AR013255A1 - Disposicion de descarga osmotica, metodo para ensamblar la disposicion de descarga osmotica, metodo para descargar un agente benefico hacia adentro de la disposicion de descarga osmotica y metodo para armar la disposicion de descarga osmotica - Google Patents
Disposicion de descarga osmotica, metodo para ensamblar la disposicion de descarga osmotica, metodo para descargar un agente benefico hacia adentro de la disposicion de descarga osmotica y metodo para armar la disposicion de descarga osmoticaInfo
- Publication number
- AR013255A1 AR013255A1 ARP980103661A ARP980103661A AR013255A1 AR 013255 A1 AR013255 A1 AR 013255A1 AR P980103661 A ARP980103661 A AR P980103661A AR P980103661 A ARP980103661 A AR P980103661A AR 013255 A1 AR013255 A1 AR 013255A1
- Authority
- AR
- Argentina
- Prior art keywords
- osmotic
- discharge
- provision
- assembling
- osmotic discharge
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/141—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor with capillaries for restricting fluid flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14526—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons the piston being actuated by fluid pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16804—Flow controllers
- A61M5/16813—Flow controllers by controlling the degree of opening of the flow line
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/494—Fluidic or fluid actuated device making
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Dicing (AREA)
- Packages (AREA)
- Respiratory Apparatuses And Protective Means (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- External Artificial Organs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
Una disposicion de descarga osmotica con un conjunto modulador de flujo, un método para ensamblar una disposicion de descarga osmotica, método paradescargar un agente benéfico hacia adentro de la disposicion de descarga osmotica y método paraarmar la disposicion de descarga osmotica. El conjuntomodulador de flujo de disposicion de descarga osmotica incluye un cuerpo que tiene un agujero ubicado a través del cuerpo, y que comunica dos extremosopuestos del cuerpo. El uso del conjuntomo dulador de flujo de disposicion de descarga osmotica disminuye la posibilidad que bolsillos de gas o de aire seformen en el recinto de la disposicion de descarga osmotica durante el ensamblaje de la disposicion. Debido a que menos aireest á adentro de ladisposicion de descarga osmotica, se mejora el funcionamiento de la disposicion. El uso del conjunto modulador de flujo también disminuye laposibilidad que se despedicie el agente benéfico durante el ensamblaje de ladis posicion de descarga osmotica.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5369097P | 1997-07-25 | 1997-07-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR013255A1 true AR013255A1 (es) | 2000-12-13 |
Family
ID=21985903
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP980103661A AR013255A1 (es) | 1997-07-25 | 1998-07-24 | Disposicion de descarga osmotica, metodo para ensamblar la disposicion de descarga osmotica, metodo para descargar un agente benefico hacia adentro de la disposicion de descarga osmotica y metodo para armar la disposicion de descarga osmotica |
Country Status (19)
Country | Link |
---|---|
US (4) | US6524305B1 (es) |
EP (1) | EP0998273B1 (es) |
JP (1) | JP2001510792A (es) |
KR (1) | KR100523201B1 (es) |
CN (1) | CN1198601C (es) |
AR (1) | AR013255A1 (es) |
AT (1) | ATE276747T1 (es) |
AU (1) | AU8493898A (es) |
CA (1) | CA2297817C (es) |
CO (1) | CO4890860A1 (es) |
DE (1) | DE69826479T2 (es) |
DK (1) | DK0998273T3 (es) |
ES (1) | ES2226159T3 (es) |
HK (1) | HK1027752A1 (es) |
MY (1) | MY125870A (es) |
PT (1) | PT998273E (es) |
TW (1) | TW384226B (es) |
WO (1) | WO1999004768A2 (es) |
ZA (1) | ZA986629B (es) |
Families Citing this family (79)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6440457B1 (en) * | 1993-05-27 | 2002-08-27 | Alza Corporation | Method of administering antidepressant dosage form |
MY125870A (en) * | 1997-07-25 | 2006-08-30 | Alza Corp | Osmotic delivery system flow modulator apparatus and method |
US6764461B2 (en) * | 1997-12-01 | 2004-07-20 | Scimed Life Systems, Inc. | Catheter system for the delivery of a low volume bolus |
US7258869B1 (en) | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
US7919109B2 (en) | 1999-02-08 | 2011-04-05 | Intarcia Therapeutics, Inc. | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles |
US6541021B1 (en) * | 1999-03-18 | 2003-04-01 | Durect Corporation | Devices and methods for pain management |
US6835194B2 (en) * | 1999-03-18 | 2004-12-28 | Durect Corporation | Implantable devices and methods for treatment of pain by delivery of fentanyl and fentanyl congeners |
US7074803B2 (en) * | 2001-03-02 | 2006-07-11 | Durect Corporation | Opioid formulations |
US7163688B2 (en) * | 2001-06-22 | 2007-01-16 | Alza Corporation | Osmotic implant with membrane and membrane retention means |
KR100439197B1 (ko) * | 2001-08-22 | 2004-07-07 | 주식회사 꾼커뮤니케이션 | 다중 프로토콜을 이용한 서버 데이터 분산 방법 |
EP1435919B1 (en) * | 2001-09-17 | 2009-09-23 | Durect Corporation | Device and method for accurate delivery of an active agent |
CA2489325C (en) * | 2002-06-17 | 2010-08-10 | Alza Corporation | Osmotic delivery system with early zero order push power engine comprising an osmotic agent dispersed in the fluid vehicle |
KR101046903B1 (ko) * | 2002-06-26 | 2011-07-06 | 인타르시아 세라퓨틱스 인코포레이티드 | 삼투성 약물 전달 시스템을 위한, 최소로 튀는 용적효율성 피스톤 |
US7235164B2 (en) | 2002-10-18 | 2007-06-26 | Eksigent Technologies, Llc | Electrokinetic pump having capacitive electrodes |
JP2006512370A (ja) * | 2002-12-19 | 2006-04-13 | アルザ・コーポレーション | 安定な非水性単相ゲル、および植込み型デバイスから送達するためのその配合物 |
US7731947B2 (en) * | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
JP2006521897A (ja) * | 2003-03-31 | 2006-09-28 | アルザ・コーポレーション | 内部圧力を放散する手段を備える浸透ポンプ |
MXPA05010604A (es) * | 2003-03-31 | 2005-11-23 | Alza Corp | Sistema de administracion osmotica y metodo para disminuir los tiempos de arranque para sistemas de administracion osmotica. |
TW200505500A (en) * | 2003-03-31 | 2005-02-16 | Alza Corp | Non-aqueous single phase vehicles and formulations utilizing such vehicles |
US6976983B2 (en) * | 2003-06-12 | 2005-12-20 | Cordis Corporation | Implantable device for delivering drugs using orifice mechanism capable of low fluid flow rates |
US7211076B2 (en) | 2003-06-12 | 2007-05-01 | Cordis Corporation | Medical device for fluid delivery having low fluid flow rate |
US8491571B2 (en) * | 2003-06-12 | 2013-07-23 | Cordis Corporation | Orifice device having multiple channels with varying flow rates for drug delivery |
US7678103B2 (en) * | 2003-06-12 | 2010-03-16 | Cordis Corporation | Orifice device for delivering drugs at low fluid flow rates |
US7108762B2 (en) * | 2003-06-12 | 2006-09-19 | Cordis Corporation | Method for manufacturing an orifice mechanism capable of low fluid flow rates |
US8109922B2 (en) * | 2003-06-12 | 2012-02-07 | Cordis Corporation | Orifice device having multiple channels and multiple layers for drug delivery |
WO2005007223A2 (en) * | 2003-07-16 | 2005-01-27 | Sasha John | Programmable medical drug delivery systems and methods for delivery of multiple fluids and concentrations |
RU2006118808A (ru) * | 2003-10-31 | 2007-12-10 | Алза Корпорейшн (Us) | Осмотический насос с самоудерживающейся, выполненной с возможностью быстрого пуска мембранной пробкой |
RU2006119632A (ru) * | 2003-11-06 | 2007-12-20 | Алза Корпорейшн (Us) | Модульный ограничитель скорости впитывания для использования с имплантируемым осмотическим насосом |
US20050232972A1 (en) * | 2004-04-15 | 2005-10-20 | Steven Odrich | Drug delivery via punctal plug |
US20050266087A1 (en) * | 2004-05-25 | 2005-12-01 | Gunjan Junnarkar | Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium |
EP3470108A1 (en) * | 2004-07-02 | 2019-04-17 | Mati Therapeutics Inc. | Treatment medium delivery device for delivery of treatment media to the eye |
JP2007321769A (ja) * | 2005-02-01 | 2007-12-13 | Thk Co Ltd | レール取付孔の閉塞構造 |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
EP2361630A1 (en) * | 2005-02-03 | 2011-08-31 | Intarcia Therapeutics, Inc | Implantable drug delivery device comprising particles and an osmotic pump |
WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
US7959938B2 (en) * | 2005-03-15 | 2011-06-14 | Intarcia Therapeutics, Inc. | Polyoxaester suspending vehicles for use with implantable delivery systems |
US20080312587A1 (en) * | 2005-06-10 | 2008-12-18 | Gruenethal Gmbh | System for the Oral Administration of Solids to Persons Suffering from Dementia |
WO2007013957A2 (en) * | 2005-07-22 | 2007-02-01 | University Of Utah Research Foundation | Osmotically driven dispense pump and related components for use in high pressure applications |
US20070027105A1 (en) * | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
EP2182078B1 (en) * | 2005-09-01 | 2012-02-01 | Bristol-Myers Squibb Company | Biomarkers and methods for determining sensitivity to vascular endothelial growth factor receptor-2 modulators |
DK1957794T3 (da) * | 2005-11-23 | 2014-08-11 | Eksigent Technologies Llc | Elektrokinetiske pumpeudformninger og lægemiddelfremføringssystemer |
US20070163968A1 (en) * | 2006-01-17 | 2007-07-19 | Johnsondiversey, Inc. | Method and apparatus for providing treatment chemicals to process water systems |
BRPI0709672B8 (pt) | 2006-03-31 | 2021-06-22 | 3088922 Inc | implante ocular insersível em um lúmen ocular e método de distribuição de um agente terapêutico a um olho |
KR101106510B1 (ko) * | 2006-05-30 | 2012-01-20 | 인타르시아 세라퓨틱스 인코포레이티드 | 투피스, 내부채널 삼투압 전달 시스템 유동 조절기 |
AU2007284759B2 (en) | 2006-08-09 | 2010-10-28 | Intarcia Therapeutics, Inc. | Osmotic delivery systems and piston assemblies |
US7538652B2 (en) * | 2006-08-29 | 2009-05-26 | International Business Machines Corporation | Electrical component tuned by conductive layer deletion |
RU2440097C2 (ru) | 2007-04-23 | 2012-01-20 | Интарсия Терапьютикс, Инк. | Способ лечения диабета ii типа и ожирения, осмотическое устройство для доставки и способ его изготовления |
EP2865361B1 (en) | 2007-09-07 | 2019-05-22 | Mati Therapeutics Inc. | Lacrimal implants and related methods |
AU2008300022A1 (en) | 2007-09-07 | 2009-03-19 | Qlt Inc. | Lacrimal implant detection |
DK2207529T3 (en) | 2007-09-07 | 2015-03-09 | Mati Therapeutics Inc | PHARMACEUTICAL cores for the sustained release of therapeutic agents |
KR20100058620A (ko) * | 2007-09-07 | 2010-06-03 | 큐엘티 플러그 딜리버리, 인코포레이티드 | 눈물 임플랜트용 삽입 및 적출 기구 |
EP2060286B1 (en) * | 2007-11-13 | 2011-01-12 | Acuros GmbH | Osmotic pump |
DK2240155T3 (da) | 2008-02-13 | 2012-09-17 | Intarcia Therapeutics Inc | Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler |
WO2009105178A2 (en) * | 2008-02-18 | 2009-08-27 | Qlt Plug Delivery, Inc. | Lacrimal implants and related methods |
CN104623741A (zh) | 2008-04-30 | 2015-05-20 | 马缇医疗股份有限公司 | 复合泪管植入物及相关方法 |
JP2011520805A (ja) * | 2008-05-09 | 2011-07-21 | キューエルティー プラグ デリバリー,インク. | 緑内障および高眼圧症治療のための活性剤の持続送達 |
US8834446B2 (en) * | 2008-06-12 | 2014-09-16 | DePuy Synthes Products, LLC | Pulsatile flux drug delivery |
NZ592113A (en) * | 2008-10-15 | 2012-04-27 | Intarcia Therapeutics Inc | Highly concentrated drug particles, formulations, suspensions and uses thereof |
WO2010096822A2 (en) * | 2009-02-23 | 2010-08-26 | Qlt Plug Delivery, Inc. | Lacrimal implants and related methods |
CN102378637B (zh) * | 2009-04-07 | 2014-12-24 | 皇家飞利浦电子股份有限公司 | 无阀给药装置 |
FR2944292B1 (fr) | 2009-04-08 | 2013-08-23 | Sanofi Pasteur | Procede de purification du virus rabique |
EP3735944A1 (en) | 2009-09-28 | 2020-11-11 | Intarcia Therapeutics, Inc. | Rapid establishment and/or termination of substantial steady-state drug delivery |
US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
EP2704759A4 (en) | 2011-05-05 | 2015-06-03 | Eksigent Technologies Llc | COUPLING GEL FOR ELECTROCINETIC FLUID DISTRIBUTION SYSTEMS |
US9974685B2 (en) | 2011-08-29 | 2018-05-22 | Mati Therapeutics | Drug delivery system and methods of treating open angle glaucoma and ocular hypertension |
EP3290024B1 (en) | 2011-08-29 | 2019-04-17 | Mati Therapeutics Inc. | Sustained release delivery of active agents to treat glaucoma and ocular hypertension |
WO2014102741A2 (en) * | 2012-12-28 | 2014-07-03 | University Of The Witwatersrand, Johannesburg | Pharmaceutical dosage form |
KR20160083061A (ko) * | 2013-11-05 | 2016-07-11 | 타리스 바이오메디컬 엘엘씨 | 삼투 약물 전달 디바이스들, 키트, 및 방법들 |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
MA44390A (fr) | 2015-06-03 | 2019-01-23 | Intarcia Therapeutics Inc | Systèmes de mise en place et de retrait d'implant |
WO2017200943A1 (en) | 2016-05-16 | 2017-11-23 | Intarcia Therapeutics, Inc. | Glucagon-receptor selective polypeptides and methods of use thereof |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
US10406336B2 (en) | 2016-08-03 | 2019-09-10 | Neil S. Davey | Adjustable rate drug delivery implantable device |
IL267736B2 (en) | 2017-01-03 | 2024-03-01 | Intarcia Therapeutics Inc | Methods involving continuous administration of a GLP-1 receptor agonist and co-administration of a drug |
KR102455451B1 (ko) * | 2017-09-07 | 2022-10-18 | 하이퍼바릭, 에스.에이. | 고압 처리를 위한 플러그, 기계, 및 방법 |
USD933219S1 (en) | 2018-07-13 | 2021-10-12 | Intarcia Therapeutics, Inc. | Implant removal tool and assembly |
KR20220140711A (ko) | 2020-01-13 | 2022-10-18 | 듀렉트 코퍼레이션 | 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법 |
WO2023181996A1 (ja) * | 2022-03-25 | 2023-09-28 | テルモ株式会社 | 投与装置 |
Family Cites Families (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3995631A (en) | 1971-01-13 | 1976-12-07 | Alza Corporation | Osmotic dispenser with means for dispensing active agent responsive to osmotic gradient |
US3732865A (en) | 1971-01-13 | 1973-05-15 | Alza Corp | Osmotic dispenser |
US3995632A (en) | 1973-05-04 | 1976-12-07 | Alza Corporation | Osmotic dispenser |
US3831813A (en) * | 1973-05-11 | 1974-08-27 | Haemonetics Corp | High-flow capacity, self-regulating bypass spike |
US4111202A (en) | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system for the controlled and delivery of agent over time |
US4243030A (en) | 1978-08-18 | 1981-01-06 | Massachusetts Institute Of Technology | Implantable programmed microinfusion apparatus |
US4373527B1 (en) | 1979-04-27 | 1995-06-27 | Univ Johns Hopkins | Implantable programmable medication infusion system |
US4320758A (en) * | 1979-05-07 | 1982-03-23 | Alza Corporation | Osmotically driven fluid dispenser |
US4340054A (en) | 1980-12-29 | 1982-07-20 | Alza Corporation | Dispenser for delivering fluids and solids |
US4439196A (en) | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
US4552561A (en) | 1982-12-23 | 1985-11-12 | Alza Corporation | Body mounted pump housing and pump assembly employing the same |
US4639244A (en) | 1983-05-03 | 1987-01-27 | Nabil I. Rizk | Implantable electrophoretic pump for ionic drugs and associated methods |
US4747847A (en) * | 1986-02-07 | 1988-05-31 | Alza Corporation | System for delivering potassium chloride with enhanced bioacceptability |
US4865845A (en) | 1986-03-21 | 1989-09-12 | Alza Corporation | Release rate adjustment of osmotic or diffusional delivery devices |
JPH0772799B2 (ja) | 1986-08-13 | 1995-08-02 | ソニー株式会社 | レジスト材料 |
US5106627A (en) * | 1987-11-17 | 1992-04-21 | Brown University Research Foundation | Neurological therapy devices |
DE69003805T2 (de) * | 1989-11-13 | 1994-05-19 | Becton Dickinson France | Vorratsbehälter für einen bestandteil einer medikamentenlösung. |
US5474785A (en) * | 1990-01-24 | 1995-12-12 | Alza Corporation | Delivery system comprising means for controlling internal pressure |
US5151093A (en) | 1990-10-29 | 1992-09-29 | Alza Corporation | Osmotically driven syringe with programmable agent delivery |
GB9027422D0 (en) | 1990-12-18 | 1991-02-06 | Scras | Osmotically driven infusion device |
US5223265A (en) | 1992-01-10 | 1993-06-29 | Alza Corporation | Osmotic device with delayed activation of drug delivery |
US5308348A (en) | 1992-02-18 | 1994-05-03 | Alza Corporation | Delivery devices with pulsatile effect |
US5456679A (en) | 1992-02-18 | 1995-10-10 | Alza Corporation | Delivery devices with pulsatile effect |
GB9223146D0 (en) | 1992-11-05 | 1992-12-16 | Scherer Corp R P | Vented capsule |
US5431919A (en) * | 1993-06-23 | 1995-07-11 | Alza | Ruminal drug delivery device |
US5690952A (en) * | 1995-06-07 | 1997-11-25 | Judy A. Magruder et al. | Implantable system for delivery of fluid-sensitive agents to animals |
US5904935A (en) * | 1995-06-07 | 1999-05-18 | Alza Corporation | Peptide/protein suspending formulations |
US6132420A (en) * | 1996-02-02 | 2000-10-17 | Alza Corporation | Osmotic delivery system and method for enhancing start-up and performance of osmotic delivery systems |
PT877599E (pt) | 1996-02-02 | 2003-08-29 | Alza Corp | Administracao continua de leuprolido utilizando um sistema implantavel |
US5932547A (en) * | 1996-07-03 | 1999-08-03 | Alza Corporation | Non-aqueous polar aprotic peptide formulations |
ZA981610B (en) * | 1997-03-24 | 1999-08-26 | Alza Corp | Self adjustable exit port. |
US5996586A (en) * | 1997-03-26 | 1999-12-07 | Phillips; Michael | Breath test for detection of lung cancer |
MY125849A (en) * | 1997-07-25 | 2006-08-30 | Alza Corp | Osmotic delivery system, osmotic delivery system semipermeable body assembly, and method for controlling delivery rate of beneficial agents from osmotic delivery systems |
MY125870A (en) * | 1997-07-25 | 2006-08-30 | Alza Corp | Osmotic delivery system flow modulator apparatus and method |
JP4215188B2 (ja) * | 1997-12-22 | 2009-01-28 | インターシア セラピューティクス,インコーポレイティド | 薬剤供給を調節するデバイスのための速度調節膜 |
AU1828599A (en) * | 1997-12-29 | 1999-07-19 | Alza Corporation | Osmotic delivery system with membrane plug retention mechanism |
EP1041974B1 (en) * | 1997-12-30 | 2006-10-11 | Alza Corporation | Beneficial agent delivery system with membrane plug |
DE69906132T2 (de) * | 1998-12-31 | 2003-12-18 | Alza Corp., Mountain View | Osmotisches verabreichungsystem mit raumsparenden kolben |
US7258869B1 (en) * | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
DE60023361T2 (de) * | 1999-12-21 | 2006-04-27 | Alza Corp., Mountain View | Ventil für osmotische vorrichtungen |
US7163688B2 (en) * | 2001-06-22 | 2007-01-16 | Alza Corporation | Osmotic implant with membrane and membrane retention means |
CA2489325C (en) * | 2002-06-17 | 2010-08-10 | Alza Corporation | Osmotic delivery system with early zero order push power engine comprising an osmotic agent dispersed in the fluid vehicle |
KR101046903B1 (ko) * | 2002-06-26 | 2011-07-06 | 인타르시아 세라퓨틱스 인코포레이티드 | 삼투성 약물 전달 시스템을 위한, 최소로 튀는 용적효율성 피스톤 |
US7014636B2 (en) * | 2002-11-21 | 2006-03-21 | Alza Corporation | Osmotic delivery device having a two-way valve and a dynamically self-adjusting flow channel |
US7731947B2 (en) * | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
JP2006512370A (ja) * | 2002-12-19 | 2006-04-13 | アルザ・コーポレーション | 安定な非水性単相ゲル、および植込み型デバイスから送達するためのその配合物 |
TW200505500A (en) * | 2003-03-31 | 2005-02-16 | Alza Corp | Non-aqueous single phase vehicles and formulations utilizing such vehicles |
JP2006521897A (ja) * | 2003-03-31 | 2006-09-28 | アルザ・コーポレーション | 内部圧力を放散する手段を備える浸透ポンプ |
US20050175701A1 (en) * | 2004-02-10 | 2005-08-11 | Alza Corporation | Capillary moderator for osmotic delivery system |
US20050266087A1 (en) * | 2004-05-25 | 2005-12-01 | Gunjan Junnarkar | Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium |
WO2006083761A2 (en) * | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
US20060216242A1 (en) * | 2005-02-03 | 2006-09-28 | Rohloff Catherine M | Suspending vehicles and pharmaceutical suspensions for drug dosage forms |
US7959938B2 (en) * | 2005-03-15 | 2011-06-14 | Intarcia Therapeutics, Inc. | Polyoxaester suspending vehicles for use with implantable delivery systems |
US20070027105A1 (en) * | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
KR101106510B1 (ko) * | 2006-05-30 | 2012-01-20 | 인타르시아 세라퓨틱스 인코포레이티드 | 투피스, 내부채널 삼투압 전달 시스템 유동 조절기 |
-
1998
- 1998-07-23 MY MYPI98003365A patent/MY125870A/en unknown
- 1998-07-24 CN CNB988075229A patent/CN1198601C/zh not_active Expired - Fee Related
- 1998-07-24 KR KR10-2000-7000796A patent/KR100523201B1/ko not_active IP Right Cessation
- 1998-07-24 DK DK98935754T patent/DK0998273T3/da active
- 1998-07-24 WO PCT/US1998/014813 patent/WO1999004768A2/en active IP Right Grant
- 1998-07-24 AT AT98935754T patent/ATE276747T1/de not_active IP Right Cessation
- 1998-07-24 DE DE69826479T patent/DE69826479T2/de not_active Expired - Fee Related
- 1998-07-24 PT PT98935754T patent/PT998273E/pt unknown
- 1998-07-24 CO CO98042277A patent/CO4890860A1/es unknown
- 1998-07-24 CA CA002297817A patent/CA2297817C/en not_active Expired - Fee Related
- 1998-07-24 ES ES98935754T patent/ES2226159T3/es not_active Expired - Lifetime
- 1998-07-24 TW TW087112138A patent/TW384226B/zh not_active IP Right Cessation
- 1998-07-24 ZA ZA986629A patent/ZA986629B/xx unknown
- 1998-07-24 AR ARP980103661A patent/AR013255A1/es active IP Right Grant
- 1998-07-24 JP JP2000503828A patent/JP2001510792A/ja active Pending
- 1998-07-24 AU AU84938/98A patent/AU8493898A/en not_active Abandoned
- 1998-07-24 EP EP98935754A patent/EP0998273B1/en not_active Expired - Lifetime
- 1998-07-24 US US09/122,073 patent/US6524305B1/en not_active Expired - Lifetime
-
2000
- 2000-10-31 HK HK00106928A patent/HK1027752A1/xx not_active IP Right Cessation
-
2002
- 2002-10-25 US US10/279,957 patent/US6840931B2/en not_active Expired - Lifetime
-
2004
- 2004-11-22 US US10/994,615 patent/US7407500B2/en not_active Expired - Fee Related
-
2007
- 2007-09-16 US US11/856,050 patent/US20080071253A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
HK1027752A1 (en) | 2001-01-23 |
CN1198601C (zh) | 2005-04-27 |
US7407500B2 (en) | 2008-08-05 |
US6524305B1 (en) | 2003-02-25 |
AU8493898A (en) | 1999-02-16 |
WO1999004768A3 (en) | 1999-04-08 |
TW384226B (en) | 2000-03-11 |
US6840931B2 (en) | 2005-01-11 |
DE69826479D1 (de) | 2004-10-28 |
CA2297817A1 (en) | 1999-02-04 |
WO1999004768A2 (en) | 1999-02-04 |
EP0998273A2 (en) | 2000-05-10 |
DE69826479T2 (de) | 2005-09-29 |
DK0998273T3 (da) | 2005-01-31 |
EP0998273B1 (en) | 2004-09-22 |
ATE276747T1 (de) | 2004-10-15 |
CN1265030A (zh) | 2000-08-30 |
US20080071253A1 (en) | 2008-03-20 |
PT998273E (pt) | 2004-11-30 |
CA2297817C (en) | 2007-05-22 |
CO4890860A1 (es) | 2000-02-28 |
MY125870A (en) | 2006-08-30 |
ES2226159T3 (es) | 2005-03-16 |
US20030114837A1 (en) | 2003-06-19 |
JP2001510792A (ja) | 2001-08-07 |
KR100523201B1 (ko) | 2005-10-21 |
ZA986629B (en) | 1999-02-04 |
KR20010022223A (ko) | 2001-03-15 |
US20050131389A1 (en) | 2005-06-16 |
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