MXPA05011038A - Hidrogenacion de compuestos intermedios de imina de sertralina con catalizadores. - Google Patents
Hidrogenacion de compuestos intermedios de imina de sertralina con catalizadores.Info
- Publication number
- MXPA05011038A MXPA05011038A MXPA05011038A MXPA05011038A MXPA05011038A MX PA05011038 A MXPA05011038 A MX PA05011038A MX PA05011038 A MXPA05011038 A MX PA05011038A MX PA05011038 A MXPA05011038 A MX PA05011038A MX PA05011038 A MXPA05011038 A MX PA05011038A
- Authority
- MX
- Mexico
- Prior art keywords
- catalysts
- sertraline
- hydrogenation
- imine intermediates
- intermediates
- Prior art date
Links
- 239000003054 catalyst Substances 0.000 title abstract 2
- 238000005984 hydrogenation reaction Methods 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 title abstract 2
- 150000002466 imines Chemical class 0.000 title 1
- VGKDLMBJGBXTGI-SJCJKPOMSA-N sertraline Chemical compound C1([C@@H]2CC[C@@H](C3=CC=CC=C32)NC)=CC=C(Cl)C(Cl)=C1 VGKDLMBJGBXTGI-SJCJKPOMSA-N 0.000 title 1
- 229960002073 sertraline Drugs 0.000 title 1
- MGBVAZJASCWJGJ-LBPRGKRZSA-N (4s)-4-(3,4-dichlorophenyl)-n-methyl-3,4-dihydro-2h-naphthalen-1-imine Chemical compound C1([C@@H]2CCC(C3=CC=CC=C32)=NC)=CC=C(Cl)C(Cl)=C1 MGBVAZJASCWJGJ-LBPRGKRZSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
- C07C209/52—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
- B01J23/74—Iron group metals
- B01J23/75—Cobalt
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J35/00—Catalysts, in general, characterised by their form or physical properties
- B01J35/60—Catalysts, in general, characterised by their form or physical properties characterised by their surface properties or porosity
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J35/00—Catalysts, in general, characterised by their form or physical properties
- B01J35/60—Catalysts, in general, characterised by their form or physical properties characterised by their surface properties or porosity
- B01J35/61—Surface area
- B01J35/613—10-100 m2/g
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J35/00—Catalysts, in general, characterised by their form or physical properties
- B01J35/60—Catalysts, in general, characterised by their form or physical properties characterised by their surface properties or porosity
- B01J35/64—Pore diameter
- B01J35/647—2-50 nm
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials Engineering (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Se proporcionan proceso de hidrogenacion de compuestos intermedios de imina de sertralina con catalizadores en diferentes reactores.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46281603P | 2003-04-14 | 2003-04-14 | |
PCT/US2004/011634 WO2004092110A2 (en) | 2003-04-14 | 2004-04-14 | Hydrogenation of imine intermediates of sertraline with catalysts |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA05011038A true MXPA05011038A (es) | 2006-01-24 |
Family
ID=33299994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05011038A MXPA05011038A (es) | 2003-04-14 | 2004-04-14 | Hidrogenacion de compuestos intermedios de imina de sertralina con catalizadores. |
Country Status (8)
Country | Link |
---|---|
US (3) | US7276629B2 (es) |
EP (1) | EP1583734A2 (es) |
CA (1) | CA2522534A1 (es) |
DE (1) | DE04750154T1 (es) |
ES (1) | ES2242555T1 (es) |
MX (1) | MXPA05011038A (es) |
TW (1) | TW200503991A (es) |
WO (1) | WO2004092110A2 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200503991A (en) * | 2003-04-14 | 2005-02-01 | Teva Pharma | Hydrogenation of imine intermediates of sertraline with catalysts |
US7262327B2 (en) * | 2003-09-05 | 2007-08-28 | Teva Pharmaceutical Industries Ltd. | Recycling process for preparing sertraline |
WO2006072878A1 (en) * | 2005-01-07 | 2006-07-13 | Ranbaxy Laboratories Limited | Oral dosage forms of sertraline having controlled particle size and processes for their preparation |
TW200640836A (en) * | 2005-02-23 | 2006-12-01 | Teva Pharma | Processes for preparing sertraline |
WO2008071640A2 (en) * | 2006-12-12 | 2008-06-19 | Shell Internationale Research Maatschappij B.V. | Process for preparing a catalyst |
WO2010076763A2 (en) * | 2009-01-02 | 2010-07-08 | Piramal Healthcare Limited | An improved process for the manufacture of sertraline |
US8233987B2 (en) | 2009-09-10 | 2012-07-31 | Respicardia, Inc. | Respiratory rectification |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2486361A (en) * | 1944-10-20 | 1949-10-25 | Union Oil Co | Catalytic conversion of hydrocarbons |
US3274124A (en) * | 1964-01-02 | 1966-09-20 | Universal Oil Prod Co | Process of preparing a silica-alumina supported group viii metal hydrocracking catalyst |
JPS5439349B1 (es) * | 1971-06-08 | 1979-11-27 | ||
US3926842A (en) * | 1973-01-02 | 1975-12-16 | Texaco Inc | Method of regenerating spent hydroalkylation catalyst containing an oxidizable group viii metal |
FR2398540A1 (fr) * | 1977-07-29 | 1979-02-23 | Raffinage Cie Francaise | Procede de preparation d'alumines a porosite controlee et applications des alumines ainsi preparees |
US4536518A (en) | 1979-11-01 | 1985-08-20 | Pfizer Inc. | Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
GB9114948D0 (en) * | 1991-07-11 | 1991-08-28 | Pfizer Ltd | Process for preparing sertraline intermediates |
US5252613A (en) * | 1992-12-18 | 1993-10-12 | Exxon Research & Engineering Company | Enhanced catalyst mixing in slurry bubble columns (OP-3723) |
HU222341B1 (hu) | 1996-12-18 | 2003-06-28 | Richter Gedeon Vegyészeti Gyár Rt. | Eljárás sertralin előállítására és az eljárásban alkalmazott intermedier |
US5939350A (en) * | 1997-02-10 | 1999-08-17 | Energy International Corporation | Processes and catalysts for conducting fischer-tropsch synthesis in a slurry bubble column reactor |
WO1999047486A1 (en) * | 1998-03-18 | 1999-09-23 | Ciba Specialty Chemicals Holding Inc. | Process for the cis-selective catalytic hydrogenation of cyclohexylidenamines |
HU226424B1 (en) * | 1998-05-05 | 2008-12-29 | Egis Gyogyszergyar Nyrt | Process for producing enantiomer mixture for preparation of sertraline |
WO2000025598A1 (en) * | 1998-11-03 | 2000-05-11 | Dandy A/S | Sucrose fatty acid esters for use as increased release of active ingredients |
US6262132B1 (en) * | 1999-05-21 | 2001-07-17 | Energy International Corporation | Reducing fischer-tropsch catalyst attrition losses in high agitation reaction systems |
US6593496B1 (en) * | 1999-06-09 | 2003-07-15 | Pfizer Inc | Process for preparing sertraline from chiral tetralone |
WO2001009080A1 (en) * | 1999-07-29 | 2001-02-08 | Ciba Specialty Chemicals Holding Inc. | Process for the cis-selective catalytic hydrogenation of cyclohexylidenamines |
IN185109B (es) | 1999-09-01 | 2000-11-18 | Torrent Pharmaceuticals Ltd | |
IN187170B (es) * | 2000-01-04 | 2002-02-23 | Sun Pharmaceutical Ind Ltd | |
JP2003527359A (ja) * | 2000-03-14 | 2003-09-16 | テバ ファーマシューティカル インダストリーズ リミティド | (+)−シス−セルトラリンの製造のための新規方法 |
EP1401800A1 (en) * | 2001-06-15 | 2004-03-31 | Orion Corporation Fermion | A novel process for the preparation of (is-cis) -4-(3, 4-dichlorophenyl) -1, 2, 3, 4 - tetrahydro-n-methyl-1-naphthalenamine |
US6683220B2 (en) | 2001-10-31 | 2004-01-27 | Pfizer, Inc. | Process for the preparation of optically pure or enriched racemic tetralone |
TW200503991A (en) * | 2003-04-14 | 2005-02-01 | Teva Pharma | Hydrogenation of imine intermediates of sertraline with catalysts |
-
2004
- 2004-04-14 TW TW093110389A patent/TW200503991A/zh unknown
- 2004-04-14 CA CA002522534A patent/CA2522534A1/en not_active Abandoned
- 2004-04-14 DE DE04750154T patent/DE04750154T1/de active Pending
- 2004-04-14 WO PCT/US2004/011634 patent/WO2004092110A2/en active Application Filing
- 2004-04-14 EP EP04750154A patent/EP1583734A2/en not_active Withdrawn
- 2004-04-14 ES ES04750154T patent/ES2242555T1/es active Pending
- 2004-04-14 MX MXPA05011038A patent/MXPA05011038A/es unknown
- 2004-04-14 US US10/825,386 patent/US7276629B2/en not_active Expired - Fee Related
-
2006
- 2006-12-21 US US11/645,081 patent/US20080004351A1/en not_active Abandoned
-
2008
- 2008-05-02 US US12/151,068 patent/US20080207439A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ES2242555T1 (es) | 2005-11-16 |
DE04750154T1 (de) | 2005-12-29 |
US20080207439A1 (en) | 2008-08-28 |
TW200503991A (en) | 2005-02-01 |
EP1583734A2 (en) | 2005-10-12 |
US20080004351A1 (en) | 2008-01-03 |
WO2004092110A3 (en) | 2005-06-09 |
CA2522534A1 (en) | 2004-10-28 |
WO2004092110A2 (en) | 2004-10-28 |
WO2004092110B1 (en) | 2005-09-01 |
US7276629B2 (en) | 2007-10-02 |
US20050085669A1 (en) | 2005-04-21 |
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