AR024435A1 - Toxinas de escorpion - Google Patents
Toxinas de escorpionInfo
- Publication number
- AR024435A1 AR024435A1 ARP000103111A ARP000103111A AR024435A1 AR 024435 A1 AR024435 A1 AR 024435A1 AR P000103111 A ARP000103111 A AR P000103111A AR P000103111 A ARP000103111 A AR P000103111A AR 024435 A1 AR024435 A1 AR 024435A1
- Authority
- AR
- Argentina
- Prior art keywords
- channel
- scorpion toxins
- chimeric gene
- modifier
- ancial
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43522—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from scorpions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Insects & Arthropods (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente se relaciona con un fragmento aislado de ácido nucleico que codifica toxinas de escorpion que son modificadoras de canales de Na. La presentese relaciona también con la construccion de un gen quimérico que codifica toda o una porcionsust ancial del modificador de canales de Na, en la orientacion delsentido del marco de lectura o antisentido, donde la expresion del gen quimérico da como resultado la produccion de niveles alterados de la proteína que medialos efectos delmodificador de canales de Na en la célula huésped transformada.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14041099P | 1999-06-22 | 1999-06-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR024435A1 true AR024435A1 (es) | 2002-10-02 |
Family
ID=22491107
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000103111A AR024435A1 (es) | 1999-06-22 | 2000-06-21 | Toxinas de escorpion |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1185653B1 (es) |
AR (1) | AR024435A1 (es) |
AT (1) | ATE406442T1 (es) |
AU (1) | AU5754200A (es) |
CA (1) | CA2372701A1 (es) |
DE (1) | DE60040067D1 (es) |
ES (1) | ES2312349T3 (es) |
WO (1) | WO2000078957A2 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003028666A2 (en) | 2001-10-04 | 2003-04-10 | The Regents Of The University Of California | Isolated polypeptides and compositions from the venom of p. transvaalicus and methods of use |
US7414173B1 (en) | 2002-07-12 | 2008-08-19 | E.I. Du Pont De Nemours And Company | Isolated nucleic acid molecules encoding orally active androctonus amoreuxi pesticidal biopeptides |
IL155972A0 (en) * | 2003-05-19 | 2003-12-23 | Yissum Res Dev Co | Cardiotonic polypeptides |
CN110055315A (zh) * | 2019-03-20 | 2019-07-26 | 中山大学 | 一种脑心通制剂中全蝎药材的dna分子鉴别方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9106185D0 (en) * | 1991-03-22 | 1991-05-08 | Wellcome Found | Biological control agents |
US5756340A (en) * | 1995-05-08 | 1998-05-26 | The Regents Of The University Of California | Insect control with multiple toxins |
NZ308772A (en) * | 1995-05-17 | 1999-04-29 | Du Pont | Recombinant baculovirus insecticides |
AU1227100A (en) * | 1998-10-23 | 2000-05-15 | E.I. Du Pont De Nemours And Company | Scorpion toxins |
-
2000
- 2000-06-21 AT AT00943005T patent/ATE406442T1/de not_active IP Right Cessation
- 2000-06-21 EP EP00943005A patent/EP1185653B1/en not_active Expired - Lifetime
- 2000-06-21 AU AU57542/00A patent/AU5754200A/en not_active Abandoned
- 2000-06-21 CA CA002372701A patent/CA2372701A1/en not_active Abandoned
- 2000-06-21 AR ARP000103111A patent/AR024435A1/es not_active Application Discontinuation
- 2000-06-21 ES ES00943005T patent/ES2312349T3/es not_active Expired - Lifetime
- 2000-06-21 WO PCT/US2000/017048 patent/WO2000078957A2/en active Application Filing
- 2000-06-21 DE DE60040067T patent/DE60040067D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO2000078957A3 (en) | 2001-05-03 |
EP1185653A2 (en) | 2002-03-13 |
CA2372701A1 (en) | 2000-12-28 |
ES2312349T3 (es) | 2009-03-01 |
WO2000078957A2 (en) | 2000-12-28 |
AU5754200A (en) | 2001-01-09 |
DE60040067D1 (es) | 2008-10-09 |
ATE406442T1 (de) | 2008-09-15 |
EP1185653B1 (en) | 2008-08-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |