AR020300A1 - Procedimiento para preparar sertralina a partir de tetralona quiral. - Google Patents

Procedimiento para preparar sertralina a partir de tetralona quiral.

Info

Publication number
AR020300A1
AR020300A1 ARP000102832A ARP000102832A AR020300A1 AR 020300 A1 AR020300 A1 AR 020300A1 AR P000102832 A ARP000102832 A AR P000102832A AR P000102832 A ARP000102832 A AR P000102832A AR 020300 A1 AR020300 A1 AR 020300A1
Authority
AR
Argentina
Prior art keywords
procedure
chiral tetralone
sertraline
prepare
prepare sertraline
Prior art date
Application number
ARP000102832A
Other languages
English (en)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR020300A1 publication Critical patent/AR020300A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Este invento se refiere a un procedimiento nuevo y mejorado para preparar el enantiomero (+) de la N-[4-(3,4-diclorofenil)-3,4-dihidro-1 (2H)-naftaleniliden]metanamina haciendo reaccionar el enantiomero (+) de la 4-(3,4-diclorofenil)-3,4-dihidro-1 (2H)-naftalenona con monometilamina y con cloruro detitanio o tamices moleculares.
ARP000102832A 1999-06-09 2000-06-07 Procedimiento para preparar sertralina a partir de tetralona quiral. AR020300A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13834099P 1999-06-09 1999-06-09

Publications (1)

Publication Number Publication Date
AR020300A1 true AR020300A1 (es) 2002-05-02

Family

ID=22481595

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000102832A AR020300A1 (es) 1999-06-09 2000-06-07 Procedimiento para preparar sertralina a partir de tetralona quiral.

Country Status (16)

Country Link
US (1) US6593496B1 (es)
EP (1) EP1059287A1 (es)
JP (1) JP3529703B2 (es)
KR (1) KR20010066820A (es)
CN (1) CN1277188A (es)
AR (1) AR020300A1 (es)
AU (1) AU767319B2 (es)
BR (1) BR0002606A (es)
CA (1) CA2310799C (es)
HU (1) HUP0002229A3 (es)
ID (1) ID26278A (es)
IL (1) IL136513A (es)
PL (1) PL340620A1 (es)
RU (1) RU2181358C2 (es)
TR (1) TR200001657A2 (es)
YU (1) YU32700A (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003527359A (ja) * 2000-03-14 2003-09-16 テバ ファーマシューティカル インダストリーズ リミティド （＋）−シス−セルトラリンの製造のための新規方法
US20030013768A1 (en) * 2001-05-31 2003-01-16 Orion Coproration Fermion Process for the production of sertraline and intermediates useful therefor
EP1397342A1 (en) * 2001-05-31 2004-03-17 Orion Corporation Fermion Process for preparing sertraline intermediates
US6723878B2 (en) 2001-06-15 2004-04-20 Orion Corporation Fermion Method for preparing sertraline
HUP0500215A2 (hu) * 2002-05-10 2005-06-28 Jirí Stohandl Eljárás szertralin előállítására
CA2522534A1 (en) * 2003-04-14 2004-10-28 Teva Pharmaceutical Industries Ltd. Hydrogenation of imine intermediates of sertraline with catalysts
HU227495B1 (en) * 2003-07-21 2011-07-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Process for producing of imine intermediate
TW200640836A (en) * 2005-02-23 2006-12-01 Teva Pharma Processes for preparing sertraline
WO2006129324A2 (en) * 2005-06-03 2006-12-07 Hetero Drugs Limited A highly stereoselective synthesis of sertraline
GB0526444D0 (en) * 2005-12-23 2006-02-08 Sandoz Ag Sertraline acid addition salt, its prepartion and its use in the preparation of sertraline hydrochloride form ll
US10266481B2 (en) * 2014-06-20 2019-04-23 Council Of Scientific & Industrial Research Organocatalytic asymmetric synthesis of antidepressants

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536518A (en) 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
US4855500A (en) 1988-05-04 1989-08-08 Pfizer Inc. Process for preparing a ketimine
US5196607A (en) * 1992-02-14 1993-03-23 Pfizer Inc. Process for preparing ketone enantiomer
HU226423B1 (en) 1998-05-05 2008-12-29 Egis Gyogyszergyar Nyrt Process for producing a 1(2h)-naphtalene-1-ylidene derivative

Also Published As

Publication number Publication date
CA2310799C (en) 2004-05-04
HUP0002229A2 (hu) 2002-04-29
JP2000351758A (ja) 2000-12-19
CN1277188A (zh) 2000-12-20
YU32700A (sh) 2002-03-18
RU2181358C2 (ru) 2002-04-20
IL136513A0 (en) 2001-06-14
JP3529703B2 (ja) 2004-05-24
EP1059287A1 (en) 2000-12-13
IL136513A (en) 2006-06-11
TR200001657A2 (tr) 2001-01-22
ID26278A (id) 2000-12-14
US6593496B1 (en) 2003-07-15
HU0002229D0 (en) 2000-08-28
PL340620A1 (en) 2000-12-18
AU3934500A (en) 2000-12-14
HUP0002229A3 (en) 2003-05-28
BR0002606A (pt) 2001-01-02
AU767319B2 (en) 2003-11-06
CA2310799A1 (en) 2000-12-09
KR20010066820A (ko) 2001-07-11

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