AR025655A1 - Tripsina libre de quimotripsina - Google Patents

Tripsina libre de quimotripsina

Info

Publication number
AR025655A1
AR025655A1 ARP000104808A ARP000104808A AR025655A1 AR 025655 A1 AR025655 A1 AR 025655A1 AR P000104808 A ARP000104808 A AR P000104808A AR P000104808 A ARP000104808 A AR P000104808A AR 025655 A1 AR025655 A1 AR 025655A1
Authority
AR
Argentina
Prior art keywords
free
chemotripsine
tripsine
chymotrypsin
essentially free
Prior art date
Application number
ARP000104808A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of AR025655A1 publication Critical patent/AR025655A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6427—Chymotrypsins (3.4.21.1; 3.4.21.2); Trypsin (3.4.21.4)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente se refiere a productos de tripsina y tripsinogeno esencialmente libres de quimotripsina, producidos recombinantemente. También incluyereactivos y procedimientos para producir tripsinogeno recombinante que puede activarsesubsiguientemente para formar tripsina esencialmente libre dequimotripsina.
ARP000104808A 1999-09-15 2000-09-13 Tripsina libre de quimotripsina AR025655A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15401999P 1999-09-15 1999-09-15

Publications (1)

Publication Number Publication Date
AR025655A1 true AR025655A1 (es) 2002-12-11

Family

ID=22549683

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000104808A AR025655A1 (es) 1999-09-15 2000-09-13 Tripsina libre de quimotripsina

Country Status (4)

Country Link
AR (1) AR025655A1 (es)
AU (1) AU7053500A (es)
PE (1) PE20010596A1 (es)
WO (1) WO2001019970A2 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1627920A1 (en) * 2000-01-24 2006-02-22 Polymun Scientific Immunbiologische Forschung GmbH Method for the manufacture of recombinant trypsin
CZ303658B6 (cs) 2001-02-01 2013-02-06 F. Hoffmann-La Roche Ag Zpusob rekombinantní produkce trypsinu
WO2012104099A1 (en) * 2011-02-04 2012-08-09 Glucometrix Ag Process for the production of recombinant trypsin
CN103966191B (zh) * 2013-02-04 2016-01-20 甘李药业股份有限公司 一种重组牛源性胰蛋白酶的制备方法
WO2014167574A1 (en) * 2013-03-22 2014-10-16 Biogenomics Limited Process for isolation and stabilisation of key intermediates for high efficiency refolding of recombinant proteins
WO2016081288A1 (en) * 2014-11-18 2016-05-26 Merck Sharp & Dohme Corp. Process for refolding recombinant chymotrypsin
WO2016081289A1 (en) 2014-11-18 2016-05-26 Merck Sharp & Dohme Corp. Process for producing recombinant trypsin
CN104694522B (zh) * 2015-02-16 2018-06-12 中国人民解放军军事医学科学院放射与辐射医学研究所 一种重组乙酰化阳离子型胰蛋白酶的制备方法及其应用
WO2021091932A1 (en) * 2019-11-07 2021-05-14 Amgen Inc. High salt load conditioning during cation exchange chromatography to remove product-realated impurities
GB202015618D0 (en) * 2020-10-01 2020-11-18 Ipsen Biopharm Ltd Method for producing beta-trypsin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3835350A1 (de) * 1988-10-17 1990-04-19 Boehringer Mannheim Gmbh Aktivierung von gentechnologisch hergestellten, in prokaryonten exprimierten antikoerpern
DE4140699A1 (de) * 1991-01-11 1992-07-16 Boehringer Mannheim Gmbh Rekombinante iga-protease
IL107536A0 (en) * 1992-11-13 1994-02-27 Lilly Co Eli Expression vectors for bovine trypsin and trypsinogen and host cells transformed therewith
DK1012307T3 (da) * 1997-08-22 2005-09-05 Roche Diagnostics Gmbh Autokatalytisk aktiverbare zymogene proteaseforstadier og deres anvendelse
EP1141263A4 (en) * 1998-09-21 2002-08-28 Lilly Co Eli PRODUCTION OF SOLUBLE RECOMBINANT TRYPSIN ANALOGS

Also Published As

Publication number Publication date
AU7053500A (en) 2001-04-17
PE20010596A1 (es) 2001-05-23
WO2001019970A3 (en) 2001-11-15
WO2001019970A2 (en) 2001-03-22

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