AR029453A1 - Procedimiento e intermedios para preparar acidos (4-cianosustituido)- ciclohexanoicos) - Google Patents

Procedimiento e intermedios para preparar acidos (4-cianosustituido)- ciclohexanoicos)

Info

Publication number
AR029453A1
AR029453A1 ARP000104805A ARP000104805A AR029453A1 AR 029453 A1 AR029453 A1 AR 029453A1 AR P000104805 A ARP000104805 A AR P000104805A AR P000104805 A ARP000104805 A AR P000104805A AR 029453 A1 AR029453 A1 AR 029453A1
Authority
AR
Argentina
Prior art keywords
cyclohexanoics
cyanosustituded
intermediates
procedure
formula
Prior art date
Application number
ARP000104805A
Other languages
English (en)
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of AR029453A1 publication Critical patent/AR029453A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/30Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/45Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/46Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Furan Compounds (AREA)

Abstract

Se proporciona aqui un procedimiento para preparar ácidos ciclohexanoicos sustituidos de la formula 1 donde Ra es un grupo que contiene carbono opcionalmente ligado por oxígeno, azufre o nitrogeno al anillo fenilo y j es 1-5 y uno de los R y R* es hidrogeno y el otro es C (O)OH, cuyo procedimiento comprende reducir catalíticamente una cetona de la formula 2 donde alquilo tiene C1-6 y (Ra)j es el mismo que se definio anteriormente, empleando un catalizador de metal pesado y gas hidrogeno.
ARP000104805A 1999-09-15 2000-09-13 Procedimiento e intermedios para preparar acidos (4-cianosustituido)- ciclohexanoicos) AR029453A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15408499P 1999-09-15 1999-09-15

Publications (1)

Publication Number Publication Date
AR029453A1 true AR029453A1 (es) 2003-07-02

Family

ID=22549941

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000104805A AR029453A1 (es) 1999-09-15 2000-09-13 Procedimiento e intermedios para preparar acidos (4-cianosustituido)- ciclohexanoicos)

Country Status (24)

Country Link
US (1) US6624323B1 (es)
EP (1) EP1220833A4 (es)
JP (1) JP2003509405A (es)
KR (1) KR20020033802A (es)
CN (3) CN1240673C (es)
AR (1) AR029453A1 (es)
AU (1) AU775587B2 (es)
BR (1) BR0014011A (es)
CA (1) CA2385153A1 (es)
CO (1) CO5241281A1 (es)
CZ (1) CZ2002916A3 (es)
HK (1) HK1049145A1 (es)
HU (1) HUP0202680A3 (es)
IL (1) IL148332A0 (es)
MY (1) MY126799A (es)
NO (1) NO20021034D0 (es)
NZ (1) NZ517449A (es)
PE (1) PE20010599A1 (es)
PL (1) PL354656A1 (es)
TR (1) TR200200657T2 (es)
TW (1) TWI231811B (es)
UY (1) UY26333A1 (es)
WO (1) WO2001019785A1 (es)
ZA (1) ZA200201985B (es)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK279958B6 (sk) * 1992-04-02 1999-06-11 Smithkline Beecham Corporation Zlúčeniny s protialergickým a protizápalovým účink
WO1995003794A1 (en) * 1993-07-30 1995-02-09 Smithkline Beecham Corporation 3-cyano-3-(3,4-disubstituted)phenylcyclohexyl-1-carboxylates
AU7957794A (en) * 1993-10-01 1995-05-01 Smithkline Beecham Corporation Anti-allergic, anti-inflammatory compounds, compositions and uses
GB9404706D0 (en) * 1994-03-11 1994-04-27 Smithkline Beecham Corp Compounds

Also Published As

Publication number Publication date
CN1266120C (zh) 2006-07-26
JP2003509405A (ja) 2003-03-11
BR0014011A (pt) 2002-11-19
AU7703000A (en) 2001-04-17
NO20021034L (no) 2002-03-01
US6624323B1 (en) 2003-09-23
NZ517449A (en) 2004-02-27
TWI231811B (en) 2005-05-01
EP1220833A1 (en) 2002-07-10
UY26333A1 (es) 2001-07-31
CN1240673C (zh) 2006-02-08
CN1532188A (zh) 2004-09-29
WO2001019785A1 (en) 2001-03-22
CN1374941A (zh) 2002-10-16
CO5241281A1 (es) 2003-01-31
CN1532187A (zh) 2004-09-29
CZ2002916A3 (cs) 2002-06-12
HK1049145A1 (zh) 2003-05-02
KR20020033802A (ko) 2002-05-07
PL354656A1 (en) 2004-02-09
IL148332A0 (en) 2002-09-12
EP1220833A4 (en) 2004-12-22
PE20010599A1 (es) 2001-07-07
HUP0202680A2 (hu) 2002-12-28
AU775587B2 (en) 2004-08-05
MY126799A (en) 2006-10-31
TR200200657T2 (tr) 2002-07-22
NO20021034D0 (no) 2002-03-01
CN1266121C (zh) 2006-07-26
ZA200201985B (en) 2002-12-24
CA2385153A1 (en) 2001-03-22
HUP0202680A3 (en) 2003-01-28

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