AR023546A1 - Disulfuros ciclicos de pirrolidincarbonilamina - Google Patents
Disulfuros ciclicos de pirrolidincarbonilaminaInfo
- Publication number
- AR023546A1 AR023546A1 ARP000101825A ARP000101825A AR023546A1 AR 023546 A1 AR023546 A1 AR 023546A1 AR P000101825 A ARP000101825 A AR P000101825A AR P000101825 A ARP000101825 A AR P000101825A AR 023546 A1 AR023546 A1 AR 023546A1
- Authority
- AR
- Argentina
- Prior art keywords
- cyclic
- pirrolidincarbonylamine
- disulfures
- compounds
- cells
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000016289 Cell Adhesion Molecules Human genes 0.000 abstract 1
- 108010067225 Cell Adhesion Molecules Proteins 0.000 abstract 1
- -1 Cyclic disulfide compounds Chemical class 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000003038 endothelium Anatomy 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 102000006495 integrins Human genes 0.000 abstract 1
- 108010044426 integrins Proteins 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13021599P | 1999-04-20 | 1999-04-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR023546A1 true AR023546A1 (es) | 2002-09-04 |
Family
ID=22443611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000101825A AR023546A1 (es) | 1999-04-20 | 2000-04-19 | Disulfuros ciclicos de pirrolidincarbonilamina |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6265572B1 (https=) |
| EP (1) | EP1171452B1 (https=) |
| JP (1) | JP2002542256A (https=) |
| KR (1) | KR100636481B1 (https=) |
| CN (1) | CN1167710C (https=) |
| AR (1) | AR023546A1 (https=) |
| AT (1) | ATE337331T1 (https=) |
| AU (1) | AU769294B2 (https=) |
| BR (1) | BR0009838A (https=) |
| CA (1) | CA2370259A1 (https=) |
| DE (1) | DE60030266T2 (https=) |
| ES (1) | ES2269141T3 (https=) |
| TR (1) | TR200103004T2 (https=) |
| WO (1) | WO2000063234A2 (https=) |
| ZA (1) | ZA200108018B (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6939855B2 (en) | 1997-07-31 | 2005-09-06 | Elan Pharmaceuticals, Inc. | Anti-inflammatory compositions and method |
| CA2598816A1 (en) * | 2005-02-28 | 2006-08-31 | Medichem S.A. | Process and methods for the preparation of gabapentin and its intermediates |
| EP2124996A4 (en) | 2007-02-20 | 2010-03-24 | Merrimack Pharmaceuticals Inc | METHOD FOR TREATING MULTIPLE SCLEROSIS BY ADMINISTERING AN ALPHA FETOPROTEIN COMBINED WITH AN INTEGRINANT AGONIST |
| CA2721093A1 (en) | 2008-04-11 | 2009-10-15 | Merrimack Pharmaceuticals, Inc. | Human serum albumin linkers and conjugates thereof |
| CN102282168A (zh) | 2008-11-18 | 2011-12-14 | 梅里麦克制药股份有限公司 | 人血清白蛋白接头以及其结合物 |
| CA2850885A1 (en) | 2011-10-17 | 2013-04-25 | Westfaelische Wilhelms-Universitaet Muenster | Assessment of pml risk and methods based thereon |
| US20150202287A1 (en) | 2012-08-30 | 2015-07-23 | Merrimack Pharmaceuticals, Inc. | Combination therapies comprising anti-erbb3 agents |
| KR102659859B1 (ko) | 2018-10-30 | 2024-04-25 | 길리애드 사이언시즈, 인코포레이티드 | 알파4β7 인테그린의 억제를 위한 화합물 |
| AU2019373242B2 (en) | 2018-10-30 | 2023-07-13 | Gilead Sciences, Inc. | Compounds for inhibition of alpha 4 beta 7 integrin |
| EP4541422A3 (en) | 2018-10-30 | 2025-06-25 | Gilead Sciences, Inc. | Quinoline derivatives as alpha4beta7 integrin inhibitors |
| CN112969700B (zh) | 2018-10-30 | 2024-08-20 | 吉利德科学公司 | 作为α4β7整合素抑制剂的咪唑并吡啶衍生物 |
| KR102908219B1 (ko) | 2019-08-14 | 2026-01-08 | 길리애드 사이언시즈, 인코포레이티드 | 알파 4 베타 7 인테그린의 저해용 화합물 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5192746A (en) | 1990-07-09 | 1993-03-09 | Tanabe Seiyaku Co., Ltd. | Cyclic cell adhesion modulation compounds |
-
2000
- 2000-04-14 US US09/548,992 patent/US6265572B1/en not_active Expired - Fee Related
- 2000-04-17 WO PCT/EP2000/003459 patent/WO2000063234A2/en not_active Ceased
- 2000-04-17 EP EP00929365A patent/EP1171452B1/en not_active Expired - Lifetime
- 2000-04-17 DE DE60030266T patent/DE60030266T2/de not_active Expired - Fee Related
- 2000-04-17 CA CA002370259A patent/CA2370259A1/en not_active Abandoned
- 2000-04-17 AT AT00929365T patent/ATE337331T1/de not_active IP Right Cessation
- 2000-04-17 ES ES00929365T patent/ES2269141T3/es not_active Expired - Lifetime
- 2000-04-17 KR KR1020017013304A patent/KR100636481B1/ko not_active Expired - Fee Related
- 2000-04-17 JP JP2000612324A patent/JP2002542256A/ja active Pending
- 2000-04-17 AU AU47482/00A patent/AU769294B2/en not_active Ceased
- 2000-04-17 TR TR2001/03004T patent/TR200103004T2/xx unknown
- 2000-04-17 CN CNB008064601A patent/CN1167710C/zh not_active Expired - Fee Related
- 2000-04-17 BR BR0009838-8A patent/BR0009838A/pt not_active IP Right Cessation
- 2000-04-19 AR ARP000101825A patent/AR023546A1/es active IP Right Grant
-
2001
- 2001-09-28 ZA ZA200108018A patent/ZA200108018B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR0009838A (pt) | 2002-01-08 |
| EP1171452B1 (en) | 2006-08-23 |
| KR20010108517A (ko) | 2001-12-07 |
| AU4748200A (en) | 2000-11-02 |
| WO2000063234A3 (en) | 2001-01-18 |
| CA2370259A1 (en) | 2000-10-26 |
| US6265572B1 (en) | 2001-07-24 |
| EP1171452A2 (en) | 2002-01-16 |
| DE60030266T2 (de) | 2007-07-19 |
| TR200103004T2 (tr) | 2002-01-21 |
| AU769294B2 (en) | 2004-01-22 |
| ES2269141T3 (es) | 2007-04-01 |
| ATE337331T1 (de) | 2006-09-15 |
| DE60030266D1 (de) | 2006-10-05 |
| WO2000063234A2 (en) | 2000-10-26 |
| ZA200108018B (en) | 2003-03-26 |
| CN1347419A (zh) | 2002-05-01 |
| CN1167710C (zh) | 2004-09-22 |
| JP2002542256A (ja) | 2002-12-10 |
| KR100636481B1 (ko) | 2006-10-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |