AR004683A1 - Nuevos esteres de la dehidroepiandrosterona (dhea) composiciones para tratar desordenes de la piel y/o regular atrofias de la misma y metodo deaplicacionn de dichas composiciones. - Google Patents

Nuevos esteres de la dehidroepiandrosterona (dhea) composiciones para tratar desordenes de la piel y/o regular atrofias de la misma y metodo deaplicacionn de dichas composiciones.

Info

Publication number
AR004683A1
AR004683A1 ARP960104328A AR10432896A AR004683A1 AR 004683 A1 AR004683 A1 AR 004683A1 AR P960104328 A ARP960104328 A AR P960104328A AR 10432896 A AR10432896 A AR 10432896A AR 004683 A1 AR004683 A1 AR 004683A1
Authority
AR
Argentina
Prior art keywords
skin
compositions
alkyl
dhea
dehydroepiandrosterone
Prior art date
Application number
ARP960104328A
Other languages
English (en)
Original Assignee
Estee Lauder Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Estee Lauder Inc filed Critical Estee Lauder Inc
Publication of AR004683A1 publication Critical patent/AR004683A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/006—Antidandruff preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se proponen nuevos ésteres de la dehidroepiandrosterona (DHEA) de fórmula (II) o las sales farmacéutica o cosméticamente aceptables del mismo, endonde; R es A(CH(OH)-C(O) ó (HO)C6H4C(O)-; y A es hidrógeno o un grupo C1-C22 -alquilo oalqu enilo, siendo posible que dicho grupo C1-C22-alquilo oalquenilo sea sustituido de manera opcional por uno o más grupos C1-C4-alquilo, fenilos, halógenos o grupos hidroxilo, pudiendo dichos fenilos ser sustituidosde manera opcional por uno o máshalóg enos, grupos hidroxilos o grupos metoxilo. Dichos compuestos, especialmente el salicilato son útiles paratratar estados de atrofia de la iel, incluyendo el adelgazamiento y/o la degradación general de la dermis, a menudocaracterizada por una disminucióndel cológeno y/o de la elastina, así como también por una disminución en cuanto a número, tamano y potencial de duplicación de las célulasfibroblásticas.Las citadas enfermedades incluyen (pero no se agotan en)la piel seca, la caspa, el acné, la queratosis, la psoriasis, el eczema, el prurito,las manchas de la vejez, las pecas, los melasmas, las arrugas (de ambos tipos grueso y fino) causados tanto por dano extrínseco como intrínseco),la verrugas,lapiel manchada, la piel hiper-pigmentada, la piel hiperqueratósica, la dermatosis inflamatoria, las modificaciones de la piel relacionadas con laedad, y la piel que necesita limpieza. Se propone también una composición que contiene elcompuesto activo y métod o de aplicación de la misma.
ARP960104328A 1995-09-12 1996-09-12 Nuevos esteres de la dehidroepiandrosterona (dhea) composiciones para tratar desordenes de la piel y/o regular atrofias de la misma y metodo deaplicacionn de dichas composiciones. AR004683A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/527,145 US5736537A (en) 1995-09-12 1995-09-12 Dehydroep:androsterone sailcylate useful against skin atrophy

Publications (1)

Publication Number Publication Date
AR004683A1 true AR004683A1 (es) 1999-03-10

Family

ID=24100286

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960104328A AR004683A1 (es) 1995-09-12 1996-09-12 Nuevos esteres de la dehidroepiandrosterona (dhea) composiciones para tratar desordenes de la piel y/o regular atrofias de la misma y metodo deaplicacionn de dichas composiciones.

Country Status (12)

Country Link
US (3) US5736537A (es)
EP (1) EP0876391B1 (es)
AR (1) AR004683A1 (es)
AT (1) ATE195527T1 (es)
AU (1) AU712977B2 (es)
CA (1) CA2231781C (es)
CO (1) CO4770981A1 (es)
DE (1) DE69609868T2 (es)
ES (1) ES2151180T3 (es)
IL (1) IL123637A (es)
WO (1) WO1997010255A1 (es)
ZA (1) ZA967704B (es)

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FR2996133B1 (fr) 2012-10-02 2015-06-26 Oreal Nouvelles utilisations cosmetiques de polymeres dispersants en association avec au moins un actif
JP2016521544A (ja) 2013-05-21 2016-07-25 ドクター レディズ ラボラトリーズ リミテッド デヒドロエピアンドロステロンおよびその中間体の調製法。
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Also Published As

Publication number Publication date
HK1015794A1 (en) 1999-10-22
AU712977B2 (en) 1999-11-18
IL123637A0 (en) 1998-10-30
US6284750B1 (en) 2001-09-04
CA2231781A1 (en) 1997-03-20
US5736537A (en) 1998-04-07
ATE195527T1 (de) 2000-09-15
DE69609868T2 (de) 2001-03-15
IL123637A (en) 2003-03-12
CA2231781C (en) 2005-07-12
ZA967704B (en) 1997-05-27
WO1997010255A1 (en) 1997-03-20
ES2151180T3 (es) 2000-12-16
AU6966996A (en) 1997-04-01
CO4770981A1 (es) 1999-04-30
EP0876391B1 (en) 2000-08-16
DE69609868D1 (de) 2000-09-21
EP0876391A4 (en) 1998-12-30
EP0876391A1 (en) 1998-11-11
US6025347A (en) 2000-02-15

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