ES2045219T3 - Procedimiento para la preparacion de derivados del acido fenoxicarboxilico. - Google Patents

Procedimiento para la preparacion de derivados del acido fenoxicarboxilico.

Info

Publication number
ES2045219T3
ES2045219T3 ES89103897T ES89103897T ES2045219T3 ES 2045219 T3 ES2045219 T3 ES 2045219T3 ES 89103897 T ES89103897 T ES 89103897T ES 89103897 T ES89103897 T ES 89103897T ES 2045219 T3 ES2045219 T3 ES 2045219T3
Authority
ES
Spain
Prior art keywords
atom
derivatives
acid
phenoxicarboxilico
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89103897T
Other languages
English (en)
Inventor
Mitsuo Ohashi
Katsuya Awano
Toshio Tanaka
Tetsuya Kimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2045219T3 publication Critical patent/ES2045219T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/24—Sulfones; Sulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

DERIVADOS DEL ACIDO FENOXIALQUILCARBOXILICO DE LA FORMULA(I), DONDE R1 INDICA UN ATOMO DE H, GRUPO METILO O GRUPO ETILO, N ES UN NUMERO ENTERO ENTRE 2 Y 5, Y N ES UN ENTERO ENTRE 3 Y 8, X1 Y X2 ES INDEPENDIENTEMENTE UN ATOMO DE S, ATOMO DE H, GRUPO SULFINILO O GRUPO SULFONILO, SE PREVEE QUE X1 Y X2 NO SON A LA VEZ UN ATOMO DE O; SUS SALES ALCALINAS E HIDRATOS DE ESTAS SON UTILES COMO AGENTES ANTIALERGICOS.
ES89103897T 1988-03-07 1989-03-06 Procedimiento para la preparacion de derivados del acido fenoxicarboxilico. Expired - Lifetime ES2045219T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5337488 1988-03-07

Publications (1)

Publication Number Publication Date
ES2045219T3 true ES2045219T3 (es) 1994-01-16

Family

ID=12941043

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89103897T Expired - Lifetime ES2045219T3 (es) 1988-03-07 1989-03-06 Procedimiento para la preparacion de derivados del acido fenoxicarboxilico.

Country Status (9)

Country Link
US (2) US4985585A (es)
EP (1) EP0332109B1 (es)
KR (1) KR960007602B1 (es)
CN (1) CN1022407C (es)
AU (1) AU617439B2 (es)
CA (1) CA1331763C (es)
DE (1) DE68900485D1 (es)
ES (1) ES2045219T3 (es)
HU (2) HU208524B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4985585A (en) 1988-03-07 1991-01-15 Kyorin Pharmaceutical Co., Ltd. Phenoxyalkylcarboxylic acid derivatives and process for their preparations
US5290812A (en) * 1991-01-18 1994-03-01 Kyorin Pharmaceutical Co., Ltd. Phenoxyalkylcarboxylic acid derivatives and process of preparing the same
CA2397755A1 (en) 2000-01-26 2001-08-02 Kyorin Pharmaceutical Co., Ltd. Eye drops containing 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy)-2-propylphenoxy)butyic acid for the use in the treatment of allergic eye disease
US7060854B2 (en) * 2003-06-24 2006-06-13 Medicinova, Inc. Process for making polymorphic form A of 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid
US7064146B2 (en) * 2003-06-24 2006-06-20 Medicinova, Inc. Pharmaceutical compositions of isolated orthorhombic crystalline 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid and methods of use
WO2005105073A1 (en) * 2004-04-27 2005-11-10 Medicinova, Inc. Phenoxyalkycarboxylic acid derivatives in the treatment of inflammatory diseases
JP3983272B2 (ja) 2004-07-14 2007-09-26 有限会社 炎症研究所 腫瘍転移の抑制方法
JP2013119550A (ja) 2011-12-08 2013-06-17 Medicinova Inc 非アルコール性脂肪性肝疾患及び非アルコール性脂肪性肝炎の処置方法
US8962687B2 (en) 2012-12-05 2015-02-24 Medicinova, Inc. Method of treating liver disorders
WO2015013395A1 (en) 2013-07-25 2015-01-29 Medicinova, Inc. Methods for reducing triglyceride, total cholesterol and low density lipoprotein blood levels
US9346754B2 (en) 2014-05-08 2016-05-24 Medicinova, Inc. Method of treating advanced non-alcoholic steatohepatitis
US20150321989A1 (en) * 2014-05-08 2015-11-12 Medicinova, Inc. Method of treating idiopathic pulmonary fibrosis
WO2015187548A1 (en) 2014-06-02 2015-12-10 Medicinova, Inc. Method of inhibiting or treating fibrosis
WO2022251464A1 (en) 2021-05-28 2022-12-01 Medicinova, Inc. Phenoxyalkylcarboxylic acid derivatives and their use in lowering triglyceride levels

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2058785B (en) * 1979-09-05 1983-05-25 Glaxo Group Ltd Phenol derivatives
DE3169761D1 (en) * 1981-01-09 1985-05-09 Fisons Plc Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them
US4507498A (en) * 1982-04-09 1985-03-26 Hoffmann-La Roche Inc. Phenoxycarboxylic acids
IL69691A (en) * 1982-09-23 1988-01-31 Merck Frosst Canada Inc Leukotriene antagonists,their preparation and pharmaceutical compositions containing them
AU7450087A (en) * 1987-05-22 1988-11-24 Lunam, M.A. Pillow
JPH0819041B2 (ja) 1987-09-10 1996-02-28 杏林製薬株式会社 フェノキシアルキルカルボン酸誘導体及びその製造法
US4985585A (en) 1988-03-07 1991-01-15 Kyorin Pharmaceutical Co., Ltd. Phenoxyalkylcarboxylic acid derivatives and process for their preparations
US5290812A (en) 1991-01-18 1994-03-01 Kyorin Pharmaceutical Co., Ltd. Phenoxyalkylcarboxylic acid derivatives and process of preparing the same

Also Published As

Publication number Publication date
US4985585A (en) 1991-01-15
KR890014435A (ko) 1989-10-23
EP0332109B1 (en) 1991-12-04
HU912411D0 (en) 1991-12-30
HUT50112A (en) 1989-12-28
HU208524B (en) 1993-11-29
EP0332109A1 (en) 1989-09-13
CN1036560A (zh) 1989-10-25
AU617439B2 (en) 1991-11-28
DE68900485D1 (de) 1992-01-16
CA1331763C (en) 1994-08-30
CN1022407C (zh) 1993-10-13
KR960007602B1 (ko) 1996-06-07
HU204030B (en) 1991-11-28
USRE38921E1 (en) 2005-12-13
AU3088489A (en) 1989-09-07

Similar Documents

Publication Publication Date Title
ES2045219T3 (es) Procedimiento para la preparacion de derivados del acido fenoxicarboxilico.
ES2033049T3 (es) Procedimiento para preparar derivados de oxa- o tia-zolina.
MX162950B (es) Procedimiento para preparar derivados de acidos piridoncarboxilicos
ES2053778T3 (es) Procedimiento para la obtencion de derivados del tiazol.
ATE284853T1 (de) Ureido-thiobuttersäurederivate als ppar-agonisten
ES2031841T3 (es) Un procedimiento para la preparacion de derivados de 1,1-dioxido de 2-aminoalquil-1,2-benzoisotiazol-3-(2h)ona.
ES2031876T3 (es) Un procedimiento para la preparacion de 5,6-dihidro-2-(fenil sustituido)-1,2,4,-triazin-3,5(2h,4h)-dionas.
SE8404019D0 (sv) Oftalmiskt medel
AR247732A1 (es) Procedimiento para obtener amidas de acido piridin-2, 4- y -2, 5-dicarboxilico
ES2061546T3 (es) Compuestos quelantes de piridoxamina, quelatos de manganeso (ii) y su uso como agentes de contraste de nmri.
CO4340623A1 (es) Derivados de indolina, metodo de preparacion y uso
DE69225410D1 (de) Herstellung von n-acetylneuraminsäure-derivaten
FI812804L (fi) 2-(1,4-bensodioxan-2-ylalkyl)-imidazoler anvaendbara som antidepressiva laekemedel
NO873564D0 (no) Nye tyroninderivater.
ES2038260T3 (es) Procedimiento para la preparacion de derivados del acido fenoxialquilcarboxilico.
MX169371B (es) Agentes para lavar, estables en almacenamiento y procedimieto para su preparacion
ES455835A1 (es) Procedimientos para la preparacion de derivados de la pipe- ridina.
ES2053544T3 (es) Un procedimiento para la preparacion de nuevos derivados de indol tetraciclicos.
SE8303539D0 (sv) Polyenverbindungen
ES2066534T3 (es) Procedimiento para la oxidacion de derivados de hidroximetilpiridina en derivados de acido piridincarboxilico.
JPS5424861A (en) Novel 1,2,3,4-tetrahydro-naphthalene derivatives
ES2060854T3 (es) Procedimiento para la preparacion de acido 2-mercapto-4-metil-1,3-tiazol-5-il-acetico y sus esteres.
WO2001044205A3 (en) Phenanthryl piperazinyl dicarboxylic acids as selective nmda receptor modulating agents
JPS5283650A (en) Abietalinide derivatives
ES531252A0 (es) Procedimiento para la obtencion de iminosulfonamidas

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 332109

Country of ref document: ES