AR007493A1 - Microparticulas secadas por rociado como vehiculos terapeuticos para uso en terapia genetica - Google Patents
Microparticulas secadas por rociado como vehiculos terapeuticos para uso en terapia geneticaInfo
- Publication number
- AR007493A1 AR007493A1 ARP970101333A ARP970101333A AR007493A1 AR 007493 A1 AR007493 A1 AR 007493A1 AR P970101333 A ARP970101333 A AR P970101333A AR P970101333 A ARP970101333 A AR P970101333A AR 007493 A1 AR007493 A1 AR 007493A1
- Authority
- AR
- Argentina
- Prior art keywords
- spray dried
- genetic therapy
- dried microparticles
- therapeutic vehicles
- microparticles
- Prior art date
Links
- 239000011859 microparticle Substances 0.000 title abstract 2
- 230000002068 genetic effect Effects 0.000 title 1
- 239000007921 spray Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229940112141 dry powder inhaler Drugs 0.000 abstract 1
- 238000001415 gene therapy Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9607035.4A GB9607035D0 (en) | 1996-04-03 | 1996-04-03 | Spray-dried microparticles as therapeutic vehicles |
| GB9601379 | 1996-06-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR007493A1 true AR007493A1 (es) | 1999-11-10 |
Family
ID=26308516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970101333A AR007493A1 (es) | 1996-04-03 | 1997-04-03 | Microparticulas secadas por rociado como vehiculos terapeuticos para uso en terapia genetica |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0936902B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2000507568A (cg-RX-API-DMAC7.html) |
| AR (1) | AR007493A1 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE243027T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU715512B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2250478A1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE69722952T2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK0936902T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2201283T3 (cg-RX-API-DMAC7.html) |
| GB (1) | GB9607035D0 (cg-RX-API-DMAC7.html) |
| NO (1) | NO984462D0 (cg-RX-API-DMAC7.html) |
| PT (1) | PT936902E (cg-RX-API-DMAC7.html) |
| WO (1) | WO1997036578A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA972837B (cg-RX-API-DMAC7.html) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6051256A (en) | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
| JP2000500744A (ja) | 1995-11-09 | 2000-01-25 | マイクロバイオロジカル リサーチ オーソリティー | ワクチン接種および遺伝子治療のためのマイクロカプセル化dna |
| US6270795B1 (en) | 1995-11-09 | 2001-08-07 | Microbiological Research Authority | Method of making microencapsulated DNA for vaccination and gene therapy |
| US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| US6946117B1 (en) | 1997-09-29 | 2005-09-20 | Nektar Therapeutics | Stabilized preparations for use in nebulizers |
| US6433040B1 (en) | 1997-09-29 | 2002-08-13 | Inhale Therapeutic Systems, Inc. | Stabilized bioactive preparations and methods of use |
| US6309623B1 (en) | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
| US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| GB9810236D0 (en) | 1998-05-13 | 1998-07-08 | Microbiological Res Authority | Improvements relating to encapsulation of bioactive agents |
| US6406719B1 (en) | 1998-05-13 | 2002-06-18 | Microbiological Research Authority | Encapsulation of bioactive agents |
| US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
| TWI290473B (en) | 2000-05-10 | 2007-12-01 | Alliance Pharma | Phospholipid-based powders for drug delivery |
| US7575761B2 (en) | 2000-06-30 | 2009-08-18 | Novartis Pharma Ag | Spray drying process control of drying kinetics |
| AU2001291721A1 (en) * | 2000-08-25 | 2002-03-04 | Merck Patent G.M.B.H | Powdered mannitol and mannitol-containing compositions |
| TWI324518B (en) | 2001-12-19 | 2010-05-11 | Nektar Therapeutics | Pulmonary delivery of aminoglycosides |
| US9339459B2 (en) | 2003-04-24 | 2016-05-17 | Nektar Therapeutics | Particulate materials |
| US7884085B2 (en) | 2004-05-12 | 2011-02-08 | Baxter International Inc. | Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes |
| DK2072040T3 (da) | 2004-05-12 | 2013-07-29 | Baxter Healthcare Sa | Terapeutisk anvendelse af nukleinsyremikrokugler |
| EP1834651A1 (en) * | 2006-03-15 | 2007-09-19 | Universiteit Gent | Compositions and methods for veterinary vaccination |
| CA2942128C (en) | 2006-08-04 | 2019-11-26 | Baxter Healthcare S.A. | Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes |
| US8808747B2 (en) | 2007-04-17 | 2014-08-19 | Baxter International Inc. | Nucleic acid microparticles for pulmonary delivery |
| DE102009033196A1 (de) * | 2009-07-14 | 2011-01-20 | Beiersdorf Ag | Kosmetische Zubereitung mit einem Gehalt an dispergierten Mikrosphären |
| EP3826608A1 (en) * | 2018-07-23 | 2021-06-02 | Translate Bio, Inc. | Dry power formulations for messenger rna |
| EP3908264A1 (en) * | 2019-01-09 | 2021-11-17 | Ziccum AB | Stabilized non-enveloped virus compositions |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9107628D0 (en) * | 1991-04-10 | 1991-05-29 | Moonbrook Limited | Preparation of diagnostic agents |
| ATE204750T1 (de) * | 1992-06-12 | 2001-09-15 | Teijin Ltd | Pharmazeutische zubereitung zur anwendung in den atemwegen |
| ES2177544T3 (es) * | 1992-06-12 | 2002-12-16 | Teijin Ltd | Polvo ultrafinno para inhalar y metodo para su preparacion. |
| WO1994023699A1 (en) * | 1993-04-19 | 1994-10-27 | Medisorb Technologies International L.P. | Long-acting treatment by slow-release delivery of antisense oligodeoxyribonucleotides from biodegradable microparticles |
| ES2245780T3 (es) * | 1994-05-18 | 2006-01-16 | Nektar Therapeutics | Metodos y composiciones para la formulacion de interferones como un polvo seco. |
| MX9702357A (es) * | 1994-09-29 | 1997-06-28 | Andaris Ltd | Microparticulas secadas por aspersion como vehiculos terapeuticos. |
| WO1996027393A1 (en) * | 1995-03-07 | 1996-09-12 | University Of Pittsburgh | A dry powder formulation for gene therapy |
| CA2227287A1 (en) * | 1995-07-21 | 1997-02-06 | Brown University Research Foundation | A method for gene therapy using nucleic acid loaded polymeric microparticles |
-
1996
- 1996-04-03 GB GBGB9607035.4A patent/GB9607035D0/en active Pending
-
1997
- 1997-04-03 WO PCT/GB1997/000953 patent/WO1997036578A1/en not_active Ceased
- 1997-04-03 ZA ZA9702837A patent/ZA972837B/xx unknown
- 1997-04-03 AT AT97915601T patent/ATE243027T1/de not_active IP Right Cessation
- 1997-04-03 PT PT97915601T patent/PT936902E/pt unknown
- 1997-04-03 AU AU23020/97A patent/AU715512B2/en not_active Ceased
- 1997-04-03 ES ES97915601T patent/ES2201283T3/es not_active Expired - Lifetime
- 1997-04-03 DK DK97915601T patent/DK0936902T3/da active
- 1997-04-03 EP EP97915601A patent/EP0936902B1/en not_active Expired - Lifetime
- 1997-04-03 JP JP9535066A patent/JP2000507568A/ja active Pending
- 1997-04-03 DE DE69722952T patent/DE69722952T2/de not_active Expired - Fee Related
- 1997-04-03 AR ARP970101333A patent/AR007493A1/es not_active Application Discontinuation
- 1997-04-03 CA CA002250478A patent/CA2250478A1/en not_active Abandoned
-
1998
- 1998-09-25 NO NO984462A patent/NO984462D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2250478A1 (en) | 1997-10-09 |
| PT936902E (pt) | 2003-11-28 |
| WO1997036578A1 (en) | 1997-10-09 |
| AU2302097A (en) | 1997-10-22 |
| AU715512B2 (en) | 2000-02-03 |
| ES2201283T3 (es) | 2004-03-16 |
| ATE243027T1 (de) | 2003-07-15 |
| DK0936902T3 (da) | 2003-10-06 |
| EP0936902B1 (en) | 2003-06-18 |
| NO984462L (no) | 1998-09-25 |
| DE69722952T2 (de) | 2003-12-11 |
| JP2000507568A (ja) | 2000-06-20 |
| GB9607035D0 (en) | 1996-06-05 |
| EP0936902A1 (en) | 1999-08-25 |
| ZA972837B (en) | 1998-04-03 |
| NO984462D0 (no) | 1998-09-25 |
| DE69722952D1 (de) | 2003-07-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |