AR020769A1 - Formulacion de champu estabilizada - Google Patents

Formulacion de champu estabilizada

Info

Publication number
AR020769A1
AR020769A1 ARP990105131A ARP990105131A AR020769A1 AR 020769 A1 AR020769 A1 AR 020769A1 AR P990105131 A ARP990105131 A AR P990105131A AR P990105131 A ARP990105131 A AR P990105131A AR 020769 A1 AR020769 A1 AR 020769A1
Authority
AR
Argentina
Prior art keywords
acrylate
formulation
stabilized shampoo
stabilized
copolymer
Prior art date
Application number
ARP990105131A
Other languages
English (en)
Original Assignee
Colgate Palmolive Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26800897&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR020769(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Colgate Palmolive Co filed Critical Colgate Palmolive Co
Publication of AR020769A1 publication Critical patent/AR020769A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/342Alcohols having more than seven atoms in an unbroken chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • A61K8/416Quaternary ammonium compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • A61K8/894Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by a polyoxyalkylene group, e.g. cetyl dimethicone copolyol

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Composiciones de champu mejoradas y estabilizadas que contienen materiales de siloxisilicato comunmente llamados resinas MQ, donde los estabilizadores sonseleccionados de (i) alcoholes grasos de cadena larga con más de 14 C; (ii) copolímero de acrilatos/estearet-20 metacrilato; copolímero de acrilatos; yacrilatos/polímero cruzado alquilo acrilato C10-30; y (iii) ácidos ftalámicos N,N-disustituidos seleccionados y sus sales de amonio.
ARP990105131A 1998-10-09 1999-10-08 Formulacion de champu estabilizada AR020769A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10383098P 1998-10-09 1998-10-09
US09/406,543 US6287546B1 (en) 1998-10-09 1999-09-27 Shampoos with stabilizers

Publications (1)

Publication Number Publication Date
AR020769A1 true AR020769A1 (es) 2002-05-29

Family

ID=26800897

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990105131A AR020769A1 (es) 1998-10-09 1999-10-08 Formulacion de champu estabilizada

Country Status (21)

Country Link
US (1) US6287546B1 (es)
EP (1) EP1119339B1 (es)
CN (1) CN1245949C (es)
AR (1) AR020769A1 (es)
AT (1) ATE374058T1 (es)
AU (1) AU766097B2 (es)
BR (1) BR9914338B1 (es)
CO (1) CO5150212A1 (es)
CZ (1) CZ20011273A3 (es)
DE (1) DE69937195T2 (es)
GT (1) GT199900175A (es)
HK (1) HK1037533A1 (es)
MA (1) MA25001A1 (es)
NO (1) NO20011747L (es)
NZ (1) NZ511038A (es)
PL (1) PL347893A1 (es)
RU (1) RU2232010C2 (es)
SK (1) SK4652001A3 (es)
TR (1) TR200101805T2 (es)
TW (1) TW589192B (es)
WO (1) WO2000021494A1 (es)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150313A (en) * 1999-08-18 2000-11-21 Colgate-Palmolive Company Skin cleansing composition comprising a mixture of thickening polymers
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
JP3590759B2 (ja) * 2000-07-03 2004-11-17 株式会社巴川製紙所 静電荷像現像用トナーおよび二成分現像剤
US7070769B2 (en) 2001-02-16 2006-07-04 L'oreal Compositions comprising at least two anionic associative polymers and their use for stabilization of an oxidizing solution
US6774175B2 (en) 2001-02-16 2004-08-10 L'oreal S.A. Stabilizing compositions comprising at least two anionic associative polymers, their use for stabilization of non-solid compositions, and compositions comprising at least one stabilizing composition
WO2003026599A1 (en) * 2001-09-26 2003-04-03 The Procter & Gamble Company Personal cleansing compositions comprising silicone resin-containing adhesives
US7176170B2 (en) 2002-05-31 2007-02-13 L'oreal Shampoo comprising at least one silicone and at least one anionic or nonionic, amphiphilic linear block copolymer
FR2840206B1 (fr) * 2002-05-31 2005-08-05 Oreal Shampooing contenant au moins une silicone et au moins un copolymere lineaire sequence amphiphile, anionique ou non- ionique
WO2004037225A2 (en) 2002-10-25 2004-05-06 Foamix Ltd. Cosmetic and pharmaceutical foam
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US8486376B2 (en) * 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US20060079415A1 (en) * 2004-10-13 2006-04-13 Cheryl Kozubal Conditioning shampoos with detergent soluble silicones
US20060115439A1 (en) * 2004-11-04 2006-06-01 L'oreal Compositions containing at least one silicone resin and glass beads
WO2007054818A2 (en) 2005-05-09 2007-05-18 Foamix Ltd. Foamable vehicle and pharmaceutical compositions thereof
US20070148101A1 (en) * 2005-12-28 2007-06-28 Marcia Snyder Foamable alcoholic composition
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
EP2011471A1 (en) * 2007-07-02 2009-01-07 Johnson & Johnson Consumer France SAS Foaming oil compositions
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A2 (en) 2007-11-30 2009-06-04 Foamix Ltd. Foam containing benzoyl peroxide
WO2010041141A2 (en) 2008-10-07 2010-04-15 Foamix Ltd. Oil-based foamable carriers and formulations
WO2009090495A2 (en) 2007-12-07 2009-07-23 Foamix Ltd. Oil and liquid silicone foamable carriers and formulations
CA2712120A1 (en) 2008-01-14 2009-07-23 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
US20100015078A1 (en) * 2008-07-18 2010-01-21 Yujun Li Conditioning composition comprising dual cationic surfactant system, aminosilicone and silicone resin
EA201170999A1 (ru) * 2009-02-04 2012-01-30 Унилевер Н.В. Композиции для обработки волос
WO2010125470A2 (en) 2009-04-28 2010-11-04 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
CA2769677A1 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
WO2011013009A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
WO2011064631A1 (en) 2009-10-02 2011-06-03 Foamix Ltd. Surfactant-free, water-free, foamable compositions and breakable foams and their uses
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
DE102010041887A1 (de) 2010-10-01 2012-04-05 Beiersdorf Ag Pflegeprodukte zum Schützen colorierter Haare mit Silikonharzen
WO2012150259A1 (en) * 2011-05-04 2012-11-08 Unilever Plc Composition
DE102012206948A1 (de) * 2012-04-26 2013-10-31 Henkel Ag & Co. Kgaa Haarbehandlungsmittel mit hydroxy-terminierten Organopolysiloxan(en) und Verdickungsmittel(n)
DE102014210575A1 (de) 2014-06-04 2015-12-17 Beiersdorf Ag Kosmetische Shampoos mit einem Gehalt an in Silikonöl dispergierten Silikonharzen
WO2016100634A2 (en) 2014-12-19 2016-06-23 The Procter & Gamble Company Composition for enhancing hair fiber properties
WO2017132308A1 (en) 2016-01-29 2017-08-03 The Procter & Gamble Company Composition for enhancing hair fiber properties
US10398641B2 (en) 2016-09-08 2019-09-03 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne
US11116220B2 (en) 2017-12-22 2021-09-14 Ecolab Usa Inc. Antimicrobial compositions with enhanced efficacy

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2528378A (en) 1947-09-20 1950-10-31 John J Mccabe Jr Metal salts of substituted quaternary hydroxy cycloimidinic acid metal alcoholates and process for preparation of same
GB1425228A (en) 1973-02-12 1976-02-18 Gillette Co Hair sprays and setting lotions
US4012501A (en) 1975-05-08 1977-03-15 La Maur Inc. Hair-care composition containing a thermoplastic polymer
US4223009A (en) 1977-06-10 1980-09-16 Gaf Corporation Hair preparation containing vinyl pyrrolidone copolymer
CA1261276A (en) 1984-11-09 1989-09-26 Mark B. Grote Shampoo compositions
US4902499A (en) 1986-04-04 1990-02-20 The Procter & Gamble Company Hair care compositions containing a rigid silicone polymer
GB8615862D0 (en) 1986-06-28 1986-08-06 Dow Corning Ltd Making siloxane resins
US4728457A (en) 1986-08-25 1988-03-01 The Proctor & Gamble Company Process for making a silicone-containing shampoo
US4963348A (en) 1987-12-11 1990-10-16 The Procter & Gamble Company Styling agents and compositions containing the same
US5015415A (en) 1990-06-27 1991-05-14 Goze Jean M N,N-disubstituted phthalamic acids and their ammonium salts, and their uses thereof as surfactants, emulsifiers, and conditioning agents in shampoos
GB2245279B (en) 1990-06-20 1993-04-07 Unilever Plc Shampoo composition
US5075103A (en) * 1990-07-06 1991-12-24 Dow Corning Corporation Hair fixatives comprising nonpolar silsesquioxanes
CZ281812B6 (cs) 1990-12-05 1997-02-12 The Procter And Gamble Company Vlasový šamponový kondicionér se silikonovým kondicionačním činidlem
WO1992010163A1 (en) 1990-12-05 1992-06-25 The Procter & Gamble Company Shampoo compositions with silicone and cationic surfactant conditioning agents
BR9205839A (pt) 1991-04-05 1994-09-27 Procter & Gamble Composiçoes de shampoo condicionador de cabelos com agente de condicionamento de silicone.
EP0665740A1 (en) 1992-10-22 1995-08-09 The Procter & Gamble Company Hair care compositions providing conditioning and enhanced shine
DE19603357B4 (de) 1995-02-10 2004-09-23 General Electric Co. Siloxysilicatharze geringer Viskosität mit organischen, funktionellen Gruppen

Also Published As

Publication number Publication date
CN1245949C (zh) 2006-03-22
CN1329480A (zh) 2002-01-02
ATE374058T1 (de) 2007-10-15
CZ20011273A3 (cs) 2001-09-12
MA25001A1 (fr) 2000-07-01
BR9914338A (pt) 2001-06-26
EP1119339A1 (en) 2001-08-01
PL347893A1 (en) 2002-04-22
TR200101805T2 (tr) 2001-12-21
NO20011747D0 (no) 2001-04-06
WO2000021494A1 (en) 2000-04-20
NO20011747L (no) 2001-06-05
BR9914338B1 (pt) 2013-11-19
NZ511038A (en) 2003-08-29
AU766097B2 (en) 2003-10-09
SK4652001A3 (en) 2001-12-03
CO5150212A1 (es) 2002-04-29
RU2232010C2 (ru) 2004-07-10
GT199900175A (es) 2001-03-31
US6287546B1 (en) 2001-09-11
DE69937195D1 (de) 2007-11-08
HK1037533A1 (en) 2002-02-15
TW589192B (en) 2004-06-01
DE69937195T2 (de) 2008-06-26
AU6296299A (en) 2000-05-01
EP1119339B1 (en) 2007-09-26

Similar Documents

Publication Publication Date Title
AR020769A1 (es) Formulacion de champu estabilizada
TR199700660T1 (xx) Yeni farnezil transferaz �nleyiciler.
CU23174A3 (es) Regulacion de la expresion de quinolato fosforribosil transferasa
ES2054278T3 (es) Utilizacion y composiciones cosmeticas que contienen diorganopolisiloxanos con funcion benzotriazol para la proteccion de la piel y los cabellos.
FI943260A0 (fi) Vedenkestävä, irrotettava, paineherkkä tarra akryyliemulsiosta
MX9305798A (es) Composiciones de lapiz labial humedecedor.
ATE105174T1 (de) Silicone enthaltende haarfixierungsmittel.
CU22772A3 (es) Suplementos alimenticios que contienen flavonol
KR930002478A (ko) 가역성 열변색 재료
ES2196569T3 (es) Composicion cosmetica mejorada que contiene esteres de acido ferulico.
ATE254443T1 (de) Inhibitierung des haarwuchses
ES2168247T3 (es) Composicion cosmetica que comprende la asociacion de un ester particular y de un compuesto silicona.
ES2100560T3 (es) Formulaciones cosmeticas y dermatologicas de proteccion solar que contienen tioles y/o derivados de tiol.
PT879814E (pt) Compostos tri-aromaticos composicoes que os contem e utilizacoes
FR2737115B1 (fr) Composition stable contenant une enzyme
DE59802529D1 (de) Kosmetische pit-emulsionen
DE69433824T2 (de) Kosmetische Zusammensetzungen enthaltend Hydroxyalkanoat Derivate
TR199801823T2 (en) B�cek �ld�r�c� kar���mlar.
DE69624223T2 (de) Imidazolidinonderivate als korrosionsinhibitoren
ES2114849T1 (es) Producto y procedimiento para el moldeado permanente del cabello.
AR009819A1 (es) Inhibidores de la proteasa proteinicos estabilizados y sus variantes
DE69006345D1 (de) Totale Synthese von Erbstatin-Analogen.
ES2164820T3 (es) Emulsiones cosmeticas y/o farmaceuticas.
PA8483801A1 (es) Champues mejorados con estabilizadores
KR960700684A (ko) 화장용 조성물(cosmetic)

Legal Events

Date Code Title Description
FA Abandonment or withdrawal