AR025655A1 - CHEMOTRIPSINE FREE TRIPSINE - Google Patents

CHEMOTRIPSINE FREE TRIPSINE

Info

Publication number
AR025655A1
AR025655A1 ARP000104808A ARP000104808A AR025655A1 AR 025655 A1 AR025655 A1 AR 025655A1 AR P000104808 A ARP000104808 A AR P000104808A AR P000104808 A ARP000104808 A AR P000104808A AR 025655 A1 AR025655 A1 AR 025655A1
Authority
AR
Argentina
Prior art keywords
free
chemotripsine
tripsine
chymotrypsin
essentially free
Prior art date
Application number
ARP000104808A
Other languages
Spanish (es)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of AR025655A1 publication Critical patent/AR025655A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6427—Chymotrypsins (3.4.21.1; 3.4.21.2); Trypsin (3.4.21.4)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente se refiere a productos de tripsina y tripsinogeno esencialmente libres de quimotripsina, producidos recombinantemente. También incluyereactivos y procedimientos para producir tripsinogeno recombinante que puede activarsesubsiguientemente para formar tripsina esencialmente libre dequimotripsina.This refers to trypsin and trypsinogen products essentially free of chymotrypsin, recombinantly produced. It also includes reagents and methods for producing recombinant trypsinogen that can subsequently be activated to form trypsin essentially free of chymotrypsin.

ARP000104808A 1999-09-15 2000-09-13 CHEMOTRIPSINE FREE TRIPSINE AR025655A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15401999P 1999-09-15 1999-09-15

Publications (1)

Publication Number Publication Date
AR025655A1 true AR025655A1 (en) 2002-12-11

Family

ID=22549683

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000104808A AR025655A1 (en) 1999-09-15 2000-09-13 CHEMOTRIPSINE FREE TRIPSINE

Country Status (4)

Country Link
AR (1) AR025655A1 (en)
AU (1) AU7053500A (en)
PE (1) PE20010596A1 (en)
WO (1) WO2001019970A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1627920A1 (en) * 2000-01-24 2006-02-22 Polymun Scientific Immunbiologische Forschung GmbH Method for the manufacture of recombinant trypsin
US7276605B2 (en) * 2001-02-01 2007-10-02 Roche Diagnostics Operations, Inc. Method for producing recombinant trypsin
WO2012104099A1 (en) * 2011-02-04 2012-08-09 Glucometrix Ag Process for the production of recombinant trypsin
CN103966191B (en) * 2013-02-04 2016-01-20 甘李药业股份有限公司 The tryptic preparation method of a kind of recombinant bovine source property
WO2014167574A1 (en) * 2013-03-22 2014-10-16 Biogenomics Limited Process for isolation and stabilisation of key intermediates for high efficiency refolding of recombinant proteins
US10301611B2 (en) 2014-11-18 2019-05-28 Merck Sharp & Dohme Corp. Process for refolding recombinant chymotrypsin
WO2016081289A1 (en) 2014-11-18 2016-05-26 Merck Sharp & Dohme Corp. Process for producing recombinant trypsin
CN104694522B (en) * 2015-02-16 2018-06-12 中国人民解放军军事医学科学院放射与辐射医学研究所 A kind of preparation method and applications for recombinating acetylation cationic trypsase
BR112022008649A2 (en) * 2019-11-07 2022-07-19 Amgen Inc HIGH SALT LOAD CONDITIONING DURING CATION EXCHANGE CHROMATOGRAPHY TO REMOVE PRODUCT-RELATED IMPURITIES
GB202015618D0 (en) * 2020-10-01 2020-11-18 Ipsen Biopharm Ltd Method for producing beta-trypsin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3835350A1 (en) * 1988-10-17 1990-04-19 Boehringer Mannheim Gmbh ACTIVATION OF GENETICALLY MANUFACTURED ANTIBODY EXPRESSED IN PROKARYONS
DE4140699A1 (en) * 1991-01-11 1992-07-16 Boehringer Mannheim Gmbh RECOMBINANT IGA PROTEASE
CA2102673A1 (en) * 1992-11-13 1994-05-14 Michael G. Greaney Expression vectors for bovine trypsin and trypsinogen and host cells transformed therewith
JP3947653B2 (en) * 1997-08-22 2007-07-25 ロシュ ダイアグノスティックス ゲーエムベーハー Proteolytically activatable zymogen precursors of proteases and their use
CA2343966A1 (en) * 1998-09-21 2000-03-30 Eli Lilly And Company Production of soluble recombinant trypsinogen analogs

Also Published As

Publication number Publication date
PE20010596A1 (en) 2001-05-23
AU7053500A (en) 2001-04-17
WO2001019970A2 (en) 2001-03-22
WO2001019970A3 (en) 2001-11-15

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