DK0936902T3 - Spraytørrede mikropartikler som terapeutiske bærere til anvendelse i terapi - Google Patents

Spraytørrede mikropartikler som terapeutiske bærere til anvendelse i terapi

Info

Publication number
DK0936902T3
DK0936902T3 DK97915601T DK97915601T DK0936902T3 DK 0936902 T3 DK0936902 T3 DK 0936902T3 DK 97915601 T DK97915601 T DK 97915601T DK 97915601 T DK97915601 T DK 97915601T DK 0936902 T3 DK0936902 T3 DK 0936902T3
Authority
DK
Denmark
Prior art keywords
therapy
spray
dried microparticles
therapeutic carriers
carriers
Prior art date
Application number
DK97915601T
Other languages
Danish (da)
English (en)
Inventor
Andrew Derek Sutton
Jill Elizabeth Ogden
Richard Alan Johnson
Original Assignee
Elan Drug Delivery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Drug Delivery Ltd filed Critical Elan Drug Delivery Ltd
Application granted granted Critical
Publication of DK0936902T3 publication Critical patent/DK0936902T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277Preparation processes; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK97915601T 1996-04-03 1997-04-03 Spraytørrede mikropartikler som terapeutiske bærere til anvendelse i terapi DK0936902T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9607035.4A GB9607035D0 (en) 1996-04-03 1996-04-03 Spray-dried microparticles as therapeutic vehicles
GB9601379 1996-06-07
PCT/GB1997/000953 WO1997036578A1 (en) 1996-04-03 1997-04-03 Spray-dried microparticles as therapeutic vehicles for use in gene therapy

Publications (1)

Publication Number Publication Date
DK0936902T3 true DK0936902T3 (da) 2003-10-06

Family

ID=26308516

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97915601T DK0936902T3 (da) 1996-04-03 1997-04-03 Spraytørrede mikropartikler som terapeutiske bærere til anvendelse i terapi

Country Status (14)

Country Link
EP (1) EP0936902B1 (cg-RX-API-DMAC7.html)
JP (1) JP2000507568A (cg-RX-API-DMAC7.html)
AR (1) AR007493A1 (cg-RX-API-DMAC7.html)
AT (1) ATE243027T1 (cg-RX-API-DMAC7.html)
AU (1) AU715512B2 (cg-RX-API-DMAC7.html)
CA (1) CA2250478A1 (cg-RX-API-DMAC7.html)
DE (1) DE69722952T2 (cg-RX-API-DMAC7.html)
DK (1) DK0936902T3 (cg-RX-API-DMAC7.html)
ES (1) ES2201283T3 (cg-RX-API-DMAC7.html)
GB (1) GB9607035D0 (cg-RX-API-DMAC7.html)
NO (1) NO984462D0 (cg-RX-API-DMAC7.html)
PT (1) PT936902E (cg-RX-API-DMAC7.html)
WO (1) WO1997036578A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA972837B (cg-RX-API-DMAC7.html)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
JP2000500744A (ja) 1995-11-09 2000-01-25 マイクロバイオロジカル リサーチ オーソリティー ワクチン接種および遺伝子治療のためのマイクロカプセル化dna
US6270795B1 (en) 1995-11-09 2001-08-07 Microbiological Research Authority Method of making microencapsulated DNA for vaccination and gene therapy
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6946117B1 (en) 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
US6433040B1 (en) 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
GB9810236D0 (en) 1998-05-13 1998-07-08 Microbiological Res Authority Improvements relating to encapsulation of bioactive agents
US6406719B1 (en) 1998-05-13 2002-06-18 Microbiological Research Authority Encapsulation of bioactive agents
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
TWI290473B (en) 2000-05-10 2007-12-01 Alliance Pharma Phospholipid-based powders for drug delivery
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
AU2001291721A1 (en) * 2000-08-25 2002-03-04 Merck Patent G.M.B.H Powdered mannitol and mannitol-containing compositions
TWI324518B (en) 2001-12-19 2010-05-11 Nektar Therapeutics Pulmonary delivery of aminoglycosides
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
US7884085B2 (en) 2004-05-12 2011-02-08 Baxter International Inc. Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes
DK2072040T3 (da) 2004-05-12 2013-07-29 Baxter Healthcare Sa Terapeutisk anvendelse af nukleinsyremikrokugler
EP1834651A1 (en) * 2006-03-15 2007-09-19 Universiteit Gent Compositions and methods for veterinary vaccination
CA2942128C (en) 2006-08-04 2019-11-26 Baxter Healthcare S.A. Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes
US8808747B2 (en) 2007-04-17 2014-08-19 Baxter International Inc. Nucleic acid microparticles for pulmonary delivery
DE102009033196A1 (de) * 2009-07-14 2011-01-20 Beiersdorf Ag Kosmetische Zubereitung mit einem Gehalt an dispergierten Mikrosphären
EP3826608A1 (en) * 2018-07-23 2021-06-02 Translate Bio, Inc. Dry power formulations for messenger rna
EP3908264A1 (en) * 2019-01-09 2021-11-17 Ziccum AB Stabilized non-enveloped virus compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9107628D0 (en) * 1991-04-10 1991-05-29 Moonbrook Limited Preparation of diagnostic agents
ATE204750T1 (de) * 1992-06-12 2001-09-15 Teijin Ltd Pharmazeutische zubereitung zur anwendung in den atemwegen
ES2177544T3 (es) * 1992-06-12 2002-12-16 Teijin Ltd Polvo ultrafinno para inhalar y metodo para su preparacion.
WO1994023699A1 (en) * 1993-04-19 1994-10-27 Medisorb Technologies International L.P. Long-acting treatment by slow-release delivery of antisense oligodeoxyribonucleotides from biodegradable microparticles
ES2245780T3 (es) * 1994-05-18 2006-01-16 Nektar Therapeutics Metodos y composiciones para la formulacion de interferones como un polvo seco.
MX9702357A (es) * 1994-09-29 1997-06-28 Andaris Ltd Microparticulas secadas por aspersion como vehiculos terapeuticos.
WO1996027393A1 (en) * 1995-03-07 1996-09-12 University Of Pittsburgh A dry powder formulation for gene therapy
CA2227287A1 (en) * 1995-07-21 1997-02-06 Brown University Research Foundation A method for gene therapy using nucleic acid loaded polymeric microparticles

Also Published As

Publication number Publication date
CA2250478A1 (en) 1997-10-09
PT936902E (pt) 2003-11-28
WO1997036578A1 (en) 1997-10-09
AU2302097A (en) 1997-10-22
AU715512B2 (en) 2000-02-03
ES2201283T3 (es) 2004-03-16
ATE243027T1 (de) 2003-07-15
EP0936902B1 (en) 2003-06-18
NO984462L (no) 1998-09-25
AR007493A1 (es) 1999-11-10
DE69722952T2 (de) 2003-12-11
JP2000507568A (ja) 2000-06-20
GB9607035D0 (en) 1996-06-05
EP0936902A1 (en) 1999-08-25
ZA972837B (en) 1998-04-03
NO984462D0 (no) 1998-09-25
DE69722952D1 (de) 2003-07-24

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