AR025461A1 - Un proceso para la preparacion de clorhidrato de cis-(1s-4s)-n-metil-4-(3,4-diclorofenil)-1,2,3,4-tetrahidro-1-naftalenamina - Google Patents
Un proceso para la preparacion de clorhidrato de cis-(1s-4s)-n-metil-4-(3,4-diclorofenil)-1,2,3,4-tetrahidro-1-naftalenaminaInfo
- Publication number
- AR025461A1 AR025461A1 ARP000104545A ARP000104545A AR025461A1 AR 025461 A1 AR025461 A1 AR 025461A1 AR P000104545 A ARP000104545 A AR P000104545A AR P000104545 A ARP000104545 A AR P000104545A AR 025461 A1 AR025461 A1 AR 025461A1
- Authority
- AR
- Argentina
- Prior art keywords
- cis
- tetrahydro
- methyl
- hydrochloride
- dichlorophenyl
- Prior art date
Links
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 title 1
- 241000243320 Hydrozoa Species 0.000 title 1
- BAVYZALUXZFZLV-UHFFFAOYSA-N Methylamine Chemical compound NC BAVYZALUXZFZLV-UHFFFAOYSA-N 0.000 abstract 2
- -1 amine hydrochloride Chemical class 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- JGMBHJNMQVKDMW-UHFFFAOYSA-N 4-(3,4-dichlorophenyl)-3,4-dihydro-2h-naphthalen-1-one Chemical compound C1=C(Cl)C(Cl)=CC=C1C1C2=CC=CC=C2C(=O)CC1 JGMBHJNMQVKDMW-UHFFFAOYSA-N 0.000 abstract 1
- GLQPTZAAUROJMO-UHFFFAOYSA-N 4-(3,4-dimethoxyphenyl)benzaldehyde Chemical compound C1=C(OC)C(OC)=CC=C1C1=CC=C(C=O)C=C1 GLQPTZAAUROJMO-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 239000007868 Raney catalyst Substances 0.000 abstract 1
- NPXOKRUENSOPAO-UHFFFAOYSA-N Raney nickel Chemical compound [Al].[Ni] NPXOKRUENSOPAO-UHFFFAOYSA-N 0.000 abstract 1
- 229910000564 Raney nickel Inorganic materials 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- 229960003660 sertraline hydrochloride Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/24—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
- C07C209/26—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds by reduction with hydrogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN748CA1999 IN185109B (enExample) | 1999-09-01 | 1999-09-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR025461A1 true AR025461A1 (es) | 2002-11-27 |
Family
ID=11084493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000104545A AR025461A1 (es) | 1999-09-01 | 2000-08-31 | Un proceso para la preparacion de clorhidrato de cis-(1s-4s)-n-metil-4-(3,4-diclorofenil)-1,2,3,4-tetrahidro-1-naftalenamina |
Country Status (4)
| Country | Link |
|---|---|
| AR (1) | AR025461A1 (enExample) |
| AU (1) | AU6587500A (enExample) |
| IN (1) | IN185109B (enExample) |
| WO (1) | WO2001016089A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001068566A1 (en) | 2000-03-14 | 2001-09-20 | Teva Pharmaceutical Industries Ltd. | Novel process for preparing (+)-cis-sertraline |
| CA2448300A1 (en) * | 2001-05-31 | 2002-12-05 | Orion Corporation Fermion | Process for preparing sertraline intermediates |
| US6723878B2 (en) | 2001-06-15 | 2004-04-20 | Orion Corporation Fermion | Method for preparing sertraline |
| WO2003093217A1 (en) | 2002-04-29 | 2003-11-13 | Teva Pharmaceutical Industries Ltd. | Process for preparation of polymorphic form ii of sertraline hydrochloride, pharmaceutical formulations and methods of administration thereof |
| WO2004092110A2 (en) | 2003-04-14 | 2004-10-28 | Teva Pharmaceutical Industries Ltd. | Hydrogenation of imine intermediates of sertraline with catalysts |
| CA2537804A1 (en) | 2003-09-05 | 2005-03-17 | Teva Pharmaceutical Industries Ltd | A recycling process for preparing sertraline |
| EP1851189A1 (en) * | 2005-02-23 | 2007-11-07 | Teva Pharmaceutical Industries Ltd | Processes for preparing sertraline |
| US7345201B2 (en) | 2005-02-23 | 2008-03-18 | Teva Pharmaceutical Industries, Ltd. | Processes for preparing sertraline |
| CA2576097C (en) | 2005-06-03 | 2009-10-27 | Hetero Drugs Limited | A highly stereoselective synthesis of sertraline |
| WO2007119247A2 (en) * | 2006-04-17 | 2007-10-25 | Unichem Laboratories Limited | Improved manufacturing procedure for the preparation of polymorphic form ii of cis-(1s)-n-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthleneamine hydrochloride (sertraline hydrochloride) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4536518A (en) * | 1979-11-01 | 1985-08-20 | Pfizer Inc. | Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
| IN191358B (enExample) * | 1998-01-16 | 2003-11-29 | Pfizer Prod Inc |
-
1999
- 1999-09-01 IN IN748CA1999 patent/IN185109B/en unknown
-
2000
- 2000-08-28 AU AU65875/00A patent/AU6587500A/en not_active Abandoned
- 2000-08-28 WO PCT/IB2000/001182 patent/WO2001016089A1/en not_active Ceased
- 2000-08-31 AR ARP000104545A patent/AR025461A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IN185109B (enExample) | 2000-11-18 |
| WO2001016089A1 (en) | 2001-03-08 |
| AU6587500A (en) | 2001-03-26 |
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