AR004567A1 - Metodos para detectar la infeccion de t.cruzi, en una muestra biologica, un vector de expresion recombinante, un microorganismo modificado, un kit de diagnostico, una composicion farmaceutica, el uso de la composicion farmaceutica para la preparacion de un medicamento para estimular la produccion de anticuerpos que se liguen a t. cruzi. - Google Patents
Metodos para detectar la infeccion de t.cruzi, en una muestra biologica, un vector de expresion recombinante, un microorganismo modificado, un kit de diagnostico, una composicion farmaceutica, el uso de la composicion farmaceutica para la preparacion de un medicamento para estimular la produccion de anticuerpos que se liguen a t. cruzi.Info
- Publication number
- AR004567A1 AR004567A1 ARP960105145A ARP960105145A AR004567A1 AR 004567 A1 AR004567 A1 AR 004567A1 AR P960105145 A ARP960105145 A AR P960105145A AR P960105145 A ARP960105145 A AR P960105145A AR 004567 A1 AR004567 A1 AR 004567A1
- Authority
- AR
- Argentina
- Prior art keywords
- cruzi
- antibodies
- pharmaceutical composition
- methods
- diagnostic kit
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56905—Protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Veterinary Medicine (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Se describen métodos para diagnosticar la infección de Trypanosoma cruzi, polipéptidos o anticuerpos del mismo que contienen uno o más epítopes deantígenos de T.cruzi. Los polipéptidos son útiles en una variedad de inmunoensayos paradete ctar la infección de T.cruzi. Los polipéptidos sonútiles, además, en vacunas y en composiciones farmacéuticas para inducir inmunidad protectora contra la enfermedad de Chagas en individuos expuestos aT. cruzi. También se refiere a unasecuenci a de ADN aislada, un vector de expresión, una célula huésped, un kit de diagnóstico, una composiciónfarmacéutica, una vacuna para estimular la producción de anticuerpos que se liguen a T.cruzi.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/557,309 US5916572A (en) | 1995-11-14 | 1995-11-14 | Compounds and methods for the detection and prevention of T. cruzi infection |
Publications (1)
Publication Number | Publication Date |
---|---|
AR004567A1 true AR004567A1 (es) | 1998-12-16 |
Family
ID=24224889
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP960105145A AR004567A1 (es) | 1995-11-14 | 1996-11-12 | Metodos para detectar la infeccion de t.cruzi, en una muestra biologica, un vector de expresion recombinante, un microorganismo modificado, un kit de diagnostico, una composicion farmaceutica, el uso de la composicion farmaceutica para la preparacion de un medicamento para estimular la produccion de anticuerpos que se liguen a t. cruzi. |
Country Status (14)
Country | Link |
---|---|
US (1) | US5916572A (es) |
EP (1) | EP0874992B1 (es) |
JP (1) | JP2000503111A (es) |
AR (1) | AR004567A1 (es) |
AT (1) | ATE213544T1 (es) |
AU (1) | AU722152B2 (es) |
BR (1) | BRPI9611455B8 (es) |
CA (1) | CA2237299A1 (es) |
DE (1) | DE69619405T2 (es) |
DK (1) | DK0874992T3 (es) |
ES (1) | ES2168520T3 (es) |
MX (1) | MX9803841A (es) |
PT (1) | PT874992E (es) |
WO (1) | WO1997018475A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6403103B1 (en) * | 1994-08-12 | 2002-06-11 | Bio Merieux | Trypanosoma cruzi antigen, gene encoding therefore, and methods of detecting and treating chagas disease |
US6228372B1 (en) | 1997-04-15 | 2001-05-08 | Corixa Corporation | Compounds and methods for the detection and prevention of T. cruzi infection |
US6419933B1 (en) | 1995-11-14 | 2002-07-16 | Corixa Corporation | Compounds and methods for the detection and prevention of T.cruzi infection |
WO1999005528A1 (en) * | 1997-07-28 | 1999-02-04 | Immunetics | Assay and device for identifying trypanosoma cruzi infection |
US6908898B1 (en) * | 1998-06-15 | 2005-06-21 | Lars Holmgren | Angiogenesis related molecules |
EP0976763B1 (en) * | 1998-07-30 | 2003-11-05 | Innogenetics N.V. | Antigens and immunoassays for diagnosing Chagas' disease |
FR2788527A1 (fr) | 1999-01-15 | 2000-07-21 | Bio Merieux | Pseudopeptide, procede de synthese, reactif et applications |
PE20050942A1 (es) * | 2003-12-04 | 2005-11-10 | Louis V Kirchhoff | Polipeptidos recombinantes para diagnosticar la infeccion con el trypanosoma cruzi |
US7749717B2 (en) * | 2006-10-19 | 2010-07-06 | Abbott Laboratories | Methods for the detection and diagnosis of Trypanosoma cruzi infection |
WO2010000849A2 (en) * | 2008-07-04 | 2010-01-07 | Institut De Recherche Pour Le Developpement (I.R.D.) | A method for the screening of conserved secreted proteins |
FR2945290A1 (fr) * | 2009-05-07 | 2010-11-12 | Maan Zrein | Anticorps biomarqueur et dispositif de diagnostic pour la detection de certaines maladies auto-immunes |
FR2958753B1 (fr) | 2010-04-13 | 2018-03-16 | Institut De Recherche Pour Le Developpement (Ird) | Construction antigenique et ses applications pour le depistage de trypanosomoses chez l'homme et l'animal |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4870006A (en) * | 1986-07-24 | 1989-09-26 | Codon | Antigenic material for a chagas' disease detection system |
WO1990002564A1 (en) * | 1988-09-12 | 1990-03-22 | Codon | Vaccine diagnostic employing proteins homologous to heat shock proteins of trypanosoma cruzi |
BR9006039A (pt) * | 1990-11-28 | 1992-07-14 | Fundacao Oswaldo Cruz | Processo para preparacao de antigeno conjugado a atividade enzimatica,composicao a base de conjugado enzima-antigeno para utilizacao em diagnostico imunologico e kits de diagnostico imunologico da doenca de chagas a base da dita composicao,para aplicacao individual e/ou em inqueritos epidemiologicos |
US5304371A (en) * | 1992-02-14 | 1994-04-19 | Lasys Corporation | Peptide for diagnosing and immunizing against T. cruzi infection |
TW246717B (es) * | 1992-07-10 | 1995-05-01 | Abbott Lab | |
US5756662A (en) * | 1995-03-14 | 1998-05-26 | Corixa Corporation | Compounds and methods for the detection of T. cruzi infection |
-
1995
- 1995-11-14 US US08/557,309 patent/US5916572A/en not_active Expired - Lifetime
-
1996
- 1996-11-12 AR ARP960105145A patent/AR004567A1/es active IP Right Grant
- 1996-11-14 PT PT96941416T patent/PT874992E/pt unknown
- 1996-11-14 AU AU10568/97A patent/AU722152B2/en not_active Ceased
- 1996-11-14 JP JP9519161A patent/JP2000503111A/ja active Pending
- 1996-11-14 WO PCT/US1996/018624 patent/WO1997018475A1/en active IP Right Grant
- 1996-11-14 DK DK96941416T patent/DK0874992T3/da active
- 1996-11-14 ES ES96941416T patent/ES2168520T3/es not_active Expired - Lifetime
- 1996-11-14 CA CA002237299A patent/CA2237299A1/en not_active Abandoned
- 1996-11-14 BR BRPI9611455-0B8A patent/BRPI9611455B8/pt not_active IP Right Cessation
- 1996-11-14 AT AT96941416T patent/ATE213544T1/de not_active IP Right Cessation
- 1996-11-14 DE DE69619405T patent/DE69619405T2/de not_active Expired - Fee Related
- 1996-11-14 EP EP96941416A patent/EP0874992B1/en not_active Expired - Lifetime
-
1998
- 1998-05-14 MX MX9803841A patent/MX9803841A/es unknown
Also Published As
Publication number | Publication date |
---|---|
BR9611455A (pt) | 2001-01-02 |
EP0874992A1 (en) | 1998-11-04 |
US5916572A (en) | 1999-06-29 |
DE69619405T2 (de) | 2002-10-17 |
DK0874992T3 (da) | 2002-03-25 |
MX9803841A (es) | 1998-09-30 |
BRPI9611455B1 (pt) | 2008-11-04 |
CA2237299A1 (en) | 1997-05-22 |
WO1997018475A1 (en) | 1997-05-22 |
AU722152B2 (en) | 2000-07-20 |
BRPI9611455B8 (pt) | 2014-07-01 |
ATE213544T1 (de) | 2002-03-15 |
JP2000503111A (ja) | 2000-03-14 |
DE69619405D1 (de) | 2002-03-28 |
ES2168520T3 (es) | 2002-06-16 |
PT874992E (pt) | 2002-08-30 |
AU1056897A (en) | 1997-06-05 |
EP0874992B1 (en) | 2002-02-20 |
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