 229930002330 retinoic acid Natural products 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Chemical group 0.000 abstract 1
- 229960001727 tretinoin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00114767 | 2000-07-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR029572A1 true AR029572A1 (es) | 2003-07-02 |
Family
ID=8169205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010103228A AR029572A1 (es) | 2000-07-10 | 2001-07-06 | Tiofen retinoides |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6403810B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP1301505A2 (cg-RX-API-DMAC10.html) |
| JP (1) | JP2004502767A (cg-RX-API-DMAC10.html) |
| KR (1) | KR100551778B1 (cg-RX-API-DMAC10.html) |
| CN (1) | CN1219777C (cg-RX-API-DMAC10.html) |
| AR (1) | AR029572A1 (cg-RX-API-DMAC10.html) |
| AU (2) | AU2001289619B2 (cg-RX-API-DMAC10.html) |
| BR (1) | BR0112328A (cg-RX-API-DMAC10.html) |
| CA (1) | CA2414936C (cg-RX-API-DMAC10.html) |
| MX (1) | MXPA03000222A (cg-RX-API-DMAC10.html) |
| WO (1) | WO2002004439A2 (cg-RX-API-DMAC10.html) |
| ZA (1) | ZA200210049B (cg-RX-API-DMAC10.html) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200510298A (en) * | 2003-06-13 | 2005-03-16 | Theravance Inc | Substituted pyrrolidine and related compounds |
| US7476673B2 (en) * | 2003-12-30 | 2009-01-13 | Allergan, Inc. | Disubstituted chalcone oximes as selective agonists of RARγ retinoid receptors |
| EP1723142A1 (en) * | 2004-03-11 | 2006-11-22 | Theravance, Inc. | Diphenylmethyl compounds useful as muscarinic receptor antagonists |
| US20060161076A1 (en) * | 2005-01-06 | 2006-07-20 | Diamics, Inc. | Systems and methods for collection of cell clusters |
| US20060189893A1 (en) * | 2005-01-06 | 2006-08-24 | Diamics, Inc. | Systems and methods for detecting abnormal cells |
| US7781187B2 (en) * | 2005-12-30 | 2010-08-24 | Corning Incorporated | Fluorescent dyes |
| WO2008057930A2 (en) * | 2006-11-02 | 2008-05-15 | Aestus Therapeutics, Inc. | Methods of treating neuropathic pain with retinoic acid receptor agonists |
| CN122319252A (zh) | 2023-11-24 | 2026-06-30 | 伊泽阿恩埃免疫疗法股份有限公司 | 用于在IVT过程中减少dsRNA形成的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4123469A (en) | 1977-06-30 | 1978-10-31 | International Flavors & Fragrances Inc. | Process for production of bicyclic compounds |
| US5324840A (en) * | 1992-06-11 | 1994-06-28 | Allergan, Inc. | Method of treatment with compounds having retinoid-like activity and reduced skin toxicity and lacking teratogenic effects |
| US5455265A (en) * | 1993-02-11 | 1995-10-03 | Allergan, Inc. | Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors |
| US5399586A (en) * | 1993-03-11 | 1995-03-21 | Allergan, Inc. | Treatment of mammals afflicted with tumors with compounds having RXR retinoid receptor agonist activity |
| US5475022A (en) * | 1993-10-18 | 1995-12-12 | Allergan, Inc. | Phenyl or heteroaryl and tetrahydronaphthyl substituted diene compounds having retinoid like biological activity |
| FR2743560B1 (fr) * | 1996-01-17 | 1998-04-03 | Europ De Bioprospective Centre | Derives polycycliques aromatiques de type retinoide, leur procede de preparation et leur utilisation pour la fabrication de compositions pharmaceutiques et cosmetiques |
| FR2753091B1 (fr) | 1996-09-09 | 2001-03-16 | Oreal | Utilisation d'un agoniste des recepteurs des retinoides de type rxr pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute |
-
2001
- 2001-06-15 US US09/882,110 patent/US6403810B2/en not_active Expired - Fee Related
- 2001-06-30 CA CA002414936A patent/CA2414936C/en not_active Expired - Fee Related
- 2001-06-30 CN CNB01812660XA patent/CN1219777C/zh not_active Expired - Fee Related
- 2001-06-30 AU AU2001289619A patent/AU2001289619B2/en not_active Ceased
- 2001-06-30 MX MXPA03000222A patent/MXPA03000222A/es active IP Right Grant
- 2001-06-30 EP EP01969328A patent/EP1301505A2/en not_active Withdrawn
- 2001-06-30 AU AU8961901A patent/AU8961901A/xx active Pending
- 2001-06-30 KR KR1020037000289A patent/KR100551778B1/ko not_active Expired - Fee Related
- 2001-06-30 JP JP2002509304A patent/JP2004502767A/ja active Pending
- 2001-06-30 BR BR0112328-9A patent/BR0112328A/pt not_active IP Right Cessation
- 2001-06-30 WO PCT/EP2001/007506 patent/WO2002004439A2/en not_active Ceased
- 2001-07-06 AR ARP010103228A patent/AR029572A1/es unknown
-
2002
- 2002-12-11 ZA ZA200210049A patent/ZA200210049B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1219777C (zh) | 2005-09-21 |
| WO2002004439A2 (en) | 2002-01-17 |
| ZA200210049B (en) | 2004-03-11 |
| CA2414936C (en) | 2006-12-05 |
| KR100551778B1 (ko) | 2006-02-13 |
| AU2001289619B2 (en) | 2006-07-13 |
| US20020019438A1 (en) | 2002-02-14 |
| US6403810B2 (en) | 2002-06-11 |
| AU8961901A (en) | 2002-01-21 |
| CN1441798A (zh) | 2003-09-10 |
| KR20030040350A (ko) | 2003-05-22 |
| BR0112328A (pt) | 2003-07-22 |
| MXPA03000222A (es) | 2003-06-06 |
| EP1301505A2 (en) | 2003-04-16 |
| WO2002004439A3 (en) | 2002-09-26 |
| CA2414936A1 (en) | 2002-01-17 |
| JP2004502767A (ja) | 2004-01-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |